Select Publications

Journal articles

Petty A; Glass LJ; Rothmond DA; Purves-Tyson T; Sweeney A; Kondo Y; Kubo S; Matsumoto M; Weickert CS, 2022, 'Increased levels of a pro-inflammatory IgG receptor in the midbrain of people with schizophrenia', Journal of Neuroinflammation, vol. 19,

O'Donnell M; Teasdale S; Chua X-Y; Hardman J; Wu N; Curtis J; Samaras K; Bolton P; Morris M; Shannon-Weickert C; Purves-Tyson T; El-Assaad F; Jiang X; Hold G; El-Omar E, 2022, 'The role of the microbiome in the metabolic health of people with schizophrenia and related psychoses: cross-sectional and pre-post lifestyle intervention analyses', Pathogens

Zhu Y; Owens SJ; Murphy CE; Ajulu K; Rothmond D; Purves-Tyson T; Middleton F; Webster MJ; Weickert CS, 2022, 'Inflammation-related transcripts define “high” and “low” subgroups of individuals with schizophrenia and bipolar disorder in the midbrain', Brain, Behavior, and Immunity, vol. 105, pp. 149 - 159,

Brown AM; Conn I; Boerrigter D; Shannon Weickert C; Purves-Tyson TD, 2022, 'Maternal immune activation with high molecular weight poly(I:C) in Wistar rats leads to elevated immune cell chemoattractants', Journal of Neuroimmunology, vol. 364,

Brown SJ; Brown AM; Purves-Tyson TD; Huang XF; Shannon Weickert C; Newell KA, 2022, 'Alterations in the kynurenine pathway and excitatory amino acid transporter-2 in depression with and without psychosis: Evidence of a potential astrocyte pathology', Journal of Psychiatric Research, vol. 147, pp. 203 - 211,

Rahman T; Purves-Tyson T; Geddes AE; Huang XF; Newell KA; Weickert CS, 2022, 'N-Methyl-D-Aspartate receptor and inflammation in dorsolateral prefrontal cortex in schizophrenia', Schizophrenia Research, vol. 240, pp. 61 - 70,

Purves-Tyson TD; Brown AM; Weissleder C; Rothmond DA; Shannon Weickert C, 2021, 'Reductions in midbrain GABAergic and dopamine neuron markers are linked in schizophrenia', Molecular Brain, vol. 14, pp. 96,

Purves-Tyson TD; Weber-Stadlbauer U; Richetto J; Rothmond DA; Labouesse MA; Polesel M; Robinson K; Shannon Weickert C; Meyer U, 2021, 'Increased levels of midbrain immune-related transcripts in schizophrenia and in murine offspring after maternal immune activation', Molecular Psychiatry, vol. 26, pp. 849 - 863,

Ji E; Weickert CS; Purves-Tyson T; White C; Handelsman DJ; Desai R; O'Donnell M; Liu D; Galletly C; Lenroot R; Weickert TW, 2021, 'Cortisol-dehydroepiandrosterone ratios are inversely associated with hippocampal and prefrontal brain volume in schizophrenia', Psychoneuroendocrinology, vol. 123,

Rahman T; Weickert CS; Harms L; Meehan C; Schall U; Todd J; Hodgson DM; Michie PT; Purves-Tyson T, 2020, 'Effect of Immune Activation during Early Gestation or Late Gestation on Inhibitory Markers in Adult Male Rats', Scientific Reports, vol. 10, pp. 1982,

Purves-Tyson TD; Robinson K; Brown AM; Boerrigter D; Cai HQ; Weissleder C; Owens SJ; Rothmond DA; Shannon Weickert C, 2020, 'Increased Macrophages and C1qA, C3, C4 Transcripts in the Midbrain of People With Schizophrenia', Frontiers in Immunology, vol. 11,

Purves-Tyson T; Cai H; Boerrigter D; Rothmond D; Shannon Weickert C, 2020, 'O11.2. ELEVATION OF MACROPHAGE-RELATED TRANSCRIPTS IN THE MIDBRAIN IN SCHIZOPHRENIA', Schizophrenia Bulletin, vol. 46, pp. S27 - S28,

Owens SJ; Purves-Tyson TD; Webster MJ; Shannon Weickert C, 2019, 'Evidence for enhanced androgen action in the prefrontal cortex of people with bipolar disorder but not schizophrenia or major depressive disorder', Psychiatry Research, vol. 280, pp. 112503,

Owens SJ; Weickert TW; Purves-Tyson TD; Ji E; White C; Galletly C; Liu D; O'Donnell M; Shannon Weickert C, 2019, 'Sex-Specific Associations of Androgen Receptor CAG Trinucleotide Repeat Length and of Raloxifene Treatment with Testosterone Levels and Perceived Stress in Schizophrenia.', Mol Neuropsychiatry, vol. 5, pp. 28 - 41,


Purves-Tyson T; Rothmond D; Weickert CS, 2018, '40.1 INFLAMMATORY CYTOKINES ARE ELEVATED IN THE MIDBRAIN IN SCHIZOPHRENIA', Schizophrenia Bulletin, vol. 44, pp. S64 - S64,

Owens SJ; Murphy CE; Purves-Tyson TD; Weickert TW; Shannon Weickert C, 2018, 'Considering the role of adolescent sex steroids in schizophrenia', Journal of Neuroendocrinology, vol. 30,

Rahman T; Zavitsanou K; Purves-Tyson T; Harms LR; Meehan C; Schall U; Todd J; Hodgson DM; Michie PT; Weickert CS, 2017, 'Effects of immune activation during early or late gestation on N-Methyl-D-Aspartate receptor measures in adult rat offspring', Frontiers in Psychiatry, vol. 8,

Newton-Mann E; Finney C; Purves-Tyson T; Gogos A, 2017, 'Estrogen receptors: Mechanism of action and relevance to schizophrenia', Current Psychiatry Reviews, vol. 13, pp. 55 - 64,

Purves-Tyson TD; Owens SJ; Rothmond DA; Halliday GM; Double KL; Stevens J; McCrossin T; Shannon Weickert C, 2017, 'Putative presynaptic dopamine dysregulation in schizophrenia is supported by molecular evidence from post-mortem human midbrain', Translational Psychiatry, vol. 7,

Purves-Tyson TD; Allen K; Fung S; Rothmond D; Noble PL; Handelsman DJ; Shannon Weickert C, 2015, 'Adolescent testosterone influences BDNF and TrkB mRNA and neurotrophin-interneuron marker relationships in mammalian frontal cortex', Schizophrenia Research, vol. 168, pp. 661 - 670,

Allen KM; Purves-Tyson TD; Shannon Weickert C, 2015, 'Reproductive hormones and schizophrenia', Schizophrenia Research, vol. 168, pp. 601 - 602,

Morris RW; Purves-Tyson TD; Weickert CS; Rothmond D; Lenroot R; Weickert TW, 2015, 'Testosterone and reward prediction-errors in healthy men and men with schizophrenia', Schizophrenia Research, vol. 168, pp. 649 - 660,

Purves-Tyson TD; Boerrigter D; Allen K; Zavitsanou K; Karl T; Djunaidi V; Double KL; Desai R; Handelsman DJ; Weickert CS, 2015, 'Testosterone attenuates and the selective estrogen receptor modulator, raloxifene, potentiates amphetamine-induced locomotion in male rats', Hormones and Behavior, vol. 70, pp. 73 - 84,

Allen KM; Purves-Tyson TD; Fung SJ; Shannon Weickert C, 2015, 'The effect of adolescent testosterone on hippocampal BDNF and TrkB mRNA expression: Relationship with cell proliferation', BMC Neuroscience, vol. 16,

Purves-Tyson TD; Owens SJ; Double KL; Desai R; Handelsman DJ; Weickert CS, 2014, 'Testosterone induces molecular changes in dopamine signaling pathway molecules in the adolescent male rat nigrostriatal pathway', PLoS ONE, vol. 9,

Zavitsanou K; Lim CK; Purves-Tyson T; Karl T; Kassiou M; Banister SD; Guillemin GJ; Weickert CS, 2014, 'Effect of maternal immune activation on the kynurenine pathway in preadolescent rat offspring and on MK801-induced hyperlocomotion in adulthood: Amelioration by COX-2 inhibition', Brain, Behavior, and Immunity, vol. 41, pp. 173 - 181,

Sinclair D; Purves-Tyson TD; Allen KM; Weickert CS, 2014, 'Impacts of stress and sex hormones on dopamine neurotransmission in the adolescent brain', Psychopharmacology, vol. 231, pp. 1581 - 1599,

Purves-Tyson TD; Handelsman D; Double KL; Bustamante S; owens SJ; Shannon Weickert C, 2012, 'Testosterone regulation of sex steroid-related mRNAs and dopamine-related mRNAs in adolescent male rat substantia nigra', BMC Neuroscience, vol. 13, pp. 95,

Lee GL; Purves-Tyson TD, 2009, 'P5.6 Neuritin message is increased by testosterone in cultured rat pelvic autonomic neurons but is unchanged in pelvic ganglia in experimental diabetes', Autonomic Neuroscience, vol. 149, pp. 104 - 105,

Purves-Tyson TD; Arshi M; Handelsman D; Cheng Y; Keast JR, 2007, 'Androgen and estrogen receptor-mediated mechanisms of testosterone action in male rat pelvic autonomic ganglia', Neuroscience, vol. 148, pp. 92 - 104,

Fernyhough P; Smith DR; Schapansky J; Van Der Ploeg R; Gardiner NJ; Tweed CW; Kontos A; Freeman L; Purves-Tyson TD; Glazner GW, 2005, 'Activation of nuclear factor-κB via endogenous tumor necrosis factor α regulates survival of axotomized adult sensory neurons', Journal of Neuroscience, vol. 25, pp. 1682 - 1690,

Purves-Tyson TD; Keast JR, 2004, 'Rapid actions of estradiol on cyclic amp response-element binding protein phosphorylation in dorsal root ganglion neurons', Neuroscience, vol. 129, pp. 629 - 637,

Price SA; Hounsom L; Purves-Tyson TD; Fernyhough P; Tomlinson DR, 2003, 'Activation of JNK in Sensory Neurons Protects against Sensory Neuron Cell Death in Diabetes and on Exposure to Glucose/Oxidative Stress in Vitro', Annals of the New York Academy of Sciences, vol. 1010, pp. 95 - 99,

Tomlinson DR; Purves T; Fernyhough P, 2002, 'Diabetic neuropathies', BRITISH JOURNAL OF PHARMACOLOGY, vol. 136,

Sayers NM; Purves TD; Fernyhough P, 2002, 'Neurofilament phosphorylation in sensory neurons in the streptozotocin (STZ)-Diabetic rat; Effect of neurotrophin-3 therapy', DIABETES, vol. 51, pp. A195 - A195,

Purves TD; Tomlinson DR, 2002, 'Are mitogen-activated protein kinases glucose transducers for diabetic neuropathies?', International Review of Neurobiology, vol. 50, pp. 83 - 114,

Purves TD; Tomlinson DR, 2002, 'Diminished transcription factor survival signals in dorsal root ganglia in rats with streptozotocin-induced diabetes', Annals of the New York Academy of Sciences, vol. 973, pp. 472 - 476,

Purves T; Middlemas A; Agthong S; Jude EB; Boulton AJM; Fernyhough P; Tomlinson DR, 2001, 'A role for mitogen-activated protein kinases in the etiology of diabetic neuropathy', FASEB Journal, vol. 15, pp. 2508 - 2514,

Purves TD; Fernyhough P; Tomlinson DR, 2000, 'Activation of mitogen activated protein kinases (MAPKs) in response to cellular stress in adult primary sensory neurones.', EUROPEAN JOURNAL OF NEUROSCIENCE, vol. 12, pp. 302 - 302,

Campbell WE; Gammon DW; Smith P; Abrahams M; Purves TD, 1997, 'Composition and antimalarial activity in vitro of the essential oil of Tetrodenia riparia', Planta Medica, vol. 63, pp. 270 - 272,

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