By Professor Shane T. Grey

Journal articles

Groom JR; Fletcher C; Walters SN; Grey S; Watt S; Sweet M; Smyth MJ; MacKay CR; Mackay F, 2007, 'BAFF and MyD88 signals promote a lupuslike disease independent of T cells', Journal of Experimental Medicine, 204, pp. 1959 - 1971

Silveira PA; Serreze D; Grey S, 2007, 'Invasion of the killer B`s in type 1 diabetes', Frontiers in Bioscience, 12, pp. 2183 - 2193

Viardot AC; Grey S; Mackay F; Chisholm DJ, 2007, 'Potential antiinflammatory role of insulin via the preferential polarization of effector T cells toward a T helper 2 phenotype', Endocrinology, 148, pp. 346 - 353

Patel VI; Daniel S; Longo CR; Shrikhande GV; Scali ST; Czismadia E; Groft CM; Shukri T; Motley-Dore C; Ramsey HE; Fisher MD; Grey ST; Arvelo MB; Ferran C, 2006, 'A20, a modulator of smooth muscle cell proliferation and apoptosis, prevents and induces regression of neointimal hyperplasia', FASEB Journal, 20, pp. 1418 - 1430, http://dx.doi.org/10.1096/fj.05-4981com

Silveira PA; Grey S, 2006, 'B cells in the spotlight: innocent bystanders or major players in the pathogenesis of type 1 diabetes', Trends in Endocrinology and Metabolism, 17, pp. 128 - 135

Walters SN; Sutherland A; Thaxton J; Liuwantara D; Marino E; Mackay F; Grey S, 2006, 'BAFF alters T-cell-dependent immune responses allowing allograft acceptance', Immunology and Cell Biology, 84, pp. A3 - A3

Liuwantara D; Elliot M; Smith MA; Yam A; Walters SN; Marino E; McShea A; Grey S, 2006, 'Nuclear Factor-KB regulates beta-cell death - A critical role for A20 in beta-cell protection', Diabetes, 55, pp. 2491 - 2501

Jeffrey KL; Brummer T; Rolph MS; Liu SM; Callejas N; Grumont R; Gillieron C; Mackay F; Grey S; Camps M; Rommel C; Gerondakis S; MacKay CR, 2006, 'Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1', Nature Immunology, 7, pp. 274 - 283

Liuwantara D; Grey S, 2006, 'Signalling pathways determine allograft fate', Immunology and Cell Biology, 84, pp. A9 - A9

Walters SN; Liuwantara D; Marino E; Grey S, 2006, 'T-cell subsets required for islet allograft rejection', Immunology and Cell Biology, 84, pp. A16 - A16

Kunter U; Daniel S; Arvelo MB; Choi J; Shukri T; Patel VI; Longo CR; Scali ST; Shrikhande G; Rocha E; Czismadia E; Mottley C; Grey ST; Floege J; Ferran C, 2005, 'Combined expression of A1 and A20 achieves optimal protection of renal proximal tubular epithelial cells', Kidney International, 68, pp. 1520 - 1532, http://dx.doi.org/10.1111/j.1523-1755.2005.00564.x

Sisavanh M; Liu SM; Grey ST; Rolph MS, 2005, 'Mast cells activated via the Fc epsilon R1 and TL4 receptors the regulatory protein A20', INFLAMMATION RESEARCH, 54, pp. S139 - S140, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000205501600169&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Longo CR; Patel VI; Shrikhande GV; Scali ST; Csizmadia E; Daniel S; Sun DW; Grey ST; Arvelo MB; Ferran C, 2005, 'A20 protects mice from lethal radical hepatectomy by promoting hepatocyte proliferation via a p21^waf1-dependent mechanism', Hepatology, 42, pp. 156 - 164, http://dx.doi.org/10.1002/hep.20741

Mackay F; Sierro F; Grey ST; Gordon TP, 2005, 'The BAFF/APRIL system: an important player in systemic rheumatic diseases.', Current directions in autoimmunity, 8, pp. 243 - 265

Sutherland AP; Ng LG; Fletcher C; Shum B; Newton R; Grey S; Rolph MS; Mackay F; MacKay CR, 2005, 'BAFF augments certain Th1-associated inflammatory responses', Journal of Immunology, 174, pp. 5537 - 5544

Storz P; Doppler H; Ferran C; Grey S; Toker A, 2005, 'Functional dichotomy of A20 in apoptotic and necrotic cell death', Biochemical Journal, 387, pp. 47 - 55

Liuwantara D; Elliot M; Smit M; Walters S; Marino E; Gunton J; McShea A; Grey S, 2005, 'Islets participate in their own destruction by expressing pro-inflammatory and pro-apoptotic genes in the early stages of an inflammatory insult, balanced only by the expression of a limited set of anti-apoptotic genes', Tissue Antigens, 66, pp. 482 - 482

Walters S; Thaxton J; Marino E; Liuthuwana D; Sutherland AP; Mackay F; Grey S, 2005, 'Modulation of the alloimmune response by BAFF', Immunology and Cell Biology, 83, pp. A11 - A11

Walters S; Sutherland AP; Thaxton J; Liuwantara D; Marino E; Mackay F; Grey S, 2005, 'Modulation of the T cell dependent alloimmune response by BAFF', Tissue Antigens, 66, pp. 583 - 583

Marino E; Batten ML; Groom JR; Silveira PA; Walters S; Liuwantara D; Mackay F; Grey S, 2005, 'Temporal depletion of B cells, by selectively targeting BAFF, prevents diabetes in NOD mice', Tissue Antigens, 66, pp. 488 - 488

Daniel S; Arvelo MB; Patel VI; Longo CR; Shrikhande G; Shukri T; Mahiou J; Sun DW; Mottley C; Grey ST; Ferran C, 2004, 'A20 protects endothelial cells from TNF-, Fas-, and NK-mediated cell death by inhibiting caspase 8 activation', Blood, 104, pp. 2376 - 2384, http://dx.doi.org/10.1182/blood-2003-02-0635

Makhlouf L; Grey ST; Dong V; Csizmadia E; Arvelo MB; Auchincloss H; Ferran C; Sayegh MH, 2004, 'Depleting anti-CD4 monoclonal antibody cures new-onset diabetes, prevents recurrent autoimmune diabetes, and delays allograft rejection in nonobese diabetic mice', Transplantation, 77, pp. 990 - 997, http://dx.doi.org/10.1097/01.TP.0000118410.61419.59

Hartman M; Lu D; Kim M; Kociba G; Shukri T; Buteau J; Wang X; Frankel W; Guttridge D; Prentki M; Grey S; Ron D; Hai T, 2004, 'Role for activating transcription factor 3 in stress-induced beta-cellapoptosis', Molecular and Cellular Biology, 24, pp. 5721 - 5732, http://dx.doi.org/10.1128/MCB.24.13.5721-5732.2004

Krauss S; Zhang CY; Scorrano L; Dalgaard LT; St-Pierre J; Grey ST; Lowell BB, 2003, 'Superoxide-mediated activation of uncoupling protein 2 causes pancreatic β cell dysfunction', Journal of Clinical Investigation, 112, pp. 1831 - 1842, http://dx.doi.org/10.1172/JCI200319774

Longo CR; Arvelo MB; Patel VI; Daniel S; Mahiou J; Grey ST; Ferran C, 2003, 'A20 protects from CD40-CD40 ligand-mediated endothelial cell activation and apoptosis', Circulation, 108, pp. 1113 - 1118, http://dx.doi.org/10.1161/01.CIR.0000083718.76889.D0

Grey ST; Longo C; Shukri T; Patel VI; Csizmadia E; Daniel S; Arvelo MB; Tchipashvili V; Ferran C, 2003, 'Genetic engineering of a suboptimal islet graft with A20 preserves β cell mass and function', Journal of Immunology, 170, pp. 6250 - 6256, http://dx.doi.org/10.4049/jimmunol.170.12.6250

LONGO C; PATEL V; ARUELO M; DANIEL S; GREY S; FERRAN C, 2003, '42 A20 confers a proliferative advantage to hepatocytes and promotes liver regeneration', Hepatology, 38, pp. 175 - 175, http://dx.doi.org/10.1016/s0270-9139(03)80085-x

Arvelo MB; Cooper JT; Longo C; Daniel S; Grey ST; Mahiou J; Czismadia E; Abu-Jawdeh G; Ferran C, 2002, 'A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitis', Hepatology, 35, pp. 535 - 543, http://dx.doi.org/10.1053/jhep.2002.31309

Ross Laybutt D; Kaneto H; Hasenkamp W; Grey S; Jonas JC; Sgroi DC; Groff A; Ferran C; Bonner-Weir S; Sharma A; Weir GC, 2002, 'Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to β-cell survival during chronic hyperglycemia', Diabetes, 51, pp. 413 - 423, http://dx.doi.org/10.2337/diabetes.51.2.413

Grey ST, 2001, 'Signaling from the brink of danger', Trends in Immunology, 22, pp. 11, http://dx.doi.org/10.1016/S1471-4906(00)01777-4

Grey ST, 2000, 'Controlling the controllers of death.', Immunol Today, 21, pp. 469, http://dx.doi.org/10.1016/s0167-5699(00)01738-2

Grey ST; Arvelo MB; Hasenkamp W; Bach FH; Ferran C, 1999, 'A20 inhibits cytokine-induced apoptosis and nuclear factor κB-dependent gene activation in islets', Journal of Experimental Medicine, 190, pp. 1135 - 1145, http://dx.doi.org/10.1084/jem.190.8.1135

Tran TH; Grey S; Anrather J; Steinhäuslin F; Bach FH; Winkler H, 1998, 'Regulated and endothelial cell-specific expression of Fas ligand: An in vitro model for a strategy aiming at inhibiting xenograft rejection', Transplantation, 66, pp. 1126 - 1131, http://dx.doi.org/10.1097/00007890-199811150-00002

Soares MP; Lin Y; Anrather J; Csizmadia E; Takigami K; Sato K; Grey ST; Colvin RB; Choi AM; Poss KD; Bach FH, 1998, 'Expression of heme oxygenase-1 can determine cardiac xenograft survival', Nature Medicine, 4, pp. 1073 - 1077, http://dx.doi.org/10.1038/2063

Von Albertini M; Palmetshofer A; Kaczmarek E; Koziak K; Stroka D; Grey ST; Stuhlmeier KM; Robson SC, 1998, 'Extracellular ATP and ADP activate transcription factor NF-κB and induce endothelial cell apoptosis', Biochemical and Biophysical Research Communications, 248, pp. 822 - 829, http://dx.doi.org/10.1006/bbrc.1998.9055

Kopp CW; Grey ST; Siegel JB; McShea A; Vetr H; Wrighton CJ; Schulte Am Esch J; Bach FH; Robson SC, 1998, 'Expression of human thrombomodulin cofactor activity in porcine endothelial cells', Transplantation, 66, pp. 244 - 251, http://dx.doi.org/10.1097/00007890-199807270-00019

Ferran C; Stroka DM; Badrichani AZ; Cooper JT; Wrighton CJ; Soares M; Grey ST; Bach FH, 1998, 'A20 inhibits NF-κB activation in endothelial cells without sensitizing to tumor necrosis factor-mediated apoptosis', Blood, 91, pp. 2249 - 2258

Ferran C; Stroka DM; Badrichani AZ; Cooper JT; Wrighton CJ; Soares M; Grey ST; Bach FH, 1998, 'A20 Inhibits NF-κB Activation in Endothelial Cells Without Sensitizing to Tumor Necrosis Factor–Mediated Apoptosis', Blood, 91, pp. 2249 - 2258, http://dx.doi.org/10.1182/blood.v91.7.2249

Grey ST; Csizmadia V; Hancock WW, 1998, 'Differential effect of tumor necrosis factor-α on thrombomodulin gene expression by human monocytoid (THP-1) cells versus endothelial cells', International Journal of Hematology, 67, pp. 53 - 62, http://dx.doi.org/10.1016/s0925-5710(97)00080-7

Kopp CW; Grey S; Siegel JB; McShea A; Vetr H; Wrighton CJ; Hancock WW; Bach FH; Robson SC, 1998, 'EXPRESSION OF HUMAN THROMBOMODULIN COFACTOR ACTIVITY IN PORCINE AORTIC ENDOTHELIAL CELLS', Transplantation, 65, pp. S184 - S184, http://dx.doi.org/10.1097/00007890-199806270-00746

Kopp CW; Grey S; Siegel JB; McShea A; Vetr H; Wrighton CJ; Hancock WW; Bach FH; Robson SC, 1998, 'EXPRESSION OF HUMAN THROMBOMODULIN COFACTOR ACTIVITY IN PORCINE AORTIC ENDOTHELIAL CELLS.', Transplantation, 65, pp. 260 - 260, http://dx.doi.org/10.1097/00007890-199805131-00723

Ahmad MF; Stroka G; Grey S; Bach PH; Esmon CT; Hancock WW, 1997, 'Cloning of endothelial protein c receptor (EPCR) from human monocytes', FASEB Journal, 11

Siegel JB; Grey ST; Lesnikoski BA; Kopp CW; Soares M; Schulte Am Esch J; Bach FH; Robson SC, 1997, 'Xenogeneic endothelial cells activate human prothrombin', Transplantation, 64, pp. 888 - 896, http://dx.doi.org/10.1097/00007890-199709270-00017

Grey ST; Hancock WW, 1996, 'A physiologic anti-inflammatory pathway based on thrombomodulin expression and generation of activated protein C by human mononuclear phagocytes', Journal of Immunology, 156, pp. 2256 - 2263

Hancock WW; Grey ST; Hau L; Akalin E; Orthner C; Sayegh MH; Salem HH, 1995, 'Binding of activated protein c to a specific receptor on human mononuclear phagocytes inhibits intracellular calcium signaling and monocyte-dependent proliferative responses', Transplantation, 60, pp. 1525 - 1532, http://dx.doi.org/10.1097/00007890-199560120-00026

Grey ST; Tsuchida A; Hau H; Orthner CL; Salem HH; Hancock WW, 1994, 'Selective inhibitory effects of the anticoagulant activated protein C on the responses of human mononuclear phagocytes to LPS, IFN-γ, or phorbol ester', Journal of Immunology, 153, pp. 3664 - 3672

Bowles VM; Grey ST; Brandon MR, 1992, 'Cellular immune responses in the skin of sheep infected with larvae of Lucilia cuprina, the sheep blowfly', Veterinary Parasitology, 44, pp. 151 - 162, http://dx.doi.org/10.1016/0304-4017(92)90153-Z

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