By Dr Jason Ciril Kovacic

Journal articles

Mahajan AM; Claessen BE; Chandrasekhar J; Sartori S; Aquino M; Baber U; Dangas G; Kovacic JC; Krishnan P; Moreno P; Sweeny J; Barman N; Vijay P; Kini A; Mehran R; Sharma S, 2019, 'Outcomes by Gender and Ethnicity After Percutaneous Coronary Intervention', American Journal of Cardiology, 123, pp. 1941 - 1948, http://dx.doi.org/10.1016/j.amjcard.2019.03.019

Guedeney P; Claessen BE; Baber U; Camaj A; Sorrentino S; Aquino M; Blum M; Chandiramani R; Goel R; Elsayed S; Kovacic JC; Sweeny J; Barman N; Moreno P; Dangas GD; Kini A; Sharma S; Mehran R, 2019, 'Temporal Trends in Statin Prescriptions and Residual Cholesterol Risk in Patients With Stable Coronary Artery Disease Undergoing Percutaneous Coronary Intervention', American Journal of Cardiology, 123, pp. 1788 - 1795, http://dx.doi.org/10.1016/j.amjcard.2019.03.005

Guedeney P; Claessen BE; Kalkman DN; Aquino M; Sorrentino S; Giustino G; Farhan S; Vogel B; Sartori S; Montalescot G; Sweeny J; Kovacic JC; Krishnan P; Barman N; Dangas G; Kini A; Baber U; Sharma S; Mehran R, 2019, 'Residual Inflammatory Risk in Patients With Low LDL Cholesterol Levels Undergoing Percutaneous Coronary Intervention', Journal of the American College of Cardiology, 73, pp. 2401 - 2409, http://dx.doi.org/10.1016/j.jacc.2019.01.077

Price LZ; Faries PL; McKinsey JF; Prakash K; Tang GH; Kovacic JC; Tadros RO, 2019, 'The Epidemiology, Pathophysiology, and Novel Treatment of Calcific Arterial Disease', Surgical technology international, 34, pp. 351 - 358

Fernandez-Jimenez R; Jaslow R; Bansilal S; Santana M; Diaz-Munoz R; Latina J; Soto AV; Vedanthan R; Al-Kazaz M; Giannarelli C; Kovacic JC; Bagiella E; Kasarskis A; Fayad ZA; Hajjar RJ; Fuster V, 2019, 'Child Health Promotion in Underserved Communities: The FAMILIA Trial', Journal of the American College of Cardiology, 73, pp. 2011 - 2021, http://dx.doi.org/10.1016/j.jacc.2019.01.057

Zhang Z; Cheng H; Hong X; DI Narzo AF; Franzen O; Peng S; Ruusalepp A; Kovacic JC; Bjorkegren JLM; Wang X; Hao K, 2019, 'EnsembleCNV: An ensemble machine learning algorithm to identify and genotype copy number variation using SNP array data', Nucleic Acids Research, 47, http://dx.doi.org/10.1093/nar/gkz068

Gornik HL; Persu A; Adlam D; Aparicio LS; Azizi M; Boulanger M; Bruno RM; de Leeuw P; Fendrikova-Mahlay N; Froehlich J; Ganesh SK; Gray BH; Jamison C; Januszewicz A; Jeunemaitre X; Kadian-Dodov D; Kim ESH; Kovacic JC; Mace P; Morganti A; Sharma A; Southerland AM; Touzé E; van der Niepen P; Wang J; Weinberg I; Wilson S; Olin JW; Plouin PF, 2019, 'First International Consensus on the diagnosis and management of fibromuscular dysplasia', Vascular Medicine (United Kingdom), 24, pp. 164 - 189, http://dx.doi.org/10.1177/1358863X18821816

Kovacic JC; Dimmeler S; Harvey RP; Finkel T; Aikawa E; Krenning G; Baker AH, 2019, 'Endothelial to Mesenchymal Transition in Cardiovascular Disease: JACC State-of-the-Art Review', Journal of the American College of Cardiology, 73, pp. 190 - 209, http://dx.doi.org/10.1016/j.jacc.2018.09.089

Adlam D; Olson TM; Combaret N; Kovacic JC; Iismaa SE; Al-Hussaini A; O'Byrne MM; Bouajila S; Georges A; Mishra K; Braund PS; d'Escamard V; Huang S; Margaritis M; Nelson CP; de Andrade M; Kadian-Dodov D; Welch CA; Mazurkiewicz S; Jeunemaitre X; Motreff P; Belle L; Dupouy P; Barnay P; Meneveau N; Gilard M; Rioufol G; Range G; Brunel P; Delarche N; Filippi E; Le Bivic L; Harbaoui B; Benamer H; Cayla G; Varenne O; Manzo-Silberman SP; Silvain J; Spaulding C; Caussin C; Gerbaud E; Valy Y; Koning R; Lhermusier T; Champin S; Salengro E; Fluttaz A; Zabalawi A; Cottin Y; Teiger E; Saint-Etienne C; Ducrocq G; Marliere S; Boiffard E; Aubry P; Georges JL; Bresson D; De Poli F; Karrillon G; Roule V; Bali L; Valla M; Gerbay A; Houpe D; Dubreuil O; Monnier A; Mayaud N; Manchuelle A; Commeau P; Bedossa M; Wong CMY; Giannoulatou E; Sweeting M; Muller D; Wood A; McGrath-Cadell L; Fatkin D; Dunwoodie SL; Harvey R; Holloway C; Empana JP; Jouven X; Nikpay M; Goel A; Won HH; Hall LM; Willenborg C; Kanoni S; Saleheen D; Kyriakou T; Hopewell JC; Webb TR; Zeng L; Dehghan A; Alver M; Armasu SM; Auro K; Bjonnes A; Chasman DI; Chen S, 2019, 'Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection', Journal of the American College of Cardiology, 73, pp. 58 - 66, http://dx.doi.org/10.1016/j.jacc.2018.09.085

Gornik HL; Persu A; Adlam D; Aparicio LS; Azizi M; Boulanger M; Bruno RM; De Leeuw P; Fendrikova-Mahlay N; Froehlich J; Ganesh SK; Gray BH; Jamison C; Januszewicz A; Jeunemaitre X; Kadian-Dodov D; Kim ESH; Kovacic JC; MacE P; Morganti A; Sharma A; Southerland AM; Touzé E; Van Der Niepen P; Wang J; Weinberg I; Wilson S; Olin JW; Plouin PF, 2019, 'First international consensus on the diagnosis and management of fibromuscular dysplasia', Journal of Hypertension, 37, pp. 229 - 252, http://dx.doi.org/10.1097/HJH.0000000000002019

Frades I; Readhead B; Amadori L; Koplev S; Talukdar HA; Crane HM; Crane PK; Kovacic JC; Dudley JT; Giannarelli C; Björkegren JLM; Peter I, 2019, 'Systems pharmacology identifies an arterial wall regulatory gene network mediating coronary artery disease side effects of antiretroviral therapy', Circulation: Genomic and Precision Medicine, 12, pp. 262 - 272, http://dx.doi.org/10.1161/CIRCGEN.118.002390

Guedeney P; Baber U; Claessen B; Aquino M; Camaj A; Sorrentino S; Vogel B; Farhan S; Faggioni M; Chandrasekhar J; Kalkman DN; Kovacic JC; Sweeny J; Barman N; Moreno P; Vijay P; Shah S; Dangas G; Kini A; Sharma S; Mehran R, 2019, 'Temporal trends, determinants, and impact of high-intensity statin prescriptions after percutaneous coronary intervention: Results from a large single-center prospective registry', American Heart Journal, 207, pp. 10 - 18, http://dx.doi.org/10.1016/j.ahj.2018.09.001

Kalkman DN; Aquino M; Claessen BE; Baber U; Guedeney P; Sorrentino S; Vogel B; De Winter RJ; Sweeny J; Kovacic JC; Shah S; Vijay P; Barman N; Kini A; Sharma S; Dangas GD; Mehran R, 2018, 'Residual inflammatory risk and the impact on clinical outcomes in patients after percutaneous coronary interventions', European Heart Journal, 39, pp. 4101 - 4108, http://dx.doi.org/10.1093/eurheartj/ehy633

Peng S; Deyssenroth MA; Di Narzo AF; Cheng H; Zhang Z; Lambertini L; Rusualepp A; Kovacic JC; Bjorkegren JLM; Marsit CJ; Chen J; Hao K, 2018, 'Genetic regulation of the placental transcriptome underlies birth weight and risk of childhood obesity', PLoS Genetics, 14, http://dx.doi.org/10.1371/journal.pgen.1007799

Robson PM; Trivieri MG; Karakatsanis NA; Padilla M; Abgral R; Dweck MR; Kovacic JC; Fayad ZA, 2018, 'Correction of respiratory and cardiac motion in cardiac PET/MR using MR-based motion modeling', Physics in Medicine and Biology, 63, http://dx.doi.org/10.1088/1361-6560/aaea97

Williams JW; Giannarelli C; Rahman A; Randolph GJ; Kovacic JC, 2018, 'Macrophage Biology, Classification, and Phenotype in Cardiovascular Disease: JACC Macrophage in CVD Series (Part 1)', Journal of the American College of Cardiology, 72, pp. 2166 - 2180, http://dx.doi.org/10.1016/j.jacc.2018.08.2148

Moore KJ; Koplev S; Fisher EA; Tabas I; Björkegren JLM; Doran AC; Kovacic JC, 2018, 'Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part 2)', Journal of the American College of Cardiology, 72, pp. 2181 - 2197, http://dx.doi.org/10.1016/j.jacc.2018.08.2147

Fayad ZA; Swirski FK; Calcagno C; Robbins CS; Mulder W; Kovacic JC, 2018, 'Monocyte and Macrophage Dynamics in the Cardiovascular System: JACC Macrophage in CVD Series (Part 3)', Journal of the American College of Cardiology, 72, pp. 2198 - 2212, http://dx.doi.org/10.1016/j.jacc.2018.08.2150

Lavine KJ; Pinto AR; Epelman S; Kopecky BJ; Clemente-Casares X; Godwin J; Rosenthal N; Kovacic JC, 2018, 'The Macrophage in Cardiac Homeostasis and Disease: JACC Macrophage in CVD Series (Part 4)', Journal of the American College of Cardiology, 72, pp. 2213 - 2230, http://dx.doi.org/10.1016/j.jacc.2018.08.2149

Kovacic JC, 2018, 'The Endothelial–Metabolic Axis: A Novel Cardiometabolic Disease Target', Trends in Endocrinology and Metabolism, 29, pp. 527 - 529, http://dx.doi.org/10.1016/j.tem.2018.03.015

Michelis KC; Nomura-Kitabayashi A; Lecce L; Franzén O; Koplev S; Xu Y; Santini MP; D'Escamard V; Lee JTL; Fuster V; Hajjar R; Reddy RC; Chikwe J; Stelzer P; Filsoufi F; Stewart A; Anyanwu A; Björkegren JLM; Kovacic JC, 2018, 'CD90 Identifies Adventitial Mesenchymal Progenitor Cells in Adult Human Medium- and Large-Sized Arteries', Stem Cell Reports, 11, pp. 242 - 257, http://dx.doi.org/10.1016/j.stemcr.2018.06.001

Sherifi I; Omar AMS; Varghese M; Weiner M; Anyanwu A; Kovacic JC; Sharma S; Kini A; Sengupta PP, 2018, 'Comparison of transesophageal and transthoracic echocardiography under moderate sedation for guiding transcatheter aortic valve replacement', Echo Research and Practice, 5, pp. 79 - 87, http://dx.doi.org/10.1530/ERP-17-0080

Copeland-Halperin RS; Baber U; Aquino M; Rajamanickam A; Roy S; Hasan C; Barman N; Kovacic JC; Moreno P; Krishnan P; Sweeny JM; Mehran R; Dangas G; Kini AS; Sharma SK, 2018, 'Prevalence, correlates, and impact of coronary calcification on adverse events following PCI with newer-generation DES: Findings from a large multiethnic registry', Catheterization and Cardiovascular Interventions, 91, pp. 859 - 866, http://dx.doi.org/10.1002/ccd.27204

Watanabe S; Fish K; Kovacic JC; Bikou O; Leonardson L; Nomoto K; Aguero J; Kapur NK; Hajjar RJ; Ishikawa K, 2018, 'Left ventricular unloading using an impella CP improves coronary flow and infarct zone perfusion in ischemic heart failure', Journal of the American Heart Association, 7, http://dx.doi.org/10.1161/JAHA.117.006462

Franzén O; Ermel R; Sukhavasi K; Jain R; Jain A; Betsholtz C; Giannarelli C; Kovacic JC; Ruusalepp A; Skogsberg J; Hao K; Schadt EE; Björkegren JLM, 2018, 'Global analysis of A-to-I RNA editing reveals association with common disease variants', PeerJ, 2018, http://dx.doi.org/10.7717/peerj.4466

Dweck MR; Abgral R; Trivieri MG; Robson PM; Karakatsanis N; Mani V; Palmisano A; Miller MA; Lala A; Chang HL; Sanz J; Contreras J; Narula J; Fuster V; Padilla M; Fayad ZA; Kovacic JC, 2018, 'Hybrid Magnetic Resonance Imaging and Positron Emission Tomography With Fluorodeoxyglucose to Diagnose Active Cardiac Sarcoidosis', JACC: Cardiovascular Imaging, 11, pp. 94 - 107, http://dx.doi.org/10.1016/j.jcmg.2017.02.021

Hajjar RJ; Ishikawa K; Kovacic JC; Fuster V, 2017, 'Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai Translational Mission', Circulation Research, 121, pp. 1316 - 1319, http://dx.doi.org/10.1161/CIRCRESAHA.117.311372

Pena J; Vengrenyuk Y; Kezbor S; Yoshimura T; Kovacic JC; Sharma SK; Baber U; Kini AS; Narula J; Moreno PR, 2017, 'Increased Lipid Length, Macrophage Infiltration, and Neovascularization in Coronary Atheroma From Patients With Chronic Kidney Disease', JACC: Cardiovascular Imaging, 10, pp. 1524 - 1526, http://dx.doi.org/10.1016/j.jcmg.2017.01.019

Robson PM; Dweck MR; Trivieri MG; Abgral R; Karakatsanis NA; Contreras J; Gidwani U; Narula JP; Fuster V; Kovacic JC; Fayad ZA, 2017, 'Coronary Artery PET/MR Imaging: Feasibility, Limitations, and Solutions', JACC: Cardiovascular Imaging, 10, pp. 1103 - 1112, http://dx.doi.org/10.1016/j.jcmg.2016.09.029

Sack MN; Fyhrquist FY; Saijonmaa OJ; Fuster V; Kovacic JC, 2017, 'Basic Biology of Oxidative Stress and the Cardiovascular System: Part 1 of a 3-Part Series', Journal of the American College of Cardiology, 70, pp. 196 - 211, http://dx.doi.org/10.1016/j.jacc.2017.05.034

Münzel T; Camici GG; Maack C; Bonetti NR; Fuster V; Kovacic JC, 2017, 'Impact of Oxidative Stress on the Heart and Vasculature: Part 2 of a 3-Part Series', Journal of the American College of Cardiology, 70, pp. 212 - 229, http://dx.doi.org/10.1016/j.jacc.2017.05.035

Niemann B; Rohrbach S; Miller MR; Newby DE; Fuster V; Kovacic JC, 2017, 'Oxidative Stress and Cardiovascular Risk: Obesity, Diabetes, Smoking, and Pollution: Part 3 of a 3-Part Series', Journal of the American College of Cardiology, 70, pp. 230 - 251, http://dx.doi.org/10.1016/j.jacc.2017.05.043

Johnson KW; Shameer K; Glicksberg BS; Readhead B; Sengupta PP; Björkegren JLM; Kovacic JC; Dudley JT, 2017, 'Enabling Precision Cardiology Through Multiscale Biology and Systems Medicine', JACC: Basic to Translational Science, 2, pp. 311 - 327, http://dx.doi.org/10.1016/j.jacbts.2016.11.010

Krishnamoorthy P; Vengrenyuk Y; Ueda H; Yoshimura T; Pena J; Motoyama S; Baber U; Hasan C; Kesanakurthy S; Sweeny JM; Sharma SK; Narula J; Kovacic JC; Kini AS, 2017, 'Three-dimensional volumetric assessment of coronary artery calcification in patients with stable coronary artery disease by OCT', EuroIntervention, 13, pp. 312 - 319, http://dx.doi.org/10.4244/EIJ-D-16-00139

Abgral R; Dweck MR; Trivieri MG; Robson PM; Karakatsanis N; Mani V; Padilla M; Miller M; Lala A; Sanz J; Narula J; Fuster V; Contreras J; Kovacic JC; Fayad ZA, 2017, 'Clinical Utility of Combined FDG-PET/MR to Assess Myocardial Disease', JACC: Cardiovascular Imaging, 10, pp. 594 - 597, http://dx.doi.org/10.1016/j.jcmg.2016.02.029

Bansilal S; Vedanthan R; Kovacic JC; Soto AV; Latina J; Björkegren JL; Jaslow R; Santana M; Sartori S; Giannarelli C; Mani V; Hajjar R; Schadt E; Kasarskis A; Fayad ZA; Fuster V, 2017, 'Rationale and Design of Family-Based Approach in a Minority Community Integrating Systems–Biology for Promotion of Health (FAMILIA)', American Heart Journal, 187, pp. 170 - 181, http://dx.doi.org/10.1016/j.ahj.2017.02.020

Farhan S; Baber U; Vogel B; Aquino M; Chandrasekhar J; Faggioni M; Giustino G; Kautzky-Willer A; Sweeny J; Shah S; Vijay P; Barman N; Moreno P; Kovacic J; Dangas G; Kini A; Mehran R; Sharma S, 2017, 'Impact of Diabetes Mellitus on Ischemic Events in Men and Women After Percutaneous Coronary Intervention', American Journal of Cardiology, 119, pp. 1166 - 1172, http://dx.doi.org/10.1016/j.amjcard.2016.12.035

Krishnan P; Tarricone A; Purushothaman KR; Purushothaman M; Vasquez M; Kovacic J; Baber U; Kapur V; Gujja K; Kini A; Sharma S, 2017, 'An Algorithm for the Use of Embolic Protection During Atherectomy for Femoral Popliteal Lesions', JACC: Cardiovascular Interventions, 10, pp. 403 - 410, http://dx.doi.org/10.1016/j.jcin.2016.12.014

Kovacic JC, 2017, 'Unraveling the Complex Genetics of Coronary Artery Disease', Journal of the American College of Cardiology, 69, pp. 837 - 840, http://dx.doi.org/10.1016/j.jacc.2016.12.007

Evrard SM; Lecce L; Michelis KC; Nomura-Kitabayashi A; Pandey G; Purushothaman KR; d'Escamard V; Li JR; Hadri L; Fujitani K; Moreno PR; Benard L; Rimmele P; Cohain A; Mecham B; Randolph GJ; Nabel EG; Hajjar R; Fuster V; Boehm M; Kovacic JC, 2017, 'Corrigendum: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability', Nature communications, 8, pp. 14710, http://dx.doi.org/10.1038/ncomms14710

Kini AS; Vengrenyuk Y; Shameer K; Maehara A; Purushothaman M; Yoshimura T; Matsumura M; Aquino M; Haider N; Johnson KW; Readhead B; Kidd BA; Feig JE; Krishnan P; Sweeny J; Milind M; Moreno P; Mehran R; Kovacic JC; Baber U; Dudley JT; Narula J; Sharma S, 2017, 'Intracoronary Imaging, Cholesterol Efflux, and Transcriptomes After Intensive Statin Treatment: The YELLOW II Study', Journal of the American College of Cardiology, 69, pp. 628 - 640, http://dx.doi.org/10.1016/j.jacc.2016.10.029

Kini AS; Vengrenyuk Y; Pena J; Yoshimura T; Panwar SR; Motoyama S; Kezbor S; Hasan CM; Palkhiwala S; Kovacic JC; Moreno P; Baber U; Mehran R; Narula J; Sharma SK, 2017, 'Plaque morphology predictors of side branch occlusion after provisional stenting in coronary bifurcation lesion: Results of optical coherence tomography bifurcation study (ORBID)', Catheterization and Cardiovascular Interventions, 89, pp. 259 - 268, http://dx.doi.org/10.1002/ccd.26524

Theodoropoulos K; Mennuni MG; Dangas GD; Meelu OA; Bansilal S; Baber U; Sartori S; Kovacic JC; Moreno PR; Sharma SK; Mehran R; Kini AS, 2016, 'Resistant in-stent restenosis in the drug eluting stent era', Catheterization and Cardiovascular Interventions, 88, pp. 777 - 785, http://dx.doi.org/10.1002/ccd.26559

Kiando SR; Tucker NR; Castro-Vega LJ; Katz A; D’Escamard V; Tréard C; Fraher D; Albuisson J; Kadian-Dodov D; Ye Z; Austin E; Yang ML; Hunker K; Barlassina C; Cusi D; Galan P; Empana JP; Jouven X; Gimenez-Roqueplo AP; Bruneval P; Hyun Kim ES; Olin JW; Gornik HL; Azizi M; Plouin PF; Ellinor PT; Kullo IJ; Milan DJ; Ganesh SK; Boutouyrie P; Kovacic JC; Jeunemaitre X; Bouatia-Naji N, 2016, 'PHACTR1 Is a Genetic Susceptibility Locus for Fibromuscular Dysplasia Supporting Its Complex Genetic Pattern of Inheritance', PLoS Genetics, 12, http://dx.doi.org/10.1371/journal.pgen.1006367

Franzén O; Ermel R; Cohain A; Akers NK; Di Narzo A; Talukdar HA; Foroughi-Asl H; Giambartolomei C; Fullard JF; Sukhavasi K; Köks S; Gan LM; Giannarelli C; Kovacic JC; Betsholtz C; Losic B; Michoel T; Hao K; Roussos P; Skogsberg J; Ruusalepp A; Schadt EE; Björkegren JLM, 2016, 'Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases', Science, 353, pp. 827 - 830, http://dx.doi.org/10.1126/science.aad6970

Evrard SM; Lecce L; Michelis KC; Nomura-Kitabayashi A; Pandey G; Purushothaman KR; D'Escamard V; Li JR; Hadri L; Fujitani K; Moreno PR; Benard L; Rimmele P; Cohain A; Mecham B; Randolph GJ; Nabel EG; Hajjar R; Fuster V; Boehm M; Kovacic JC, 2016, 'Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability', Nature Communications, 7, http://dx.doi.org/10.1038/ncomms11853

Jeong D; Lee M-A; Li Y; Yang DK; Kho C; Oh JG; Hong G; Lee A; Song MH; LaRocca TJ; Chen J; Liang L; Mitsuyama S; D'Escamard V; Kovacic JC; Kwak TH; Hajjar RJ; Park WJ, 2016, 'Matricellular Protein CCN5 Reverses Established Cardiac Fibrosis (vol 67, pg 1556, 2016)', JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 67, pp. 2809 - 2809, http://dx.doi.org/10.1016/j.jacc.2016.04.014

Mosley GE; Beckerman W; Kovacic JC; Kini AS; Sharma SK; Tadros RO, 2016, 'Management of complete iliofemoral artery avulsion with a hybrid technique', Journal of Vascular Surgery Cases and Innovative Techniques, 2, pp. 37 - 39, http://dx.doi.org/10.1016/j.jvsc.2016.03.002

Santini MP; Forte E; Harvey RP; Kovacic JC, 2016, 'Developmental origin and lineage plasticity of endogenous cardiac stem cells', Development (Cambridge), 143, pp. 1242 - 1258, http://dx.doi.org/10.1242/dev.111591

Vedanthan R; Bansilal S; Soto AV; Kovacic JC; Latina J; Jaslow R; Santana M; Gorga E; Kasarskis A; Hajjar R; Schadt EE; Björkegren JL; Fayad ZA; Fuster V, 2016, 'Family-Based Approaches to Cardiovascular Health Promotion', Journal of the American College of Cardiology, 67, pp. 1725 - 1737, http://dx.doi.org/10.1016/j.jacc.2016.01.036

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