By Professor Laurent Billot

Journal articles

Billot L; Venkatesh B; Myburgh J; Finfer S; Cohen J; Webb S; McArthur C; Joyce C; Bellomo R; Rhodes A; Perner A; Arabi Y; Rajbhandari D; Glass P; Thompson K; Correa M; Harward M, 2017, 'Statistical analysis plan for the adjunctive corticosteroid treatment in critically ill patients with septic shock (Adrenal) trial', Critical Care and Resuscitation, 19, pp. 183 - 191

Angell B; Laba T; Lung T; Brown A; Eades S; Usherwood T; Peiris D; Billot L; Hillis G; Webster R; Patel A; Jan S, 2017, 'Healthcare expenditure on Indigenous and non-Indigenous Australians at high risk of cardiovascular disease', International journal for equity in health, 16, pp. 108, http://dx.doi.org/10.1186/s12939-017-0610-2

Muñoz Venturelli P; Robinson T; Lavados PM; Olavarría VV; Arima H; Billot L; Hackett ML; Lim JY; Middleton S; Pontes-Neto O; Peng B; Cui L; Song L; Mead G; Watkins C; Lin RT; Lee TH; Pandian J; de Silva HA; Anderson CS; Munoz Venturelli P, 2016, 'Regional variation in acute stroke care organisation', Journal of the Neurological Sciences, 371, pp. 126 - 130, http://dx.doi.org/10.1016/j.jns.2016.10.026

Coxon K; Chevalier A; Brown J; Clarke E; Billot L; Boufous S; Ivers R; Keay L, 2016, 'Effects of a Safe Transportation Educational Program for Older Drivers on Driving Exposure and Community Participation: A Randomized Controlled Trial', J Am Geriatr Soc, http://dx.doi.org/10.1111/jgs.14550

McEvoy RD; Antic NA; Heeley E; Luo Y; Ou Q; Zhang X; Mediano O; Chen R; Drager LF; Liu Z; Chen G; Du B; McArdle N; Mukherjee S; Tripathi M; Billot L; Li Q; Lorenzi-Filho G; Barbe F; Redline S; Wang J; Arima H; Neal B; White DP; Grunstein RR; Zhong N; Anderson CS, 2016, 'CPAP for prevention of cardiovascular events in obstructive sleep apnea', New England Journal of Medicine, 375, pp. 919 - 931, http://dx.doi.org/10.1056/NEJMoa1606599

Lin CWC; McLachlan AJ; Latimer J; Day RO; Billot L; Koes BW; Maher CG, 2016, 'OPAL: A randomised, placebo-controlled trial of opioid analgesia for the reduction of pain severity in people with acute spinal pain. Trial protocol', BMJ Open, 6, pp. e011278, http://dx.doi.org/10.1136/bmjopen-2016-011278

Zheng D; Sato S; Arima H; Heeley E; Delcourt C; Cao Y; Chalmers J; Anderson CS; Davis S; Huang Y; Lavados P; Neal B; Parsons MW; Lindley R; Morgenstern L; Robinson TG; Stapf C; Tzourio C; Wang JG; Chen S; Chen XY; Cui L; Liu Z; Lu C; Wang J; Wu S; Xu E; Yang Q; Zhang C; Zhang J; Beer R; Schmutzhard E; Redondo P; Kaste M; Soinne L; Tatlisumak T; Wartenberg K; Ricci S; Klijn K; Azevedo E; Chamorro A; Arnold M; Fischer U; Kaul S; Pandian J; Boyini H; Singh S; Rabinstein AA; Estol C; Silva G; Olavarria VV; Simes RJ; Bousser MG; Hankey G; Jamrozik K; Johnston SC; Li S; Bailey K; Cheung T; Chintapatla S; Ducasse E; Erho T; Hata J; Holder B; Knight E; Leroux M; Sassé T; Odgers E; Walsh R; Wolfowicz Z; Chen G; Fuentes S; Peng B; Schneble HM; Wang MX; Billot L; Heritier S; Li Q; Woodward M; Abimbola S; Anderson S; Chan E; Cheng G; Chmielnik P; Leighton S; Liu JY; Rasmussen B; Saxena A; Tripathy S; Armenis M; Baig MA; Naidu B; Starzec G; Steley S; Moles A; Ruiz A; Zimmermann M; Marinho J; Alves S; Angelim R, 2016, 'Estimated GFR and the Effect of Intensive Blood Pressure Lowering after Acute Intracerebral Hemorrhage', American Journal of Kidney Diseases, 68, pp. 94 - 102, http://dx.doi.org/10.1053/j.ajkd.2016.01.020

Carcel C; Sato S; Zheng D; Heeley E; Arima H; Yang J; Wu G; Chen G; Zhang S; Delcourt C; Lavados P; Robinson T; Lindley RI; Wang X; Chalmers J; Anderson CS, 2016, 'Prognostic significance of hyponatremia in acute intracerebral hemorrhage: Pooled analysis of the intensive blood pressure reduction in acute cerebral hemorrhage trial studies', Critical Care Medicine, 44, pp. 1388 - 1394, http://dx.doi.org/10.1097/CCM.0000000000001628

Anderson CS; Robinson T; Lindley RI; Arima H; Lavados PM; Lee TH; Broderick JP; Chen X; Chen G; Sharma VK; Kim JS; Thang NH; Cao Y; Parsons MW; Levi C; Huang Y; Olavarría VV; Demchuk AM; Bath PM; Donnan GA; Martins S; Pontes-Neto OM; Silva F; Ricci S; Roffe C; Pandian J; Billot L; Woodward M; Li Q; Wang X; Wang J; Chalmers J, 2016, 'Low-dose versus standard-dose intravenous alteplase in acute ischemic stroke', New England Journal of Medicine, 374, pp. 2313 - 2323, http://dx.doi.org/10.1056/NEJMoa1515510

Billot L; Corcoran K; McDonald A; Powell-Davies G; Feyer AM; Powell Davies G, 2016, 'Impact Evaluation of a System-Wide Chronic Disease Management Program on Health Service Utilisation: A Propensity-Matched Cohort Study', PLoS Medicine, 13, pp. e1002035, http://dx.doi.org/10.1371/journal.pmed.1002035

Bellomo R; Mårtensson J; Kaukonen KM; Lo S; Gallagher M; Cass A; Myburgh J; Finfer S, 2016, 'Epidemiology of RBC transfusions in patients with severe acute kidney injury: Analysis from the randomized evaluation of normal versus augmented level study', Critical Care Medicine, 44, pp. 892 - 900, http://dx.doi.org/10.1097/CCM.0000000000001518

Bellomo R; Mårtensson J; Lo S; Kaukonen KM; Cass A; Gallagher M, 2016, 'Femoral Access and Delivery of Continuous Renal Replacement Therapy Dose', Blood Purification, 41, pp. 11 - 17, http://dx.doi.org/10.1159/000439581

Webster R; Patel A; Selak V; Billot L; Bots ML; Brown A; Bullen C; Cass A; Crengle S; Raina Elley C; Grobbee DE; Neal B; Peiris D; Poulter N; Prabhakaran D; Rafter N; Stanton A; Stepien S; Thom S; Usherwood T; Wadham A; Rodgers A, 2016, 'Effectiveness of fixed dose combination medication ('polypills') compared with usual care in patients with cardiovascular disease or at high risk: A prospective, individual patient data meta-analysis of 3140 patients in six countries', International Journal of Cardiology, 205, pp. 147 - 156, http://dx.doi.org/10.1016/j.ijcard.2015.12.015

Zheng D; Arima H; Sato S; Gasparrini A; Heeley E; Delcourt C; Lo S; Huang Y; Wang J; Stapf C; Robinson T; Lavados P; Chalmers J; Anderson CS; Li Q; Neal B; Billot L; Woodward M, 2016, 'Low ambient temperature and intracerebral hemorrhage: The INTERACT2 study', PLoS ONE, 11, pp. e0149040, http://dx.doi.org/10.1371/journal.pone.0149040

Mathieson S; Billot L; Maher CG; McLachlan AJ; Latimer J; Koes BW; Hancock MJ; Harris I; Day RO; Pik J; Jan S; Lin CWC, 2016, 'PRECISE - pregabalin in addition to usual care: Statistical analysis plan', Trials, 17, pp. 53, http://dx.doi.org/10.1186/s13063-016-1174-y

Sato S; Delcourt C; Zhang S; Arima H; Heeley E; Zheng D; Al-Shahi Salman R; Stapf C; Tzourio C; Robinson T; Lindley RI; Chalmers J; Anderson CS, 2016, 'Determinants and prognostic significance of hematoma sedimentation levels in acute intracerebral hemorrhage', Cerebrovascular Diseases, 41, pp. 80 - 86, http://dx.doi.org/10.1159/000442532

Heeley E; Billot L; Anderson CS; Antic NA; Neal B; McEvoy RD, 2016, 'Statistical analysis plan for the Sleep Apnea cardioVascular Endpoints study: An international randomised controlled trial to determine whether continuous positive airways pressure treatment for obstructive sleep apnea in patients with CV disease prevents secondary cardiovascular events', International Journal of Stroke, 11, pp. 148 - 150, http://dx.doi.org/10.1177/1747493015607504

Sato S; Heeley E; Arima H; Delcourt C; Hirakawa Y; Pamidimukkala V; Li Z; Tao Q; Xu Y; Hennerici MG; Robinson T; Tzourio C; Lindley RI; Chalmers J; Anderson CS, 2015, 'Higher mortality in patients with right hemispheric intracerebral haemorrhage: INTERACT1 and 2', Journal of Neurology, Neurosurgery and Psychiatry, 86, pp. 1319 - 1323, http://dx.doi.org/10.1136/jnnp-2014-309870

Sato S; Arima H; Heeley E; Hirakawa Y; Delcourt C; Lindley RI; Robinson T; Huang Y; Morgenstern L; Stapf C; Wang J; Chalmers J; Anderson CS, 2015, 'Off-Hour admission and outcomes in patients with acute intracerebral hemorrhage in the INTERACT2 trial', Cerebrovascular Diseases, 40, pp. 114 - 120, http://dx.doi.org/10.1159/000434690

Saxena MK; Taylor C; Billot L; Bompoint S; Gowardman J; Roberts JA; Lipman J; Myburgh J, 2015, 'The effect of paracetamol on core body temperature in acute traumatic brain injury: A randomised, controlled clinical trial', PLoS ONE, 10, pp. e0144740, http://dx.doi.org/10.1371/journal.pone.0144740

Patel A; Cass A; Peiris D; Usherwood T; Brown A; Jan S; Neal B; Hillis GS; Rafter N; Tonkin A; Webster R; Billot L; Bompoint S; Burch C; Burke H; Hayman N; Molanus B; Reid CM; Shiel L; Togni S; Rodgers A, 2015, 'A pragmatic randomized trial of a polypill-based strategy to improve use of indicated preventive treatments in people at high cardiovascular disease risk', European Journal of Preventive Cardiology, 22, pp. 920 - 930, http://dx.doi.org/10.1177/2047487314530382

Finfer S; Chittock D; Li Y; Foster D; Dhingra V; Bellomo R; Cook D; Dodek P; Hebert P; Henderson W; Heyland D; Higgins A; McArthur C; Mitchell I; Myburgh J; Robinson B; Ronco J; Blair D; Norton R; Potter J; McDonald E; Peto R; Sandercock P; Sprung C; Young JD; Li Q; Bompoint S; Billot L; Crampton L; Darcy F; Jayne K; Kumarasinghe V; Little L; McEvoy S; MacMahon S; Pandey S; Ryan S; Shukla R; Vijayan B; Atherton S; Bell J; Hadfield L; Hourigan C; Newby L; Simmonds C; Buhr H; Eccleston M; McGuinness S; Parke R; Bates S; Goldsmith D; Mercer I; O’Sullivan K; Gazzard R; Hill D; Tauschke C; Ghelani D; Nand K; Reece G; Sara T; Elliott S; Ernest D; Hamilton A; Ashley R; Bailey A; Crowfoot E; Gissane J; Ranse J; Whiting J; Douglas K; Milliss D; Tan J; Wong H; Blythe D; Palermo A; Hardie M; Harrigan P; McFadyen B; Micallef S; Parr M; Boase A; Tai J; Williams A; Cole L; Seppelt I; Weisbrodt L; Whereat S; Flanagan A; Liang J; Bass F; Campbell M; Hammond N; Nicholson L; Shehabi Y; Foote J; Peake S; Williams P; Deans R; Fourie C; Lassig-Smith M, 2015, 'Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study', Intensive Care Medicine, 41, pp. 1037 - 1047, http://dx.doi.org/10.1007/s00134-015-3757-6

Muñoz-Venturelli P; Arima H; Lavados P; Brunser A; Peng B; Cui L; Song L; Billot L; Boaden E; Hackett ML; Heritier S; Jan S; Middleton S; Olavarría VV; Lim JY; Lindley RI; Heeley E; Robinson T; Pontes-Neto O; Natsagdorj L; Lin RT; Watkins C; Anderson CS; Woodward M, 2015, 'Head Position in Stroke Trial (HeadPoST) - sitting-up vs lying-flat positioning of patients with acute stroke: Study protocol for a cluster randomised controlled trial', Trials, 16, pp. 256, http://dx.doi.org/10.1186/s13063-015-0767-1

Nguyen Viet N; Yunus F; Nguyen Thi Phuong A; Dao Bich V; Damayanti T; Wiyono WH; Billot L; Jakes RW; Kwon N, 2015, 'The prevalence and patient characteristics of chronic obstructive pulmonary disease in non-smokers in Vietnam and Indonesia: An observational survey', Respirology, 20, pp. 602 - 611, http://dx.doi.org/10.1111/resp.12507

Priglinger M; Arima H; Anderson C; Krause M; Chalmers J; Huang Y; Wang JG; Bath P; Davis S; Kim J; Lindley R; Neal B; Morgenstern LB; MacMahon S; Woodward M; Butcher K; Chambers B; Donnan G; Levi C; Parsons MW; Dorsch N; Huang Y; Wang JG; Lu C; Chen S; Jiang JD; Liu Z; Zhang J; Kong L; Song Y; Wang Z; Wang W; Wu F; Yuan Y; Kim JS; Kim J; Simes J; Hankey G; Jamrozik K; Johnston S; Shunwei L; Skulina C; Peng B; Billot L; Li Q; Su S; Heritier S; Heeley E; Capper H; Chisholm J; Currie R; Fathers J; Hackett M; Homewood S; Jane K; Jones K; Leksuwat S; Mullane B; Pandey S; Patel A; Quilkey A; Scott J; Starzec G; Wadham A; Zeckendorf S; Han D; Ying S; Xu W; Zhang LJ; Huang Q; Li Y; Yan L; Kyung S, 2015, 'No relationship of lipid-lowering agents to hematoma growth: Pooled analysis of the intensive blood pressure reduction in acute cerebral hemorrhage trials studies', Stroke, 46, pp. 857 - 859, http://dx.doi.org/10.1161/STROKEAHA.114.007664

Li S; Wu Y; Du X; Li X; Patel A; Peterson ED; Turnbull F; Lo S; Billot L; Laba T; Gao R, 2015, 'Rational and design of a stepped-wedge cluster randomized trial evaluating quality improvement initiative for reducing cardiovascular events among patients with acute coronary syndromes in resource-constrained hospitals in China', American Heart Journal, 169, pp. 349 - 355, http://dx.doi.org/10.1016/j.ahj.2014.12.005

Saxena MK; Taylor C; Hammond N; Young P; Mysore J; Billot L; Myburgh A; Myburgh J, 2015, 'A multicentre audit of temperature patterns after traumatic brain injury', Critical Care and Resuscitation, 17, pp. 129 - 134

Arima H; Heeley E; Delcourt C; Hirakawa Y; Wang X; Woodward M; Robinson T; Stapf C; Parsons M; Lavados PM; Huang Y; Wang J; Chalmers J; Anderson CS, 2015, 'Optimal achieved blood pressure in acute intracerebral hemorrhage: INTERACT2', Neurology, 84, pp. 464 - 471, http://dx.doi.org/10.1212/WNL.0000000000001205

Zoungas S; Chalmers J; Neal B; Billot L; Li Q; Biostat M; Hirakawa Y; Arima H; Monaghan H; Joshi R; Colagiuri S; Cooper ME; Glasziou P; Grobbee D; Hamet P; Harrap S; Heller S; Lisheng L; Mancia G; Marre M; Matthews DR; Mogensen CE; Perkovic V; Poulter N; Rodgers A; Williams B; MacMahon S; Patel A; Woodward M, 2014, 'Follow-up of blood-pressure lowering and glucose control in type 2 diabetes', New England Journal of Medicine, 371, pp. 1392 - 1406, http://dx.doi.org/10.1056/NEJMoa1407963

Wang AY; Bellomo R; Ninomiya T; Lo S; Cass A; Jardine M; Gallagher M, 2014, 'Angiotensin-converting enzyme inhibitor usage and acute kidney injury: A secondary analysis of RENAL study outcomes', Nephrology, 19, pp. 617 - 622, http://dx.doi.org/10.1111/nep.12284

Hammond NE; Billot L; Finfer S; Myburgh J, 2014, 'Individual patient data comparative analysis of hydroxyethyl starch 130/0.4 v 4% albumin for fluid resuscitation in critically ill patients: Statistical analysis plan', Critical Care and Resuscitation, 16, pp. 206 - 213

Saxena MK; Hammond N; Myburgh J, 2014, 'Individual patient data meta-analysis of hydroxyethyl starch 130/0.4-0.42 versus crystalloid for fluid resuscitation in patients with severe sepsis: A statistical analysis plan', Critical Care and Resuscitation, 16, pp. 96 - 115, http://search.informit.com.au/documentSummary;res=IELHEA;dn=312745606203494

Du X; Gao R; Turnbull F; Wu Y; Rong Y; Lo S; Billot L; Hao Z; Ranasinghe I; Iedema R; Kong L; Hu D; Lin S; Shen W; Huang D; Yang Y; Ge J; Han Y; Lv S; Ma A; Gao W; Patel A, 2014, 'Hospital quality improvement initiative for patients with acute coronary syndromes in China a cluster randomized, controlled trial', Circulation: Cardiovascular Quality and Outcomes, 7, pp. 217 - 226, http://dx.doi.org/10.1161/CIRCOUTCOMES.113.000526

Jun M; Bellomo R; Cass A; Gallagher M; Lo S; Lee J, 2014, 'Timing of renal replacement therapy and patient outcomes in the randomized evaluation of normal versus augmented level of replacement therapy study', Critical Care Medicine, 42, pp. 1756 - 1765, http://dx.doi.org/10.1097/CCM.0000000000000343

Webster R; Patel A; Billot L; Cass A; Burch C; Neal B; Usherwood T; Thom S; Poulter N; Stanton A; Bots ML; Grobbee DE; Prabhakaran D; Reddy KS; Field J; Bullen C; Elley CR; Selak V; Rafter N; Wadham A; Berwanger O; Rodgers A, 2013, 'Prospective meta-analysis of trials comparing fixed dose combination based care with usual care in individuals at high cardiovascular risk: The SPACE Collaboration', International Journal of Cardiology, 170, pp. 30 - 35, http://dx.doi.org/10.1016/j.ijcard.2013.10.007

Hackett ML; Carter G; Crimmins D; Clarke T; Arblaster L; Billot L; Mysore J; Sturm J, 2013, 'ImProving Outcomes after STroke (POST): Results from the randomized clinical pilot trial', International Journal of Stroke, 8, pp. 707 - 710, http://dx.doi.org/10.1111/j.1747-4949.2012.00913.x

Zhang J; Liu G; Arima H; Li Y; Cheng G; Shiue I; Lv L; Wang H; Zhang C; Zhao J; Anderson CS, 2013, 'Incidence and risks of subarachnoid hemorrhage in China', Stroke, 44, pp. 2891 - 2893, http://dx.doi.org/10.1161/STROKEAHA.113.002599

Land MA; Christoforou A; Downs S; Webster J; Billot L; Li M; Peña-Rosas JP; Neal B, 2013, 'Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders', Cochrane Database of Systematic Reviews, 2013, http://dx.doi.org/10.1002/14651858.CD010734

Thom S; Poulter N; Field J; Patel A; Prabhakaran D; Stanton A; Grobbee DE; Bots ML; Reddy KS; Cidambi R; Bompoint S; Billot L; Rodgers A, 2013, 'Effects of a fixed-dose combination strategy on adherence and risk factors in patients with or at high risk of CVD: The UMPIRE randomized clinical trial', JAMA, 310, pp. 918 - 929, http://dx.doi.org/10.1001/jama.2013.277064

Williams CM; Maher CG; Latimer J; McLachlan AJ; Hancock MJ; Day RO; Billot L; Lin CWC, 2013, 'PACE - the first placebo controlled trial of paracetamol for acute low back pain: Statistical analysis plan', Trials, 14, http://dx.doi.org/10.1186/1745-6215-14-248

Finfer S; Billot L, 2013, 'Managing blood glucose in critically ill patients with or without diabetes', Critical Care, 17, http://dx.doi.org/10.1186/cc12591

Cooper DJ; Myburgh J; Heritier S; Finfer S; Bellomo R; Billot L; Murray L; Vallance S, 2013, 'Albumin resuscitation for traumatic brain injury: Is intracranial hypertension the cause of increased mortality?', Journal of Neurotrauma, 30, pp. 512 - 518, http://dx.doi.org/10.1089/neu.2012.2573

Gattas DJ; Dan A; Myburgh J; Billot L; Lo S; Finfer S, 2013, 'Fluid resuscitation with 6 % hydroxyethyl starch (130/0.4 and 130/0.42) in acutely ill patients: Systematic review of effects on mortality and treatment with renal replacement therapy', Intensive Care Medicine, 39, pp. 558 - 568, http://dx.doi.org/10.1007/s00134-013-2840-0

Bellomo R; Lipcsey M; Calzavacca P; Haase M; Haase-Fielitz A; Licari E; Tee A; Cole L; Cass A; Finfer S; Gallagher M; Lee J; Lo S; McArthur C; McGuinness S; Myburgh J; Scheinkestel C, 2013, 'Early acid-base and blood pressure effects of continuous renal replacement therapy intensity in patients with metabolic acidosis', Intensive Care Medicine, 39, pp. 429 - 436, http://dx.doi.org/10.1007/s00134-012-2800-0

Guidet B, 2013, 'Hydroxyethyl Starch or Saline in Intensive Care', NEW ENGLAND JOURNAL OF MEDICINE, 368, pp. 774 - 774, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000315095800018&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Raghunathan K; Shaw A, 2013, 'Hydroxyethyl Starch or Saline in Intensive Care', NEW ENGLAND JOURNAL OF MEDICINE, 368, pp. 774 - 775, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000315095800019&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Thomas E; Bhurawala H; Liu A, 2013, 'Medication for attention deficit-hyperactivity disorder and criminality [5]', New England Journal of Medicine, 368, pp. 775 - 776, http://dx.doi.org/10.1056/NEJMc1215531

Myburgh JA; Finfer S; Billot L, 2013, 'The authors reply', New England Journal of Medicine, 368, pp. 775, http://dx.doi.org/10.1056/NEJMc1215977

Anderson CS; Heeley E; Huang Y; Wang J; Stapf C; Delcourt C; Lindley R; Robinson T; Lavados P; Neal B; Hata J; Arima H; Parsons M; Li Y; Wang J; Heritier S; Li Q; Woodward M; Simes RJ; Davis SM; Chalmers J, 2013, 'Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage', New England Journal of Medicine, 368, pp. 2355 - 2365, http://dx.doi.org/10.1056/NEJMoa1214609

Harris IA; Day RO, 2013, 'PRECISE - pregabalin in addition to usual care for sciatica: study protocol for a randomised controlled trial', Trials, 14, pp. 213, http://dx.doi.org/10.1186/1745-6215-14-213

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