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Journal articles

Liu Y; Chen Z; Li B; Yao H; Zarka M; Welch J; Sachdev P; Bridge W; Braidy N, 2021, 'Supplementation with γ-glutamylcysteine (γ-GC) lessens oxidative stress, brain inflammation and amyloid pathology and improves spatial memory in a murine model of AD', Neurochemistry International, 144, http://dx.doi.org/10.1016/j.neuint.2020.104931

Sevindik M; Akgul H; Selamoglu Z; Braidy N, 2021, 'Antioxidant, antimicrobial and neuroprotective effects of Octaviania asterosperma in vitro', Mycology, 12, pp. 128 - 138, http://dx.doi.org/10.1080/21501203.2020.1816584

Braidy N; Alicajic H; Pow D; Smith J; Jugder BE; Brew BJ; Nicolazzo JA; Guillemin GJ, 2021, 'Potential Mechanism of Cellular Uptake of the Excitotoxin Quinolinic Acid in Primary Human Neurons', Molecular Neurobiology, 58, pp. 34 - 54, http://dx.doi.org/10.1007/s12035-020-02046-6

Tewari D; Sah AN; Bawari S; Nabavi SF; Dehpour AR; Shirooie S; Braidy N; Fiebich BL; Vacca RA; Nabavi SM, 2021, 'Role of nitric oxide in neurodegeneration: Function, regulation, and inhibition', Current Neuropharmacology, 19, pp. 114 - 126, http://dx.doi.org/10.2174/1570159X18666200429001549

Braidy N; Liu Y, 2020, 'Can nicotinamide riboside protect against cognitive impairment?', Current Opinion in Clinical Nutrition and Metabolic Care, 23, pp. 413 - 420, http://dx.doi.org/10.1097/MCO.0000000000000691

Chan LKM; Braidy N; Ng W; Xu YH; Chen J; McDonald R; Chan DKY, 2020, 'Re-pigmentation of hair after prolonged cholinesterase inhibitor therapy in a Chinese population', Australasian Journal of Dermatology, 61, pp. e417 - e420, http://dx.doi.org/10.1111/ajd.13356

Kamran SKS; Rasul A; Anwar H; Irfan S; Ullah KS; Malik SA; Razzaq A; Aziz N; Braidy N; Hussain G, 2020, 'Ferula asafoetida Linn. is effective for early functional recovery following mechanically induced insult to the sciatic nerve of a mouse model', Tropical Journal of Pharmaceutical Research, 19, pp. 1903 - 1910, http://dx.doi.org/10.4314/tjpr.v19i9.15

Iqbal G; Braidy N; Ahmed T, 2020, 'Blood-Based Biomarkers for Predictive Diagnosis of Cognitive Impairment in a Pakistani Population', Frontiers in Aging Neuroscience, 12, http://dx.doi.org/10.3389/fnagi.2020.00223

Hosseini M; Poljak A; Braidy N; Crawford J; Sachdev P, 2020, 'Blood fatty acids in Alzheimer's disease and mild cognitive impairment: A meta-analysis and systematic review', Ageing Research Reviews, 60, http://dx.doi.org/10.1016/j.arr.2020.101043

Wong MWK; Thalamuthu A; Braidy N; Mather KA; Liu Y; Ciobanu L; Baune BT; Armstrong NJ; Kwok J; Schofield P; Wright MJ; Ames D; Pickford R; Lee T; Poljak A; Sachdev PS, 2020, 'Genetic and environmental determinants of variation in the plasma lipidome of older australian twins', eLife, 9, pp. 1 - 28, http://dx.doi.org/10.7554/eLife.58954

Razzaq A; Hussain G; Rasul A; Xu J; Zhang Q; Malik SA; Anwar H; Aziz N; Braidy N; de Aguilar JLG; Wei W; Li J; Li X, 2020, 'Strychnos nux-vomica L. seed preparation promotes functional recovery and attenuates oxidative stress in a mouse model of sciatic nerve crush injury', BMC complementary medicine and therapies, 20, pp. 181, http://dx.doi.org/10.1186/s12906-020-02950-3

Wu Z; Palanimuthu D; Braidy N; Salikin NH; Egan S; Huang MLH; Richardson DR, 2020, 'Novel multifunctional iron chelators of the aroyl nicotinoyl hydrazone class that markedly enhance cellular NAD+/NADH ratios', British Journal of Pharmacology, 177, pp. 1967 - 1987, http://dx.doi.org/10.1111/bph.14963

Braidy N; Villalva MD; van Eeden S, 2020, 'Sobriety and satiety: Is NAD+ the answer?', Antioxidants, 9, http://dx.doi.org/10.3390/antiox9050425

Chiang S; Kalinowski DS; Dharmasivam M; Braidy N; Richardson DR; Huang MLH, 2020, 'The potential of the novel NAD+ supplementing agent, SNH6, as a therapeutic strategy for the treatment of Friedreich's ataxia', Pharmacological Research, 155, http://dx.doi.org/10.1016/j.phrs.2020.104680

Kaur G; Poljak A; Braidy N; Crawford JD; Lo J; Sachdev PS, 2020, 'Fluid Biomarkers and APOE Status of Early Onset Alzheimer’s Disease Variants: A Systematic Review and Meta-Analysis', Journal of Alzheimer's Disease, pp. 1 - 17, http://dx.doi.org/10.3233/jad-200052

Braidy N; Liu Y, 2020, 'NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis', Experimental Gerontology, 132, http://dx.doi.org/10.1016/j.exger.2020.110831

Ozdemir B; Selamoglu Z; Braidy N, 2020, 'Absolute Quantification of Plasma Apolipoproteins for Cardiovascular Disease Risk Prediction', , 2138, pp. 373 - 379, http://dx.doi.org/10.1007/978-1-0716-0471-7_27

Sakharkar MK; Dhillon SK; Rajamanickam K; Heng B; Braidy N; Guillemin GJ; Yang J, 2020, 'Alteration in Gene Pair Correlations in Tryptophan Metabolism as a Hallmark in Cancer Diagnosis', International Journal of Tryptophan Research, 13, http://dx.doi.org/10.1177/1178646920977013

Sevindik M; Akgul H; Selamoglu Z; Braidy N, 2020, 'Antioxidant and Antigenotoxic Potential of Infundibulicybe geotropa Mushroom Collected from Northwestern Turkey', Oxidative Medicine and Cellular Longevity, 2020, http://dx.doi.org/10.1155/2020/5620484

Dehhaghi M; Kazemi Shariat Panahi H; Braidy N; Guillemin GJ, 2020, 'Herpetosiphon Secondary Metabolites Inhibit Amyloid-β Toxicity in Human Primary Astrocytes', Journal of Alzheimer's Disease, 76, pp. 423 - 433, http://dx.doi.org/10.3233/JAD-200116

Liu Y; Chan DKY; Thalamuthu A; Wen W; Jiang J; Paradise M; Lee T; Crawford J; Wai Kin Wong M; Hua Xu Y; Poljak A; Pickford R; Sachdev PS; Braidy N; Xu Y-H, 2020, 'Plasma lipidomic biomarker analysis reveals distinct lipid changes in vascular dementia', Computational and Structural Biotechnology Journal, 18, pp. 1613 - 1624, http://dx.doi.org/10.1016/j.csbj.2020.06.001

Liu Y; Chan DKY; Crawford JD; Sachdev PS; Braidy N, 2020, 'The contribution of cerebral vascular neuropathology to mild stage of alzheimer’s dementia using the nacc database', Current Alzheimer Research, 17, pp. 1167 - 1176, http://dx.doi.org/10.2174/1567205018666210212160902

Wong MWK; Thalamuthu A; Braidy N; Mather K; Liu Y; Ciobanu L; Baune B; Armstrong N; Kwok J; Schofield P; Wright M; Ames D; Pickford R; Lee T; Poljak A; Sachdev P, 2020, 'Genetic and environmental determinants of variation in the plasma lipidome of older Australian twins', , http://dx.doi.org/10.1101/2020.05.05.075606

Ulanova M; Gloag L; Bongers A; Gooding J; Biazik J; Tilley R; Sachdev PS; Braidy N, 2020, 'Magnetic nanoparticles as MRI contrast agents for the diagnosis of Alzheimer’s disease', Alzheimer's & Dementia, 16, http://dx.doi.org/10.1002/alz.041609

Ulanova M; Poljak A; Wen W; Bongers A; Gloag L; Gooding J; Tilley R; Sachdev P; Braidy N, 2020, 'Nanoparticles as contrast agents for the diagnosis of Alzheimer’s disease: a systematic review', Nanomedicine, 15, pp. 725 - 743, http://dx.doi.org/10.2217/nnm-2019-0316

Gloag L; Mehdipour M; Ulanova M; Mariandry K; Nichol MA; Hernández-Castillo DJ; Gaudet J; Qiao R; Zhang J; Nelson M; Thierry B; Alvarez-Lemus MA; Tan TT; Gooding JJ; Braidy N; Sachdev PS; Tilley RD, 2020, 'Zero valent iron core–iron oxide shell nanoparticles as small magnetic particle imaging tracers', Chemical Communications, 56, pp. 3504 - 3507, http://dx.doi.org/10.1039/c9cc08972a

Chen Z; Jiang R; Chen M; Zheng J; Chen M; Braidy N; Liu S; Liu G; Maimaitiming Z; Shen T; Dunaief JL; Vulpe CD; Anderson GJ; Chen H, 2019, 'Multi-copper ferroxidase deficiency leads to iron accumulation and oxidative damage in astrocytes and oligodendrocytes', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-46019-9

Wong MWK; Braidy N; Pickford R; Sachdev PS; Poljak A, 2019, 'Comparison of Single Phase and Biphasic Extraction Protocols for Lipidomic Studies Using Human Plasma', Frontiers in Neurology, 10, pp. 1 - 11, http://dx.doi.org/10.3389/fneur.2019.00879

Braidy N; Zarka M; Jugder B-E; Welch J; Jayasena T; Chan DKY; Sachdev P; Bridge W, 2019, 'The Precursor to Glutathione (GSH), γ-Glutamylcysteine (GGC), Can Ameliorate Oxidative Damage and Neuroinflammation Induced by Aβ40 Oligomers in Human Astrocytes', Frontiers in Aging Neuroscience, 11, pp. 1 - 1, http://dx.doi.org/10.3389/fnagi.2019.00177

Ertilav K; Nazıroğlu M; Ataizi ZS; Braidy N, 2019, 'Selenium Enhances the Apoptotic Efficacy of Docetaxel Through Activation of TRPM2 Channel in DBTRG Glioblastoma Cells', Neurotoxicity Research, 35, pp. 797 - 808, http://dx.doi.org/10.1007/s12640-019-0009-5

Nabavi SF; Sureda A; Sanches-Silva A; Pandima Devi K; Ahmed T; Shahid M; Sobarzo-Sánchez E; Dacrema M; Daglia M; Braidy N; Vacca RA; Berindan-Neagoe I; Gulei D; Barreca D; Banach M; Nabavi SM; Dehpour AR; Shirooie S, 2019, 'Novel therapeutic strategies for stroke: The role of autophagy', Critical Reviews in Clinical Laboratory Sciences, 56, pp. 182 - 199, http://dx.doi.org/10.1080/10408363.2019.1575333

Clement J; Wong M; Poljak A; Sachdev P; Braidy N, 2019, 'The Plasma NAD⁺ Metabolome Is Dysregulated in "normal" Aging', Rejuvenation Research, 22, pp. 121 - 130, http://dx.doi.org/10.1089/rej.2018.2077

Vacca RA; Bawari S; Valenti D; Tewari D; Nabavi SF; Shirooie S; Sah AN; Volpicella M; Braidy N; Nabavi SM, 2019, 'Down syndrome: Neurobiological alterations and therapeutic targets', Neuroscience and Biobehavioral Reviews, 98, pp. 234 - 255, http://dx.doi.org/10.1016/j.neubiorev.2019.01.001

Wong MWK; Braidy N; Pickford R; Vafaee F; Crawford J; Muenchhoff J; Schofield P; Attia J; Brodaty H; Sachdev P; Poljak A, 2019, 'Plasma lipidome variation during the second half of the human lifespan is associated with age and sex but minimally with BMI', PLoS ONE, 14, pp. e0214141, http://dx.doi.org/10.1371/journal.pone.0214141

Farzaei MH; Bahramsoltani R; Abbasabadi Z; Braidy N; Nabavi SM, 2019, 'Role of green tea catechins in prevention of age-related cognitive decline: Pharmacological targets and clinical perspective', Journal of Cellular Physiology, 234, pp. 2447 - 2459, http://dx.doi.org/10.1002/jcp.27289

Dehhaghi M; Tan V; Heng B; Braidy N; Mohammadipanah F; Guillemin GJ, 2019, 'Neuroprotective Effect of Myxobacterial Extracts on Quinolinic Acid-Induced Toxicity in Primary Human Neurons', Neurotoxicity Research, 35, pp. 281 - 290, http://dx.doi.org/10.1007/s12640-018-9945-8

Braidy N; Berg J; Clement J; Khorshidi F; Poljak A; Jayasena T; Grant R; Sachdev PS, 2019, 'Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes', Antioxidants and Redox Signaling, 30, pp. 251 - 294, http://dx.doi.org/10.1089/ars.2017.7269

Wong MWK; Braidy N; Crawford J; Pickford R; Song F; Mather KA; Attia J; Brodaty H; Sachdev P; Poljak A, 2019, 'APOE Genotype Differentially Modulates Plasma Lipids in Healthy Older Individuals, with Relevance to Brain Health', Journal of Alzheimer's Disease, 72, pp. 703 - 716, http://dx.doi.org/10.3233/JAD-190524

Öztürk Y; Günaydın C; Yalçın F; Nazıroğlu M; Braidy N, 2019, 'Resveratrol enhances apoptotic and oxidant effects of paclitaxel through TRPM2 channel activation in DBTRG glioblastoma cells', Oxidative Medicine and Cellular Longevity, 2019, http://dx.doi.org/10.1155/2019/4619865

Nabavi SF; Sureda A; Dehpour AR; Shirooie S; Silva AS; Devi KP; Ahmed T; Ishaq N; Hashim R; Sobarzo-Sánchez E; Daglia M; Braidy N; Volpicella M; Vacca RA; Nabavi SM, 2018, 'Regulation of autophagy by polyphenols: Paving the road for treatment of neurodegeneration', Biotechnology Advances, 36, pp. 1768 - 1778, http://dx.doi.org/10.1016/j.biotechadv.2017.12.001

Amiri M; Braidy N; Aminzadeh M, 2018, 'Protective Effects of Fibroblast Growth Factor 21 Against Amyloid-Beta1–42-Induced Toxicity in SH-SY5Y Cells', Neurotoxicity Research, 34, pp. 574 - 583, http://dx.doi.org/10.1007/s12640-018-9914-2

BRAIDY N, 2018, 'Intravenous NAD+ effectively increased the NAD metabolome, reduced oxidative stress and inflammation, and increased expression of longevity genes safely in elderly humans', Journal of Cellular Neuroscience and Oxidative Stress, 10, pp. 779 - 779, http://dx.doi.org/10.37212/jcnos.610084

Seyedsadjadi N; Berg J; Bilgin AA; Braidy N; Salonikas C; Grant R, 2018, 'High protein intake is associated with low plasma NAD+ levels in a healthy human cohort', PLoS ONE, 13, pp. e0201968, http://dx.doi.org/10.1371/journal.pone.0201968

Liu Y; Braidy N; Poljak A; Chan DK; Sachdev PS, 2018, 'Cerebral small vessel disease and the risk of Alzheimer's disease: A systematic review', Ageing Research Reviews, http://dx.doi.org/10.1016/j.arr.2018.06.002

2018, 'Therapeutic relevance of ozone therapy in degenerative diseases: Focus on diabetes and spinal pain', Journal of Cellular Physiology, 233, pp. 2705 - 2714, http://dx.doi.org/10.1002/jcp.26044

Braidy N; Grant R; Sachdev PS, 2018, 'Nicotinamide adenine dinucleotide and its related precursors for the treatment of Alzheimer's disease', Current Opinion in Psychiatry, 31, pp. 160 - 166, http://dx.doi.org/10.1097/yco.0000000000000394

Nabavi SM; Nabavi SF; Sureda A; Caprioli G; Iannarelli R; Sokeng AJT; Braidy N; Khanjani S; Moghaddam AH; Atanasov AG; Daglia M; Maggi F, 2018, 'The water extract of tutsan (Hypericum androsaemum L.) red berries exerts antidepressive-like effects and in vivo antioxidant activity in a mouse model of post-stroke depression', Biomedicine and Pharmacotherapy, 99, pp. 290 - 298, http://dx.doi.org/10.1016/j.biopha.2018.01.073

Mello FD; Braidy N; Marçal H; Guillemin G; Nabavi SM; Neilan BA, 2018, 'Mechanisms and Effects Posed by Neurotoxic Products of Cyanobacteria/Microbial Eukaryotes/Dinoflagellates in Algae Blooms: a Review', Neurotoxicity Research, 33, pp. 153 - 167, http://dx.doi.org/10.1007/s12640-017-9780-3

Valenti D; Braidy N; De Rasmo D; Signorile A; Rossi L; Atanasov AG; Volpicella M; Henrion-Caude A; Nabavi SM; Vacca RA, 2018, 'Mitochondria as pharmacological targets in Down syndrome', Free Radical Biology and Medicine, 114, pp. 69 - 83, http://dx.doi.org/10.1016/j.freeradbiomed.2017.08.014

Palanimuthu D; Wu Z; Jansson PJ; Braidy N; Bernhardt PV; Richardson DR; Kalinowski DS, 2018, 'Novel chelators based on adamantane-derived semicarbazones and hydrazones that target multiple hallmarks of Alzheimer's disease', Dalton Transactions, 47, pp. 7190 - 7205, http://dx.doi.org/10.1039/c8dt01099d


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