Select Publications
Journal articles
2005, 'The retinoid anticancer signal: mechanisms of target gene regulation', British Journal of Cancer, 93, pp. 310 - 318, http://dx.doi.org/10.1038/sj.bjc.6602700
,2005, 'The role of the multidrug resistance-associated protein 1 gene in neuroblastoma biology and clinical outcome', Cancer Letters, 228, pp. 241 - 246
,2004, 'Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies', Blood, 103, pp. 3905 - 3914, http://dx.doi.org/10.1182/blood-2003-08-2911
,2004, 'Mechanisms of embryonal tumor initination: Distinct roles for MycN expression and MYCN amlification.', Proceedings of the National Academy of Sciences of the United States of America, 101, pp. 12664 - 12669
,2004, 'MYCN-mediated regulation of the MRP1 promoter in human neuroblastoma', Oncogene, 23, pp. 753 - 762
,2004, 'Neuronal-associated microtubule proteins class III B-tubulin and MAP2c in neuroblastoma: Role in resistance to microtubule-targeted drugs.', Molecular Cancer Therapeutics, 3, pp. 1137 - 1146
,2004, 'Regions syntenic to human 17q are gained in mouse and rat neuroblastoma.', Genes Chromosomes and Cancer, 40, pp. 158 - 163
,2003, 'Importance of minimal residual disease testing during the second year of disease: Still no answer? Reply', JOURNAL OF CLINICAL ONCOLOGY, 21, pp. 4464 - 4465, http://dx.doi.org/10.1200/JCO.2003.99.188
,2003, 'Cloning and characterisation of the human neural cell adhesion molecule, (CNTN4) ( alias BIG-2)', Cytogenetic and Genome Research, 101, pp. 1 - 17
,2003, 'Combined RAR and RXr-specific ligands overcome N-myc-associated retinoid resistance in neuroblastoma cells', Biochemical and Biophysical Research Communications, 302, pp. 462 - 468
,2003, 'Effects of MYCN antisense oligonucleotide administration on tumorigenesis in a murine model of neuroblastoma', Journal of National Cancer Institute, 95, pp. 1394 - 1403
,2003, 'Growth inhibitory retinoid effects after recruitment of retinoid X receptor B to the retinoic acid receptor B promoter', International Journal of Cancer, 105, pp. 856 - 867
,2003, 'Importance of minimal residual disease testing during teh second year of therapy for children with acute lymphoblastic leukemia', Journal of Clinical Oncology, 21, pp. 704 - 709
,2003, 'Microtubule alterations and mutations induced by desoxyepothilone B: Implications for drug-target', Chemistry and biology, 10, pp. 597 - 607
,2003, 'The p53 pathway and its inactivitation in neuroblastoma', Cancer Letters, 197, pp. 93 - 98
,2002, 'A simple method for the isolation of genomic DNA from mouse tail free of real-time PCR inhibitors', Journal of Biochemical and Biophysical Methods, 52, pp. 145 - 149
,2002, 'Genomic imbalances in drug-resistant T-cell acute lymphoblastic CEM leukemia cell lines', Blood Cells Molecules and Diseases, 29, pp. 1 - 13
,2002, 'Role of E45K reduced folate carrier gene mutation in methotrexate resistance in human leukaemia cells', Leukemia, 16, pp. 2379 - 2387
,2002, 'Testing of new agents in childhood cancer preclinical models(meeting summary)', Clinical Cancer Research, 8, pp. 3646 - 3657
,2002, 'The non-obese diabetic/severe combined immunodeficient (NOD/SCID) mouse model of Childhood acute lymphblastic leukemia reveals intrinsic differences in biological characteristics at diagnosis and relapse', Blood, 99, pp. 4100 - 4108
,2001, 'Genomic and allelic expression status of the p73 gene in human neuroblastoma', Medical and Pediatric Oncology, 36, pp. 45 - 47, http://dx.doi.org/10.1002/1096-911X(20010101)36:1<45::AID-MPO1012>3.0.CO;2-E
,2001, 'Relationship between histopathological features, MYCN amplification, and prognosis: A UKCCSG study', Medical and Pediatric Oncology, 36, pp. 169 - 176, http://dx.doi.org/10.1002/1096-911X(20010101)36:1<169::AID-MPO1041>3.0.CO;2-U
,2001, 'Expression of the putative tumour suppressor gene, p73, in neuroblastoma and other childhood tumours', Medical and Pediatric Oncology, 36, pp. 48 - 51, http://dx.doi.org/10.1002/1096-911X(20010101)36:1<48::AID-MPO1013>3.0.CO;2-8
,2001, 'Reversal of multidrug resistance-associated protein-mediated drug resistance in cultured human neuroblastoma cells by the quinolone antibiotic difloxacin', MEDICAL AND PEDIATRIC ONCOLOGY, 36, pp. 177 - 180, http://dx.doi.org/10.1002/1096-911X(20010101)36:1<177::AID-MPO1042>3.0.CO;2-Q
,2001, 'Detection of minimal residual disease in peripheral blood prior to clonical relapse of childhood acute lympohoblastic leukaemia using PCR', Molecular and Cellular Probes, 15, pp. 99 - 103
,2001, 'Expression of GAGE genes in neuroblastoma by reverse transcription - polymerase chain reaction', Cancer Research Therapy and Control, 11, pp. 197 - 203
,2001, 'Expression of the Putative Tumour Suppressor Gene, p73, in Neuroblastome and Other Childhood Tumours', Medical Pediatric Oncology, pp. 48 - 51
,2001, 'High Level resistance to Glucocorticoids, assosiated with a dysfunctional glucocorticoid receptor, in childhood acute lymphoblastic leukemia cells selected for methotrexate resistance', Leukemia, 15, pp. 929 - 935
,2001, 'MRP1 gene expression level regulates the death and differentation response of neuroblastoma cells', British Journal of Cancer, 85, pp. 1564 - 1571, http://dx.doi.org/10.1054/bjoc.2001.2144
,2001, 'Multiple microtubule alterations are associated with vinca alkaloid resistance in human leukemia cells', Cancer research, pp. 5803 - 5809
,2001, 'Reversal of MRP-mediated drug resistance in cultured human neuroblastome cells by the quinlone antibiotic, difloxacin', Medical Pediatric Oncology, pp. 177 - 180
,2001, 'Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G.A variant at position 80 and transport properties of the his27 And Arg27 carriers', Clinical Cancer Research, 7, pp. 3416 - 3422, https://aacrjournals.org/clincancerres/article/7/11/3416/288667/Single-Nucleotide-Polymorphisms-in-the-Human
,2000, 'Expression of N-myc and MRP genes and their relationship to N-myc gene dosage and tumor formation in murine neuroblastoma model', Medical and Pediatric Oncology, pp. 585 - 589
,2000, 'MYCN expression is not prognostic of adverse outcomes in advanced-stage neuroblastoma with non-amplified MYCN', Journal of Clinical Oncology, 18, pp. 3604 - 3613
,2000, 'Simultaneous detection and quantification of minimal residual disease in childhood acute lymphoblastic leukaemia using real-time polymerase chain reaction', British Journal of Haematology, 109, pp. 430 - 434
,2000, 'Synergy between 5` and 3` flanking regions of the human tyrosine hydroxylase gene ensures specific, high-level expression in neuroblastoma cells', Neuroscience Letters, pp. 147 - 150
,1999, 'The effect of late intensification of therapy in children with acute lymphoblastic leukaemia and minimal residual disease.', BLOOD, 94, pp. 658A - 658A, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000083790302970&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,1999, 'Altered expression of the MYCN Oncogene modulates MRP gene expression and response to cytotoxic drugs in neuroblastoma cells', Oncogene, 18, pp. 2777 - 2782
,1999, 'Use of tumor-specific gene expression for the differential diagnosis of neuroblastoma from other pediatric small-round-cell malignancies', American Journal of Pathology, 155, pp. 17 - 21
,1998, 'Absence of MEN2A- or 2B- type RET mutations in primary neuroblastoma tumour tissue', Molecular and Cellular Probes, pp. 239 - 242
,1998, 'Favorable prognostic signifiance of high-level retinoic acid receptor B expression in neuroblastoma mediated by effects on cell cycle regulation', Oncogene, pp. 751 - 759
,1998, 'In Vitro effects of MYCN sense and antisense expression in MYCN-amplified human neuroblastoma cells', Anticancer Research, pp. 1793 - 1798
,1998, 'Molecular detection of acute Lymphoblastic Leukaemia in boys with testicular relapse', Molecular Pathology, pp. 277 - 281
,1998, 'P-glycoprotein-mediated methotrexate resistance in CCRF-CEM sublines deficient in Methotrexate accumulation due to a point mutation in the reduced folate carrier gene', International Journal of Cancer, pp. 176 - 181
,1998, 'Prognostic significance of MYCN oncgene expression in childhood neuroblastoma', Journal of Clinical Oncology, pp. 3286 - 3294
,1997, 'Low specificity of PGP9.5 expression for detection of micrometastatic neuroblastoma', British Journal of Cancer, 75, pp. 1779 - 1781, http://dx.doi.org/10.1038/bjc.1997.303
,1997, 'EVIDENCE THAT THE N-MYC ONCOGENE REGULATES MRP GENE EXPRESSION IN NEUROBLASTOMA', European Journal of Cancer, pp. 1911 - 1916
,1997, 'Expression of multiple endocrine neoplasia 2B ret in neuroblastoma cells alters cell adhesion in vitro, enhances metastatic behaviour in vivo, and activates jun kinase 1', Cancer research, pp. 5399 - 5405
,1997, 'IMPROVED PCR ASSAY FOR THE DETECTION OF ANTIGEN RECEPTOR GENE REARRANGEMENTS', Journal of Biochemical and Biophysical Methods, pp. 3 - 10
,1997, 'SENSITIVE NON- RADIOACTIVE PCR DETECTION OF CLONAL T-CELL RECEPTOR GAMMA GENE REARRANGEMENTS IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKAEMIA', British Journal of Haematology, pp. 995 - 998
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