By Dr Neil Alexander Youngson

Journal articles

Youngson NA; Vickaryous N; Van Der Horst A; Epp T; Harten S; Fleming JS; Khanna KK; De Kretser DM; Whitelaw E, 2011, 'A missense mutation in the transcription factor Foxo3a causes teratomas and oocyte abnormalities in mice', Mammalian Genome, 22, pp. 235 - 248, http://dx.doi.org/10.1007/s00335-011-9317-7

Youngson NA; Whitelaw E, 2011, 'The effects of acquired paternal obesity on the next generation', Asian Journal of Andrology, 13, pp. 195 - 196, http://dx.doi.org/10.1038/aja.2010.163

Youngson NA; Chong S; Whitelaw E, 2011, 'Gene silencing is an ancient means of producing multiple phenotypes from the same genotype: Common mechanisms and functions in epigenetic processes can be seen throughout all life forms', BioEssays, 33, pp. 95 - 99, http://dx.doi.org/10.1002/bies.201000122

Tierling S; Gasparoni G; Youngson N; Paulsen M, 2009, 'The Begain gene marks the centromeric boundary of the imprinted region on mouse chromosome 12', Mammalian Genome, 20, pp. 699 - 710, http://dx.doi.org/10.1007/s00335-009-9205-6

Li X; Ito M; Zhou F; Youngson N; Zuo X; Leder P; Ferguson-Smith AC, 2008, 'A Maternal-Zygotic Effect Gene, Zfp57, Maintains Both Maternal and Paternal Imprints', Developmental Cell, 15, pp. 547 - 557, http://dx.doi.org/10.1016/j.devcel.2008.08.014

Youngson NA; Whitelaw E, 2008, 'Transgenerational epigenetic effects', Annual Review of Genomics and Human Genetics, 9, pp. 233 - 257, http://dx.doi.org/10.1146/annurev.genom.9.081307.164445

Chong S; Youngson NA; Whitelaw E, 2007, 'Heritable germline epimutation is not the same as transgenerational epigenetic inheritance [5]', Nature Genetics, 39, pp. 574 - 575, http://dx.doi.org/10.1038/ng0507-574

Chong S; Vickaryous N; Ashe A; Zamudio N; Youngson N; Hemley S; Stopka T; Skoultchi A; Matthews J; Scott HS; De Kretser D; O'Bryan M; Blewitt M; Whitelaw E, 2007, 'Modifiers of epigenetic reprogramming show paternal effects in the mouse', Nature Genetics, 39, pp. 614 - 622, http://dx.doi.org/10.1038/ng2031

Youngson NA; Kocialkowski S; Peel N; Ferguson-Smith AC, 2005, 'A small family of sushi-class retrotransposon-derived genes in mammals and their relation to genomic imprinting', Journal of Molecular Evolution, 61, pp. 481 - 490, http://dx.doi.org/10.1007/s00239-004-0332-0

Seitz H; Royo H; Lin SP; Youngson N; Ferguson-Smith AC; Cavaillé J, 2004, 'Imprinted small RNA genes', Biological Chemistry, 385, pp. 905 - 911, http://dx.doi.org/10.1515/BC.2004.118

Ferguson-Smith AC; Lin SP; Youngson N, 2004, 'Regulation of Gene Activity and Repression: A Consideration of Unifying Themes', Current Topics in Developmental Biology, 60, pp. 197 - 213, http://dx.doi.org/10.1016/S0070-2153(04)60006-8

Cavaille J; Seitz H; Royo HLN; Lin * S-P; Youngson * N; Ferguson-Smith * AC, 2004, 'Imprinted microRNA genes at the mouse Dlk1-GTl2 domain.', GBM Annual Fall meeting M�nster 2004, 2004, http://dx.doi.org/10.1240/sav_gbm_2004_h_000626

Lin SP; Youngson N; Takada S; Seitz H; Reik W; Paulsen M; Cavaille J; Ferguson-Smith AC, 2003, 'Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12', Nature Genetics, 35, pp. 97 - 102, http://dx.doi.org/10.1038/ng1233

Seitz H; Youngson N; Lin SP; Dalbert S; Paulsen M; Bachellerie JP; Ferguson-Smith AC; Cavaillé J, 2003, 'Imprinted microRNA genes transcribed antisense to a reciprocally imprinted retrotransposon-like gene', Nature Genetics, 34, pp. 261 - 262, http://dx.doi.org/10.1038/ng1171

Ferguson-Smith A; Lin SP; Tsai CE; Youngson N; Tevendale M, 2003, 'Genomic imprinting - Insights from studies in mice', Seminars in Cell and Developmental Biology, 14, pp. 43 - 49, http://dx.doi.org/10.1016/S1084-9521(02)00171-4

Paulsen M; Takada S; Youngson NA; Benchaib M; Charlier C; Segers K; Georges M; Ferguson-Smith AC, 2001, 'Comparative sequence analysis of the imprinted Dlk1-Gtl2 locus in three mammalian species reveals highly conserved genomic elements and refines comparison with the Igf2-H19 region', Genome Research, 11, pp. 2085 - 2094, http://dx.doi.org/10.1101/gr.206901

Meiklejohn DJ; Riches Z; Youngson N; Vicker MA, 2000, 'The contribution of factor VII gene polymorphisms to longevity in Scottish nonagenarians', Thrombosis and Haemostasis, 83, pp. 519, http://dx.doi.org/10.1055/s-0037-1613854

Conference Papers

Youngson N; Oey H; Whitelaw E, 2011, 'PATERNAL EFFECTS IN MICE CAUSED BY DICER OR DNMT1 HAPLOINSUFFICIENCY ARE ASSOCIATED WITH CHANGES IN SPERMATOZOAL MIRNA EXPRESSION PROFILE', in JOURNAL OF ANDROLOGY, AMER SOC ANDROLOGY, INC, CANADA, Hyatt Regency Montreal, Montreal, pp. 94 - 95, presented at 36th Annual Meeting of Genes and Harmones - State-of-the-Art Reproductive and Sexual Development, CANADA, Hyatt Regency Montreal, Montreal, 02 April 2011 - 05 April 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000287549800146&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Youngson NA; Kocialowski S; Peel N; Ferguson-Smith AC, 2004, 'A small family of LTR retrotransposon-derived genes in mammals and their relation to genomic imprinting', in GENETICAL RESEARCH, CAMBRIDGE UNIV PRESS, ENGLAND, Univ Coll London, Inst Child Hlth, London, pp. 236 - 236, presented at 15th Genetics-Societys Mammalian Genetics and Development Workshop, ENGLAND, Univ Coll London, Inst Child Hlth, London, 22 November 2004 - 23 November 2004, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000235431000018&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Meiklejohn DJ; Riches Z; Youngson N; Vickers M, 1999, 'The contribution of factor VII (FVII) gene polymorphisms to longevity', in THROMBOSIS AND HAEMOSTASIS, F K SCHATTAUER VERLAG GMBH, pp. 187 - 187, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000085665900586&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Meiklejohn DJ; Riches Z; Youngson N; Vickers M, 1999, 'The contribution of factor VII (FVII) gene polymorphisms to longevity.', in BRITISH JOURNAL OF HAEMATOLOGY, BLACKWELL SCIENCE LTD, pp. 38 - 38, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000080134600050&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts

Assante G; Chandrasekaran S; Ng S; Tourna A; Chung C; Isse K; Banks J; Soffientini U; Filippi C; Dhawan A; Liu M; Rozen S; Hoare M; Campbell P; Ballard W; Turner N; Morris M; Chokshi S; Youngson N, 2022, 'Acetyl coenzyme A metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, Vol. 37, pp. 24 - 25, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000852585700049&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Stamouli M; Adelmeijer J; Rivera S; O'Reilly K; Palma E; Youngson N; Bernal W; Chokshi S; Lisman T; Patel VC, 2022, 'CIRCULATING MARKERS OF NEUTROPHIL EXTRACELLULAR TRAPS ARE ASSOCIATED WITH EXCESSIVE COAGULATION ACTIVATION IN DECOMPENSATED CIRRHOSIS AND ACUTE-ON-CHRONIC LIVER FAILURE', in GUT, BMJ PUBLISHING GROUP, Vol. 71, pp. A51 - A52, http://dx.doi.org/10.1136/gutjnl-2022-BASL.77

Stamouli M; Adelmeijer J; Huskens D; Rivera S; O'Reilly K; Palma E; Youngson N; Bernal W; Chokshi S; Roest M; Lisman T; Patel V, 2022, 'Circulating cell-free DNA levels increment with worsening cirrhosis severity and associate with platelet exhaustion and mortality', in JOURNAL OF HEPATOLOGY, ELSEVIER, Vol. 77, pp. S911 - S911, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000826275104351&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Illingworth M; Zen Y; Nayagam J; Joshi D; Urbani L; Youngson N; Heaton N; Khorsandi SE, 2022, 'Ribosomal protein encoding genes: potential drivers of primary sclerosing cholangitis associated cholangiocarcinoma', in JOURNAL OF HEPATOLOGY, ELSEVIER, Vol. 77, pp. S650 - S651, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000826275103254&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Assante G; Tourna A; Chokshi S; Turner N; Ballard JWO; Morris M; Youngson N, 2021, 'Acetyl-CoA metabolism drives epigenome change in liver steatosis leading to widespread abnormal transcription, DNA damage and promotion of hepatocarcinogenetic pathways', in JOURNAL OF HEPATOLOGY, ELSEVIER, Vol. 75, pp. S264 - S265, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000667753800109&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Tourna A; Stamouli M; Arefaine B; Baselli GA; Valenti L; Chokshi S; Youngson N; Patel VC, 2021, 'Methylation state of circulating cell-free DNA as a prognostic marker for early to late stage chronic liver disease and acute on chronic liver failure', in JOURNAL OF HEPATOLOGY, ELSEVIER, Vol. 75, pp. S333 - S334, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000667753800226&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Yu J; Morris MJ; Youngson NA, 2019, 'Do exercise and NMN provide synergistic benefits in obese mice?', in Obesity Research & Clinical Practice, Elsevier BV, Vol. 13, pp. 299 - 299, http://dx.doi.org/10.1016/j.orcp.2018.11.182

Youngson NA; Lecomte V; Maloney CA; Morris KV; Morris MJ, 2017, 'RNA-SEQUENCING TO DISCOVER NOVEL LONG-NON CODING RNA (LNCRNA) ASSOCIATED WITH OBESITY IN RAT LIVER', in JOURNAL OF GENE MEDICINE, WILEY, AUSTRALIA, Univ Technol Sydney, Sydney, Vol. 20, presented at Joint 10th Annual Scientific Meeting of the Australian-Gene-and-Cell-Therapy-Society (AGCTS) and Australasian-Society-for-Stem-Cell-Research (ASSCR), AUSTRALIA, Univ Technol Sydney, Sydney, 24 May 2017 - 26 May 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000426528300089&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Gokarn R; Solon-Biet S; Youngson N; Cogger V; McMahon AC; Morris M; Simpson S; Le Couteur D, 2015, 'Low Dietary Protein to Carbohydrate Ratios Are Linked With Longer Telomere Lengths in Mice', in GERONTOLOGIST, OXFORD UNIV PRESS INC, Vol. 55, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000374222704652&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Castino M; Youngson N; Baker-Andresen D; Ratnu V; Bredy T; Clemens K, 2015, 'Transcriptional and epigenetic factors underlying the extinction of nicotine-seeking behaviour in the rat', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, AUSTRALIA, Cairns, Vol. 134, pp. 349 - 349, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, AUSTRALIA, Cairns, 23 August 2015 - 27 August 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300896&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Uddin GM; Youngson N; Sinclair DA; Morris M, 2014, 'Impaired blood glucose clearance and mitochondrial function induced by high fat diet is improved by exercise and an ‘exercise mimetic’', in Obesity Research & Clinical Practice, Elsevier BV, Vol. 8, pp. 108 - 108, http://dx.doi.org/10.1016/j.orcp.2014.10.195

Maloney CA; Lecomte V; Youngson NA; Morris MJ, (ed.), 2013, 'Effects of paternal obesity on F1 female offspring', in Obesity Research & Clinical Practice, Elsevier, Merlbourne, Vol. 7, presented at Australian and New Zeeland Obesity Society (ANZOS) meeting, Merlbourne, 17 October 2013 - 19 October 2013, http://dx.doi.org/10.1016/j.orcp.2013.12.625

Working Papers

Towarnicki S; Youngson NA; Corley S; St John J; Turner N; Morris M; Ballard B, 2020, Ancestral dietary change alters development of Drosophila larvae through MAPK signalling, Cold Spring Harbor, http://dx.doi.org10.1101/2020.10.07.327478, https://www.biorxiv.org/content/10.1101/2020.10.07.327478v1

Youngson NA; Castino MR; Stuart A; Kershaw KA; Holmes NM; Waters PD; Morris KV; Clemens KJ, 2019, A natural antisense to brain-derived neurotrophic factor impairs extinction of drug seeking, Cold Spring Harbor Laboratory, http://dx.doi.org10.1101/851949

Bertoldo MJ; Listijono DR; Ho W-HJ; Riepsamen AH; Jin XL; Selesniemi K; Goss DM; Mahbub S; Campbell JM; Habibalahi A; Loh W-GN; Youngson NA; Maniam J; Wong ASA; Richani D; Li C; Zhao Y; Marinova M; Kim L-J; Lau L; Wu RM; Mikolaizak AS; Araki T; Le Couteur DG; Turner N; Morris MJ; Walters KA; Goldys E; O’Neill C; Gilchrist RB; Sinclair DA; Homer HA; Wu LE, 2019, NAD+ repletion rescues female fertility during reproductive ageing, Cold Spring Harbor Laboratory, http://dx.doi.org10.1101/721985

Preprints

Oberin R; Petautschnig S; Tsai T; Jarred EG; Qu Z; Youngson NA; Bildsoe H; Truong TT; Fernando D; van den Buuse M; Gardner DK; Sims NA; Adelson DL; Western PS, 2022, Loss of EED in the oocyte causes initial fetal growth restriction followed by placental hyperplasia and offspring overgrowth, , http://dx.doi.org/10.1101/2022.08.08.503175

Assante G; Chandrasekaran S; Ng S; Tourna A; Chung C; Isse K; Filippi C; Dhawan A; Liu M; Rozen S; Hoare M; Campbell P; Ballard W; Turner N; Morris M; Chokshi S; Youngson N, 2021, Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease, , http://dx.doi.org/10.1101/2021.07.22.453333

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