Select Publications
Conference Papers
2010, 'Abstract LB-368: III-tubulin knockdown in endothelial cells increases the antivascular activity of chemotherapeutic drugs', in Cancer Research, American Association for Cancer Research (AACR), http://dx.doi.org/10.1158/1538-7445.am10-lb-368
,2010, 'beta III-Tubulin regulates expression of proteins involved in tumorigenesis and metastasis in non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209823904149&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2010, 'beta III-Tubulin regulates expression of proteins involved in tumorigenesis and metastasis in non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM10-5026
,2010, 'Molecular and functional alterations associated with repression of tumor suppressor p16INK4a during immortalization of human endothelial cells', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM10-1110
,2009, 'Abstract A156: Mechanisms of resistance to Aurora kinase B inhibitors in leukemia: Development and characterization of in vitro models', in Molecular Cancer Therapeutics, American Association for Cancer Research (AACR), pp. A156 - A156, http://dx.doi.org/10.1158/1535-7163.targ-09-a156
,2009, 'Mechanisms of resistance to Aurora kinase B inhibitors in leukemia: Development and characterization of in vitro models', in MOLECULAR CANCER THERAPEUTICS, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1535-7163,TARG-09-A156
,2008, 'Development of siRNA-Polymer Conjugates and Polyplexes', Melbourne, Australia, presented at 30th Australasian Polymer Symposium, Melbourne, Australia, 30 November 2008 - 04 December 2008
,2008, 'The role of the estrogen-responsive B box protein (EBBP) in cancer cell cycle progression', in EJC SUPPLEMENTS, PERGAMON-ELSEVIER SCIENCE LTD, FRANCE, Lyon, pp. 95 - 95, presented at 20th Meeting of the European-Association-for-Cancer-Research, FRANCE, Lyon, 05 July 2008 - 08 July 2008, http://dx.doi.org/10.1016/S1359-6349(08)71542-8
,2007, 'ENMD-1198 in combination with vincristine shows synergistic activity in leukemia cells and prolonged mouse survival in human leukemia xenografts', in Broze G (ed.), Blood, American Society of Hematology, USA, pp. 859 - 859, presented at 49th Annual Meeting of the American-Society-of-Hematology, Atlanta, Georgia USA, 08 December 2007 - 11 December 2007
,2007, 'ENMD-1198 in combination with vincristine shows synergistic activity in leukemia cells and prolonged mouse survival in human leukemia xenografts', in BLOOD, AMER SOC HEMATOLOGY, GA, Atlanta, pp. 263A - 263A, presented at 49th Annual Meeting of the American-Society-of-Hematology, GA, Atlanta, 08 December 2007 - 11 December 2007, http://dx.doi.org/10.1182/blood.V110.11.859.859
,2006, 'Characterization of a novel regulator of the retinoid signal: The estrogen-responsive B box protein.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454608804357&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2004, 'Tropomyosin antibodies identify functionally distinct populations of actin filaments', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, DC, Washington, pp. 143A - 143A, presented at Annual Meeting of the American-Society-for-Cell-Biology, DC, Washington, 04 December 2004 - 08 December 2004, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000224648801136&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2002, 'Acquired beta-tubulin mutations affecting microtubule stability and drug binding', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, CALIFORNIA, SAN FRANCISCO, pp. 463A - 463A, presented at 42nd Annual Meeting of the American-Society-for-Cell-Biology, CALIFORNIA, SAN FRANCISCO, 14 December 2002 - 18 December 2002, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000179569102604&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,Conference Posters
2018, 'Visual microscope for massive genomics datasets, expanded perception and interaction', Vancouver, Canada, Vol. 1, pp. 1 - 2, presented at SIGGRAPH 2018, Vancouver, Canada, 12 August 2018 - 16 August 2018, http://dx.doi.org/10.1145/3230744.3230745
,Conference Abstracts
2023, 'Abstract B134: Targeting Philadelphia chromosome-like acute lymphoblastic leukemia with a novel CRLF2 antibody fragment-drug conjugate', in Molecular Cancer Therapeutics, American Association for Cancer Research (AACR), Vol. 22, pp. B134 - B134, http://dx.doi.org/10.1158/1535-7163.targ-23-b134
,2020, 'A Novel Engineered Single-Chain Antibody Fragment for Targeting Pediatric Philadelphia Chromosome-like Acute Lymphoblastic Leukemia', in BLOOD, AMER SOC HEMATOLOGY, ELECTR NETWORK, Vol. 136, presented at 62nd Annual Meeting of the American-Society-of-Hematology (ASH), ELECTR NETWORK, 05 December 2020 - 08 December 2020, http://dx.doi.org/10.1182/blood-2020-138421
,2020, 'DDEL-12. NANOPARTICLE DELIVERY OF DOXORUBICIN FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii286 - iii286, http://dx.doi.org/10.1093/neuonc/noaa222.047
,2019, '[Cu-64]CuCl2 PET metallomics for determining the anticancer mechanism of novel drug Dextran-Catechin', in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, WILEY, Vol. 62, pp. S526 - S527, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000468965200440&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2019, 'Copper homeostasis: A new player in anti-tumor immune response', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, GA, Atlanta, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), GA, Atlanta, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.SABCS18-3224
,2019, 'Targeting AKT activity inhibits MYCN and sensitizes neuroblastoma to chemotherapeutic agents', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, GA, Atlanta, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), GA, Atlanta, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-3435
,2018, 'Harnessing copper in cancer to enhance anti-tumor immune response', in ANNALS OF ONCOLOGY, OXFORD UNIV PRESS, SWITZERLAND, Geneva, Vol. 29, pp. 35 - 35, presented at ESMO Immuno-Oncology Congress, SWITZERLAND, Geneva, 13 December 2018 - 16 December 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000459294800106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2018, 'PO-354 Star-shaped gene silencing nanoparticles– an advanced approach to treating medulloblastoma', in ESMO Open, Elsevier BV, Vol. 3, pp. A367 - A368, http://dx.doi.org/10.1136/esmoopen-2018-eacr25.866
,2017, 'Dextran-Catechin inhibits angiogenesis by disrupting copper homeostasis in endothelial cells', in Scientific Reports, Springer Nature, England, Vol. 7, pp. 7638, England, http://dx.doi.org/10.1038/s41598-017-07452-w
,2016, 'Imaging neuroblastoma xenograft using [Cu-64]CuCl2 for evaluation of novel treatment based on Dextran/Catechin conjugate', in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, SPRINGER, SPAIN, Barcelona, Vol. 43, pp. S480 - S480, presented at Annual Congress of the European-Association-of-Nuclear-Medicine, SPAIN, Barcelona, 15 October 2016 - 19 October 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000391802400670&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2015, 'beta III-Tubulin Regulates Sensitivity to Nab-Paclitaxel (Abraxane (R)) in Pancreatic Cancer', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 44, pp. 1414 - 1415, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000363324000260&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2015, 'beta IVb-Tubulin is a Novel Therapeutic Target for the Treatment of Pancreatic Cancer', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 44, pp. 1414 - 1414, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000363324000259&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2015, 'Erratum: Effective Delivery of siRNA into Cancer Cells and Tumors Using Well-Defined Biodegradable Cationic Star Polymers (Molecular Pharmaceutics (2013) 10: 6 (2435−2444) DOI: 10.1021/mp400049e)', in Molecular Pharmaceutics, Vol. 12, pp. 1004, http://dx.doi.org/10.1021/acs.molpharmaceut.5b00092
,2014, 'MICROTUBULE TARGETS IN CANCER: POTENTIAL OF NANOTECHNOLOGY-BASED THERAPEUTICS', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, Vol. 10, pp. 19 - 19, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344745100038&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2014, '217: The identification of novel targets in β-catenin-driven acute myeloid leukemic stem cells', in European Journal of Cancer, Elsevier, Vol. 50, pp. s50, http://dx.doi.org/10.1016/s0959-8049(14)50188-8
,2013, 'SILENCING THE TUBB3 GENE IN VIVO SENSITISES NON-SMALL CELL LUNG CANCER TO CISPLATIN', in JOURNAL OF THORACIC ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 8, pp. S773 - S773, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339624903299&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2013, 'beta III-tubulin in glioblastoma: An emerging multifactorial survival factor role in chemotherapy response and tumor formation.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, Vol. 73, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-3431
,2012, 'beta III-TUBULIN AND GLIOBLASTOMA: ROLE IN DRUG RESISTANCE AND TUMOURIGENESIS', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, Vol. 8, pp. 303 - 304, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310544400264&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2012, 'Repression of Essential Telomerase Components Mediates Anti-proliferative Effects in Isogenic Immortal and Tumorigenic Cells, but not Normal Cells', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, SPAIN, Barcelona, Vol. 48, pp. S79 - S80, presented at 22nd Biennial Congress of the European-Association-for-Cancer-Research, SPAIN, Barcelona, 07 July 2012 - 10 July 2012, http://dx.doi.org/10.1016/S0959-8049(12)71017-1
,2012, 'Stathmin suppression influences ROCK signaling and reduces cell invasion and metastasis in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-1444
,2011, 'Drug repositioning: Propanolol potentiates the anticancer efficacy of chemotherapeutic agents through modulation of angiogenesis', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 71, http://dx.doi.org/10.1158/1538-7445.AM2011-2555
,2011, 'Identifying the mechanisms of action and resistance to the novel multi-kinase inhibitor ENMD-2076 in leukemia', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 71, http://dx.doi.org/10.1158/1538-7445.AM2011-730
,2010, 'Beta III- and Beta IVB-Tubulin Mediate Sensitivity to Chemotherapeutic Drugs in Pancreatic Cancer Cells', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 39, pp. 1330 - 1330, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000282946600138&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2010, 'Beta III- and beta IVb-tubulin mediate sensitivity to chemotherapeutic drugs in pancreatic cancer cells', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL PUBLISHING, INC, Vol. 25, pp. A76 - A76, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000283321200206&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2009, 'Differential effects of \#946;III-tubulin on drug-induced microtubule dynamics and mitotic arrest', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 69, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209702604318&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2009, 'Novel role of \#946;III-tubulin in tumorigenesis and drug sensitivity in non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 69, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209701801261&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2006, 'Differential proteomic analysis of low-level anti-microtubule resistance in acute lymphoblastic leukaemia', in EJC SUPPLEMENTS, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 4, pp. 57 - 57, http://dx.doi.org/10.1016/S1359-6349(06)70187-2
,1985, 'MONITORING REPAIR AND REPLICATIVE-INDUCED STRUCTURAL-CHANGE IN CULTURES OF PROLIFERATING MAMMALIAN-CELLS', in MEDICAL AND PEDIATRIC ONCOLOGY, WILEY-LISS, Vol. 13, pp. 135 - 135, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1985AHS3500014&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,Patents
2016, Methods for detecting and modulating the sensitivity of tumour cells to anti-mitotic agents, China, Patent No.
,Preprints
2022, A 3D bioprintable hydrogel with tuneable stiffness for exploring cells encapsulated in matrices of differing stiffnesses, http://dx.doi.org/10.1101/2022.10.06.511222
,2022, βIII-Tubulin is a Brake on Extrinsic Cell-Death in Pancreatic Cancer, http://dx.doi.org/10.1101/2022.09.29.510034
,2021, A high-throughput 3D bioprinted cancer cell migration and invasion model with versatile and broad biological applicability, http://dx.doi.org/10.1101/2021.12.28.474387
,2021, Spatial-temporal analysis of nanoparticles in live tumor spheroids impacted by cell origin and density, http://dx.doi.org/10.1101/2021.10.26.465839
,A 3D Bioprinter Specifically Designed for the High-Throughput Production of Matrix-Embedded Multicellular Spheroids, http://dx.doi.org/10.2139/ssrn.3646560
,Other
2023, Data from Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion, http://dx.doi.org/10.1158/0008-5472.c.6512334.v1
,2023, Data from Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion, http://dx.doi.org/10.1158/0008-5472.c.6512334
,