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Preprints

Mayoh C; Gifford AJ; Terry R; Lau LM; Wong M; Rao P; Shai-Hee T; Saletta F; Khuong-Quang D-A; Qin V; Mateos M; Meyran D; Miller KE; Yuksel A; Mould EV; Bowen-James R; Govender D; Senapati A; Zhukova N; Omer N; Dholaria H; Alvaro F; Tapp H; Diamond Y; Pozza LD; Moore AS; Nicholls W; Gottardo NG; McCowage G; Hansford JR; Khaw S-L; Wood PJ; Catchpoole D; Cottrell CE; Mardis ER; Marshall GM; Tyrrell V; Haber M; Ziegler DS; Vittorio O; Trapani JA; Cowley MJ; Neeson PJ; Ekert PG, A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer, http://dx.doi.org/10.1101/2022.09.16.508179

Mayoh C; Barahona P; Lin A; Cui L; Ajuyah P; Altekoester A; Lau LM; Khuong-Quang D-A; Sullivan P; Senapati A; Nagabushan S; Sullivan A; Omer N; Moore AS; Nicholls W; Endersby R; Gottardo NG; McCowage G; Pozza LD; Hansford JR; Khaw S-L; Wood PJ; Trahair TN; Marshall GM; Ziegler DS; Tyrrell V; Haber M; Wong M; Ekert PG; Cowley MJ, Expanding the utility of transcriptome analysis for mutation detection in high-risk childhood precision oncology, http://dx.doi.org/10.1101/2025.06.25.661445

Rokita JL; Rathi KS; Cardenas MF; Upton KA; Jayaseelan J; Cross KL; Pfeil J; Ritenour LE; Modi A; Farrel A; Way GP; Kendsersky NM; Patel K; Lopez G; Vaksman Z; Mayoh C; Nance J; McCoy K; Haber M; Evans K; McCalmont H; Bendak K; Böhm JW; Marshall GM; Tyrrell V; Kalletla K; Braun FK; Qi L; Du Y; Zhang H; Lindsay HB; Zhao S; Shu J; Baxter P; Morton C; Kurmashev D; Zheng S; Chen Y; Bowen J; Bryan AC; Leraas KM; Coppens SE; Doddapaneni H; Momin Z; Zhang W; Sacks GI; Hart LS; Krytska K; Mosse YP; Gatto GJ; Sanchez Y; Greene CS; Diskin SJ; Vaske OM; Haussler D; Gastier-Foster JM; Kolb EA; Gorlick R; Li X-N; Reynolds CP; Kurmasheva RT; Houghton PJ; Smith MA; Lock RB; Raman P; Wheeler DA; Maris JM, Genomic profiling of childhood tumor patient-derived xenograft models to enable rational clinical trial design, http://dx.doi.org/10.1101/566455

Sullivan AJ; Khuong-Quang D-A; Villani A; Wong-Erasmus M; Trinder S; Lau LMS; Barahona P; Altekoester A-K; Rumford M; Dias K; Mayoh C; Fuentes-Bolanos NA; Courtney EK; El-Kamand S; Cui L; Lin A; Davidson S; Yuki KE; Sanders N; Staunton J; Jessop S; Sriharan S; Alvaro F; Anazodo A; Bhatia K; Campbell M; Foresto S; Gottardo NG; Kirby M; Khaw SL; Manoharan N; McCowage G; Moore AS; Nicholls W; O’Connor M; Padhye B; Ryan AL; Super L; Wood PJ; Davies J; D’Arcy C; Gifford AJ; Rodriguez M; Tucker KM; Pinese M; Ekert PG; Haber M; Tyrrell V; Trahair TN; Marshall GM; Shlien A; Cowley MJ; Ziegler DS, High clinical utility of comprehensive multi-omic molecular profiling of rare and hard-to-diagnose pediatric tumors, http://dx.doi.org/10.21203/rs.3.rs-10108527/v1

Sullivan AJ; Khuong-Quang D-A; Villani A; Wong-Erasmus M; Trinder S; Lau LMS; Barahona P; Altekoester A-K; Rumford M; Dias K; Mayoh C; Fuentes-Bolanos NA; Courtney EK; El-Kamand S; Cui L; Lin A; Davidson S; Yuki KE; Sanders N; Staunton J; Jessop S; Sriharan S; Alvaro F; Anazodo A; Bhatia K; Campbell M; Foresto S; Gottardo NG; Kirby M; Khaw SL; Manoharan N; McCowage G; Moore AS; Nicholls W; O’Connor M; Padhye B; Ryan AL; Super L; Wood PJ; Davies J; D’Arcy C; Gifford AJ; Rodriguez M; Tucker KM; Pinese M; Ekert PG; Haber M; Tyrrell V; Trahair TN; Marshall GM; Shlien A; Cowley MJ; Ziegler DS, High clinical utility of comprehensive multi-omic molecular profiling of rare and hard-to-diagnose pediatric tumors, http://dx.doi.org/10.64898/2026.07.25.26358936

Han JZR; Phimmachanh M; Hastings JF; Leong H; Ng BH; Ni J; Fontaine-Titley A; Cadell AL; O’Donnell YE; Clearwater M; Kamili A; Haber M; Norris M; Timpson P; Trahair TN; Fletcher JI; Fey D; Kolch W; Latham SL; Croucher DR, Inclusion of JNK-independent drugs within multi-agent chemotherapy improves response in relapsed high-risk neuroblastoma, http://dx.doi.org/10.1101/2025.04.26.650760

Fuentes-Bolanos NA; Courtney E; Mayoh C; Warby M; Lau LMS; Wong-Erasmus M; Khuong-Quang D-A; Barahona P; Padhye B; El-Kamand S; Nunag S; Ajuyah P; Sherstyuk A; Altekoester A-K; Sullivan A; Poplawski N; Kiraly-Borri C; O’Sullivan S; Marfan H; Alli R; Curnow L; Bhatia K; Anazodo A; Trahair TN; Mateos M; Hansford JR; Dholaria H; Josephi-Taylor S; Moore AS; Nicholls W; Gottardo NG; Downie P; Khaw S-L; Tapp H; McCowage G; Dalla-Pozza L; Alvaro F; Wood PJ; Tyrrell V; Haber M; Cowley MJ; Ekert PG; Marshall GM; Kirk J; Tucker K; Pinese M; Ziegler DS, Integrated germline and somatic molecular profiling to detect cancer predisposition has a high clinical impact in poor-prognosis paediatric cancer, http://dx.doi.org/10.1101/2024.08.08.24311493

Ziegler D; Lau L; Khuong-Quang D-A; Mayoh C; Wong M; Barahona P; Ajuyah P; Senapati A; Nagabushan S; Sherstyuk A; Altekoester A-K; Fuentes-Bolanos N; Yeung V; Sullivan A; Diamond Y; Omer N; Jessop S; Battaglia L; Zhukova N; Cui L; Lin A; Gifford A; Fleuren E; Dalla-Pozza L; Moore A; Khaw S; Eisenstat D; Gottardo N; Wood P; Tapp H; Alvaro F; McCowage G; Nicholls W; Hansford J; Manoharan N; Kotecha R; Mateos M; Lock R; Tyrrell V; Haber M; Trahair T; Cowley M; Ekert P; Marshall G, Precision-guided treatment improves outcomes for children with high-risk cancers, http://dx.doi.org/10.21203/rs.3.rs-3376668/v1

Kamili A; Hearn BA; Temelkoska I; Solomon J; Wheatley MS; Bui CHT; Atkinson CJ; Elhassadi L-J; Qureshi S; Murray J; Cadiz R; Gifford AJ; Cui L; Crowley L; Lin A; Mayoh C; Wong-Erasmus M; Failes TW; Arndt GM; Haber M; Norris MD; Dolman MEM; Trahair TN; Fletcher JI, Preclinical trial supports dual inhibition of BCL2 and Aurora kinase A for MYCN -amplified high-risk neuroblastoma, http://dx.doi.org/10.64898/2026.09.06.749004

Hu W; Kumar A; Qi S; Sadras T; Casan J; Ma D; Brown L; Haber M; Voskoboinik I; Trapani J; Ekert P; Fareh M, Single-base precision design of CRISPR-Cas13b enables systematic silencing of oncogenic fusions, http://dx.doi.org/10.21203/rs.3.rs-1714034/v1

Hu W; Kumar A; Qi S; Sadras T; Casan JM; Ma D; Brown LM; Haber M; Voskoboinik I; Trapani JA; Ekert PG; Fareh M, Single-base precision design of CRISPR-Cas13b enables systematic silencing of oncogenic fusions, http://dx.doi.org/10.1101/2022.06.22.497105

Mayoh C; Li W; Toumari M; Bazaz SR; Gerard A-L; Lowe A; Barahona P; Lau LM; Staunton J; Jacobson E; Nagabushan S; Manoharan N; Mitchell R; Ong F; Wong-Erasmus M; Ekert PG; Tyrrell V; Haber M; Ziegler DS; Cowley MJ; Mateos MK; Salomon R, Single-cell RNA-sequencing of cerebral spinal fluid identifies circulating tumour cells in children with brain cancer, http://dx.doi.org/10.64898/2025.12.18.694991

Nelson CB; Rogers S; Roychoudhury K; Tan YS; Atkinson CJ; Sobinoff AP; Tomlinson CG; Hsu A; Lu R; Dray E; Haber M; Fletcher JI; Cesare AJ; Hegde RS; Pickett HA, The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation, http://dx.doi.org/10.1101/2022.10.10.511510

Maris J; Soria-Bretones I; Casás-Selves M; Samanta M; Groff D; Murray J; Fletcher J; Farrel A; Pastor S; Patel K; Goodfellow EG; Li L; Caron C; Shiwram A; Kim H; Henry D; Laterreur N; Bowlan J; Krytska K; Neuhauser S; Stearns T; Schubert J; Wu J; Surrey L; Álvarez-Quilón A; Vallée F; Nejad P; Schonhoft J; Li J; Veloso A; Young J; Hyer M; Morris S; Mossé YP; Marshall G; Haber M; Zimmermann M, The PLK4 inhibitor RP-1664 demonstrates potent single-agent efficacy in neuroblastoma models through a dual mechanism of sensitivity, http://dx.doi.org/10.21203/rs.3.rs-7014295/v1

Azfar M; Gao W; Van den Haute C; Xiao L; Karsa M; Pandher R; Ronca E; Bongers A; Karsa A; Spurling D; Guo X; Mayoh C; Burns MR; Verhelst SHL; Norris MD; Haber M; Vangheluwe P; Somers K, The polyamine transporter ATP13A3 mediates DFMO-induced polyamine uptake in neuroblastoma, http://dx.doi.org/10.1101/2024.02.20.581161


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