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Preprints

Shanthakumar M; Billot L; Ferreira M, HEalth literacy in Low back Pain – the HELP! media intervention study: A stepped wedge cluster randomised trial, http://dx.doi.org/10.64898/2025.12.11.25342096

Wang X; Ren X; Li Q; Ouyang M; Chen C; Delcourt C; Chen X; Wang J; Robinson T; Arima H; Ma L; Hu X; You C; Li G; Yang J; Lin Y; Billot L; Muñoz-Venturelli P; Martins S; Pontes-Neto OM; Liu L; Chalmers J; Song L; Anderson CS; Investigators TI, Optimizing blood pressure in acute intracerebral hemorrhage: protocol for a prospective individual participant data meta-analysis of the four INTERACT trials, http://dx.doi.org/10.1101/2025.03.03.25323285

Young P; Devaux A; Li Q; Billot L; Davis J; Delaney A; Finfer S; Hammond N; Micallef S; Seppelt I; Venkatesh B; Myburgh JA, Selective digestive tract decontamination in critically ill adults with acute brain injuries: a Post-Hoc analysis of a Randomized Clinical Trial., http://dx.doi.org/10.21203/rs.3.rs-3412001/v1

de Campos TF; Gamble AR; Ferreira GE; Maher CG; Anderson DB; Hutton JM; MacPherson S; Han CS; Sawan M; Harris I; Adie S; Hassett L; Legg C; Van Gelder J; Halliday M; Boogs M; Charteris R; Williams C; Billot L; Fullwood D; Riley-Gibson E; Molineux E; Tambree K; Tchan M; Sharma S; Haynes A; Moujalli J; Wong E; Zadro JR, Stakeholder perceptions of the VIrtual Physiotherapist-led Evaluation of low back pain Referrals to spine surgeons (VIPER) model of care: a qualitative study, http://dx.doi.org/10.1101/2025.10.29.25338508

Liu X; Billot L; Devaux A; Maher C; Lin C; Day RO; Ivers R; Underwood M; McLachlan AJ; Richards B; Finnerup NB; Taing C; Tong K; Jamshidi M; Hassan M; Hamilton M; Atkins E; Ferreira G, Statistical Analysis Plan (SAP) – DREAM: an adaptive, randomised, placebo-controlled trial of duloxetine for reducing leg pain in people with chronic sciatica, http://dx.doi.org/10.64898/2026.07.12.26357883

Lin X; Jiang C; Wang Z; Arima H; Wang X; Billot L; Neal B; Rodgers A; Hillis GS; Patel A; Biostat QLM; Dong J; Du X; Ma C; Anderson CS, Statistical Analysis Plan (SAP): A randomized controlled trial of intensive blood pressure control on cardiovascular risk reduction in patients with atrial fibrillation: the CRAFT trial, http://dx.doi.org/10.1101/2025.06.19.25329849

Liu X; Teng MJ; Billot L; Maher C; Zadro J; Traeger A, Statistical Analysis Plan for RECITAL: a non-inferiority randomised control trial evaluating a virtual fracture clinic compared with in-person care for people with simple fractures, http://dx.doi.org/10.1101/2025.08.07.25333243

Billot L; Gore J; Atherton J; Berry C; Brachmann J; Ganesan A; Hillis G; Jung W; Prasad S; Selvanayagam J, Statistical Analysis Plan for the Cardiac Magnetic Resonance GUIDEd Management of Mild-moderate Left Ventricular Systolic Dysfunction (CMR GUIDE) trial, http://dx.doi.org/10.64898/2026.01.13.26344019

Herbert R; Billot L; Harvey L, Statistical Analysis Plan for the Early & Intensive SCI-MT Trial, http://dx.doi.org/10.31219/osf.io/ms4ef

Billot L; Venkatesh B; Finfer S; Cohen J; Rajbhandari D; Myburgh J; Walsham J, Statistical Analysis Plan for the Fludrocortisone Dose Response Relationship in Septic Shock (FluDReSS) trial, http://dx.doi.org/10.31219/osf.io/hb6f5

Ghosh A; Bhattacharya A; Jha V; Vijayaraghavan BKT; Bassi A; Rajbhandari D; Donaldson L; Billot L; Kunigari M; Hammond N; John O; Joshi R; Myatra SN; Arfin S; Venkatesh B, Statistical Analysis Plan for the HydrOxychloroquine Prophylaxis Evaluation (HOPE) trial, http://dx.doi.org/10.31219/osf.io/uw3ed

Billot L; Chen C; Song L; Lin Y; Liu F; Chen X; Arima H; Bath PM; Ford GA; Robinson T; Sandset EC; Saver JL; Sprigg N; van der Worp B; Yang J; Li G; Anderson CS, Statistical Analysis Plan for the INTEnsive ambulance-delivered blood pressure Reduction in hyper-Acute stroke Trial (INTERACT4), http://dx.doi.org/10.31219/osf.io/qj6u8

Billot L; Song L; Hu X; Ma L; Ouyang M; Chen X; You C; Anderson CS, Statistical Analysis Plan for the INTEnsive care bundle with blood pressure Reduction in Acute Cerebral haemorrhage Trial (INTERACT3), http://dx.doi.org/10.31219/osf.io/m54jc

Billot L; O'Connor D; Maguire B; Schram D; Ma R; Buchbinder R; Maher C; McCaffery K; Traeger A; Albarqouni L; Gorelik A, Statistical Analysis Plan for the MSK DI AF trial, http://dx.doi.org/10.31219/osf.io/prnd2

Billot L; Bompoint S; Ouyang M; Xu L; Wang X; Malavera A; Johnson B; Summers D; Khatri P; Muñoz-Venturelli P; Day D; Sui Y; Song L; Zaidi WAW; Thang NH; Delcourt C; Robinson T; Jan S; Lindley RI; Urrutia VC; Anderson CS, Statistical Analysis Plan for the Optimal Post rTpa-Iv Monitoring in Ischemic Stroke Trial (OPTIMIST), http://dx.doi.org/10.1101/2024.12.17.24319094

Billot L; Song L; Yang P; Liu J; Anderson CS, Statistical Analysis Plan for the second ENhanced Control of Hypertension And Thrombectomy strokE stuDy (ENCHANTED2), http://dx.doi.org/10.31219/osf.io/qkwn9

Billot L; Monaghan H; Wong MG; Perkovic V, Statistical Analysis Plan for the Therapeutic Evaluation of Steroids in IgA Nephropathy Global Study (TESTING), http://dx.doi.org/10.31219/osf.io/d7qrw

Billot L; Wong MG; De Vriese A; Collister D; Flahault A; Mushahar L; Ramachandran R; Skhiri H; Shaman A; Menne J; Gallagher M, Statistical Analysis Plan for the Treatment of Cardiovascular disease with low dose Rivaroxaban in Advanced CKD (TRACK) trial, http://dx.doi.org/10.1101/2025.11.25.25340065


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