By Professor Steven Krilis

Journal articles

Reed J; Giannakopoulos B; Jackson M; Krilis S; Gordon T, 2009, 'Ro 60 functions as a receptor for β2-glycoprotein I on apoptotic cells', Arthritis Care & Research, 60, pp. 860 - 869

Krilis S; Reed J; Giannakopoulos B; Jackson M; Gordon T, 2009, 'Ro60 Functions as a receptor for B2-glycoprotein I on apoptotic cells', Arthritis Care & Research, 60, pp. 985 - 994

Figtree M; Miyakis S; Jennings Z; Goh C; Konecny P; Krilis S, 2008, 'Factors Influencing Outcome in Cellulitis Admitted to Hospital and the Role of the Infectious Disease Physician', INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 12, pp. E240 - E240, http://dx.doi.org/10.1016/j.ijid.2008.05.599

Rahgozar S; Giannakopoulos B; Yan X; Wei J; Jian CQ; Gemmell R; Krilis SA, 2008, 'Beta2-glycoprotein I protects thrombin from inhibition by heparin cofactor II: Potentiation of this effect in the presence of anti-β2-glycoprotein I autoantibodies', Arthritis and Rheumatism, 58, pp. 1146 - 1155, http://dx.doi.org/10.1002/art.23387

Yu P; Passam F; Yu D; Denyer GS; Krilis S, 2008, 'beta 2-glycoprotein I inhibits vascular endothelial growth factor and basic fibroblast growth factor induced angiogenesis through its amino terminal domain', Journal of Thrombosis and Haemostasis, 6, pp. 1215 - 1223, http://dx.doi.org/10.1111/j.1538-7836.2008.03000.x

Krilis S; Rahgozar S; Giannakopoulos B; Qi JC; Gemmell R; Yan X; Wei J, 2008, 'Beta2- Glycoprotein I Protects Thrombin from Inhibition by Heparin Cofactor II', Arthritis Care & Research, 58, pp. 1146 - 1155

Krilis S, 2008, 'The antiphospholipid syndrome: molecular and diagnostic aspects', INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 30, pp. 18 - 19

Katsoulotos GP; Qi M; Qi JC; Tanaka K; Hughes WE; Molloy T; Adachi R; Stevens RL; Krilis S, 2008, 'The Diacylglcerol-dependent translocation of ras guanine nucleotide -releasing protein 4 inside a human mast cell line results in substantional phenotypic changes ,including expressions of interluken 13 recepter a2', The Journal of Biological Chemistry, 283, pp. 1610 - 1621

Rahgozar S; Yang Q; Giannakopoulos B; Yan X; Miyakis S; Krilis SA, 2007, 'Beta2-glycoprotein I binds thrombin via exosite I and exosite II: Anti-β2-glycoprotein I antibodies potentiate the inhibitory effect of β2-glycoprotein I on thrombin-mediated factor XIa generation', Arthritis and Rheumatism, 56, pp. 605 - 613, http://dx.doi.org/10.1002/art.22367

Giannakopoulos B; Shi T; Yan XK; Yu P; Berndt MC; Andrew R; Rivera J; Iverson GM; Cockerill KA; Linnik MD; Krilis S, 2007, 'Anti-beta(2)-glycoprotein I antibodies in complex with beta(2)-glycoprotein I can activate platelets via glycoprotein Ib-IX-V', Clinical and Experimental Rheumatology, 25, pp. 159 - 160

Krilis S, 2007, 'APL targets and mediated effects: PL-binding proteins B2GPI', Clinical and Experimental Rheumatology, 25, pp. 123 - 123

Rahgozar S; Yang Q; Giannakopoulos B; Yan XK; Miyakis S; Krilis S, 2007, 'Beta(2)-glycoprotein I binds thrombin via exosite I and exosite II Anti-beta(2)-glycoprotein I antibodies potentiate the inhibitory effect of beta(2)-glycoprotein I on thrombin-mediated factor XIa generation', Arthritis Care & Research, 56, pp. 605 - 613

Giannakopoulos B; Passam F; Rahgozar S; Krilis S, 2007, 'Current concepts on the pathogenesis of the antiphospholipid syndrome', Blood, 109, pp. 422 - 430

Katsoulotos GP; Tanaka K; Molloy TJ; Stevens RL; Krilis S, 2007, 'Ras guanine nucleotide releasing protein 4 (RasGRP4) dependent pathways and genes that reversibly control the development, phenotype, and function of human mast cells (MCs)', Journal of Allergy and Clinical Immunology, 119, pp. S50 - S50

Shi T; Giannakopoulos B; Yan X; Yu P; Berndt MC; Andrews RK; Rivera J; Iverson GM; Cockerill KA; Linnik MD; Krilis SA, 2006, 'Anti-β2-glycoprotein I antibodies in complex with β2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V', Arthritis and Rheumatism, 54, pp. 2558 - 2567, http://dx.doi.org/10.1002/art.21968

Shi T; Giannakopoulos B; Yan XK; Yu P; Berndt MC; Andrews RK; Rivera J; Iverson M; Cockerill KA; Linnik MD; Krilis S, 2006, 'Anti-Beta2-Glycoprotein I Antibodies in Complex With Beta2-Glycoprotein I Can Activate Platelets in a Dysregulated Manner Via Glycoprotein Ib-IX-V', Arthritis Care & Research, 54, pp. 2558 - 2567

Qi J; Wang JQ; Mandadi S; Tanaka K; Roufogalis BD; Madigan MC; Lai K; Yan F; Chong BH; Stevens RL; Krilis S, 2006, 'Human and mouse mast cells use the Tetraspanin CD9 as an alternate Interleukin 16 receptor', Blood, 107, pp. 135 - 142

Miyakis S; Lockshin M; Atsumi T; Branch D; Brey R; Cervera R; Derksen R; Tincani A; Vlachoyiannopoulos P; Krilis S, 2006, 'International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)', Journal of Thrombosis and Haemostasis, 4, pp. 295 - 306

Miyakis S; Lockshin M; Atsumi T; Branch D; Brey R; Cervera R; Derksen R; De Groot P; Koike T; Meroni PL; Reber G; Shoenfeld Y; Tincani A; Vlachoyiannopoulos P; Krilis S, 2006, 'International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)', Journal of Thrombosis and Haemostasis, 4, pp. 295 - 306

Kordjian N; Donaldson A; Murrell DF; Krilis S, 2005, 'A case of desquamating rash associated with methadone use', Medical Journal of Australia, 182, pp. 76 - 77

Shi T; Giannakopoulos B; Iverson M; Cockerill KA; Linnik MD; Krilis S, 2005, 'Domain V of B2-Glycoprotein I Binds Factor XI/XIa and Is Cleaved of Lys317-Thr318', The Journal of Biological Chemistry, 280, pp. 907 - 912

Cai H; Song C; Lim IG; Krilis S; Geczy C; McNeil HP, 2005, 'Importance of C-Reactive Protein in Regulating Monocyte Tissue Factor Expresion in Patients with Inflammatory Rhumatic Diseases', The Journal of Rheumatology, 32, pp. 1224 - 1231

Andreson D; Donaldson A; Choo L; Knox A; Klaassen M; Ursic CM; Vonthethoff LW; Krilis S; Konecny P, 2005, 'Multifocal cutaneous mucormycosis complicating polymicrobial wound infections in a tsunami survivor from Sri Lanka', Lancet, 365, pp. 876 - 878

Di Simone N; Raschi E; Testoni C; Castellani R; D Asta M; Shi T; Krilis S; Caruso A; Luigi MP, 2005, 'Pathogenic role of anTi-beta 2-glycoprotein I in antiphospholipid-associated with fetal loss: characterisation of beta 2-glycoprotein I binding to trophoblast cells and functional effects of anti-beta 2-gylprotein I antiobodies in vitro', Annals of the Rheumatic Diseases, 64, pp. 462 - 467

Yasuda S; Morokawa N; Wong GW; Rossi A; Madhusudhan MS; Sali A; Askew YS; Adachi R; Silverman GA; Krilis S; Stevens RL, 2005, 'Urokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase /PRSS22', Blood, 105, pp. 3893 - 3901

Ho LH; Ruffin RE; Murgia C; Li LX; Krilis SA; Zalewski PD, 2004, 'Labile zinc and zinc transporter ZnT4 in mast cell granules: Role in regulation NF-KB translocation', JOURNAL OF IMMUNOLOGY, 172, pp. 7750 - 7760, http://dx.doi.org/10.4049/jimmunol.172.12.7750

Shi T; Iverson GM; Qi JC; Cockerill KA; Linnik MD; Konecny P; Krilis SA, 2004, 'β2-Glycoprotein I binds factor XI and inhibits its activation by thrombin and factor XIIa: Loss of inhibition by clipped β2-glycoprotein I', Proceedings of the National Academy of Sciences of the United States of America, 101, pp. 3939 - 3944, http://dx.doi.org/10.1073/pnas.0400281101

Passam FH; Krilis SA, 2004, 'Laboratory tests for the antiphospholipid syndrome: Current concepts', Pathology, 36, pp. 129 - 138, http://dx.doi.org/10.1080/00313020410001671966

Yang Q; Shi T; Cheyne B; Giannakopoulos B; Krilis S, 2004, 'Anti-beta(2) glycoprotein I antibodies potentiate the inhibitory effects of beta(2)glycoprotein I on the activation of FXI by FIIa: Effect of clipped beta(2) glycoprotein I', Thrombosis Research, 114, pp. 608 - 608

Bester C; Shi T; Iverson GM; Cockerill KA; Linnik MD; Konecny P; Krilis S, 2004, 'B-2-glycoprotein I binds factor XI by its C-terminal domain and inhibits its activation by thrombin and factor XIIA. Plasmin cleavage of B-2-glycoprotein I abolishes its inhibition of factor XIIA activation of factor XI', Thrombosis Research, 114, pp. 608 - 609

Shi T; Iverson M; Qi JC; Cockerill KA; Linnik MD; Konecny P; Krilis S, 2004, 'B2Glycoprotein I binds Factor XI and inhibits its activation by thrombin and Factor XIIa. Loss of Inhibition by Clipped B2Glycoprotein I.', Proceedings of the National Academy of Sciences of the United States of America, 101, pp. 3939 - 3944

Miyakis S; Giannakopoulos B; Krilis S, 2004, 'Beta 2-Glycoprotein I-function in health and disease', Thrombosis Research, 114, pp. 335 - 346

Miyakis S; Robertson SA; Krilis S, 2004, 'Beta-2 glycoprotein I and its role in antiphospholipid syndrome-lessons from knockout mice', Clinical Immunology, 112, pp. 136 - 143

Robertson SA; Roberts CT; Beijering E; Pensa K; Sheng YH; Shi T; Krilis S, 2004, 'Effect of B2Glycoprotein I null mutation on reproductive outcome and antiphospholipid antibody-mediated pregnancy pathology in mice', Molecular Human Reproduction, pp. 1 - 8

Shi T; Robertson SA; Roberts CT; Beijering D; Pensa K; Sheng YH; Krilis S, 2004, 'Effect of beta(2)-glycoprotein I null mutation on reproductive outcome and antiphospholipid antibody-mediated pregnancy pathology in mice', Thrombosis Research, 114, pp. 608 - 608

Robertson SA; Roberts CT; van Beijering E; Pensa K; Sheng YH; Shi T; Krilis S, 2004, 'Effect of beta(2)-glycoprotein I null mutation on reproductive outcomea and antiphospholipid antibody-mediated pregnancy pathology in mice', Molecular Human Reproduction, 10, pp. 409 - 416

Ho LH; Ruffin RE; Murgia C; Li L; Krilis S; Zalewski P, 2004, 'Labile zinc and zinc transporter ZnT4 in mast cell granules: role in regulation of caspase activation and NF-kappaB translocation', Journal of Immunology, 172, pp. 7750 - 7760

Passam F; Krilis S, 2004, 'Laboratory tests for the antiphospholipid syndrome', Pathology, 36, pp. 129 - 138

Renaudineau Y; Dugue C; Arvieux J; Perraut R; Krilis S; Youinou P, 2004, 'No correlations between anti-endothelial cell and anti phospholipid antibodies in a cohort of 176 leprosy patients', Thrombosis Research, 114, pp. 611 - 611

Yasuda S; Wong GW; Rossi A; Madhusudhan MS; Morokawa N; Sali A; Krilis S; Stevens RL, 2004, 'Urokinase-type plasminogen activator is a preferred substrate of thehuman epithelium serine protease tryptase epsilon/PRSS22', Federation of American Societies for Experimantal Biology Journal, 18, pp. A793 - A793

Reddel SW; Wang YX; Krilis SA, 2003, 'Anti-β2-glycoprotein I autoantibodies require an antigen density threshold, consistent with divalent binding', Lupus, 12, pp. 37 - 45, http://dx.doi.org/10.1191/0961203303lu280oa

Li Z; Krilis SA, 2003, 'Anti-β2-glycoprotein I antibodies and the antiphospholipid syndrome', Autoimmunity Reviews, 2, pp. 229 - 234, http://dx.doi.org/10.1016/S1568-9972(03)00015-6

Krilis S, 2003, 'Anti-.2-glycoprotein I antibodies and the antiphospholipid syndrome', Autoimmunity Reviews, 2, pp. 229 - 234

Krilis S; Reddel SW; Wang YX, 2003, 'Anti-B2-glycoprotein I autoantibodiese require an antigen density threshold, consistent with divalent binding', Lupus, 12, pp. 37 - 45

Krilis S; Lockshin M; Tenedios F; Petri M; McCarty G; Forastiero R; Tincani A; Erkan D; Khamashta MA; Shoenfeld Y, 2003, 'Cardiac disease in the antiphospholipid syndrome: recommendations for treatment. Committee consensus report', Lupus, 12, pp. 518 - 523

Krilis S; Qi JC; Konecny P; Wang J, 2003, 'Hemopoietic Cells with Features of the Mast Cell and Basophil Lineages and their Potential Role in Allergy', Current Drug Targets, 2, pp. 293 - 302

Qi JC; Krilis S, 2003, 'MCs/Basophils in Human Blood', ACI International, 15, pp. 11 - 16

Krilis S; Qi JC, 2003, 'MCs/Basophils in human Blood - What are they and how did they get there?', Allergy and Clinical Immunology International, 15, pp. 11 - 17

Wong GW; Foster PS; Yasuda S; Qi JC; Mahalingam S; Mellor EA; Katsoulotos G; Li X; Boyce JA; Krilis SA; Stevens RL, 2002, 'Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase γ: TMT is an exocytosed mast cell protease that induces airway hyperresponsiveness in vivo via an interleukin-13/interleukin-4 receptor α/signal transducer and activator of transcription (STAT) 6-dependent pathway', Journal of Biological Chemistry, 277, pp. 41906 - 41915, http://dx.doi.org/10.1074/jbc.M205868200

Guerin J; Sheng Y; Reddel S; Michael Iverson G; Chapman MG; Krilis SA, 2002, 'Heparin inhibits the binding of β2-glycoprotein I to phospholipids and promotes the plasmin-mediated inactivation of this blood protein. Elucidation of the consequences of the two biological events in patients with the anti-phospholipid syndrome', Journal of Biological Chemistry, 277, pp. 2644 - 2649, http://dx.doi.org/10.1074/jbc.M110176200

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