Select Publications
Journal articles
1999, 'Antisense oligonucleotides to class III B-tubulin sensitise drug-resistant cells to Taxol.', British Journal of Cancer, pp. 1020 - 1025
,1998, 'In Vitro effects of MYCN sense and antisense expression in MYCN-amplified human neuroblastoma cells', Anticancer Research, pp. 1793 - 1798
,1998, 'P-glycoprotein-mediated methotrexate resistance in CCRF-CEM sublines deficient in Methotrexate accumulation due to a point mutation in the reduced folate carrier gene', International Journal of Cancer, pp. 176 - 181
,1997, 'The role of multidrug resistance-associated protein (MRP) expression in multidrug resistance', Anti-Cancer Drugs, 8, pp. 17 - 25, http://dx.doi.org/10.1097/00001813-199701000-00002
,1997, 'EVIDENCE THAT THE N-MYC ONCOGENE REGULATES MRP GENE EXPRESSION IN NEUROBLASTOMA', European Journal of Cancer, pp. 1911 - 1916
,1997, 'TAXOL-RESISTANT EPITHELIAL OVARIAN TUMORS ARE ASSOCIATED WITH ALTERED EXPRESSION OF SPECIFIC {BETA}-TUBLIN ISOTYPES', Journal of Clinical Investigation, 100, pp. 1282 - 1293
,1996, 'MDR1 and multidrug resistance-associated protein (MRP) gene expression in epithelial ovarian tumors', Cancer Letters, 102, pp. 7 - 16, http://dx.doi.org/10.1016/0304-3835(96)04143-2
,1996, 'Involvement of MDR1 P-Glycoprotein in multifactorial resistance to methotrexate', International Journal of Cancer, pp. 613 - 619
,1995, 'An assay for the determination of reduced methotrexate accumulation in cells displaying limited viability in vitro', Cancer Letters, pp. 49 - 55
,1994, 'N-myc gene amplification in neuroblastoma determined by the polymerase chain reaction.', Progress in clinical and biological research, 385, pp. 27 - 33
,1993, 'Determination of n-myc gene amplification in neuroblastoma by differential polymerase chain reaction', Molecular and Cellular Probes, 7, pp. 227 - 234, http://dx.doi.org/10.1006/mcpr.1993.1033
,1993, 'Karyotypic analysis of CCRF-CEM and drug-resistant cell lines with stable and unstable ploidy', Cancer Genetics and Cytogenetics, 66, pp. 54 - 62, http://dx.doi.org/10.1016/0165-4608(93)90149-G
,1993, 'Resistance to Tetracycline, a Hydrophilic Antibiotic, Is Mediated by P-Glycoprotein in Human Multidrug-Resistant Cells', Biochemical and Biophysical Research Communications, 190, pp. 79 - 85, http://dx.doi.org/10.1006/bbrc.1993.1013
,1992, 'Association of N‐myc amplification with neuroblastoma: The Australian and New Zealand experience', Journal of Paediatrics and Child Health, 28, pp. 58 - 63, http://dx.doi.org/10.1111/j.1440-1754.1992.tb02619.x
,1991, 'Characterization of Mechanisms Mediating Drug Resistance in Human Leukemic Cells Selected with High Concentration Methotrexate', Pteridines, 3, pp. 119 - 121, http://dx.doi.org/10.1515/pteridines.1991.3.12.119
,1991, 'Reduced drug accumulation as the mechanism of extreme clinical resistance to methotrexate in the human T‐cell leukemia xenograft, LALW‐2', Cancer, 68, pp. 981 - 987, http://dx.doi.org/10.1002/1097-0142(19910901)68:5<981::AID-CNCR2820680512>3.0.CO;2-W
,1991, 'Two classes of single-stranded regions evident in deproteinized preparations of replicating DNA isolated from mammalian cells', Experimental Cell Research, 192, pp. 639 - 642, http://dx.doi.org/10.1016/0014-4827(91)90087-B
,1990, 'Phenotypic and cytogenetic analysis of atypical multidrug resistance in human leukaemic cells selected with methotrexate at high concentration', Cancer Letters, 51, pp. 193 - 201, http://dx.doi.org/10.1016/0304-3835(90)90102-4
,1989, 'Atypical Multidrug Resistance in a Therapy-induced Drug-resistant Human Leukemia Cell Line (LALW-2): Resistance to Vinca Alkaloids Independent of P-Glycoprotein', Cancer Research, 49, pp. 5281 - 5287
,1989, 'Resistance to drugs associated with the multidrug resistance phenotype following selection with high-concentration methotrexate', Journal of the National Cancer Institute, 81, pp. 1250 - 1254, http://dx.doi.org/10.1093/jnci/81.16.1250
,1986, '2-STAGE INCORPORATION OF THYMIDINE TRIPHOSPHATE INTO MAMMALIAN DNA AS INDICATED BY CHROMATOGRAPHY ON BENZOYLATED DEAE-CELLULOSE', JOURNAL OF CHROMATOGRAPHY, 382, pp. 127 - 134, http://dx.doi.org/10.1016/S0378-4347(00)83511-2
,1986, 'Two-stage incorporation of thymidine triphosphate into mammalian DNA as indicated by chromatography on benzoylated DEAE-cellulose', Journal of Chromatography B: Biomedical Sciences and Applications, 382, pp. 135 - 145, http://dx.doi.org/10.1016/S0378-4347(00)83512-4
,1986, 'Two-stage incorporation of thymidine triphosphate into mammalian DNA as indicated by chromatography on benzoylated DEAE-cellulose', Journal of Chromatography - Biomedical Applications, Vol. 382, pp. 127 - 134
,Conference Papers
2021, 'Development of siRNA-loaded lipid nanoparticles targeting long non-coding RNA LINC01257 as a novel and safe therapeutic approach for paediatric acute myeloid leukaemia', in MOLECULAR CANCER THERAPEUTICS, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1535-7163.TARG-21-P143
,2020, 'NANOPARTICLE DELIVERY OF DOXORUBICIN FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 286 - 286, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100048&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2020, 'Abstract 1442: Identifying the molecular basis by which βIII-tubulin promotes tumor cell survival and drug resistance in non-small cell lung cancer', in Cancer Research, American Association for Cancer Research (AACR), pp. 1442 - 1442, http://dx.doi.org/10.1158/1538-7445.am2020-1442
,2020, 'Development and Biological Optimization of Star-Shaped Polymeric Nanoparticles for the Delivery of Therapeutic siRNA to Lung Cancer Cells In Vitro and In Vivo', in MOLECULAR THERAPY, CELL PRESS, ELECTR NETWORK, pp. 347 - 348, presented at 23rd Annual Meeting of the American-Society-for-Gene-and-Cell-Therapy, ELECTR NETWORK, 12 May 2020 - 15 May 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000530089301322&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2019, 'Multi-user immersive virtual reality prototype for collaborative visualization of microscopy image data', in Spencer SN (ed.), Proceedings - VRCAI 2019: 17th ACM SIGGRAPH International Conference on Virtual-Reality Continuum and its Applications in Industry, Association for Computing Machinery (ACM), AUSTRALIA, Brisbane, pp. 1 - 2, presented at Proceedings of the 17th International Conference on Virtual-Reality Continuum and its Applications in Industry, AUSTRALIA, Brisbane, 17 November 2019 - 20 November 2019, http://dx.doi.org/10.1145/3359997.3365730
,2019, 'Abstract 3224: Copper homeostasis: A new player in anti-tumor immune response', in Cancer Research, American Association for Cancer Research (AACR), pp. 3224 - 3224, http://dx.doi.org/10.1158/1538-7445.am2019-3224
,2019, 'Abstract 3435: Targeting AKT activity inhibits MYCN and sensitizes neuroblastoma to chemotherapeutic agents', in Molecular and Cellular Biology / Genetics, American Association for Cancer Research, pp. 3435 - 3435, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-3435
,2018, 'Precision medicine: High-throughput 3D bioprinting of embedded multicellular cancer spheroids', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, IL, Chicago, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), IL, Chicago, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-5022
,2017, 'Triggering cellular signalling processes with novel macromolecular hydrogen sulfide donors', in ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, CA, San Francisco, presented at 253rd National Meeting of the American-Chemical-Society (ACS) on Advanced Materials, Technologies, Systems, and Processes, CA, San Francisco, 02 April 2017 - 06 April 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000430569107588&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2017, 'High throughput kinase inhibitor screen reveals novel inhibitor combinations acting in synergy with TUBB3/beta III-tubulin suppression in non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 01 April 2017 - 05 April 2017, http://dx.doi.org/10.1158/1538-7445.AM2017-4037
,2017, 'Structural domains of ss III-Tubulin regulate multiple stress responses and influence cell growth and survival in glucose-deprived non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 01 April 2017 - 05 April 2017, http://dx.doi.org/10.1158/1538-7445.AM2017-5484
,2016, 'Dextran-Catechin conjugate: An anticancer nano-modified natural compound targeting copper metabolism in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, LA, New Orleans, presented at 107th Annual Meeting of the American-Association-of-Cancer-Research (AACR), LA, New Orleans, 16 April 2016 - 20 April 2016, http://dx.doi.org/10.1158/1538-7445.AM2016-1340
,2015, 'Discovery of a small molecule TUBB3/beta III-tubulin modulator in lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-3660
,2014, 'Acquired drug resistance by decrease of sialylated glycans on acute lymphoblastic leukemia cell-membrane glycoproteins', in GLYCOBIOLOGY, OXFORD UNIV PRESS INC, HI, Honolulu, pp. 1217 - 1217, presented at Joint Meeting of the Society-for-Glycobiology (SFG) and the Japanese-Society-of-Carbohydrate-Research (JSCR), HI, Honolulu, 16 November 2014 - 19 November 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344670300365&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2014, 'Design and Synthesis of Novel PEGylated Star Nanoparticles as Delivery Agents for Short-Interfering RNA (siRNA) to Pancreatic Cancer Cells', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1416 - 1416, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344362600356&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2014, 'beta III-Tubulin and cell survival: Novel role in endoplasmic reticulum stress and autophagy in non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, San Diego, presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-326
,2014, 'beta III-tubulin is required for the tumorigenic phenotype and resistance to anoikis via the PTEN/AKT signaling axis in non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, San Diego, presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-2076
,2014, 'Stathmin regulates cell migration, invasion and transendothelial migration via RhoA activation in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, San Diego, presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-4987
,2013, 'Lgr4-Mediated Potentiation Of Wnt/beta-Catenin Signaling Promotes MLL Leukemogenesis Via An Rspo3/Wnt3a-Gnaq Pathway In Leukemic Stem Cells', in BLOOD, AMER SOC HEMATOLOGY, LA, New Orleans, presented at 55th Annual Meeting of the American-Society-of-Hematology, LA, New Orleans, 07 December 2013 - 10 December 2013, http://dx.doi.org/10.1182/blood.V122.21.887.887
,2013, 'beta III-Tubulin is a Novel Therapeutic Target for the Treatment of Pancreatic Cancer', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1381 - 1381, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000330468400204&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2013, 'Inhibition of beta III-Tubulin Using a Novel Nanoparticle-siRNA Approach Sensitizes Pancreatic Cancer Cells to Chemotherapy', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1385 - 1385, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000330468400222&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2013, 'beta III-tubulin is a novel therapeutic target for the treatment of pancreatic cancer', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, pp. 12 - 12, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000324106900022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2013, 'Linc367, a novel long intergenic noncoding RNA, up-regulates N-Myc gene expression and neuroblastoma cell proliferation', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, NETHERLANDS, Amsterdam, pp. S356 - S356, presented at European Cancer Congress 2013 - 17th ECCO / 38th ESMO / 32nd ESTRO, NETHERLANDS, Amsterdam, 27 September 2013 - 01 October 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000326843602302&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2012, 'Biodegradable and acid labile dextran-based nanoparticles for doxorubicin delivery', in ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, PA, Philadelphia, presented at 244th National Fall Meeting of the American-Chemical-Society (ACS), PA, Philadelphia, 19 August 2012 - 23 August 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000324621808165&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2011, 'TARGETING DRUG RESISTANCE IN LUNG CANCER', in JOURNAL OF GENE MEDICINE, WILEY-BLACKWELL, AUSTRALIA, Univ Melbourne, Bio21 Inst, Parkville, pp. 415 - 416, presented at 7th Biennial Meeting of the Australasian-Gene-Therapy-Society, AUSTRALIA, Univ Melbourne, Bio21 Inst, Parkville, 04 May 2011 - 06 May 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000297950900015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2010, 'Abstract 4418: ENMD-1198, a new microtubule-targeting agent with potent anti-vascular properties', in Cancer Research, American Association for Cancer Research (AACR), pp. 4418 - 4418, http://dx.doi.org/10.1158/1538-7445.am10-4418
,2010, 'Abstract 5141: Stathmin mediates neuroblastoma migration and invasion via regulation of the actin network', in Cancer Research, American Association for Cancer Research (AACR), pp. 5141 - 5141, http://dx.doi.org/10.1158/1538-7445.am10-5141
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