Select Publications
Book Chapters
2018, 'Considerations for optimal use of postmortem human brains for molecular psychiatry: lessons from schizophrenia', in Handbook of Clinical Neurology, pp. 221 - 235, http://dx.doi.org/10.1016/B978-0-444-63639-3.00016-5
,2017, 'Schizophrenia and related psychotic disorders', in Bloch S; Green SA; Janca A; Mitchell PB; Robertson M (ed.), Foundations of Clinical Psychiatry Fourth Edition, Melbourne University Press, Calrton, Victoria, pp. 316 - 341
,Journal articles
2025, 'Divergent changes in complement pathway gene expression in schizophrenia and bipolar disorder: Links to inflammation and neurogenesis in the subependymal zone', Schizophrenia Research, 275, pp. 25 - 34, http://dx.doi.org/10.1016/j.schres.2024.11.005
,2024, 'Antipsychotic-induced prolactin elevation in premenopausal women with schizophrenia: associations with estrogen, disease severity and cognition', Archives of Women's Mental Health, 27, pp. 931 - 941, http://dx.doi.org/10.1007/s00737-024-01491-9
,2024, 'RNA-sequencing suggests extracellular matrix and vasculature dysregulation could impair neurogenesis in schizophrenia cases with elevated inflammation', Schizophrenia, 10, http://dx.doi.org/10.1038/s41537-024-00466-0
,2024, 'Molecular Evidence for Altered Angiogenesis in Neuroinflammation-Associated Schizophrenia and Bipolar Disorder Implicate an Abnormal Midbrain Blood-Brain Barrier.', Schizophr Bull, http://dx.doi.org/10.1093/schbul/sbae184
,2024, 'Schizophrenia-associated changes in neuronal subpopulations in the human midbrain.', Brain, http://dx.doi.org/10.1093/brain/awae321
,2024, 'Increased Parenchymal Macrophages are associated with decreased Tyrosine Hydroxylase mRNA levels in the Substantia Nigra of people with Schizophrenia and Bipolar Disorder', Psychiatry Research, 340, http://dx.doi.org/10.1016/j.psychres.2024.116141
,2024, 'Molecular evidence of altered stress responsivity related to neuroinflammation in the schizophrenia midbrain', Journal of Psychiatric Research, 177, pp. 118 - 128, http://dx.doi.org/10.1016/j.jpsychires.2024.07.004
,2024, 'The association of prolactin and gonadal hormones with cognition and symptoms in men with schizophrenia spectrum disorder: Divergent effects of testosterone and estrogen', Schizophrenia Research, 270, pp. 273 - 280, http://dx.doi.org/10.1016/j.schres.2024.06.022
,2024, 'Maternal immune activation and estrogen receptor modulation induce sex-specific dopamine-related behavioural and molecular alterations in adult rat offspring', Brain, Behavior, and Immunity, 118, pp. 236 - 251, http://dx.doi.org/10.1016/j.bbi.2024.02.034
,2024, 'Single-Nucleus RNA-Seq Characterizes the Cell Types Along the Neuronal Lineage in the Adult Human Subependymal Zone and Reveals Reduced Oligodendrocyte Progenitor Abundance with Age', eNeuro, 11, pp. 1 - 19, http://dx.doi.org/10.1523/ENEURO.0246-23.2024
,2024, 'Toll-Like Receptor mRNA Levels in Schizophrenia: Association With Complement Factors and Cingulate Gyrus Cortical Thinning', Schizophrenia Bulletin, 50, pp. 403 - 417, http://dx.doi.org/10.1093/schbul/sbad171
,2024, 'Sex- and suicide-specific alterations in the kynurenine pathway in the anterior cingulate cortex in major depression', Neuropsychopharmacology, 49, pp. 584 - 592, http://dx.doi.org/10.1038/s41386-023-01736-8
,2024, 'A path to novel, effective treatments for schizophrenia', Neuropsychopharmacology, 49, pp. 321 - 322, http://dx.doi.org/10.1038/s41386-023-01705-1
,2024, 'Adjunctive canakinumab reduces peripheral inflammation markers and improves positive symptoms in people with schizophrenia and inflammation: A randomized control trial', Brain, Behavior, and Immunity, 115, pp. 191 - 200, http://dx.doi.org/10.1016/j.bbi.2023.10.012
,2024, 'Correction to: Obesity and brain structure in schizophrenia – ENIGMA study in 3021 individuals (Molecular Psychiatry, (2022), 27, 9, (3731-3737), 10.1038/s41380-022-01616-5)', Molecular Psychiatry, 29, pp. 56, http://dx.doi.org/10.1038/s41380-023-02055-6
,2024, 'Peripheral inflammatory markers in melancholic versus non-melancholic depression', Psychoneuroendocrinology, 159, http://dx.doi.org/10.1016/j.psyneuen.2023.106418
,2023, 'Cytomegalovirus antibodies are associated with mood disorders, suicide, markers of neuroinflammation, and microglia activation in postmortem brain samples', Molecular Psychiatry, 28, pp. 5282 - 5292, http://dx.doi.org/10.1038/s41380-023-02162-4
,2023, 'Genetic variation in glutamatergic genes moderates the effects of childhood adversity on brain volume and IQ in treatment-resistant schizophrenia', Schizophrenia, 9, http://dx.doi.org/10.1038/s41537-023-00381-w
,2023, 'Dopaminergic signalling and behavioural alterations by Comt–Dtnbp1 genetic interaction and their clinical relevance', British Journal of Pharmacology, 180, pp. 2514 - 2531, http://dx.doi.org/10.1111/bph.16147
,2023, 'Inflammatory subgroups of schizophrenia and their association with brain structure: A semi-supervised machine learning examination of heterogeneity', Brain, Behavior, and Immunity, 113, pp. 166 - 175, http://dx.doi.org/10.1016/j.bbi.2023.06.023
,2023, 'Changes in cytokine and cytokine receptor levels during postnatal development of the human dorsolateral prefrontal cortex', Brain, Behavior, and Immunity, 111, pp. 186 - 201, http://dx.doi.org/10.1016/j.bbi.2023.03.015
,2023, 'Increased prefrontal cortical cells positive for macrophage/microglial marker CD163 along blood vessels characterizes a neuropathology of neuroinflammatory schizophrenia', Brain, Behavior, and Immunity, 111, pp. 46 - 60, http://dx.doi.org/10.1016/j.bbi.2023.03.018
,2023, 'Interaction between Peripheral and Central immune markers in Clinical High Risk for Psychosis', Brain, Behavior, and Immunity - Health, 30, http://dx.doi.org/10.1016/j.bbih.2023.100636
,2023, 'Perturbed iron biology in the prefrontal cortex of people with schizophrenia', Molecular Psychiatry, 28, pp. 2058 - 2070, http://dx.doi.org/10.1038/s41380-023-01979-3
,2023, 'Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium', Proceedings of the National Academy of Sciences of the United States of America, 120, pp. 1 - 12, http://dx.doi.org/10.1073/pnas.2213880120
,2023, 'GRIN2B gene expression is increased in the anterior cingulate cortex in major depression', Journal of Psychiatric Research, 160, pp. 204 - 209, http://dx.doi.org/10.1016/j.jpsychires.2023.02.017
,2023, 'Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations', Nature Genetics, 55, pp. 369 - 376, http://dx.doi.org/10.1038/s41588-023-01305-1
,2023, 'Neuroimmune transcriptome changes in patient brains of psychiatric and neurological disorders', Molecular Psychiatry, 28, pp. 710 - 721, http://dx.doi.org/10.1038/s41380-022-01854-7
,2023, 'GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors', American Journal of Psychiatry, 180, pp. 723 - 738, http://dx.doi.org/10.1176/appi.ajp.21121266
,2022, 'Cancer activates microglia to the same extent as chronic stress throughout stress neurocircuitry in a mouse model of breast cancer', Psychoneuroendocrinology, 146, http://dx.doi.org/10.1016/j.psyneuen.2022.105938
,2022, 'Identifying gene expression profiles associated with neurogenesis and inflammation in the human subependymal zone from development through aging', Scientific Reports, 12, http://dx.doi.org/10.1038/s41598-021-03976-4
,2022, 'Increased levels of a pro-inflammatory IgG receptor in the midbrain of people with schizophrenia', Journal of Neuroinflammation, 19, http://dx.doi.org/10.1186/s12974-022-02541-8
,2022, 'Peripheral NF-κB dysregulation in people with schizophrenia drives inflammation: putative anti-inflammatory functions of NF-κB kinases', Translational Psychiatry, 12, pp. 21, http://dx.doi.org/10.1038/s41398-021-01764-2
,2022, 'The effects of preventative cannabidiol in a male neuregulin 1 mouse model of schizophrenia', Frontiers in Cellular Neuroscience, 16, http://dx.doi.org/10.3389/fncel.2022.1010478
,2022, 'Single-nucleus RNA sequencing of midbrain blood-brain barrier cells in schizophrenia reveals subtle transcriptional changes with overall preservation of cellular proportions and phenotypes', Molecular Psychiatry, 27, pp. 4731 - 4740, http://dx.doi.org/10.1038/s41380-022-01796-0
,2022, 'The role of the microbiome in the metabolic health of people with schizophrenia and related psychoses: cross-sectional and pre-post lifestyle intervention analyses', Pathogens, 11, pp. 1279, http://dx.doi.org/10.3390/pathogens11111279
,2022, 'The impact of smoking status on cognition and brain morphology in schizophrenia spectrum disorders', Psychological Medicine, 52, pp. 3097 - 3115, http://dx.doi.org/10.1017/S0033291720005152
,2022, 'Dysbindin-1A modulation of astrocytic dopamine and basal ganglia dependent behaviors relevant to schizophrenia', Molecular Psychiatry, 27, pp. 4201 - 4217, http://dx.doi.org/10.1038/s41380-022-01683-8
,2022, 'Increased immune cell and altered microglia and neurogenesis transcripts in an Australian schizophrenia subgroup with elevated inflammation', Schizophrenia Research, 248, pp. 208 - 218, http://dx.doi.org/10.1016/j.schres.2022.08.025
,2022, 'Inflammation-related transcripts define “high” and “low” subgroups of individuals with schizophrenia and bipolar disorder in the midbrain', Brain, Behavior, and Immunity, 105, pp. 149 - 159, http://dx.doi.org/10.1016/j.bbi.2022.06.012
,2022, 'Obesity and brain structure in schizophrenia – ENIGMA study in 3021 individuals', Molecular Psychiatry, 27, pp. 3731 - 3737, http://dx.doi.org/10.1038/s41380-022-01616-5
,2022, 'Virtual Ontogeny of Cortical Growth Preceding Mental Illness', Biological Psychiatry, 92, pp. 299 - 313, http://dx.doi.org/10.1016/j.biopsych.2022.02.959
,2022, 'Distinct Phenotypes of Inflammation Associated Macrophages and Microglia in the Prefrontal Cortex Schizophrenia Compared to Controls', Frontiers in Neuroscience, 16, http://dx.doi.org/10.3389/fnins.2022.858989
,2022, 'Early Life Stress Alters Expression of Glucocorticoid Stress Response Genes and Trophic Factor Transcripts in the Rodent Basal Ganglia', International Journal of Molecular Sciences, 23, http://dx.doi.org/10.3390/ijms23105333
,2022, 'Maternal immune activation with high molecular weight poly(I:C) in Wistar rats leads to elevated immune cell chemoattractants', Journal of Neuroimmunology, 364, http://dx.doi.org/10.1016/j.jneuroim.2022.577813
,2022, 'Alterations in the kynurenine pathway and excitatory amino acid transporter-2 in depression with and without psychosis: Evidence of a potential astrocyte pathology', Journal of Psychiatric Research, 147, pp. 203 - 211, http://dx.doi.org/10.1016/j.jpsychires.2021.12.039
,2022, 'Peripheral complement is increased in schizophrenia and inversely related to cortical thickness', Brain, Behavior, and Immunity, 101, pp. 423 - 434, http://dx.doi.org/10.1016/j.bbi.2021.11.014
,2022, 'Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors', Biological Psychiatry, 91, pp. 313 - 327, http://dx.doi.org/10.1016/j.biopsych.2021.05.029
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