By Emeritus Professor Rakesh Kumar

Journal articles

Yang M; Kumar RK; Foster P, 2010, 'IFN-gamma and pulmonary macrophages contribute to the mechanisms underlying prolonged airways hyperresponsiveness', Clinical and Experimental Allergy, 40, pp. 163 - 173

Li JJ; Wang W; Baines KJ; Bowden NA; Hansbro PM; Gibson PG; Kumar RK; Foster PS; Yang M, 2010, 'IL-27/IFN- induce MyD88-dependent steroid-resistant airway hyperresponsiveness by inhibiting glucocorticoid signaling in macrophages', Journal of Immunology, 185, pp. 4401 - 4409, http://dx.doi.org/10.4049/jimmunol.1001039

Thorburn AN; O Sullivan BJ; Thomas R; Kumar RK; Foster PS; Gibson PG; Hansbro PM, 2010, 'Pneumococcal conjugate vaccine-induced T regulatory cells suppress the development of allergic airways disease', Thorax, 65, pp. 1053 - 1060

Kumar RK; Hitchins MP; Foster PS, 2009, 'Epigenetic changes in childhood asthma', Disease Models and Mechanisms, 2, pp. 549 - 553

Yang M; Kumar RK; Foster PS, 2009, 'Pathogenesis of Steroid-Resistant Airway Hyperresponsiveness: Interaction between IFN-gamma and TLR4/MyD88 Pathways', Journal of Immunology, 182, pp. 5107 - 5115

Cai Y; Kumar RK; Zhou J; Foster PS; Webb DC, 2009, 'Ym1/2 promotes Th2 cytokine expression and allergic inflammation via inhibition of 12/15-lipoxygenase: Identification of a novel pathway for regulating allergic inflammation', Journal of Immunology, 182, pp. 5393 - 5399

Kumar RK; Herbert C; Foster PS, 2008, 'The "classical" ovalbumin challenge model of asthma in mice', Current Drug Targets, 9, pp. 485 - 494, http://dx.doi.org/10.2174/138945008784533561

Velan GM; Jones PD; McNeil HP; Kumar RK, 2008, 'Integrated online formative assessments in the biomedical sciences for medical students: benefits for learning', BMC Medical Education, 8, pp. 52 - 62, http://dx.doi.org/10.1186/1472-6920-8-52

Ito K; Herbert C; Siegle JS; Vuppusetty C; Hansbro N; Thomas PS; Foster PS; Barnes PJ; Kumar RK, 2008, 'Steroid-Resistant Neutrophilic Inflammation in a Mouse Model of an Acute Exacerbation of Asthma', Am J Respir Cell Mol Biol, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18474669

Herbert C; Hettiaratchi A; Webb DC; Thomas PS; Foster PS; Kumar RK, 2008, 'Suppression of cytokine expression by roflumilast and dexamethasone in a model of chronic asthma', Clin Exp Allergy, 38, pp. 847 - 856, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18307529

Foster PS; Rosenberg H; Asquith K; Kumar RK, 2008, 'Targeting eosinophils in asthma', Current Molecular Medicine, 8, pp. 585 - 590

Vonlaufen A; Xu ZH; Daniel B; Kumar RK; Pirola RC; Wilson JS; Apte MV, 2007, 'Bacterial endotoxin: A trigger factor for alcoholic pancreatitis? Evidence from a novel, physiologically relevant animal model', Gastroenterology, 133, pp. 1293 - 1303, http://dx.doi.org/10.1053/j.gastro.2007.06.062

Siegle JS; Hansbro N; Herbert C; Yang M; Foster PS; Kumar RK, 2006, 'Airway hyperreactivity in exacerbation of chronic asthma is independent of eosinophilic inflammation', Am J Respir Cell Mol Biol, 35, pp. 565 - 570, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16794258

Kumar RK; Freeman B; Velan GM; De Permentier PJ, 2006, 'Integrating histology and histopathology teaching in practical classes using virtual slides', The Anatomical Record Part B, 289B, pp. 128 - 133

Kumar RK; Webb DC; Herbert C; Foster PS, 2006, 'Interferon-gamma as a possible target in chronic asthma', Inflamm Allergy Drug Targets, 5, pp. 253 - 256, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17168796

Shum B; Mackay C; Gorgun C; Frost M; Kumar RK; Hotamisligil G; Rolph MS, 2006, 'The adipocyte fatty acid-binding protein aP2 is required in allergic airway inflammation', Journal of Clinical Investigation, 116, pp. 2183 - 2192

Wei XM; Kim HS; Kumar RK; Heywood GJ; Hunt JE; McNeil HP; Thomas PS, 2005, 'Effects of cigarette smoke on degranulation and NO production by mast cells and epithelial cells', Respiratory Research, 6

Bhindi R; Brieger D; Ishii H; Di Girolamo N; Kumar RK; Khachigian LM; Lowe HC, 2005, 'Fibroblast growth factor 2 and the transcription factor Egr-l localiseto endothelial cell microvascular channels in human coronary artery occlusion', Thrombosis and Haemostasis, 93, pp. 172 - 174

Kumar RK; Hawkins NJ; Harris PJ; Velan GM, 2004, 'Bridging the gap between the scientific and societal aspects of medical education', Journal of the International Association of Medical Science Educators, 14, pp. 15 - 17

Apte MV; Wilson JS; Park S; Phillips PA; Santucci N; Goldstein D; Ramm GA; Buchler M; Friess H; Mccarroll JA; Merrett ND; Pirola RC, 2004, 'Desmoplastic reaction in pancreatic cancer: role of pancreatic stellate cells', Pancreas, 29, pp. 179 - 187

Kumar RK; Herbert C; Webb DC; Li L; Foster PS, 2004, 'Effects of anticytokine therapy in a mouse model of chronic asthma', Am J Respir Crit Care Med, 170, pp. 1043 - 1048, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15306533

Kumar RK; Herbert C; Foster PS, 2004, 'Expression of growth factors by airway epithelial cells in a model of chronic asthma: regulation and relationship to subepithelial fibrosis', Clin Exp Allergy, 34, pp. 567 - 575, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15080809

Mccarroll JA; Phillips PA; Kumar RK; Park S; Pirola RC; Wilson JS; Apte MV, 2004, 'Pancreatic stellate cell migration: role of the phosphatidyl inositol 3-kinase (PI3-kinase) pathway', Biochemical Pharmacology, 67, pp. 1215 - 1225, http://dx.doi.org/10.1016/j.bcp.2003.11.013

Kumar RK; Herbert C; Kasper M, 2004, 'Reversibility of airway inflammation and remodelling following cessation of antigenic challenge in a model of chronic asthma', Clin Exp Allergy, 34, pp. 1796 - 1802, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15544607

Kumar RK; Velan GM; Korell S; Kandara M; Dee FR; Wakefield D, 2004, 'Virtual microscopy for learning and assessment in pathology', Journal of Pathology, 204, pp. 613 - 618

Collins RA; Sly PD; Turner DJ; Herbert C; Kumar RK, 2003, 'Site of inflammation influences site of hyperresponsiveness in experimental asthma', Respiratory Physiology and Neurobiology, 139, pp. 51 - 61, http://dx.doi.org/10.1016/j.resp.2003.09.003

Kumar R; Padha N; Shishodia PK; Mehra RM, 2003, 'Study of dark and photoconductivity of Sb-doped CuInSe 2m thin films', Indian Journal of Pure and Applied Physics, 41, pp. 723 - 726

Ye P; Simonian M; Chapple CC; Gibbins JR; Kumar RK; Hunter N, 2003, 'Differential expression of transforming growth factors-β1, -β2, -β3 and the type I, II, III receptors in the lining epithelia of inflamed gingiva', Pathology, 35, pp. 384 - 392, http://dx.doi.org/10.1080/00313020310001602585

Foster PS; Yang M; Mattes J; Kumar R; Webb D, 2003, 'Interleukin-13 and allergy', Modern Aspects of Immunobiology, 3, pp. 8

Dziegielewski M; Velan GM; Kumar RK, 2003, 'Teaching pathology using 'hotspotted' digital images.', Medical education, 37, pp. 1047 - 1048, http://dx.doi.org/10.1046/j.1365-2923.2003.01646.x

Phillips PA; Wu MJ; Kumar RK; Doherty E; Mccarroll JA; Park S; Pirola RC; Wilson JS; Apte MV, 2003, 'Cell migration: A novel aspect of pancreatic stellate cell biology', Gut, 52, pp. 677 - 682, http://dx.doi.org/10.1136/gut.52.5.677

Foster PS; Webb DC; Yang M; Herbert C; Kumar RK, 2003, 'Dissociation of T helper type 2 cytokine-dependent airway lesions from signal transducer and activator of transcription 6 signalling in experimental chronic asthma', Clin Exp Allergy, 33, pp. 688 - 695

Lan J; Kumar RK; Di Girolamo N; Mccluskey P; Wakefield D, 2003, 'Expression and distribution of matrix metalloproteinases and their inhibitors in the human iris and cilary body', British Journal of Ophthalmology, 87, pp. 208 - 211

Harvey CE; Post JJ; Palladinetti P; Freeman AJ; Ffrench R; Kumar RK; Marinos G; Lloyd AR, 2003, 'Expression of the chemokine IP-10 (CXCL10) by hepatocytes in chronic hepatitis C virus infection correlates with histological severity and lobular inflammation', Journal of Leukocyte Biology, 74, pp. 360 - 369

Kumar RK; Herbert C; Thomas PS; Wollin L; Beume R; Yang M; Webb DC; Foster PS, 2003, 'Inhibition of inflammation and remodeling by roflumilast and dexamethasone in murine chronic asthma', J Pharmacol Exp Ther, 307, pp. 349 - 355, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12954795

Zreiqat H; Kumar RK; Markovic B; Zicat B; Howlett CR, 2003, 'Macrophages at the skeletal tissue-device interface of loosened prosthetic devices express bone-related genes and their products', Journal of Biomedical Materials Research, 65A, pp. 109 - 117

Raftery MJ; Saldanha RG; Geczy C; Kumar RK, 2003, 'Mass spectrometric analysis of electrophoretically separated allergens and proteases in grass pollen diffusates.', Respiratory Research, 4, pp. 10 - 21

Kumar RK, 2002, 'Idiopathic pulmonary fibrosis: An epithelial/fibroblastic cross-talk disorder', Respiratory Research, 3, http://dx.doi.org/10.1186/rr198

Foster PS; Yang M; Herbert C; Kumar RK, 2002, 'CD4(+) T-lymphocytes regulate airway remodeling and hyper-reactivity in a mouse model of chronic asthma', Lab Invest, 82, pp. 455 - 462

Velan GM; Killen MT; Dziegielewski M; Kumar RK, 2002, 'Development and evaluation of a computer-assisted learning module on glomerulonephritis for medical students', Medical Teacher, 24, pp. 412 - 416

Kumar RK; Thomas PS; Seetoo DQ; Herbert C; McKenzie AN; Foster PS; Lloyd AR, 2002, 'Eotaxin expression by epithelial cells and plasma cells in chronic asthma', Lab Invest, 82, pp. 495 - 504, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11950906

Foster PS; Hogan SP; Yang M; Mattes J; Young IR; Matthaei KI; Kumar RK; Mahalingam S; Webb DC, 2002, 'Interleukin-5 and eosinophils as therapeutic targets for asthma', Trends in Molecular Medicine, 8, pp. 162 - 167

Kumar RK; Foster PS, 2002, 'Modeling allergic asthma in mice: pitfalls and opportunities', American Journal of Respiratory Cell and Molecular Biology, 27, pp. 267 - 272

Lee CM; Kumar RK; Lubowski D; Burcher EF, 2002, 'Neuropeptides and nerve growth in inflammatory bowel diseases: a quantitative immunohistochemical study.', Digestive Diseases and Sciences, 47, pp. 495 - 502

Kumar RK; Herbert C; Yang M; Koskinen AM; McKenzie AN; Foster PS, 2002, 'Role of interleukin-13 in eosinophil accumulation and airway remodelling in a mouse model of chronic asthma', Clin Exp Allergy, 32, pp. 1104 - 1111, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12100061

Kumar RK; Foster PS, 2002, 'ST2: marker, activator and regulator of Th2 immunity?', Clinical and Experimental Allergy, 32, pp. 1394 - 1396

Di Girolamo N; Kumar RK; Coroneo MT; Wakefield D, 2002, 'UVB-Mediated Induction of Interleukin-6 and -8 in Pterygia and Cultured Human Pterygium Epithelial Cells', Investigative Ophthalmology and Visual Science, 43, pp. 3430 - 3437

Velan GM; Kumar RK; Dziegielewski M; Wakefield D, 2002, 'Web-based self-assessments in Pathology with Questionmark Perception', Pathology, 34, pp. 282 - 284

Kumar RK; Yang Z; Bilson S; Thliveris S; Cooke BE; Geczy CL, 2001, 'Dimeric S100A8 in human neutrophils is diminished after phagocytosis', Journal of Leukocyte Biology, 70, pp. 59 - 64

Lowe HC; Kumar RK; Chesterman CN; Fahmy R; Khachigian LM, 2001, 'Coronary Stent Thrombosis: Insights from the Porcine Coronary Stent Model', Journal of Thrombosis and Thrombolysis, pp. 937 - 938

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