Select Publications
Journal articles
, 2026, 'Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young', Molecular Cancer Therapeutics, 25, pp. 1077 - 1094, http://dx.doi.org/10.1158/1535-7163.mct-25-0736
, 2025, 'A novel TRKB-activating internal tandem duplication characterizes a new mechanism of receptor tyrosine kinase activation', Npj Precision Oncology, 9, http://dx.doi.org/10.1038/s41698-025-00928-3
, 2025, 'PDGFRA in paediatric high-grade glioma – target or distraction?', Neoplasia United States, 69, http://dx.doi.org/10.1016/j.neo.2025.101231
, 2025, 'Abstract A023-PR006: CBL mutations in pediatric solid and CNS tumours are a marker of receptor tyrosine kinase activation and a potential therapeutic target', Cancer Research, 85, pp. a023-pr006-a023-pr006, http://dx.doi.org/10.1158/1538-7445.pediatric25-a023-pr006
, 2025, 'Abstract B025: Multi-omic characterisation of the immune microenvironment in Rhabdoid Tumours', Cancer Research, 85, pp. b025 - b025, http://dx.doi.org/10.1158/1538-7445.pediatric25-b025
, 2023, 'TALLSorts: a T-cell acute lymphoblastic leukemia subtype classifier using RNA-seq expression data', Blood Advances, 7, pp. 7402 - 7406, http://dx.doi.org/10.1182/bloodadvances.2023010385
, 2023, 'Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma.', Haematologica, http://dx.doi.org/10.3324/haematol.2023.283981
, 2023, 'Biological and clinical implications of FGFR aberrations in paediatric and young adult cancers', Oncogene, 42, pp. 1875 - 1888, http://dx.doi.org/10.1038/s41388-023-02705-7
, 2023, 'Unusual PDGFRB fusion reveals novel mechanism of kinase activation in Ph-like B-ALL', Leukemia, pp. 1 - 5, http://dx.doi.org/10.1038/s41375-023-01843-x
, 2023, 'Toblerone: detecting exon deletion events in cancer using RNA-seq', F1000research, 12, http://dx.doi.org/10.12688/f1000research.129490.1
, 2023, 'Basements, Bars, and Burials: Exploring Exceptionalist Fantasy and Violence in Toni Morrison's Home', Studies in the Novel, 55, pp. 37 - 57, http://dx.doi.org/10.1353/sdn.2023.0002
, 2022, 'ALLSorts: an RNA-Seq subtype classifier for B-cell acute lymphoblastic leukemia', Blood Advances, 6, pp. 4093 - 4097, http://dx.doi.org/10.1182/bloodadvances.2021005894
, 2022, 'SFPQ-ABL1 and BCR-ABL1 use different signaling networks to drive B-cell acute lymphoblastic leukemia', Blood Advances, 6, pp. 2373 - 2387, http://dx.doi.org/10.1182/bloodadvances.2021006076
, 2022, '"It's Not My Freedom or Free": The Big Box and Toni Morrison's Meditations on Violence, Justice, and Power', MELUS, 46, pp. 14 - 36, http://dx.doi.org/10.1093/melus/mlab043
, 2020, 'Recurrent SPECC1L–NTRK fusions in pediatric sarcoma and brain tumors', Cold Spring Harbor Molecular Case Studies, 6, pp. mcs.a005710, http://dx.doi.org/10.1101/MCS.A005710
, 2020, 'Cotargeting BCL-2 and MCL-1 in high-risk B-ALL', Blood Advances, 4, pp. 2762 - 2767, http://dx.doi.org/10.1182/bloodadvances.2019001416
, 2020, 'Erratum: The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia (Blood Advances (2020) 4:5 (930-942)DOI: 10.1182/bloodadvances.2019001008)', Blood Advances, 4, pp. 1217, http://dx.doi.org/10.1182/bloodadvances.2020001859
, 2020, 'The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia', Blood Advances, 4, pp. 930 - 942, http://dx.doi.org/10.1182/bloodadvances.2019001008
, 2019, 'Targeted therapy and disease monitoring in CNTRL-FGFR1-driven leukaemia', Pediatric Blood and Cancer, 66, http://dx.doi.org/10.1002/pbc.27897
, 2018, 'Dissociation of Puberty and Adolescent Social Development in a Seasonally Breeding Species', Current Biology, 28, pp. 1116 - 1123.e2, http://dx.doi.org/10.1016/j.cub.2018.02.030
, 2017, 'The Fusion Loops of the Initial Prefusion Conformation of Herpes Simplex Virus 1 Fusion Protein Point Toward the Membrane', mBio, 8, pp. 10.1128/mbio.01268 - 10.1128/mbio.01217, http://dx.doi.org/10.1128/mbio.01268-17
, 2017, 'Dysregulation of BCL-2 family proteins by leukemia fusion genes', Journal of Biological Chemistry, 292, pp. 14325 - 14333, http://dx.doi.org/10.1074/jbc.R117.799056
, 2017, 'Functionally distinct roles for different miR-155 expression levels through contrasting effects on gene expression, in acute myeloid leukaemia', Leukemia, 31, pp. 808 - 820, http://dx.doi.org/10.1038/leu.2016.279
, 2013, 'One calcitriol dose transiently increases Helios+FoxP3+ T cells and ameliorates autoimmune demyelinating disease', JOURNAL OF NEUROIMMUNOLOGY, 263, pp. 64 - 74, http://dx.doi.org/10.1016/j.jneuroim.2013.07.016
, 2009, 'Influence of Donor Age on the Biomechanical and Biochemical Properties of Human Meniscal Allografts', The American Journal of Sports Medicine, 37, pp. 884 - 889, http://dx.doi.org/10.1177/0363546508330140
, 2006, 'Phosphorylation of the ATP-binding loop directs oncogenicity of drug-resistant BCR-ABL mutants', Proceedings of the National Academy of Sciences of the United States of America, 103, pp. 19466 - 19471, http://dx.doi.org/10.1073/pnas.0609239103
Conference Papers
, 2022, 'MULTI-PLATFORM TYROSINE KINASE PROFILING REVEALS NOVEL ACTIONABLE FGFR ABERRATIONS ACROSS PEDIATRIC AND ADOLESCENT AND YOUNG ADULT SARCOMAS', Vancouver, Canada, presented at Connective Tissue Oncology Society (CTOS) Annual Meeting 2022, Vancouver, Canada, 17 November 2022
, 2018, 'Different Classes of ABL1 Fusions Activate Different Downstream Signalling Nodes', in Blood, American Society of Hematology, pp. 2628 - 2628, http://dx.doi.org/10.1182/blood-2018-99-117844
Conference Abstracts
, 2024, 'Right oncogene, wrong tumor - CBL mutations in pediatric CNS and solid tumors', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, San Diego, Vol. 84, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2024 - 10 April 2024, http://dx.doi.org/10.1158/1538-7445.AM2024-1770
Preprints
, 2022, Toblerone: detecting exon deletion events in cancer using RNA-seq, http://dx.doi.org/10.1101/2022.10.27.514132
, ALLSorts: a RNA-Seq classifier for B-Cell Acute Lymphoblastic Leukemia, http://dx.doi.org/10.1101/2021.08.01.454393
, CBL mutations in pediatric solid and CNS tumors are a marker of receptor tyrosine kinase activation and a potential therapeutic target, http://dx.doi.org/10.64898/2025.12.02.691063
, Closing the fusion-detection gap in single-cell RNA-seq with a scalable, probe-based workflow, http://dx.doi.org/10.64898/2026.08.26.747171
, Comprehensive multi-platform tyrosine kinase profiling reveals novel actionable FGFR aberrations across pediatric and AYA sarcomas, http://dx.doi.org/10.1101/2023.07.19.548825
, Single-base precision design of CRISPR-Cas13b enables systematic silencing of oncogenic fusions, http://dx.doi.org/10.21203/rs.3.rs-1714034/v1
, Single-base precision design of CRISPR-Cas13b enables systematic silencing of oncogenic fusions, http://dx.doi.org/10.1101/2022.06.22.497105
, TALLSorts: a T-cell acute lymphoblastic leukaemia subtype classifier using RNA-seq expression data, http://dx.doi.org/10.1101/2023.04.05.535648
Other
, 2026, Data from Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young, http://dx.doi.org/10.1158/1535-7163.c.8571553
, 2026, Supplemental Figure 1. from Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young, http://dx.doi.org/10.1158/1535-7163.32872810
, 2026, Supplemental Figure 10. from Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young, http://dx.doi.org/10.1158/1535-7163.32872807
, 2026, Supplemental Figure 11. from Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young, http://dx.doi.org/10.1158/1535-7163.32872804
, 2026, Supplemental Figure 12. from Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young, http://dx.doi.org/10.1158/1535-7163.32872801
, 2026, Supplemental Figure 13. from Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young, http://dx.doi.org/10.1158/1535-7163.32872798
, 2026, Supplemental Figure 14. from Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young, http://dx.doi.org/10.1158/1535-7163.32872795
, 2026, Supplemental Figure 2. from Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young, http://dx.doi.org/10.1158/1535-7163.32872792
, 2026, Supplemental Figure 3. from Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young, http://dx.doi.org/10.1158/1535-7163.32872789
, 2026, Supplemental Figure 4. from Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young, http://dx.doi.org/10.1158/1535-7163.32872783
, 2026, Supplemental Figure 5. from Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young, http://dx.doi.org/10.1158/1535-7163.32872780
, 2026, Supplemental Figure 6. from Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young, http://dx.doi.org/10.1158/1535-7163.32872777
, 2026, Supplemental Figure 7. from Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young, http://dx.doi.org/10.1158/1535-7163.32872774