Researcher

Dr Tao Liu

Field of Research (FoR)

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Biography

Qualifications: BMed, MMed, PhD

Research Interests:

  1. Transcriptional modulation of oncogene and tumour suppressor gene expression by histone deacetylases, histone demethylases, histone methyltransferases, BET bromodomain proteins and super-enhancers.
  2. The roles of histone deacetylases, histone demethylases, histone methyltransferases, long noncoding RNAs, BET bromodomain proteins, CDK7, RNA methyltransferases and demethylases in the initiation...view more

Qualifications: BMed, MMed, PhD

Research Interests:

  1. Transcriptional modulation of oncogene and tumour suppressor gene expression by histone deacetylases, histone demethylases, histone methyltransferases, BET bromodomain proteins and super-enhancers.
  2. The roles of histone deacetylases, histone demethylases, histone methyltransferases, long noncoding RNAs, BET bromodomain proteins, CDK7, RNA methyltransferases and demethylases in the initiation and progression of cancer.
  3. The anticancer efficacy of histone deacetylase inhibitors, histone methyltransferase inhibitors, bromodomain inhibitors, CDK7 inhibitors and methylation inhibitors in cancer cell lines and animal models.
  4. Identification of the mechanisms important for the stability and/or degradation of Myc oncoproteins, the most commonly de-regulated oncoprotein in human cancers.
  5. Long noncoding RNAs as critical modulators of chromatin function and gene expression.
  6. Discovery of novel long noncoding RNA inhibitors for the therapy of cancer.

 Broad Research Areas:

  1. Molecular and cellular biology
  2. Chromatin modification
  3. Gene transcription & Genomics
  4. Long noncoding RNA
  5. RNA methylation
  6. Genomics and epigenetics
  7. Drug discovery
  8. Experimental cancer therapy

Society Memberships & Professional Activities:

  1. Advisory Board member, international Advances in Neruoblastoma Research Association
  2. Member,  American Association for Cancer Research
  3. Associate Editor, Frontiers in Oncology
  4. Associate Editor, Frontiers in Genetics
  5. Editor, International Journal of Clinical and Experimental Medicine
  6. Editor, World Journal of Biological Chemistry
  7. Editor, Epigenetics & Genomics

Weblink: http://www.ccia.org.au/index.cfm?pageCall=staffMember&staffID=87866 


My Grants

National Institutes of Health USA

National Health & Medical Research Council

Cancer Council NSW


My Qualifications

BMed, MMed, PhD


My Research Supervision


Supervision keywords


Areas of supervision

ILP, Honours, MAsters, PhD


Currently supervising

PhD and Honours students

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Location

Children's Cancer Institute
Lowy Cancer Research Centre, UNSW Australia
PO Box 81 Randwick 2031 Australia
http://ccia.org.au

Contact

61 2 9385 1935
61 2 9662 6583