By Professor Shane T. Grey

Journal articles

Sivanathan KN; Rojas-Canales DM; Hope CM; Krishnan R; Carroll RP; Gronthos S; Grey ST; Coates PT, 2015, 'Interleukin-17A-Induced Human Mesenchymal Stem Cells Are Superior Modulators of Immunological Function', Stem Cells, 33, pp. 2850 - 2863, http://dx.doi.org/10.1002/stem.2075

Malle EK; Zammit NW; Walters SN; Koay YC; Wu J; Tan BM; Villanueva JE; Brink R; Loudovaris T; Cantley J; McAlpine SR; Hesselson D; Grey ST, 2015, 'Nuclear factor κB-inducing kinase activation as a mechanism of pancreatic β cell failure in obesity', Journal of Experimental Medicine, 212, pp. 1239 - 1254, http://dx.doi.org/10.1084/jem.20150218

Villanueva JE; Malle EK; Gardam S; Silveira PA; Zammit NW; Walters SN; Brink R; Grey ST, 2015, 'TRAF2 regulates peripheral CD8⁺ T-cell and NKT-cell homeostasis by modulating sensitivity to IL-15', European Journal of Immunology, 45, pp. 1820 - 1831, http://dx.doi.org/10.1002/eji.201445416

Roden DL; Grey ST, 2015, 'Telling the tiger by its stripes: Mapping the genomics of kidney graft tolerance in real time', Kidney International, 87, pp. 875 - 877, http://dx.doi.org/10.1038/ki.2015.66

Villanueva JE; Malle EK; Gardam S; Silveira PA; Zammit NW; Walters SN; Brink R; Grey ST, 2015, 'TRAF2 regulates peripheral CD8⁺ T-cell and NKT-cell homeostasis by modulating sensitivity to IL-15', European Journal of Immunology, http://dx.doi.org/10.1002/eji.201445416

Zammit NW; Malle EK; Walters SN; Goodnow CC; Grey ST, 2014, 'Functional genomics identifies tnfaip3/A20 as a diabetes protective gene', DIABETOLOGIA, 57, pp. S103 - S103, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344386100229&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Malle EK; Tan BM; Walters SN; Zammit NW; Brink R; Cantley J; Grey ST, 2014, 'The non-canonical NF kappa B pathway as a novel player in beta cell dysfunction in diabetes', DIABETOLOGIA, 57, pp. S48 - S48, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344386100098&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Scott C; Bonner J; Min D; Boughton P; Stokes R; Cha KM; Walters SN; Maslowski K; Sierro F; Grey ST; Twigg S; McLennan S; Gunton JE, 2014, 'Reduction of ARNT in myeloid cells causes immune suppression and delayed wound healing', American Journal of Physiology - Cell Physiology, 307, http://dx.doi.org/10.1152/ajpcell.00306.2013

Walters SN; Webster KE; Daley S; Grey ST, 2014, 'A role for intrathymic B cells in the generation of natural regulatory T cells', Journal of Immunology, 193, pp. 170 - 176, http://dx.doi.org/10.4049/jimmunol.1302519

Mariño E; Walters SN; Villanueva JE; Richards JL; Mackay CR; Grey ST, 2014, 'BAFF regulates activation of self-reactive T cells through B-cell dependent mechanisms and mediates protection in NOD mice', European Journal of Immunology, 44, pp. 983 - 993, http://dx.doi.org/10.1002/eji.201344186

Zammit NW; Grey ST, 2014, 'Emerging roles for a20 in islet biology and pathology', , 809, pp. 141 - 162, http://dx.doi.org/10.1007/978-1-4939-0398-6_9

Hughes A; Rojas-Canales D; Drogemuller C; Voelcker NH; Grey ST; Coates PTH, 2014, 'IGF2: An endocrine hormone to improve islet transplant survival', Journal of Endocrinology, 221, http://dx.doi.org/10.1530/JOE-13-0557

Zammit NW; Tan BM; Walters SN; Liuwantara D; Villanueva JE; Malle EK; Grey ST, 2013, 'Low-dose rapamycin unmasks the protective potential of targeting intragraft NF-κB for islet transplants', Cell Transplantation, 22, pp. 2355 - 2366, http://dx.doi.org/10.3727/096368912X658737

Stokes RA; Cheng K; Deters N; Lau SM; Hawthorne WJ; O'Connell PJ; Stolp J; Grey S; Loudovaris T; Kay TW; Thomas HE; Gonzalez FJ; Gunton JE, 2013, 'Hypoxia-inducible factor-1α (HIF-1α) potentiates β-cell survival after islet transplantation of human and mouse islets.', Cell transplantation, 22, pp. 253 - 266

Mladenova D; Pangon L; Currey N; Ng I; Musgrove EA; Grey ST; Kohonen-Corish MR, 2013, 'Sulindac activates NF-κB signaling in colon cancer cells', Cell Communication and Signaling, 11, http://dx.doi.org/10.1186/1478-811X-11-73

Walters SN; Luzuriaga J; Chan JY; Grey ST; Laybutt DR, 2013, 'Influence of chronic hyperglycemia on the loss of the unfolded protein response in transplanted islets', Journal of Molecular Endocrinology, 51, pp. 225 - 232, http://dx.doi.org/10.1530/JME-13-0016

Grey ST, 2013, 'B-lymphocyte therapy for Type 2 diabetes: The 'B' side of diabetic medication?', Immunotherapy, 5, pp. 669 - 672, http://dx.doi.org/10.2217/imt.13.52

Stolp J; Mariño E; Batten M; Sierro F; Cox SL; Grey ST; Silveira PA, 2013, 'Intrinsic molecular factors cause aberrant expansion of the splenic marginal zone B cell population in nonobese diabetic mice', Journal of Immunology, 191, pp. 97 - 109, http://dx.doi.org/10.4049/jimmunol.1203252

Mariño E; Tan B; Binge L; Mackay CR; Grey ST, 2013, 'Erratum: B-Cell cross-presentation of autologous antigen precipitates diabetes (Diabetes( 2012) 61 (2893-2905))', Diabetes, 62, pp. 662, http://dx.doi.org/10.2337/db13-er02

Cantley J; Walters SN; Jung MH; Weinberg A; Cowley MJ; Whitworth TP; Kaplan W; Hawthorne WJ; O'Connell PJ; Weir G; Grey ST, 2013, 'A preexistent hypoxic gene signature predicts impaired islet graft function and glucose homeostasis', Cell Transplantation, 22, pp. 2147 - 2159, http://dx.doi.org/10.3727/096368912X658728

Walters SN; James C; Jung M-H; Weinberg A; Cowley MJ; Kaplan W; Hawthorne WJ; O'Connell PJ; Weir G; Grey ST, 2012, 'A Pre-Existent Hypoxic Gene Signature Predicts Impaired Islet Graft Function and Glucose Homeostasis', TRANSPLANTATION, 94, pp. 710 - 710, http://dx.doi.org/10.1097/00007890-201211271-01394

Walters SN; Webster KE; Daley S; Grey ST, 2012, 'B Cell-Dependent Control of Allograft Tolerance through Expansion of Thymic CD4+Foxp3+T Cells', TRANSPLANTATION, 94, pp. 256 - 256, http://dx.doi.org/10.1097/00007890-201211271-00474

Cowley M; Walters S; Zammit N; Hawthorne W; Gunton J; Chapman J; Oconnell P; Grey ST, 2012, 'Human Islets Express a Marked Pro-Inflammatory Molecular Signature Prior to Transplantation', TRANSPLANTATION, 94, pp. 162 - 162, http://dx.doi.org/10.1097/00007890-201211271-00300

Zammit NW; Walters SN; Tan B; Villanueava J; Grey ST, 2012, 'Improved Survival Characteristics of An Inflammatory Suppressed Allograft', TRANSPLANTATION, 94, pp. 465 - 465, http://dx.doi.org/10.1097/00007890-201211271-00886

Zammit NW; Walters SN; Tan B; Villanueava J; Grey ST, 2012, 'Improved Survival Characteristics of An Inflammatory Suppressed Allograft', TRANSPLANTATION, 94, pp. 306 - 306, http://dx.doi.org/10.1097/00007890-201211271-00568

Saito M; Zhang GY; Wang YM; Hu M; Walters S; Zhou J; Sawyer A; Chapman J; Grey ST; Alexander S, 2012, 'Prolonged Cardiac Allograft Survival in BAFF-Transgenic Mice Associated with Increased Tregs', TRANSPLANTATION, 94, pp. 441 - 441, http://dx.doi.org/10.1097/00007890-201211271-00834

Villanueva J; Walters SN; Marino E; Brink R; Grey ST, 2012, 'TRAF2 Governs the T Cell Alloimmune Response', TRANSPLANTATION, 94, pp. 14 - 14, http://dx.doi.org/10.1097/00007890-201211271-00025

Marino E; Grey S, 2012, 'B cells as effectors and regulators of autoimmunity', Autoimmunity, 45, pp. 377 - 387, http://dx.doi.org/10.3109/08916934.2012.665527

Marino E; Tan B; Binge LC; Mackay CR; Grey ST, 2012, 'B-cell cross-presentation of autologous antigen precipitates diabetes', Diabetes, 61, pp. 2893 - 2905, http://dx.doi.org/10.2337/db12-0006

Campbell P; Weinberg A; Chee J; Mariana L; Ayala R; Hawthorne WJ; O''Connell PJ; Loudovaris T; Cowley MJ; Kay T; Grey S; Thomas H, 2012, 'Expression of pro- and antiapoptotic molecules of the Bcl-2 family in human islets postisolation', Cell Transplantation, 21, pp. 49 - 60, http://dx.doi.org/10.3727/096368911X566262

Cowley MJ; Weinberg A; Zammit NW; Walters SN; Hawthorne WJ; Loudovaris T; Thomas H; Kay T; Gunton J; Alexander SI; Kaplan W; Chapman J; O'Connell PJ; Grey ST, 2012, 'Human islets express a marked proinflammatory molecular signature prior to transplantation', Cell Transplantation, 21, pp. 2063 - 2078, http://dx.doi.org/10.3727/096368911X627372

Polhill TS; Zhang G; Hu M; Sawyer A; Zhou J; Saito M; Webster KE; Wang Y; Wang Y; Grey ST; Sprent J; Harris DJ; Alexander SP; Wang Y, 2012, 'IL-2/IL-2Ab complexes induce regulatory T cell expansion and protect against proteinuric CKD', Journal of the American Society of Nephrology, 23, pp. 1303 - 1308, http://dx.doi.org/10.1681/ASN.2011111130

Macia L; Yulyaningsih E; Pangon L; Nguyen AD; Lin S; Shi Y; Zhang L; Bijker MS; Grey ST; Mackay F; Herzog H; Sainsbury-Salis A, 2012, 'Neuropeptide y1 receptor in immune cells regulates inflammation and insulin resistance associated with diet-induced obesity', Diabetes, 61, pp. 3228 - 3238, http://dx.doi.org/10.2337/db12-0156

Forbes JM; Söderlund J; Yap FYT; Knip M; Andrikopoulos S; Ilonen J; Simell O; Veijola R; Sourris KC; Coughlan MT; Forsblom C; Slattery R; Grey ST; Wessman M; Yamamoto H; Bierhaus A; Cooper ME; Groop PH, 2011, 'Erratum to: Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes (Diabetologia DOI: 10.1007/s00125-011-2058-z)', Diabetologia, 54, pp. 1586 - 1587, http://dx.doi.org/10.1007/s00125-011-2145-1

Marino E; Silveira PA; Stolp J; Grey S, 2011, 'B cell-directed therapies in type 1 diabetes', Trends in Immunology, 32, pp. 287 - 294, http://dx.doi.org/10.1016/j.it.2011.03.006

McGuire HM; Walters SN; Vogelzang A; Lee CM; Webster KE; Sprent J; Christ DU; Grey S; King C, 2011, 'Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models', Diabetes, 60, pp. 867 - 875, http://dx.doi.org/10.2337/db10-1157

Forbes JM; Soderlund ; Yap F; Knip M; Andrikopoulos S; Ilonen J; Simell O; Veijola R; Sourris K; Coughlan C; Forsblom C; Slattery J; Grey S; Wessman M; Yamamoto H; Bierhaus M; Cooper M; Groop M, 2011, 'Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes', Diabetologia, 54, pp. 1032 - 1042, http://dx.doi.org/10.1007/s00125-011-2058-z

Zmuda EJ; Viapiano M; Grey S; Hadley G; Garcia-ocana A, 2010, 'Deficiency of Atf3, an adaptive-response gene, protects islets and ameliorates inflammation in a syngeneic mouse transplantation model', Diabetologia, 53, pp. 1438 - 1450, http://dx.doi.org/10.1007/s00125-010-1696-x

Grey S; Cowley M; Cantley J; Weinberg A; Hawthorne W; Alexander S; Gunton J; Loudovaris T; Williams L; Patel A; Walters SN; Kaplan W; OʼConnell PJ, 2010, 'HUMAN ISLETS PREPARED FOR CLINICAL TRANSPLANTATION EXHIBIT AN ALTERED GLYCOLYTIC PROFILE', Transplantation Journal, 90, pp. 373 - 373, http://dx.doi.org/10.1097/00007890-201007272-00689

Cantley J; Grey S; Maxwell P; Withers D, 2010, 'The hypoxia response pathway and beta-cell function', Diabetes Obesity and Metabolism, 12, pp. 159 - 167, http://dx.doi.org/10.1111/j.1463-1326.2010.01276.x

Marino E; Villanueva J; Walters SN; Liuwantara D; Mackay F; Grey S, 2009, 'CD4+CD25+ T-cells control autoimmunity in the absence of B-cells', Diabetes, 58, pp. 1568 - 1577

Webster K; Walters S; Kohler R; Mrkvan T; Boyman O; Surh C; Grey S; Sprent J, 2009, 'In vivo expansion of t reg cells with il-2-mab complexes: induction of resistance to eae and long-term acceptance of islet allografts without immunosuppression', Journal of Experimental Medicine, 206, pp. 751 - 760

Walters SN; Webster K; Sutherland AP; Gardam S; Groom JR; Liuwantara D; Marino E; Thaxton J; Weinberg A; Mackay F; Brink R; Sprent J; Grey S, 2009, 'Increased CD4+Foxp3+ T cells in BAFF-transgenic mice suppress T cell effector responses', Journal of Immunology, 182, pp. 793 - 801, http://www.ncbi.nlm.nih.gov/pubmed/19124722

Webster K; Walters S; Mrkvan T; Boyman O; Grey S; Sprent J, 2008, 'ALLOGRAFT TOLERANCE AFTER IN VIVO EXPANSION OF TREGS WITH IL-2/IL-2 MAB COMPLEXES', Transplantation, 86, pp. 8 - 8, http://dx.doi.org/10.1097/01.tp.0000332700.58733.14

Grey ST; Weinberg A; Cowley MJ; Walters SN; Hawthorne WJ; Patel A; Jimenez-Vera E; Williams L; Tabor B; Kaplan W; O'Connell PJ, 2008, 'GENE EXPRESSION PROFILING OF HUMAN ISLETS TO DETERMINE PREDICTORS OF CLINICAL ISLET TRANSPLANT OUTCOMES', Transplantation, 86, pp. 291 - 292, http://dx.doi.org/10.1097/01.tp.0000331928.59075.f3

Walters S; Webster K; Sutherland A; Groom J; Liuwantara D; Marino E; Mackay F; Sprent J; Grey S, 2008, 'GENERATING ALLOGRAFT TOLERANCE BY BAFF- DEPENDANT EXPANSION OF REGULATORY T CELLS', Transplantation, 86, pp. 257 - 257, http://dx.doi.org/10.1097/01.tp.0000332034.09691.5d

Liuwantara D; Gunton J; Yam A; Walters S; Marino E; McShea A; Grey S, 2008, 'GENERATING ISLET ALLOGRAFT TOLERANCE BY BLOCKING NF-KB ACTIVATION AND PREVENTING APOPTOSIS.', Transplantation, 86, pp. 18 - 18, http://dx.doi.org/10.1097/01.tp.0000332732.20615.8f

Stokes R; Cheng K; Scott C; Yim S; Grey S; Gonzalez F; Hawthorne W; O'Connell P; Gunton J, 2008, 'HYPOXIA INDUCIBLE FACTOR 1ALPHA (HIF-1ALPHA) IS REQUIRED FOR SUCCESSFUL ISLET TRANSPLANTATION AND INCREASING HIF-1ALPHA WITH DESFERRIOXAMINE MARKEDLY IMPROVES OUTCOMES', Transplantation, 86, pp. 141 - 142, http://dx.doi.org/10.1097/01.tp.0000332370.98129.43

Marino E; Batten ML; Groom JR; Walters SN; Liuwantara D; Mackay F; Grey S, 2008, 'Marginal-zone B-Cells of Nonobese diabetic mice expand with diabetes onset, invade the pancreatic lymph nodes, and present autoantigen to diabetogenic T-Cells', Diabetes, 57, pp. 395 - 404, http://dx.doi.org/10.2337/db07-0589

Grey S, 2008, 'Regulating inflammation - The ying and yang of NF-kappa B activation', Immunology and Cell Biology, 86, pp. 299 - 300, http://dx.doi.org/10.1038/icb.2008.21

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