By Professor Beng Hock Chong

Journal articles

Cai H; Cho EA; Li Y; Sockler J; Parish CR; Chong BH; Edwards J; Dodds TJ; Ferguson PM; Wilmott JS; Scolyer RA; Halliday GM; Khachigian LM, 2018, 'Melanoma protective antitumor immunity activated by catalytic DNA', Oncogene, 37, pp. 5115 - 5126, http://dx.doi.org/10.1038/s41388-018-0306-0

Lee KH; Cavanaugh L; Leung H; Yan F; Ahmadi Z; Chong BH; Passam F, 2018, 'Quantification of NETs-associated markers by flow cytometry and serum assays in patients with thrombosis and sepsis', International Journal of Laboratory Hematology, 40, pp. 392 - 399, http://dx.doi.org/10.1111/ijlh.12800

Sun X; Zhao YN; Qian S; Gao RL; Yin LM; Wang LP; Chong BH; Zhang SZ, 2018, 'Ginseng-Derived Panaxadiol Saponins Promote Hematopoiesis Recovery in Cyclophosphamide-Induced Myelosuppressive Mice: Potential Novel Treatment of Chemotherapy-Induced Cytopenias', Chinese Journal of Integrative Medicine, 24, pp. 200 - 206, http://dx.doi.org/10.1007/s11655-017-2754-8

Perdomo J; Yan F; Leung HHL; Chong BH, 2017, 'Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34⁺ Cells', Journal of Visualized Experiments, http://dx.doi.org/10.3791/56420-v

Perdomo JS; Yan F; Leung HH; Chong BH, 2017, 'Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells', Journal of Visualized Experiments, 2017, http://dx.doi.org/10.3791/56420

Cines DB; Wasser J; Rodeghiero F; Chong BH; Steurer M; Provan D; Lyons R; Garcia-Chavez J; Carpenter N; Wang X; Eisen M, 2017, 'Safety and efficacy of romiplostim in splenectomized and nonsplenectomized patients with primary immune thrombocytopenia', Haematologica, 102, pp. 1342 - 1351, http://dx.doi.org/10.3324/haematol.2016.161968

Yang M; Liang E; Mao L; Li C; Chong BH, 2016, 'Notoginsenoside R1 Has Thrombopoietic Effect in Irradiated Mice', Blood, 128, pp. 4932 - 4932, http://dx.doi.org/10.1182/blood.v128.22.4932.4932

Li Xia Z; Mo Y; Jie Yu Y; Chong BH, 2016, 'PDGFR Inhibitor Imatinib May be a Potent Drug in Treating Essential Thrombocythemia', Blood, 128, pp. 5470 - 5470, http://dx.doi.org/10.1182/blood.v128.22.5470.5470

Yang M; Ye J; Liang E; Li C; Chong BH, 2016, 'The Ex-Vivo Expansion of Megakaryocytic Progenitors from Hematopoietic Stem Cells for Thrombocytopenia in NOD/SCID Mice', Blood, 128, pp. 3746 - 3746, http://dx.doi.org/10.1182/blood.v128.22.3746.3746

Yang M; Liu L; Liang E; Chong BH; Li C, 2016, 'Thrombopoietin Has Neural Protective Effect in a Neonatal Rat Model of Hypoxic-Ischemic Brain Damage', Blood, 128, pp. 5059 - 5059, http://dx.doi.org/10.1182/blood.v128.22.5059.5059

Yang M; Liang E; Mao L; Chong BH; Li C, 2016, 'Thrombospondin-1 Induces Apoptosis in Megakaryocytic Leukemia Via CD36 and Caspase-3 Signaling', Blood, 128, pp. 5209 - 5209, http://dx.doi.org/10.1182/blood.v128.22.5209.5209

Janssens A; Rodeghiero F; Anderson D; Chong BH; Boda Z; Pabinger I; Červinek L; Terrell DR; Wang X; Franklin J, 2016, 'Changes in bone marrow morphology in adults receiving romiplostim for the treatment of thrombocytopenia associated with primary immune thrombocytopenia', Annals of Hematology, 95, pp. 1077 - 1087, http://dx.doi.org/10.1007/s00277-016-2682-2

Zheng SS; Chong JJH; Chong BH, 2016, 'Pharmacodynamics, pharmacokinetics and clinical efficacy of apixaban in the treatment of thrombosis', Expert Opinion on Drug Metabolism and Toxicology, 12, pp. 575 - 580, http://dx.doi.org/10.1517/17425255.2016.1164692

Wei A; Shen B; Williams LA; Bhargav D; Yan F; Chong BH; Diwan AD, 2016, 'Expression and functional roles of estrogen receptor GPR30 in human intervertebral disc', Journal of Steroid Biochemistry and Molecular Biology, 158, pp. 46 - 55, http://dx.doi.org/10.1016/j.jsbmb.2016.01.012

Yang M; Liang EY; Zhou LX; Chong BH; Li C, 2015, 'Lung Damage and Thrombocytopenia', Blood, 126, pp. 4638 - 4638, http://dx.doi.org/10.1182/blood.v126.23.4638.4638

Zhou LX; Ye J; Liang EY; Li C; Chong BH; Yang M, 2015, 'PDGF/PDGFR May be Involved in the Physiopathologic Mechanism of Essential Thrombocythemia', Blood, 126, pp. 5208 - 5208, http://dx.doi.org/10.1182/blood.v126.23.5208.5208

Liang EY; Ye JY; Zhou LX; Li C; Chong BH; Yang M, 2015, 'Platelet-Derived Serotonin Stimulates TPO Production from Bone Marrow Mesenchymal Stromal Cells but Not Hepatocytes', Blood, 126, pp. 4773 - 4773, http://dx.doi.org/10.1182/blood.v126.23.4773.4773

Choi PY; Roncolato F; Badoux X; Ramanathan S; Ho SJ; Chong BH, 2015, 'A novel triple therapy for ITP using high-dose dexamethasone, low-dose rituximab, and cyclosporine (TT4)', Blood, 126, pp. 500 - 503, http://dx.doi.org/10.1182/blood-2015-03-631937

Pang JH; Coupland LA; Freeman C; Chong BH; Parish CR, 2015, 'Activation of tumour cell ECM degradation by thrombin-activated platelet membranes: potentially a P-selectin and GPIIb/IIIa-dependent process', Clinical and Experimental Metastasis, 32, pp. 495 - 505, http://dx.doi.org/10.1007/s10585-015-9722-5

Bakchoul T; Fuhrmann J; Chong BH; Bougie D; Aster R, 2015, 'Recommendations for the use of the non-obese diabetic/severe combined immunodeficiency mouse model in autoimmune and drug-induced thrombocytopenia: Communication from the SSC of the ISTH', Journal of Thrombosis and Haemostasis, 13, pp. 872 - 875, http://dx.doi.org/10.1111/jth.12879

Lin X; Yin L; Gao R; Liu Q; Xu W; Jiang X; Chong BH, 2015, 'The effects of panaxadiol saponins on megakaryocytic maturation and immune function in a mouse model of immune thrombocytopenia', Experimental Hematology, 43, pp. 364 - 373, http://dx.doi.org/10.1016/j.exphem.2014.12.008

Fraser ST; Midwinter RG; Coupland LA; Kong S; Berger BS; Yeo JH; Andrade OC; Cromer D; Suarna C; Lam M; Maghzal GJ; Chong BH; Parish CR; Stocker R, 2015, 'Heme oxygenase-1 deficiency alters erythroblastic Island formation, steady-state erythropoiesis and red blood cell lifespan in mice', Haematologica, 100, pp. 601 - 610, http://dx.doi.org/10.3324/haematol.2014.116368

Iraqi M; Perdomo J; Yan F; Choi PYI; Chong BH, 2015, 'Immune thrombocytopenia: Antiplatelet autoantibodies inhibit proplatelet formation by megakaryocytes and impair platelet production in vitro', Haematologica, 100, pp. 623 - 632, http://dx.doi.org/10.3324/haematol.2014.115634

Janssens A; Rodeghiero F; Anderson D; Chong B; Boda Z; Pabinger I; Cervinek L; Wang X; Lopez A, 2014, 'Final Results from a Phase 4 Open-Label 3-Year Study Evaluating Changes in Bone Marrow (Bm) Morphology in Adult Immune Thrombocytopenia (ITP) Patients (Pts) Receiving the Thrombopoietin Mimetic Romiplostim', BLOOD, 124, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000349233806210&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Boonyawat K; Angchaisuksiri P; Aryurachai K; Chaiyaroj S; Ahmadi Z; Chong BHO, 2014, 'Low prevalence of heparin-induced thrombocytopenia after cardiac surgery in Thai patients', Thrombosis research, 134, pp. 957 - 962, http://dx.doi.org/10.1016/j.thromres.2014.08.020

Ye JY; Liang EY; Cheng YS; Chan GCF; Ding Y; Meng F; Ng MHL; Chong BH; Lian Q; Yang M, 2014, 'Serotonin enhances megakaryopoiesis and proplatelet formation via p-Erk1/2 and F-actin reorganization', Stem Cells, 32, pp. 2973 - 2982, http://dx.doi.org/10.1002/stem.1777

Maghzal GJ; Winter S; Wurzer B; Chong BH; Holmdahl R; Stocker R, 2014, 'Tryptophan catabolism is unaffected in chronic granulomatous disease', Nature, 514, pp. E16 - E17, http://dx.doi.org/10.1038/nature13844

Carter DR; Buckle AD; Tanaka K; Perdomo J; Chong BH, 2014, 'Art27 interacts with GATA4, FOG2 and NKX2.5 and is a novel co-repressor of cardiac genes', PLoS ONE, 9, http://dx.doi.org/10.1371/journal.pone.0095253

Nandurkar H; Chong B; Salem H; Gallus A; Ferro V; Mckinnon R, 2014, 'Low-molecular-weight heparin biosimilars: Potential implications for clinical practice', Internal Medicine Journal, 44, pp. 497 - 500, http://dx.doi.org/10.1111/imj.12417

Braidy N; Gai W-P; Xu YH; Sachdev P; Guillemin GJ; Jiang X-M; Ballard JWO; Horan MP; Fang ZM; Chong BH; Chan DKY, 2014, 'Alpha-Synuclein Transmission and Mitochondrial Toxicity in Primary Human Foetal Enteric Neurons In Vitro', Neurotoxicity Research, 25, pp. 170 - 182, http://dx.doi.org/10.1007/s12640-013-9420-5

Sanchez-Guerrero E; Chen E; Kockx M; An S-W; Chong BH; Khachigian LM, 2013, 'Correction: IL-1beta Signals through the EGF Receptor and Activates Egr-1 through MMP-ADAM', PLoS ONE, 8, http://dx.doi.org/10.1371/annotation/a0bc2cbb-0390-4476-833d-30ce4f829794

Lee LH; Caguioa P; Chin NS; Chiou TJ; Lee JW; Miyakawa Y; Tambunan KL; Chong BH, 2013, 'Erratum to: Chronic adult primary immune thrombocytopenia (ITP) in the Asia-pacific region (International Journal of Hematology (2011) 94 (142-149) DOI 10.1007/s12185-011-0894-8)', International Journal of Hematology, 98, pp. 729, http://dx.doi.org/10.1007/s12185-013-1457-y

Yang M; Chen JL; Ye JY; Li SY; Liang EY; Chong B, 2013, 'Angelica Polysaccharide and TPO Have a Protective Effect On Hcmv-Induced Apoptosis In Megakaryocytes', Blood, 122, pp. 3553 - 3553, http://dx.doi.org/10.1182/blood.v122.21.3553.3553

Yang M; Jiang Q; Xiao B; Liu C; Li SY; Huang LF; Chong B; Meng FY, 2013, 'Astragalus Polysaccharide has hematopoietic and thrombopoietic activities in an irradiation mouse model', Blood, 122, pp. 4216 - 4216, http://dx.doi.org/10.1182/blood.v122.21.4216.4216

Yang M; Zhou M; Li SY; Chong B; Li XJ, 2013, 'IL-1β Plays An Important Role On Thrombocytosis In An Immune Vasculitis Model Via Promoting Megakaryopoiesis', Blood, 122, pp. 2325 - 2325, http://dx.doi.org/10.1182/blood.v122.21.2325.2325

Ye JY; Li SY; Liang EY; Meng FY; Chong B; Yang M, 2013, 'Imatinib mesylate has an inhibitory effect on hematopoiesis in a mice model', Blood, 122, pp. 5568 - 5568, http://dx.doi.org/10.1182/blood.v122.21.5568.5568

Janssens A; Rodeghiero F; Anderson D; Chong B; Boda Z; Pabinger I; Cervinek L; Wang X; Lopez A, 2013, 'Results From a Phase IV Open-Label Study Evaluating Changes In Bone Marrow Morphology In Adult Immune Thrombocytopenia (ITP) Patients Receiving Romiplostim: Analysis Of The 1- and 2-Year Romiplostim Cohorts', Blood, 122, pp. 2312 - 2312, http://dx.doi.org/10.1182/blood.v122.21.2312.2312

Ye JY; Meng FY; Jiang Q; Li SY; Liang EY; Chong B; Yang M, 2013, 'Serotonin and Its Metabolism Enhances Megakaryopoiesis and Proplatelet Formation', Blood, 122, pp. 4753 - 4753, http://dx.doi.org/10.1182/blood.v122.21.4753.4753

Yang M; Wu FQ; Zhou M; Ye JY; Li XJ; Chong B; Liu C, 2013, 'Tanshinone IIA has anti-platelet effect and induces apoptosis in megakaryocytes via TNFR and Caspases', Blood, 122, pp. 3635 - 3635, http://dx.doi.org/10.1182/blood.v122.21.3635.3635

Young-Ill Choi P; Ng S-C; Lee C; Roncolato F; Badoux X; Hugman AJ; Ramanathan S; Ho S-J; Lee S-H; Chong B, 2013, 'Triple Therapy For Immune Thrombocytopenia: A Novel Combination Of Conventional Strategies To Safely Sustain Platelet Counts In ITP', Blood, 122, pp. 1084 - 1084, http://dx.doi.org/10.1182/blood.v122.21.1084.1084

Braidy N; Gai WP; Xu YH; Sachdev P; Guillemin GJ; Jiang XM; Ballard JWO; Horan MP; Fang ZM; Chong BH; Chan DKY, 2013, 'Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblasts', Translational Neurodegeneration, 2, pp. 20, http://dx.doi.org/10.1186/2047-9158-2-20

Coupland LA; Chong BH; Parish CR, 2013, 'Beware of NK cells in pre-clinical metastasis models', Clinical and Experimental Metastasis, 30, pp. 945 - 947, http://dx.doi.org/10.1007/s10585-013-9582-9

Greinacher A; Warkentin TE; Chong BH, 2013, 'Heparin-Induced Thrombocytopenia', , pp. 851 - 882, http://dx.doi.org/10.1016/B978-0-12-387837-3.00042-0

Chong BH; Chong JJH, 2013, 'HIT: Nucleic acid masquerading as heparin', Blood, 122, pp. 156 - 158, http://dx.doi.org/10.1182/blood-2013-05-504126

Choi PY; Chong BH, 2013, 'Successfully sparing splenectomy in immune thrombocytopenia purpura (ITP)', JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 11, pp. 301 - 301, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000331833602009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Perdomo J; Jiang XM; Carter DR; Khachigian LM; Chong BH, 2013, 'Correction: SUMOylation regulates the transcriptional repression activity of FOG-2 and its association with GATA-4 (PLoS ONE)', PLoS ONE, 8, http://dx.doi.org/10.1371/annotation/3d7a31cd-09e7-47d1-af57-c58c7082058d

Sanchez-Guerrero E; Jo SR; Chong BH; Khachigian LM, 2013, 'EGFR and the complexity of receptor crosstalk in the cardiovascular system', Current Molecular Medicine, 13, pp. 3 - 12, http://dx.doi.org/10.2174/156652413804486313

Perdomo JS; Yan F; Chong BH, 2013, 'A megakaryocyte with no platelets: Anti-platelet antibodies, apoptosis, and platelet production.', Platelets, 24, pp. 98 - 106, http://dx.doi.org/10.3109/09537104.2012.669508

Chong BH; Choi PY; Khachigian LM; Perdomo JS, 2013, 'Drug-induced immune thrombocytopenia', Hematology - Oncology Clinics of North America, 27, pp. 521 - 540, http://dx.doi.org/10.1016/j.hoc.2013.02.003

Lee LH; Caguioa P; Chin NS; Chiou T-J; Lee JW; Miyakawa Y; Tambunan KL; Chong BH, 2013, 'Erratum to: Chronic adult primary immune thrombocytopenia (ITP) in the Asia-Pacific region', International Journal of Hematology, pp. 1 - 1, http://dx.doi.org/10.1007/s12185-013-1457-y

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