By Professor Cynthia Shannon Weickert

Journal articles

Duncan CE; Schofield PR; Weickert CS, 2009, 'Kv channel interacting protein 3 expression and regulation by haloperidol in midbrain dopaminergic neurons', Brain Research, 1304, pp. 1 - 13, http://dx.doi.org/10.1016/j.brainres.2009.09.045

Wong J; Shannon-Weickert C, 2009, 'Transcriptional interaction of an estrogen receptor slice variant and ErbB4 suggests convergence in gene susceptibility pathways in schizophrenia', The Journal of Biological Chemistry, 284, pp. 18824 - 18832

Somel M; Franz H; Yan Z; Lorenc A; Guo S; Giger T; Kelso J; Nickel B; Dannemann M; Bahn S; Webster MJ; Weickert CS; Lachmann M; Paabo S; Khaitovich P, 2009, 'Transcriptional neoteny in the human brain', Proceedings of the National Academy of Sciences of the United States of America, 106, pp. 5743 - 5748

Chong VZ; Thompson M; Beltaifa S; Webster MJ; Law AJ; Weickert CS, 2008, 'Elevated neuregulin-1 and ErbB4 protein in the prefrontal cortex of schizophrenic patients', Schizophrenia Research, 100, pp. 270 - 280, http://dx.doi.org/10.1016/j.schres.2007.12.474

Duncan C; Sivagnanasundaram S; Webster M; Elashoff M; Bahn S; Shannon Weickert C, 2008, 'DEVELOPMENTAL REGULATION OF GABAA RECEPTOR a-SUBUNITS IN THE HUMAN BRAIN', Schizophrenia Research, 102, pp. 220 - 220, http://dx.doi.org/10.1016/s0920-9964(08)70665-0

Sivagnanasundaram S; Bahn S; Elashoff M; Webster M; Weickert C, 2008, 'EXPRESSION OF DOUBLECORTIN DURING HUMAN CORTICAL DEVELOPMENT', Schizophrenia Research, 102, pp. 222 - 223, http://dx.doi.org/10.1016/s0920-9964(08)70672-8

Montague D; Shannon-Weickert C; Tomaskovic-Crook E; Rothmond D; Kleinman JE; Rubinow DR, 2008, 'Oestrogen receptor alpha localisation in the prefrontal cortex of three mammalian species', Journal of Neuroendocrinology, 20, pp. 893 - 903

Shannon-Weickert C; Rothmond D; Hyde T; Kleinman JE; Straub R, 2008, 'Reduced DTNBP1 (dysbindin-1) mRNA in the hippocampal formation of schizophrenia patients', Schizophrenia Research, 98, pp. 105 - 110, http://dx.doi.org/10.1016/j.schres.2007.05.041

Kim WS; Weickert CS; Garner B, 2008, 'Role of ATP‐binding cassette transporters in brain lipid transport and neurological disease', Journal of Neurochemistry, 104, pp. 1145 - 1166, http://dx.doi.org/10.1111/j.1471-4159.2007.05099.x

Weickert T; Carr VJ; Weickert CS, 2008, 'Second generation antipsychotics reduce treatment discontinuation rates compared with haloperidol', Evidence-Based Mental Health, 11, pp. 115 - 115

Chong VZ; Webster MA; Rothmond D; Shannon-Weickert C, 2008, 'Specific developmental reductions in subveentricular zone ErbB1 and ErbB4 mRNA in the human brain', International Journal of Developmental Neuroscience, 26, pp. 791 - 803

Shannon-Weickert C; Miranda-Angulo A; Wong J; Perlman WR; Ward SE; Radhakrishna V; Straub R; Weinberger DR; Kleinman JE, 2008, 'Variants in the estrogen receptor alpha gene and its mRNA contribute to risk for schizophrenia', Human Molecular Genetics, 17, pp. 2293 - 2309, http://dx.doi.org/10.1093/hmg/ddn130

Perlman WR; Webster MA; Herman M; Kleinman JE; Shannon-Weickert C, 2007, 'Age-related differences in glucocorticoid receptor mRNA levels in the human brain', Neurobiology of Aging, 28, pp. 447 - 458

tunbridge EM; Shannon-Weickert C; Kleinman JE; Herman M; Chen J; Kolachana BS; Harrison PJ; Weinberger DR, 2007, 'Catechol-o-Methyltransferase Enzyme Activity and Protein Expression in Human Prefrontal Cortex across the Postnatal Lifespan', Cerebral cortex, 17, pp. 1206 - 1212

Law A; Kleinman JE; Weinberger DR; Shannon-Weickert C, 2007, 'Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia', Human Molecular Genetics, 16, pp. 129 - 141

Shannon-Weickert C; Webster MA; Gondipalli P; Rothmond D; Fatula RJ; Herman M; Kleinman JE; Akil M, 2007, 'Postnatal alterations in dopaminergic markers in the human prefrontal cortex', Neuroscience, 144, pp. 1109 - 1119

Thompson M; Lauderdale S; Webster MA; Chong VZ; McClintock B; Saunders R; Shannon-Weickert C, 2007, 'Widespread expression of ErbB2, ErbB3 and ErbB4 in non-human primate brain', Brain Research, 1139, pp. 95 - 109

Eastwood SL; Weickert CS; Webster MJ; Herman MM; Kleinman JE; Harrison PJ, 2006, 'Synaptophysin protein and mRNA expression in the human hippocampal formation from birth to old age', Hippocampus, 16, pp. 645 - 654, http://dx.doi.org/10.1002/hipo.20194

Webster MJ; Herman MM; Kleinman JE; Shannon Weickert C, 2006, 'BDNF and trkB mRNA expression in the hippocampus and temporal cortex during the human lifespan', Gene Expression Patterns, 6, pp. 941 - 951, http://dx.doi.org/10.1016/j.modgep.2006.03.009

Lipska BK; Deep-Soboslay A; Weickert CS; Hyde TM; Martin CE; Herman MM; Kleinman JE, 2006, 'Critical Factors in Gene Expression in Postmortem Human Brain: Focus on Studies in Schizophrenia', Biological Psychiatry, 60, pp. 650 - 658, http://dx.doi.org/10.1016/j.biopsych.2006.06.019

Law AJ; Lipska BK; Weickert CS; Hyde TM; Straub RE; Hashimoto R; Harrison PJ; Kleinman JE; Weinberger DR, 2006, 'Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5′ SNPs associated with the disease', Proceedings of the National Academy of Sciences, 103, pp. 6747 - 6752, http://dx.doi.org/10.1073/pnas.0602002103

Lipska BK; Peters T; Hyde TM; Halim N; Horowitz C; Mitkus S; Weickert CS; Matsumoto M; Sawa A; Straub RE; Vakkalanka R; Herman MM; Weinberger DR; Kleinman JE, 2006, 'Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs', Human Molecular Genetics, 15, pp. 1245 - 1258, http://dx.doi.org/10.1093/hmg/ddl040

Law AJ; Lipska BK; Weickert CS; Hyde TM; Straub RE; Hashimoto R; Harrison PJ; Kleinman JE; Weinberger DR, 2006, 'Neuregulin 1 Transcripts Are Differentially Expressed in Schizophrenia and Regulated by 5′ SNPs Associated With the Disease', Focus, 4, pp. 350 - 359, http://dx.doi.org/10.1176/foc.4.3.350

Perlman WR; Tomaskovic-Crook E; Montague DM; Webster MJ; Rubinow DR; Kleinman JE; Weickert CS, 2005, 'Alteration in estrogen receptor α mRNA levels in frontal cortex and hippocampus of patients with major mental illness', Biological Psychiatry, 58, pp. 812 - 824, http://dx.doi.org/10.1016/j.biopsych.2005.04.047

Matsumoto M; Beltaifa S; Weickert CS; Herman MM; Hyde TM; Saunders RC; Lipska BK; Weinberger DR; Kleinman JE, 2005, 'A conserved mRNA expression profile of SREB2 (GPR85) in adult human, monkey, and rat forebrain', Molecular Brain Research, 138, pp. 58 - 69, http://dx.doi.org/10.1016/j.molbrainres.2005.04.002

Weickert CS; Ligons DL; Romanczyk T; Ungaro G; Hyde TM; Herman MM; Weinberger DR; Kleinman JE, 2005, 'Reductions in neurotrophin receptor mRNAs in the prefrontal cortex of patients with schizophrenia', Molecular Psychiatry, 10, pp. 637 - 650, http://dx.doi.org/10.1038/sj.mp.4001678

Webster MJ; O'Grady J; Kleinman JE; Weickert CS, 2005, 'Glial fibrillary acidic protein mRNA levels in the cingulate cortex of individuals with depression, bipolar disorder and schizophrenia', Neuroscience, 133, pp. 453 - 461, http://dx.doi.org/10.1016/j.neuroscience.2005.02.037

Beltaifa S; Webster MJ; Ligons DL; Fatula RJ; Herman MM; Kleinman JE; Weickert CS, 2005, 'Discordant changes in cortical TrkC mRNA and protein during the human lifespan', European Journal of Neuroscience, 21, pp. 2433 - 2444, http://dx.doi.org/10.1111/j.1460-9568.2005.04074.x

Weickert CS; Kittell DA; Saunders RC; Herman MM; Horlick RA; Kleinman JE; Hyde TM, 2005, 'Basic fibroblast growth factor and fibroblast growth factor receptor-1 in the human hippocampal formation', Neuroscience, 131, pp. 219 - 233, http://dx.doi.org/10.1016/j.neuroscience.2004.09.070

Perlman WR; Matsumoto M; Beltaifa S; Hyde TM; Saunders RC; Webster MJ; Rubinow DR; Kleinman JE; Weickert CS, 2005, 'Expression of estrogen receptor alpha exon-deleted mRNA variants in the human and non-human primate frontal cortex', Neuroscience, 134, pp. 81 - 95, http://dx.doi.org/10.1016/j.neuroscience.2005.03.055

Perlman WR; Webster MJ; Kleinman JE; Weickert CS, 2004, 'Reduced glucocorticoid and estrogen receptor alpha messenger ribonucleic acid levels in the amygdala of patients with major mental illness', Biological Psychiatry, 56, pp. 844 - 852, http://dx.doi.org/10.1016/j.biopsych.2004.09.006

Egan MF; Straub RE; Goldberg TE; Yakub I; Callicott JH; Hariri AR; Mattay VS; Bertolino A; Hyde TM; Shannon-Weickert C; Akil M; Crook J; Vakkalanka RK; Balkissoon R; Gibbs RA; Kleinman JE; Weinberger DR, 2004, 'Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia', Proceedings of the National Academy of Sciences, 101, pp. 12604 - 12609, http://dx.doi.org/10.1073/pnas.0405077101

Law AJ; Shannon Weickert C; Hyde TM; Kleinman JE; Harrison PJ, 2004, 'Neuregulin-1 (NRG-1) mRNA and protein in the adult human brain', Neuroscience, 127, pp. 125 - 136, http://dx.doi.org/10.1016/j.neuroscience.2004.04.026

Perlman WR; Weickert CS; Akil M; Kleinman JE, 2004, 'Postmortem investigations of the pathophysiology of schizophrenia: The role of susceptibility genes', Journal of Psychiatry and Neuroscience, 29, pp. 287 - 293

Halim ND; Weickert CS; McClintock BW; Weinberger DR; Lipska BK, 2004, 'Effects of chronic haloperidol and clozapine treatment on neurogenesis in the adult rat hippocampus', Neuropsychopharmacology, 29, pp. 1063 - 1069, http://dx.doi.org/10.1038/sj.npp.1300422

Vawter MP; Weickert CS; Ferran E; Matsumoto M; Overman K; Hyde TM; Weinberger DR; Bunney WE; Kleinman JE, 2004, 'Gene expression of metabolic enzymes and a protease inhibitor in the prefrontal cortex are decreased in schizophrenia', Neurochemical Research, 29, pp. 1245 - 1255, http://dx.doi.org/10.1023/B:NERE.0000023611.99452.47

Weickert CS; Straub RE; McClintock BW; Matsumoto M; Hashimoto R; Hyde TM; Herman MM; Weinberger DR; Kleinman JE, 2004, 'Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain', Archives of General Psychiatry, 61, pp. 544 - 555, http://dx.doi.org/10.1001/archpsyc.61.6.544

Wang J; Cheng CM; Zhou J; Smith A; Weickert CS; Perlman WR; Becker KG; Powell D; Bondy CA, 2004, 'Estradiol Alters Transcription Factor Gene Expression in Primate Prefrontal Cortex', Journal of Neuroscience Research, 76, pp. 306 - 314, http://dx.doi.org/10.1002/jnr.20076

Hashimoto R; Straub RE; Weickert CS; Hyde TM; Kleinman JE; Weinberger DR, 2004, 'Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia', Molecular Psychiatry, 9, pp. 299 - 307, http://dx.doi.org/10.1038/sj.mp.4001434

Smith A; Wang J; Cheng CM; Zhou J; Weickert CS; Bondy CA, 2004, 'High-Level Expression of Dok-1 in Neurons of the Primate Prefrontal Cortex and Hippocampus', Journal of Neuroscience Research, 75, pp. 218 - 224, http://dx.doi.org/10.1002/jnr.10842

Ghose S; Weickert CS; Colvin SM; Coyle JT; Herman MM; Hyde TM; Kleinman JE, 2004, 'Glutamate Carboxypeptidase II Gene Expression in the Human Frontal and Temporal Lobe in Schizophrenia', Neuropsychopharmacology, 29, pp. 117 - 125, http://dx.doi.org/10.1038/sj.npp.1300304

Law AJ; Weickert CS; Hyde TM; Kleinman JE; Harrison PJ, 2004, 'Reduced spinophilin but not microtubule-associated protein 2 expression in the hippocampal formation in schizophrenia and mood disorders: Molecular evidence for a pathology of dendritic spines', American Journal of Psychiatry, 161, pp. 1848 - 1855, http://dx.doi.org/10.1176/ajp.161.10.1848

Perlman WR; Weickert CS; Akil M; Kleinman JE, 2004, 'Postmortem investigations of the pathophysiology of schizophrenia: the role of susceptibility genes', Journal of Psychiatry and Neuroscience, 29, pp. 287 - 293, http://dx.doi.org/10.1139/jpn.0430

Shanon-Weickert C; Kozlovsky N; Tomaskovic-Crook E; Kleinman JE; Belmaker RH; Agam G; Shannon Weickert C, 2004, 'Reduced GSK-alpha mRNA levels in postmortem dorsolateral prefrontal cortex of schizophrenic patients.', Journal of Neural Transmission, 111, pp. 1583 - 1592, http://dx.doi.org/10.1007/s00702-004-0166-3

Halim ND; Weickert CS; McClintock BW; Hyde TM; Weinberger DR; Kleinman JE; Lipska BK, 2003, 'Presynaptic proteins in the prefrontal cortex of patients with schizophrenia and rats with abnormal prefrontal development', Molecular Psychiatry, 8, pp. 797 - 810, http://dx.doi.org/10.1038/sj.mp.4001319

Law AJ; Weickert CS; Webster MJ; Herman MM; Kleinman JE; Harrison PJ, 2003, 'Expression of NMDA receptor NR1, NR2A and NR2B subunit mRNAs during development of the human hippocampal formation', European Journal of Neuroscience, 18, pp. 1197 - 1205, http://dx.doi.org/10.1046/j.1460-9568.2003.02850.x

Weickert CS; Hyde TM; Lipska BK; Herman MM; Weinberger DR; Kleinman JE, 2003, 'Reduced brain-derived neurotrophic factor in prefrontal cortex of patients with schizophrenia', Molecular Psychiatry, 8, pp. 592 - 610, http://dx.doi.org/10.1038/sj.mp.4001308

Matsumoto M; Weickert CS; Beltaifa S; Kolachana B; Chen J; Hyde TM; Herman MM; Weinberger DR; Kleinman JE, 2003, 'Catechol O-methyltransferase (COMT) mRNA expression in the dorsolateral prefrontal cortex of patients with schizophrenia', Neuropsychopharmacology, 28, pp. 1521 - 1530, http://dx.doi.org/10.1038/sj.npp.1300218

Matsumoto M; Weickert CS; Akil M; Lipska BK; Hyde TM; Herman MM; Kleinman JE; Weinberger DR, 2003, 'Catechol O-methyltransferase mRNA expression in human and rat brain: Evidence for a role in cortical neuronal function', Neuroscience, 116, pp. 127 - 137, http://dx.doi.org/10.1016/S0306-4522(02)00556-0

Carrasco E; Blum M; Weickert CS; Casper D, 2003, 'Epidermal growth factor receptor expression is related to post-mitotic events in cerebellar development: Regulation by thyroid hormone', Developmental Brain Research, 140, pp. 1 - 13, http://dx.doi.org/10.1016/S0165-3806(02)00539-4

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