By Professor John Myburgh

Journal articles

B V; S F; J C; D R; Y A; R B; L B; M C; P G; M H; C J; Q L; C M; A P; A R; K T; S W; J M, 2018, 'Adjunctive Glucocorticoid Therapy in Patients with Septic Shock', Yearbook of Paediatric Endocrinology, http://dx.doi.org/10.1530/ey.15.8.12

Finfer S; Myburgh J; Bellomo R, 2018, 'Intravenous fluid therapy in critically ill adults', Nature Reviews Nephrology, 14, pp. 541 - 557, http://dx.doi.org/10.1038/s41581-018-0044-0

Reddi B; Finnis M; Udy AA; Maiden M; Delaney A; Bellomo R; Peake S, 2018, 'The relationship between the change in central venous pressure and intravenous fluid volume in patients presenting to the emergency department with septic shock', Intensive Care Medicine, 44, pp. 1591 - 1592, http://dx.doi.org/10.1007/s00134-018-5314-6

Venkatesh B; Finfer S; Myburgh J, 2018, 'Glucocorticoids with or without Fludrocortisone in Septic Shock Reply', NEW ENGLAND JOURNAL OF MEDICINE, 379, pp. 895 - 895, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000443047800023&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Thompson K; Taylor C; Jan S; Li Q; Hammond N; Myburgh J; Saxena M; Venkatesh B; Finfer S, 2018, 'Health-related outcomes of critically ill patients with and without sepsis', Intensive Care Medicine, 44, pp. 1249 - 1257, http://dx.doi.org/10.1007/s00134-018-5274-x

Myburgh JA, 2018, 'Intracranial pressure thresholds in severe traumatic brain injury: Pro', Intensive Care Medicine, 44, pp. 1315 - 1317, http://dx.doi.org/10.1007/s00134-018-5264-z

Roberts I; Shakur H; Bellomo R; Bion J; Finfer S; Hunt B; Myburgh J; Perner A; Reinhart K, 2018, 'Should hydroxyethyl starch be banned? – Authors' reply', The Lancet, 392, pp. 119, http://dx.doi.org/10.1016/S0140-6736(18)31179-6

Rygård SL; Butler E; Granholm A; Møller MH; Cohen J; Finfer S; Perner A; Myburgh J; Venkatesh B; Delaney A, 2018, 'Low-dose corticosteroids for adult patients with septic shock: a systematic review with meta-analysis and trial sequential analysis', Intensive Care Medicine, 44, pp. 1003 - 1016, http://dx.doi.org/10.1007/s00134-018-5197-6

Wang Y; Gallagher M; Li Q; Lo S; Cass A; Finfer S; Myburgh J; Bouman C; Faulhaber-Walter R; Kellum JA; Palevsky PM; Ronco C; Saudan P; Tolwani A; Bellomo R, 2018, 'Renal replacement therapy intensity for acute kidney injury and recovery to dialysis independence: A systematic review and individual patient data meta-analysis', Nephrology Dialysis Transplantation, 33, pp. 1017 - 1024, http://dx.doi.org/10.1093/ndt/gfx308

Maiden MJ; Finnis ME; Peake S; McRae S; Delaney A; Bailey M; Bellomo R, 2018, 'Haemoglobin concentration and volume of intravenous fluids in septic shock in the ARISE trial', Critical Care, 22, http://dx.doi.org/10.1186/s13054-018-2029-6

Venkatesh B; Finfer S; Myburgh J; Cohen J; Billot L, 2018, 'Long-Term outcomes of the ADRENAL trial', New England Journal of Medicine, 378, pp. 1744 - 1745, http://dx.doi.org/10.1056/NEJMc1803563

Presneill J; Gantner D; Nichol A; McArthur C; Forbes A; Kasza J; Trapani T; Murray L; Bernard S; Cameron P; Capellier G; Huet O; Newby L; Rashford S; Rosenfeld JV; Smith T; Stephenson M; Varma D; Vallance S; Walker T; Webb S; Cooper DJ, 2018, 'Statistical analysis plan for the POLAR-RCT: The Prophylactic hypOthermia trial to Lessen trAumatic bRain injury-Randomised Controlled Trial', TRIALS, 19, http://dx.doi.org/10.1186/s13063-018-2610-y

Aubron C; Kandane-Rathnayake RK; Andrianopoulos N; Westbrook A; Engelbrecht S; Ozolins I; Bailey M; Murray L; Cooper DJ; Wood EM; McQuilten ZK; Pettilä V; Nichol A; Phillips LE; Street A; French C; Orford N; Santamaria J; Bellomo R; Vallance S; McArthur C; McGuiness S; Newby L; Simmonds C; Parke R; Buhr H; Goldsmith D; O'Sullivan K; Mercer I; Gazzard R; Tauschke C; Hill D; Fletcher J; Boschert C; Koch G; Ernest D; Eliott S; Howe B; Hawker F; Ellem K; Duff K; Henderson S; Mehrtens J; Milliss D; O'Bree B; Shepherd K; Ihle B; Ho S; Graan M; Bernsten A; Ryan E; Botha J; Vuat J; Kinmonth A; Fraser M; Richards B; Tallott M; Whitbread R; Freebairn R; Thomas L; Parr M; Micallef S; Deshpande K; Wood J; Williams T; Tai J; Boase A; Galt P; King B; Price R; Tomlinson J; Cole L; Seppelt I; Weisbrodt L; Gresham R; Nikas M; Laing J; Bell J; McHugh G; Hancock D; Kirkham S; Shehabi Y; Campbell M; Stockdale V; Peake S; Williams P; Sharley P; O'Connor S; Stephens D; Thomas J; Sistla R; McAllister R; Marsden K; MacIsaac C; Barge D; Caf T; Finfer S; Tan L; Bird S; Webb S, 2018, 'Day or overnight transfusion in critically ill patients: does it matter?', Vox Sanguinis, 113, pp. 275 - 282, http://dx.doi.org/10.1111/vox.12635

O'Brien Z; Cass A; Cole L; Finfer S; Gallagher M; McArthur C; McGuiness S; Myburgh J; Bellomo R; Mårtensson J, 2018, 'Higher versus Lower Continuous Renal Replacement Therapy Intensity in Critically ill Patients with Liver Dysfunction', Blood Purification, 45, pp. 36 - 43, http://dx.doi.org/10.1159/000480224

Venkatesh B; Finfer S; Cohen J; Rajbhandari D; Arabi Y; Bellomo R; Billot L; Correa M; Glass P; Harward M; Joyce C; Li Q; McArthur C; Perner A; Rhodes A; Thompson K; Webb S; Myburgh J; Saxena M, 2018, 'Adjunctive glucocorticoid therapy in patients with septic shock', New England Journal of Medicine, 378, pp. 797 - 808, http://dx.doi.org/10.1056/NEJMoa1705835

Myburgh J, 2018, 'Patient-centered outcomes and resuscitation fluids', New England Journal of Medicine, 378, pp. 862 - 863, http://dx.doi.org/10.1056/NEJMe1800449

Roberts I; Shakur H; Bellomo R; Bion J; Finfer S; Hunt B; Myburgh J; Perner A; Reinhart K, 2018, 'Hydroxyethyl starch solutions and patient harm', The Lancet, 391, pp. 736, http://dx.doi.org/10.1016/S0140-6736(18)30255-1

Shehabi Y; Bellomo R; Kadiman S; Ti LK; Howe B; Reade MC; Khoo TM; Alias A; Wong YL; Mukhopadhyay A; McArthur C; Seppelt I; Webb SA; Green M; Bailey MJ; Ibrom E; Maher C; Mashonganyika C; McKee H; Bennett V; Cooper DJ; Vallance S; Eastwood G; Peck L; Young H; Eliott S; Mercer I; Sidhu J; Whitfield A; Ding G; Hatfield P; Smith K; Coles T; Dennett J; Summers T; Ruther A; Anderson R; Jones E; Milliss D; Wong H; Botha J; Allsop S; Kanhere M; Wood J; Hogan C; Tai J; Williams T; Buckley A; Garrett P; McDonald S; Cuzner C; Weisbrodt L; Bass F; Edhouse P; Sana M; Chamberlain J; Bicknell A; Roberts B; Casey E; Cheng A; Inskip D; Myburgh J; Holmes J; Santamaria J; Smith R; Nair P; Reynolds C; Johnson B; Sterba M; Wong KK; Venugopal S; Rai V; Shahnaz M; Ramoo V; Jose S; Ozturk O; Ramlee SNZ; Foon BS; Amran R; Narula RKA; Md Ramly ES; Hapiz KA; I-Liang L; Morad MHC; Ali MN; Raihan HN; Azizum SI; Suzana Y; Haryati H; Zawati SS; Ismeev JN; Zulkarnain MA; Omar M; Omar SA; Ismail SR; Hassan N; Zakaria Z; Mohtar S; Ahmad M, 2018, 'Sedation intensity in the first 48 hours of mechanical ventilation and 180-day mortality: A multinational prospective longitudinal cohort study', Critical Care Medicine, 46, pp. 850 - 859, http://dx.doi.org/10.1097/CCM.0000000000003071

Myburgh J, 2017, 'The evolution of intensive care medicine: a personal journey', Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 19, pp. 287 - 289

Peake SL; Delaney A; Bailey M; Bellomo R; Bennett V; Board J; McCracken P; McGloughlin S; Nanjayya V; Teo A; Hill E; Jones P; O'Brien E; Sawtell F; Schimanski K; Wilson D; Bolch S; Eastwood G; Kerr F; Peak L; Young H; Edington J; Fletcher J; Smith J; Ghelani D; Nand K; Sara T; Cross A; Flemming D; Grummisch M; Purdue A; Fulton E; Grove K; Harney A; Milburn K; Millar R; Mitchell I; Rodgers H; Scanlon S; Coles T; Connor H; Dennett J; Van Berkel A; Barrington-Onslow S; Henderson S; Mehrtens J; Dryburgh J; Tankel A; Braitberg G; O'Bree B; Shepherd K; Vij S; Allsop S; Haji D; Haji K; Vuat J; Bone A; Elderkin T; Orford N; Ragg M; Kelly S; Stewart D; Woodward N; Harjola VP; Okkonen M; Pettilä V; Sutinen S; Wilkman E; Fratzia J; Halkhoree J; Treloar S; Ryan K; Sandford T; Walsham J; Jenkins C; Williamson D; Burrows J; Hawkins D; Tang C; Dimakis A; Holdgate A; Micallef S; Parr M; White H; Morrison L; Sosnowski K; Ramadoss R; Soar N; Wood J; Franks M; Williams A; Hogan C; Song R; Tilsley A; Rainsford D; Wells R; Dowling J; Galt P; Lamac T; Lightfoot D, 2017, 'Potential Impact of the 2016 Consensus Definitions of Sepsis and Septic Shock on Future Sepsis Research', Annals of Emergency Medicine, 70, pp. 553 - 561.e1, http://dx.doi.org/10.1016/j.annemergmed.2017.04.007

Cheung W; Myburgh J; McGuinness S; Chalmers D; Parke R; Blyth F; Seppelt I; Parr M; Hooker C; Blackwell N; DeMonte S; Gandhi K; Kol M; Kerridge I; Nair P; Saunders NM; Saxena MK; Thanakrishnan G; Naganathan V, 2017, 'A cross-sectional survey of Australian and New Zealand public opinion on methods to triage intensive care patients in an influenza pandemic', Critical Care and Resuscitation, 19, pp. 254 - 265.e6, http://dx.doi.org/10.1016/S1441-2772(23)00924-9

Gillies MA; Sander M; Shaw A; Wijeysundera DN; Myburgh J; Aldecoa C; Jammer I; Lobo SM; Pritchard N; Grocott MPW; Schultz MJ; Pearse RM, 2017, 'Current research priorities in perioperative intensive care medicine', Intensive Care Medicine, 43, pp. 1173 - 1186, http://dx.doi.org/10.1007/s00134-017-4848-3

Gotmaker R; Peake SL; Forbes A; Bellomo R, 2017, 'Mortality is Greater in Septic Patients with Hyperlactatemia Than with Refractory Hypotension', Shock, 48, pp. 294 - 300, http://dx.doi.org/10.1097/SHK.0000000000000861

Perner A; Gordon AC; Angus DC; Lamontagne F; Machado F; Russell JA; Timsit JF; Marshall JC; Myburgh J; Shankar-Hari M; Singer M, 2017, 'The intensive care medicine research agenda on septic shock', Intensive Care Medicine, 43, pp. 1294 - 1305, http://dx.doi.org/10.1007/s00134-017-4821-1

Hammond NE; Bellomo R; Gallagher M; Gattas D; Glass P; Mackle D; Micallef S; Myburgh J; Saxena M; Taylor C; Young P; Finfer S, 2017, 'The plasma-lyte 148 v saline (PLUS) study protocol: A multicentre, randomised controlled trial of the effect of intensive care fluid therapy on mortality', Critical Care and Resuscitation, 19, pp. 239 - 246

Patel A; Pieper K; Myburgh JA; Perkovic V; Finfer S; Yang Q; Li Q; Billot L, 2017, 'Reanalysis of the crystalloid versus hydroxyethyl starch trial (CHEST)', New England Journal of Medicine, 377, pp. 298 - 300, http://dx.doi.org/10.1056/NEJMc1703337

Naganathan V; Cheung W; Myburgh J, 2017, 'SURVEY OF AUSTRALIAN AND NEW ZEALAND PUBLIC ON CRITERIA TO TRIAGE PATIENTS IN AN INFLUENZA PANDEMIC', Innovation in Aging, 1, pp. 298 - 298, http://dx.doi.org/10.1093/geroni/igx004.1108

Møller MH; Laake JH; Myburgh JA; Alhazzani W; Perner A, 2017, 'The Magic Bullet in Sepsis or the Inflation of Chance Findings?', Chest, 152, pp. 222 - 223, http://dx.doi.org/10.1016/j.chest.2017.04.181

Rowan KM; Angus DC; Bailey M; Barnato AE; Bellomo R; Canter RR; Coats TJ; Delaney A; Gimbel E; Grieve RD; Harrison DA; Higgins AM; Howe B; Huang DT; Kellum JA; Mouncey PR; Music E; Peake SL; Pike F; Reade MC; Sadique MZ; Singer M; Yealy DM, 2017, 'Early, goal-directed therapy for septic shock - A patient-level meta-analysis', New England Journal of Medicine, 376, pp. 2223 - 2234, http://dx.doi.org/10.1056/NEJMoa1701380

Udy AA; Dulhunty JM; Roberts JA; Davis JS; Webb SAR; Bellomo R; Gomersall C; Shirwadkar C; Eastwood GM; Myburgh J; Paterson DL; Starr T; Paul SK; Lipman J; Peck L; Young H; Boschert C; Fletcher J; Smith J; Nand K; Sara T; Harney A; Rodgers H; Van Haren F; Clarke S; Durham D; Hannan C; Matheson E; Schwartz K; Thomas K; Bone A; Cattigan C; Elderkin T; Salerno T; Cameron R; Ellis K; Hatter S; Sanap M; Soar N; Wood J; Chan K; Heffernan A; Lai NA; Moss C; Sheehy K; Duroux M; Ratcliffe M; Shone S; Warhurst T; Dunlop R; Stuart J; Cooper D; McAllister R; Cheng A; Inskip D; Miller J; Knowles S; Reynolds C; Rudham S; Baker S; Hepburn K; Roberts B; Woods P; Chatterjee I; Smith J; Cullen M; Kong J; Nayyar V; Whitehead C; Leung P; Gilder E; McCarthy L; McGuiness S; Parke R; Benefield K; Chen Y; McArthur C; Newby L; Henderson S; Mehrtens J; Noble S; Chadwick L; Freebain R; Hogan C; Kazemi A; Rust L; Song R; Tilsley A; Williams A; Durning J; Frengley R; La Pine M; McCracken G; Sharma SB; Andrews L; Dinsdale R; Hunt A; Hurford S; Mackle D; Ongley J, 2017, 'Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trial', International Journal of Antimicrobial Agents, 49, pp. 624 - 630, http://dx.doi.org/10.1016/j.ijantimicag.2016.12.022

Hammond NE; Taylor C; Finfer S; Machado FR; An YZ; Billot L; Bloos F; Bozza F; Cavalcanti AB; Correa M; Du B; Hjortrup PB; Li Y; McIntryre L; Saxena M; Schortgen F; Watts NR; Myburgh J, 2017, 'Patterns of intravenous fluid resuscitation use in adult intensive care patients between 2007 and 2014: An international cross-sectional study', PLoS ONE, 12, pp. e0176292, http://dx.doi.org/10.1371/journal.pone.0176292

Fullerton JN; Thompson K; Shetty A; Iredell JR; Lander H; Myburgh JA; Finfer S, 2017, 'New sepsis definition changes incidence of sepsis in the intensive care unit', Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 19, pp. 9 - 13

Fullerton JN; Thompson K; Shetty A; Iredell JR; Lander H; Myburgh JA; Finfer S, 2017, 'New sepsis definition changes incidence of sepsis in the intensive care unit', Critical Care and Resuscitation, 19, pp. 9 - 13.e21, http://dx.doi.org/10.1016/S1441-2772(23)00751-2

Rhodes A; Evans LE; Alhazzani W; Levy MM; Antonelli M; Ferrer R; Kumar A; Sevransky JE; Sprung CL; Nunnally ME; Rochwerg B; Rubenfeld GD; Angus DC; Annane D; Beale RJ; Bellinghan GJ; Bernard GR; Chiche JD; Coopersmith C; De Backer DP; French CJ; Fujishima S; Gerlach H; Hidalgo JL; Hollenberg SM; Jones AE; Karnad DR; Kleinpell RM; Koh Y; Lisboa TC; Machado FR; Marini JJ; Marshall JC; Mazuski JE; McIntyre LA; McLean AS; Mehta S; Moreno RP; Myburgh J; Navalesi P; Nishida O; Osborn TM; Perner A; Plunkett CM; Ranieri M; Schorr CA; Seckel MA; Seymour CW; Shieh L; Shukri KA; Simpson SQ; Singer M; Thompson BT; Townsend SR; Van der Poll T; Vincent JL; Wiersinga WJ; Zimmerman JL; Dellinger RP, 2017, 'Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016', Intensive Care Medicine, 43, pp. 304 - 377, http://dx.doi.org/10.1007/s00134-017-4683-6

Marshall JC; Bosco L; Adhikari NK; Connolly B; Diaz JV; Dorman T; Fowler R; Meyfroidt G; Nakagawa S; Pelosi P; Vincent J-L; Vollman K; Zimmerman J, 2017, 'What is an intensive care unit? A report of the task force of the World Federation of Societies of Intensive and Critical Care Medicine', JOURNAL OF CRITICAL CARE, 37, pp. 270 - 276, http://dx.doi.org/10.1016/j.jcrc.2016.07.015

Taylor CB; Hammond NE; Laba TL; Watts N; Thompson K; Saxena M; Micallef S; Finfer S; Myburgh J, 2017, 'Drivers of choice of resuscitation fluid in the intensive care unit: A discrete choice experiment', Critical Care and Resuscitation, 19, pp. 134 - 141

Young PJ; Bailey MJ; Beasley RW; Freebairn RC; Hammond NE; Haren FM; Harward ML; Henderson SJ; Mackle DM; McArthur CJ; McGuinness SP; Myburgh JA; Saxena MK; Turner A; Webb SAR; Bellomo R, 2017, 'Protocol and statistical analysis plan for the randomised evaluation of active control of temperature versus ordinary temperature management (REACTOR) trial', Critical Care and Resuscitation, 19, pp. 81 - 87

Billot L; Venkatesh B; Myburgh J; Finfer S; Cohen J; Webb S; McArthur C; Joyce C; Bellomo R; Rhodes A; Perner A; Arabi Y; Rajbhandari D; Glass P; Thompson K; Correa M; Harward M, 2017, 'Statistical analysis plan for the adjunctive corticosteroid treatment in critically ill patients with septic shock (Adrenal) trial', Critical Care and Resuscitation, 19, pp. 183 - 191

Thompson K; Hammond N; Eastwood G; Festa M; Glass P; Rajbhandari D; Seppelt I; Taylor C; Watts N; Myburgh J, 2017, 'The Australian and New Zealand intensive care society clinical trials group point prevalence program, 2009-2016', Critical Care and Resuscitation, 19, pp. 88 - 93

Marshall JC, 2017, 'Global Collaboration in Acute Care Clinical Research: Opportunities, Challenges, and Needs.', Crit Care Med, 45, pp. 311 - 320, http://dx.doi.org/10.1097/CCM.0000000000002211

Myburgh J, 2016, 'End of life care in the intensive care unit: Remarks on the Italian situation: REPLY', Journal of Critical Care, 36, pp. 294, http://dx.doi.org/10.1016/j.jcrc.2016.08.013

Perner A; Gordon AC; De Backer D; Dimopoulos G; Russell JA; Lipman J; Jensen JU; Myburgh J; Singer M; Bellomo R; Walsh T, 2016, 'Sepsis: frontiers in diagnosis, resuscitation and antibiotic therapy', Intensive Care Medicine, 42, pp. 1958 - 1969, http://dx.doi.org/10.1007/s00134-016-4577-z

Blanch L; Abillama FF; Amin P; Christian M; Joynt GM; Myburgh J; Nates JL; Pelosi P; Sprung C; Topeli A; Vincent JL; Yeager S; Zimmerman J, 2016, 'Triage decisions for ICU admission: Report from the Task Force of the World Federation of Societies of Intensive and Critical Care Medicine', Journal of Critical Care, 36, pp. 301 - 305, http://dx.doi.org/10.1016/j.jcrc.2016.06.014

Ramanan M; Myburgh J; Finfer S; Bellomo R; Venkatesh B, 2016, 'Publication of secondary analyses from randomized trials in critical care', New England Journal of Medicine, 375, pp. 2105 - 2106, http://dx.doi.org/10.1056/NEJMc1610367

Taylor C; Thompson K; Finfer S; Higgins A; Jan S; Li Q; Liu B; Myburgh J, 2016, 'Hydroxyethyl starch versus saline for resuscitation of patients in intensive care: long-term outcomes and cost-effectiveness analysis of a cohort from CHEST', The Lancet Respiratory Medicine, 4, pp. 818 - 825, http://dx.doi.org/10.1016/S2213-2600(16)30120-5

Roberts JA; Abdul-Aziz MH; Davis JS; Dulhunty JM; Cotta MO; Myburgh J; Bellomo R; Lipman J, 2016, 'Continuous versus intermittent β-lactam infusion in severe sepsis: A meta-analysis of individual patient data from randomized trials', American Journal of Respiratory and Critical Care Medicine, 194, pp. 681 - 691, http://dx.doi.org/10.1164/rccm.201601-0024OC

International Consortium of Investigators for Fairness in Trial Data Sharing ; Devereaux PJ; Guyatt G; Gerstein H; Connolly S; Yusuf S, 2016, 'Toward Fairness in Data Sharing.', N Engl J Med, 375, pp. 405 - 407, http://dx.doi.org/10.1056/NEJMp1605654

Myburgh J; Abillama F; Chiumello D; Dobb G; Jacobe S; Kleinpell R; Koh Y; Martin C; Michalsen A; Pelosi P; Torra LB; Vincent JL; Yeager S; Zimmerman J, 2016, 'End-of-life care in the intensive care unit: Report from the Task Force of World Federation of Societies of Intensive and Critical Care Medicine', Journal of Critical Care, 34, pp. 125 - 130, http://dx.doi.org/10.1016/j.jcrc.2016.04.017

Cotta MO; Dulhunty JM; Roberts JA; Myburgh J; Lipman J, 2016, 'Should β-lactam antibiotics be administered by continuous infusion in critically ill patients? A survey of Australia and New Zealand intensive care unit doctors and pharmacists', International Journal of Antimicrobial Agents, 47, pp. 436 - 438, http://dx.doi.org/10.1016/j.ijantimicag.2016.02.017

Bellomo R; Mårtensson J; Kaukonen KM; Lo S; Gallagher M; Cass A; Myburgh J; Finfer S, 2016, 'Epidemiology of RBC transfusions in patients with severe acute kidney injury: Analysis from the randomized evaluation of normal versus augmented level study', Critical Care Medicine, 44, pp. 892 - 900, http://dx.doi.org/10.1097/CCM.0000000000001518

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