By Dr Justin Guy Thomas Lees

Journal articles

Park M; Richardson A; Delic N; Nguyen K; Biazik J; Zhang R; Sprogyte L; Nureen L; Lees J; Fajardo A; Kunicki U; Watson SL; Males J; Girolamo ND, 2023, 'A Bioengineering-Regenerative Medicine Approach for Ocular Surface Reconstruction Using a Functionalized Native Cornea-Derived Bio-Scaffold', Advanced Functional Materials, 33, http://dx.doi.org/10.1002/adfm.202304856

Hooshmand K; Goldstein D; Timmins HC; Li T; Harrison M; Friedlander ML; Lewis CR; Lees JG; Moalem-Taylor G; Guennewig B; Park SB; Kwok JB, 2022, 'Polygenic risk of paclitaxel-induced peripheral neuropathy: a genome-wide association study', Journal of Translational Medicine, 20, http://dx.doi.org/10.1186/s12967-022-03754-4

Livni L; Keating BA; Fiore NT; Lees JG; Goldstein D; Moalem-Taylor G, 2022, 'Effects of combined chemotherapy and anti-programmed cell death protein 1 treatment on peripheral neuropathy and neuroinflammation in mice', Pain, 163, pp. 110 - 124, http://dx.doi.org/10.1097/j.pain.0000000000002384

Lees JG; Abdulla M; Barkl-Luke ME; Livni L; Keating BA; Hayes J; Fiore NT; Park SB; Moalem-Taylor G; Goldstein D, 2021, 'Effect of exercise on neuromuscular toxicity in oxaliplatin-treated mice', Muscle and Nerve, 64, pp. 225 - 234, http://dx.doi.org/10.1002/mus.27329

Makker PGS; Keating BA; Lees JG; Burke D; Howells J; Moalem-Taylor G, 2021, 'Electrophysiological investigation of motor axonal excitability in a mouse model of nerve constriction injury', Journal of the Peripheral Nervous System, 26, pp. 99 - 112, http://dx.doi.org/10.1111/jns.12430

Lees JG; White D; Keating BA; Barkl-Luke ME; Makker PGS; Goldstein D; Moalem-Taylor G, 2020, 'Oxaliplatin-induced haematological toxicity and splenomegaly in mice', PLoS ONE, 15, http://dx.doi.org/10.1371/journal.pone.0238164

Makker PGS; White D; Lees JG; Parmar J; Goldstein D; Park SB; Howells J; Moalem-Taylor G, 2020, 'Acute changes in nerve excitability following oxaliplatin treatment in mice', Journal of Neurophysiology, 124, pp. 232 - 244, http://dx.doi.org/10.1152/jn.00260.2020

Duffy SS; Keating BA; Perera CJ; Lees JG; Tonkin RS; Makker PGS; Carrive P; Butovsky O; Moalem-Taylor G, 2019, 'Regulatory T cells and their derived cytokine, interleukin-35, reduce pain in experimental autoimmune encephalomyelitis', Journal of Neuroscience, 39, pp. 2326 - 2346, http://dx.doi.org/10.1523/JNEUROSCI.1815-18.2019

Livni L; Lees JG; Barkl-Luke ME; Goldstein D; Moalem-Taylor G, 2019, 'Dorsal root ganglion explants derived from chemotherapy-treated mice have reduced neurite outgrowth in culture', Neuroscience Letters, 694, pp. 14 - 19, http://dx.doi.org/10.1016/j.neulet.2018.11.016

Makker PGS; Matamala JM; Park SB; Lees JG; Kiernan MC; Burke D; Moalem-Taylor G; Howells J, 2018, 'A unified model of the excitability of mouse sensory and motor axons', Journal of the Peripheral Nervous System, 23, pp. 159 - 173, http://dx.doi.org/10.1111/jns.12278

Feather CE; Lees JG; Makker PGS; Goldstein D; Kwok JB; Moalem-Taylor G; Polly P, 2018, 'Oxaliplatin induces muscle loss and muscle-specific molecular changes in Mice', Muscle and Nerve, 57, pp. 650 - 658, http://dx.doi.org/10.1002/mus.25966

Duffy SS; Lees JG; Perera CJ; Moalem-Taylor G, 2018, 'Managing neuropathic pain in multiple sclerosis: Pharmacological interventions', Medicinal Chemistry, 14, pp. 106 - 119, http://dx.doi.org/10.2174/1573406413666170906122508

Tonkin RS; Bowles C; Perera CJ; Keating BA; Makker PGS; Duffy SS; Lees JG; Tran C; Don AS; Fath T; Liu L; O'Carroll SJ; Nicholson LFB; Green CR; Gorrie C; Moalem-Taylor G, 2018, 'Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve-injured mice', Experimental Neurology, 300, pp. 1 - 12, http://dx.doi.org/10.1016/j.expneurol.2017.10.016

Howells J; Makker PGS; Lees JG; Matamala JM; Park SB; Kiernan MC; Burke D; Moalem-Taylor G, 2018, '11. Studying human neurophysiology using the mouse tail!', Clinical Neurophysiology, 129, pp. e5 - e5, http://dx.doi.org/10.1016/j.clinph.2017.12.024

Mao Y; Nguyen T; Tonkin RS; Lees JG; Warren C; O’Carroll SJ; Nicholson LFB; Green CR; Moalem-Taylor G; Gorrie CA, 2017, 'Characterisation of Peptide5 systemic administration for treating traumatic spinal cord injured rats', Experimental Brain Research, 235, pp. 3033 - 3048, http://dx.doi.org/10.1007/s00221-017-5023-3

Lees JG; Makker PGS; Tonkin RS; Abdulla M; Park SB; Goldstein D; Moalem-Taylor G, 2017, 'Immune-mediated processes implicated in chemotherapy-induced peripheral neuropathy', European Journal of Cancer, 73, pp. 22 - 29, http://dx.doi.org/10.1016/j.ejca.2016.12.006

Makker PGS; Duffy SS; Lees JG; Perera CJ; Tonkin RS; Butovsky O; Park SB; Goldstein D; Moalem-Taylor G, 2017, 'Characterisation of immune and neuroinflammatory changes associated with chemotherapy-induced peripheral neuropathy', PLoS ONE, 12, pp. e0170814, http://dx.doi.org/10.1371/journal.pone.0170814

Duffy SS; Perera CJ; Makker PGS; Lees JG; Carrive P; Moalem-Taylor G, 2016, 'Peripheral and central neuroinflammatory changes and pain behaviors in an animal model of multiple sclerosis', Frontiers in Immunology, 7, pp. 369, http://dx.doi.org/10.3389/fimmu.2016.00369

Perera CJ; Lees JG; Duffy SS; Makker PGS; Fivelman B; Apostolopoulos V; Moalem-Taylor G; Perera C, 2015, 'Effects of active immunisation with myelin basic protein and myelin-derived altered peptide ligand on pain hypersensitivity and neuroinflammation', Journal of Neuroimmunology, 286, pp. 59 - 70, http://dx.doi.org/10.1016/j.jneuroim.2015.07.004

Lees JG; Gorgani NN; Ammit AJ; McCluskey A; Robinson PJ; O'Neill GM, 2015, 'Role of dynamin in elongated cell migration in a 3D matrix', Biochimica et Biophysica Acta - Molecular Cell Research, 1853, pp. 611 - 618, http://dx.doi.org/10.1016/j.bbamcr.2014.12.008

Perera CJ; Duffy SS; Lees JG; Kim CF; Cameron B; Apostolopoulos V; Moalem-Taylor G, 2015, 'Active immunization with myelin-derived altered peptide ligand reduces mechanical pain hypersensitivity following peripheral nerve injury', Journal of Neuroinflammation, 12, http://dx.doi.org/10.1186/s12974-015-0253-4

Perera CJ; Duffy SS; Lees JG; Kim CF; Cameron B; Apostolopoulos V; Moalem-Taylor G, 2015, 'Active immunization with myelin-derived altered peptide ligand reduces mechanical pain hypersensitivity following peripheral nerve injury.', J Neuroinflammation, 12, pp. 28, http://dx.doi.org/10.1186/s12974-015-0253-4

Lees JG; Duffy SS; Perera CJ; Moalem-Taylor G; Perera C, 2015, 'Depletion of Foxp3+ regulatory T cells increases severity of mechanical allodynia and significantly alters systemic cytokine levels following peripheral nerve injury', Cytokine, 71, pp. 207 - 214, http://dx.doi.org/10.1016/j.cyto.2014.10.028

Tuch BE; Gao SY; Lees JG, 2014, 'Scaffolds for islets and stem cells differentiated into insulin-secreting cells', Frontiers in Bioscience - Landmark, 19, pp. 126 - 138, http://dx.doi.org/10.2741/4199

Duffy SS; Lees JG; Moalem-Taylor G, 2014, 'The Contribution of Immune and Glial Cell Types in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis', MULTIPLE SCLEROSIS INTERNATIONAL, 2014, http://dx.doi.org/10.1155/2014/285245

Lees JG; Duffy SS; Moalem-Taylor G, 2013, 'Immunotherapy targeting cytokines in neuropathic pain', Frontiers in Pharmacology, 4 NOV, http://dx.doi.org/10.3389/fphar.2013.00142

Lees JG; Ching YW; Adams DH; Bach CT; Samuel MS; Kee AJ; Hardeman EC; Gunning P; Cowin AJ; O'Neill GM, 2013, 'Tropomyosin regulates cell migration during skin wound healing', Journal of Investigative Dermatology, 133, pp. 1330 - 1339, http://dx.doi.org/10.1038/jid.2012.489

Zhong J; Baquiran JB; Bonakdar N; Lees J; Ching YW; Pugacheva E; Fabry B; O'Neill GM, 2012, 'NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration', PLoS ONE, 7, http://dx.doi.org/10.1371/journal.pone.0035058

Lees JG; Bach CTT; O'Neill GM, 2011, 'Interior decoration: Tropomyosin in actin dynamics and cell migration', Cell Adhesion and Migration, 5, pp. 181 - 186, http://dx.doi.org/10.4161/cam.5.2.14438

Lees JG; Bach CT; Bradbury P; Paul A; Gunning P; O'neill G, 2011, 'The actin-associating protein Tm5NM1 blocks mesenchymal motility without transition to amoeboid motility', Oncogene, 30, pp. 1241 - 1251, http://www.nature.com/onc/journal/v30/n10/full/onc2010516a.html

Gao SY; Lees JG; Wong JCY; Croll TI; George P; Cooper-White JJ; Tuch BE, 2010, 'Modeling the adhesion of human embryonic stem cells to poly(lactic-co- glycolic acid) surfaces in a 3D environment', Journal of Biomedical Materials Research - Part A, 92, pp. 683 - 692, http://dx.doi.org/10.1002/jbm.a.32401

Wong JCY; Gao SY; Lees JG; Best MB; Wang R; Tuch BE, 2010, 'Definitive endoderm derived from human embryonic stem cells highly express the integrin receptors αV and β5', Cell Adhesion and Migration, 4, pp. 39 - 45, http://dx.doi.org/10.4161/cam.4.1.10627

Sidhu K; Ryan J; Lees JG; Tuch BE, 2010, 'Derivation of a new human embryonic stem cell line, endeavour-2 and its characterization.', In vitro Cells and Development Biology, 46, pp. 269 - 275

Lees JG; Lim S; Croll T; Williams GV; Lui S; Cooper-White J; Mcquade LR; Mathiyalagan B; Tuch BE, 2007, 'Transplantation of 3D scaffolds seeded with human embryonic stem cells: biological features of surrogate tissue and teratoma-forming potential', Regenerative Medicine, 2, pp. 289 - 300

Cao Y; Croll TI; Lees JG; Tuch BE; Cooper‐White JJ, 2006, 'Scaffolds, Stem Cells, and Tissue Engineering: A Potent Combination!', ChemInform, 37, http://dx.doi.org/10.1002/chin.200610275

Khoo MLM; McQuade LR; Smith MSR; Lees JG; Sidhu KS; Tuch BE, 2006, 'Erratum: Growth and differentiation of embryoid bodies derived from human embryonic stem cells: Effect of glucose and basic fibroblast growth factor (Biology of Reproduction (2005) 73 (1147-1156) DOI: 10.1095/biolreprod.104. 036673)', Biology of Reproduction, 74, pp. 448, http://dx.doi.org/10.1095/biolreprod.105.050088

Hardikar AA; Lees JG; Sidhu KS; Colvin E; Tuch BE, 2006, 'Stem-cell therapy for diabetes cure: how close are we?', Current stem cell research & therapy, 1, pp. 425 - 436, http://dx.doi.org/10.2174/157488806778226830

Tuch BE; Lees JG, 2006, 'Conversion of embryonic stem cells into pancreatic beta cell surrogates guided by by ontogeny.', Regenerative Medicine, 1, pp. 331 - 340

Lees JG; Croll T; Lim S; Cao Y; Williams G; Mcquade LR; Mathiyalagan B; Cooper-White J; Tuch BE, 2006, 'In vitro and in vivo differentiation of hESC on PLGA scaffolds and the incidence of teratoma formation', CYTOMETRY PART A, 69A, pp. 401 - 401

Tuch BE; Hardikar AA; Lees JG; Sidhu K; Colvin EK, 2006, 'Stem-Cell therapy for diabetes cure: How close are we?', Current Stem Cell Research and Therapy, 1, pp. 231 - 238

Khoo ML; Mcquade LR; Smith MS; Lees JG; Sidhu K; Tuch BE, 2005, 'Growth and differentiation of embryoid bodies derived from human embryonic stem cells: Effect of glucose and basic fibroblast growth factor', Biology of Reproduction, 73, pp. 1147 - 1156

Cao Y; Croll T; Lees JG; Tuch BE; Cooper-White J, 2005, 'Scaffolds, stem cells, and tissue engineering: A potent combination!', Australian Journal of Chemistry, 58, pp. 691 - 703

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