By Professor Georgina Hold

Journal articles

Gemmell MR; Jayawardana T; Koentgen S; Brooks E; Kennedy N; Berry S; Lees C; Hold GL, 2024, 'Optimised human stool sample collection for multi-omic microbiota analysis', Scientific Reports, 14, http://dx.doi.org/10.1038/s41598-024-67499-4

Noble A; Adams A; Nowak J; Cheng G; Nayak K; Quinn A; Kristiansen M; Kalla R; Ventham NT; Giachero F; Jayamanne C; Hansen R; Hold GL; El-Omar E; Croft NM; Wilson D; Beattie RM; Ashton JJ; Zilbauer M; Ennis S; Uhlig HH; Satsangi J, 2024, 'The circulating methylome in childhood-onset inflammatory bowel disease.', J Crohns Colitis, http://dx.doi.org/10.1093/ecco-jcc/jjae157

Katsoudas N; Tavakoli P; Wu N; Shapiro A; Leach ST; Williams AJ; Paramsothy R; Ghaly S; Connor SJ; Samocha-Bonet D; Lambert K; Hold GL, 2024, 'Dietary Emulsifier Exposure in People with Inflammatory Bowel Disease Compared with Healthy Controls: Is There a Cause for Concern?', Inflammatory Bowel Diseases, 30, pp. 1241 - 1250, http://dx.doi.org/10.1093/ibd/izad318

Little RD; McKenzie J; Srinivasan A; Hilley P; Gilmore RB; Chee D; Sandhu M; Saitta D; Chow E; Thin L; Walker GJ; Moore GT; Lynch K; Andrews J; An YK; Bryant RV; Connor SJ; Garg M; Wright EK; Hold G; Segal JP; Boussioutas A; De Cruz P; Ward MG; Sparrow MP, 2024, 'Switching from Dose-Intensified intravenous to SubCutaneoUS infliximab in Inflammatory Bowel Disease (DISCUS-IBD): protocol for a multicentre randomised controlled trial', BMJ Open, 14, http://dx.doi.org/10.1136/bmjopen-2023-081787

Ariaee A; Koentgen S; Wardill HR; Hold GL; Prestidge CA; Armstrong HK; Joyce P, 2024, 'Prebiotic selection influencing inflammatory bowel disease treatment outcomes: A review of the preclinical and clinical evidence', eGastroenterology, 2, http://dx.doi.org/10.1136/egastro-2023-100055

Little RD; Jayawardana T; Koentgen S; Zhang F; Connor SJ; Boussioutas A; Ward MG; Gibson PR; Sparrow MP; Hold GL, 2024, 'Pathogenesis and precision medicine for predicting response in inflammatory bowel disease: Advances and future directions', eGastroenterology, 2, http://dx.doi.org/10.1136/egastro-2023-100006

Cosier D; Lambert K; Batterham M; Charlton K; Hold G, 2024, 'Positive relationship between plant diversity dietary patterns and disease activity in Australian adults with Inflammatory Bowel Disease', Proceedings of the Nutrition Society, 83, http://dx.doi.org/10.1017/s0029665124000867

Rimmer P; Scott G; Quraishi MN; Hazel K; Cooney R; Zhang F; Hold GL; Gordon M; Iqbal T; Hansen R, 2024, 'Sa1887 IS DIVERSITY IMPORTANT IN THE GUT MICROBIOME AT IBD ONSET? A SYSTEMATIC REVIEW OF THE LITERATURE AND META-ANALYSIS OF ALPHA-DIVERSITY DATA', Gastroenterology, 166, http://dx.doi.org/10.1016/s0016-5085(24)01772-4

Oosterlinck B; Ceuleers H; Arras W; De Man JG; Geboes K; De Schepper H; Peeters M; Lebeer S; Skieceviciene J; Hold GL; Kupcinskas J; Link A; De Winter BY; Smet A, 2023, 'Mucin-microbiome signatures shape the tumor microenvironment in gastric cancer', Microbiome, 11, http://dx.doi.org/10.1186/s40168-023-01534-w

Baumdick ME; Niehrs A; Degenhardt F; Schwerk M; Hinrichs O; Jordan-Paiz A; Padoan B; Wegner LHM; Schloer S; Zecher BF; Malsy J; Joshi VR; Illig C; Schröder-Schwarz J; Möller KJ; Akar A; Flemming C; Felix ; Flomm ; Flosbach M; Jäger J; Jeromin N; Jung J; Ohms M; Reinshagen K; Rische J; Sagebiel A; Sandfort D; Steinert F; Tomuschat C; Wesche J; Martin MP; Yuki Y; Ozawa M; Sauter J; Schmidt AH; Perez D; Giannou AD; Carrington M; Davis RS; Schumacher U; Sauter G; Huber S; Puelles VG; Melling N; Franke A; Shifteh Abedian ; Abraham C; Achkar JP; Ahmad T; Alberts R; Alizadeh B; Amininejad L; Ananthakrishnan AN; Andersen V; Anderson CA; Andrews JM; Annese V; Aumais G; Baidoo L; Baldassano RN; Bampton PA; Barclay M; Barrett JC; Bethge J; Bewshea C; Bis JC; Bitton A; BK T; Boucher G; Brain O; Brand S; Brant SR; Cheon JH; Chew A; Cho JH; Cleynen I; Cohain A; Cooney R; Croft A; Daly MJ; D'Amato M; Danese S; Daryani NE; Datta LW; Denapiene G; Denson LA; Devaney KL; Dewit O; D'Inca R; Drummond HE; Dubinsky M; Duerr RH; Edwards C; Ellinghaus D; Ellul P; Esaki M; Essers J; Ferguson LR; Festen EA, 2023, 'HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44⁺ Natural Killer Cells in Ulcerative Colitis', Gastroenterology, 165, pp. 946 - 962.e13, http://dx.doi.org/10.1053/j.gastro.2023.06.034

Rokkas T; Hold GL, 2023, 'A systematic review, pairwise meta-analysis and network meta-analysis of randomized controlled trials exploring the role of fecal microbiota transplantation in irritable bowel syndrome', European Journal of Gastroenterology and Hepatology, 35, pp. 471 - 479, http://dx.doi.org/10.1097/MEG.0000000000002519

Mah C; Jayawardana T; Leong G; Koentgen S; Lemberg D; Connor SJ; Rokkas T; Grimm MC; Leach ST; Hold GL, 2023, 'Assessing the Relationship between the Gut Microbiota and Inflammatory Bowel Disease Therapeutics: A Systematic Review', Pathogens, 12, http://dx.doi.org/10.3390/pathogens12020262

Zhang F; Gia A; Chen G; Gong L; Behary J; Hold GL; Zekry A; Tang X; Sun Y; El-Omar E; Jiang XT, 2023, 'Critical Assessment of Whole Genome and Viral Enrichment Shotgun Metagenome on the Characterization of Stool Total Virome in Hepatocellular Carcinoma Patients', Viruses, 15, pp. 53, http://dx.doi.org/10.3390/v15010053

Oosterlinck B; Arras W; De Man J; Geboes K; De Schepper HU; Peeters M; Lebeer S; Skieceviciene J; Hold GL; Kupcinskas J; Link A; De Winter BY; Smet A, 2023, 'Sa1865 MUCIN-MICROBIOME SIGNATURES SHAPE THE TUMOUR MICROENVIRONMENT IN GASTRIC CANCER', Gastroenterology, 164, pp. S - 468, http://dx.doi.org/10.1016/s0016-5085(23)02079-6

O'Donnell M; Teasdale S; Chua X-Y; Hardman J; Wu N; Curtis J; Samaras K; Bolton P; Morris M; Shannon-Weickert C; Purves-Tyson T; El-Assaad F; Jiang X; Hold G; El-Omar E; Wu N, 2022, 'The role of the microbiome in the metabolic health of people with schizophrenia and related psychoses: cross-sectional and pre-post lifestyle intervention analyses', Pathogens, 11, pp. 1279, http://dx.doi.org/10.3390/pathogens11111279

Little RD; Ward MG; Wright E; Jois AJ; Boussioutas A; Hold GL; Gibson PR; Sparrow MP, 2022, 'Therapeutic Drug Monitoring of Subcutaneous Infliximab in Inflammatory Bowel Disease—Understanding Pharmacokinetics and Exposure Response Relationships in a New Era of Subcutaneous Biologics', Journal of Clinical Medicine, 11, http://dx.doi.org/10.3390/jcm11206173

Carserides C; Smith K; Zinicola M; Kumar A; Swedrowska M; Scala C; Cameron G; Riches Z; Iannelli F; Pozzi G; Hold GL; Forbes B; Kelly C; Hijazi K, 2022, 'Comprehensive Study of Antiretroviral Drug Permeability at the Cervicovaginal Mucosa via an In Vitro Model', Pharmaceutics, 14, http://dx.doi.org/10.3390/pharmaceutics14091938

Gulliver EL; Young RB; Chonwerawong M; D'Adamo GL; Thomason T; Widdop JT; Rutten EL; Rossetto Marcelino V; Bryant RV; Costello SP; O'Brien CL; Hold GL; Giles EM; Forster SC, 2022, 'Review article: the future of microbiome-based therapeutics', Alimentary Pharmacology and Therapeutics, 56, pp. 192 - 208, http://dx.doi.org/10.1111/apt.17049

Breugelmans T; Oosterlinck B; Arras W; Ceuleers H; De Man J; Hold GL; De Winter BY; Smet A, 2022, 'The role of mucins in gastrointestinal barrier function during health and disease', The Lancet Gastroenterology and Hepatology, 7, pp. 455 - 471, http://dx.doi.org/10.1016/S2468-1253(21)00431-3

James KR; Elmentaite R; Teichmann SA; Hold GL, 2022, 'Redefining intestinal immunity with single-cell transcriptomics', Mucosal Immunology, 15, pp. 531 - 541, http://dx.doi.org/10.1038/s41385-021-00470-y

James KR; Elmentaite R; Teichmann SA; Hold GL, 2022, 'Correction to: Redefining intestinal immunity with single-cell transcriptomics (Mucosal Immunology, (2021), 10.1038/s41385-021-00470-y)', Mucosal Immunology, 15, pp. 526 - 526, http://dx.doi.org/10.1038/s41385-022-00483-1

Amorim N; McGovern E; Raposo A; Khatiwada S; Shen S; Koentgen S; Hold G; Behary J; El-Omar E; Zekry A, 2022, 'Refining a Protocol for Faecal Microbiota Engraftment in Animal Models After Successful Antibiotic-Induced Gut Decontamination', Frontiers in Medicine, 9, http://dx.doi.org/10.3389/fmed.2022.770017

Shaw S; Berry S; Thomson J; Murray GI; El-Omar E; Hold GL, 2022, 'Gut Mucosal Microbiome Signatures of Colorectal Cancer Differ According to BMI Status', Frontiers in Medicine, 8, http://dx.doi.org/10.3389/fmed.2021.800566

Smet A; Kupcinskas J; Link A; Hold GL; Bornschein J, 2022, 'The Role of Microbiota in Gastrointestinal Cancer and Cancer Treatment: Chance or Curse?', Cellular and Molecular Gastroenterology and Hepatology, 13, pp. 857 - 874, http://dx.doi.org/10.1016/j.jcmgh.2021.08.013

Wu N; Mah C; Koentgen S; Zhang L; Grimm MC; El-Omar E; Hold GL, 2021, 'Inflammatory bowel disease and the gut microbiota', Proceedings of the Nutrition Society, 80, pp. 424 - 434, http://dx.doi.org/10.1017/S002966512100197X

Hansen R; Bajaj-Elliott M; Hold GL; Gerasimidis K; Iqbal TH; Amos G; Thomas LV; Marchesi JR, 2021, 'Next-generation sequencing as a clinical laboratory tool for describing different microbiotas: An urgent need for future paediatric practice', Archives of Disease in Childhood, 106, pp. 1035, http://dx.doi.org/10.1136/archdischild-2021-321683

Lambert K; Pappas D; Miglioretto C; Javadpour A; Reveley H; Frank L; Grimm MC; Samocha-Bonet D; Hold GL, 2021, 'Systematic review with meta-analysis: dietary intake in adults with inflammatory bowel disease', Alimentary Pharmacology and Therapeutics, 54, pp. 742 - 754, http://dx.doi.org/10.1111/apt.16549

Nelson A; Stewart CJ; Kennedy NA; Lodge JK; Tremelling M; Probert CS; Parkes M; Mansfield JC; Smith DL; Hold GL; Lees CW; Bridge SH; Lamb CA, 2021, 'The Impact of NOD2 Genetic Variants on the Gut Mycobiota in Crohn's Disease Patients in Remission and in Individuals without Gastrointestinal Inflammation', Journal of Crohn's and Colitis, 15, pp. 800 - 812, http://dx.doi.org/10.1093/ecco-jcc/jjaa220

Bornschein J; Tran-Nguyen T; Fernandez-Esparrach G; Ash S; Balaguer F; Bird-Lieberman EL; Córdova H; Dzerve Z; Fassan M; Leja M; Lyutakov I; Middelburg T; Moreira L; Nakov R; Nieuwenburg SAV; O'Connor A; Realdon S; De Schepper H; Smet A; Spaander MCW; Tolmanis I; Urbonas T; Weigt J; Hold GL; Link A; Kupcinskas J, 2021, 'Biopsy Sampling in Upper Gastrointestinal Endoscopy: A Survey from 10 Tertiary Referral Centres across Europe', Digestive Diseases, 39, pp. 179 - 189, http://dx.doi.org/10.1159/000511867

Mahalhal A; Burkitt MD; Duckworth CA; Hold GL; Campbell BJ; Pritchard DM; Probert CS, 2021, 'Long‐term iron deficiency and dietary iron excess exacerbate acute dextran sodium sulphate‐induced colitis and are associated with significant dysbiosis', International Journal of Molecular Sciences, 22, http://dx.doi.org/10.3390/ijms22073646

Keller JJ; Ooijevaar RE; Hvas CL; Terveer EM; Lieberknecht SC; Högenauer C; Arkkila P; Sokol H; Gridnyev O; Mégraud F; Kump PK; Nakov R; Goldenberg SD; Satokari R; Tkatch S; Sanguinetti M; Cammarota G; Dorofeev A; Gubska O; Ianiro G; Mattila E; Arasaradnam RP; Sarin SK; Sood A; Putignani L; Alric L; Baunwall SMD; Kupcinskas J; Link A; Goorhuis AG; Verspaget HW; Ponsioen C; Hold GL; Tilg H; Kassam Z; Kuijper EJ; Gasbarrini A; Mulder CJJ; Williams HRT; Vehreschild MJGT, 2021, 'A standardised model for stool banking for faecal microbiota transplantation: a consensus report from a multidisciplinary UEG working group', United European Gastroenterology Journal, 9, pp. 229 - 247, http://dx.doi.org/10.1177/2050640620967898

Williams AJ; Paramsothy R; Wu N; Ghaly S; Leach S; Paramsothy S; Corte C; O'Brien C; Burke C; Wark G; Samocha-Bonet D; Lambert K; Ahlenstiel G; Wasinger V; Dutt S; Pavli P; Grimm M; Lemberg D; Connor S; Leong R; Hold G, 2021, 'Australia IBD Microbiome (AIM) Study: Protocol for a multicentre longitudinal prospective cohort study', BMJ Open, 11, http://dx.doi.org/10.1136/bmjopen-2020-042493

Susic D; Davis G; O' Sullivan AJ; McGovern E; Harris K; Roberts LM; Craig ME; Mangos G; Hold GL; El-Omar EM; Henry A; O'Sullivan A, 2020, 'Microbiome Understanding in Maternity Study (MUMS), an Australian prospective longitudinal cohort study of maternal and infant microbiota: study protocol', BMJ open, 10, pp. e040189, http://dx.doi.org/10.1136/bmjopen-2020-040189

Link A; Hold G, 2020, 'First Case of Covid-19 in the United States', The New England journal of medicine, 382, pp. e53, http://dx.doi.org/10.1056/NEJMc2004794

Bezawada N; Phang TH; Hold GL; Hansen R, 2020, 'Autism Spectrum Disorder and the Gut Microbiota in Children: A Systematic Review', Annals of Nutrition and Metabolism, 76, pp. 16 - 29, http://dx.doi.org/10.1159/000505363

Rajilic-Stojanovic M; Figueiredo C; Smet A; Hansen R; Kupcinskas J; Rokkas T; Andersen L; Machado JC; Ianiro G; Gasbarrini A; Leja M; Gisbert JP; Hold GL, 2020, 'Systematic review: gastric microbiota in health and disease', Alimentary Pharmacology and Therapeutics, 51, pp. 582 - 602, http://dx.doi.org/10.1111/apt.15650

Ormsby MJ; Johnson SA; Carpena N; Meikle LM; Goldstone RJ; McIntosh A; Wessel HM; Hulme HE; McConnachie CC; Connolly JPR; Roe AJ; Hasson C; Boyd J; Fitzgerald E; Gerasimidis K; Morrison D; Hold GL; Hansen R; Walker D; Smith DGE; Wall DM, 2020, 'Propionic Acid Promotes the Virulent Phenotype of Crohn's Disease-Associated Adherent-Invasive Escherichia coli', Cell Reports, 30, pp. 2297 - 2305.e5, http://dx.doi.org/10.1016/j.celrep.2020.01.078

Keller JJ; Vehreschild MJGT; Hvas CL; Jorgensen SMD; Kupciskas J; Link A; Mulder CJJ; Goldenberg SD; Arasaradnam R; Sokol H; Gasbarrini A; Hoegenauer C; Terveer EM; Kuijper EJ; Arkkila P; Gasbarrini A; Gridnyev O; Megraud F; Kump PK; Nakov R; Goldenberg SD; Satokari R; Tkatch S; Sanguinetti M; Sokol H; Cammarota G; Dorofeev A; Keller JJ; Hoegenauer C; Gubska O; Ianiro G; Mattila E; Ooijevaar RE; Arasaradnam R; Sarin SK; Sood A; Putignani L; Alric L; Arkkila P; Hvas CL; Jorgensen SMD; Kuijper EJ; Kupciskas J; Link A; Mulder CJJ; Williams HRT; Goorhuis A; Verspaget HW; Terveer EM; Hold GL; Tilg H; Ponsioen CY, 2019, 'Stool for fecal microbiota transplantation should be classified as a transplant product and not as a drug', UNITED EUROPEAN GASTROENTEROLOGY JOURNAL, 7, pp. 1408 - 1410, http://dx.doi.org/10.1177/2050640619887579

Gemmell M; Berry S; Mukhopadhya I; Gong L; Hansen R; Hold G, 2019, 'Draft genome sequences of a Campylobacter curvus and three Campylobacter ureolyticus strains isolated from human colonic mucosal tissue', Microbiota in Health and Disease, 1, pp. e148 - e148, http://dx.doi.org/10.26355/mhd_201911_148

Rokkas T; Gisbert JP; Gasbarrini A; Hold GL; Tilg H; Malfertheiner P; Megraud F; O'Morain C, 2019, 'A network meta-analysis of randomized controlled trials exploring the role of fecal microbiota transplantation in recurrent Clostridium difficile infection', United European Gastroenterology Journal, 7, pp. 1051 - 1063, http://dx.doi.org/10.1177/2050640619854587

Hold GL; Allen-Vercoe E, 2019, 'Gut microbial biofilm composition and organisation holds the key to CRC', Nature Reviews Gastroenterology and Hepatology, 16, pp. 329 - 330, http://dx.doi.org/10.1038/s41575-019-0148-4

Ormsby MJ; Logan M; Johnson SA; McIntosh A; Fallata G; Papadopoulou R; Papachristou E; Hold GL; Hansen R; Ijaz UZ; Russell RK; Gerasimidis K; Wall DM, 2019, 'Inflammation associated ethanolamine facilitates infection by Crohn's disease-linked adherent-invasive Escherichia coli', EBioMedicine, 43, pp. 325 - 332, http://dx.doi.org/10.1016/j.ebiom.2019.03.071

Mukhopadhya I; Segal JP; Carding SR; Hart AL; Hold GL, 2019, 'The gut virome: the ‘missing link’ between gut bacteria and host immunity?', Therapeutic Advances in Gastroenterology, 12, http://dx.doi.org/10.1177/1756284819836620

Hsu T; Gemmell MR; Franzosa EA; Berry S; Mukhopadhya I; Hansen R; Michaud M; Nielsen H; Miller WG; Nielsen H; Bajaj-Elliott M; Huttenhower C; Garrett WS; Hold GL, 2019, 'Comparative genomics and genome biology of Campylobacter showae', Emerging Microbes and Infections, 8, pp. 827 - 840, http://dx.doi.org/10.1080/22221751.2019.1622455

Hold GL; Hansen R, 2019, 'Impact of the gastrointestinal microbiome in health and disease: Co-evolution with the host immune system', , 421, pp. 303 - 318, http://dx.doi.org/10.1007/978-3-030-15138-6_12

Bond A; Greenwood R; Lewis S; Corfe B; Sarkar S; O’Toole P; Rooney P; Burkitt M; Hold G; Probert C, 2019, 'Volatile organic compounds emitted from faeces as a biomarker for colorectal cancer', Alimentary Pharmacology and Therapeutics, 49, pp. 1005 - 1012, http://dx.doi.org/10.1111/apt.15140

Mahalhal A; Burkitt M; Duckworth C; Hold G; Campbell B; Pritchard M; Probert C, 2019, 'Long-term iron deficiency and iron supplementation exacerbate acute DSS-induced colitis and are associated with significant dysbiosis', , http://dx.doi.org/10.1101/585174

Hansen R; Gibson S; De Paiva Alves E; Goddard M; MacLaren A; Karcher AM; Berry S; Collie-Duguid ESR; El-Omar E; Munro M; Hold GL, 2018, 'Adaptive response of neonatal sepsis-derived Group B Streptococcus to bilirubin', Scientific Reports, 8, pp. 6470, http://dx.doi.org/10.1038/s41598-018-24811-3

Gemmell MR; Berry S; Mukhopadhya I; Hansen R; Nielsen HL; Bajaj-Elliott M; Nielsen H; Hold GL, 2018, 'Comparative genomics of Campylobacter concisus: Analysis of clinical strains reveals genome diversity and pathogenic potential', Emerging Microbes and Infections, 7, http://dx.doi.org/10.1038/s41426-018-0118-x

Ianiro G; Maida M; Burisch J; Simonelli C; Hold G; Ventimiglia M; Gasbarrini A; Cammarota G, 2018, 'Efficacy of different faecal microbiota transplantation protocols for Clostridium difficile infection: A systematic review and meta-analysis', United European Gastroenterology Journal, 6, pp. 1232 - 1244, http://dx.doi.org/10.1177/2050640618780762

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