Select Publications
Journal articles
2024, 'Domain 5 of Beta 2 glycoprotein I: Friend or foe in health? Context matters', Clinical Immunology, 265, http://dx.doi.org/10.1016/j.clim.2024.110282
,2024, 'Development of the 2023 ACR/EULAR Antiphospholipid Syndrome Classification Criteria, Phase III-D Report: Multicriteria Decision Analysis', Arthritis Care and Research, http://dx.doi.org/10.1002/acr.25415
,2023, 'Anti–Neutrophil Extracellular Trap Antibodies in Antiphospholipid Antibody–Positive Patients: Results From the Antiphospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking Clinical Database and Repository', Arthritis and Rheumatology, 75, pp. 1407 - 1414, http://dx.doi.org/10.1002/art.42489
,2023, 'Associations Among Antiphospholipid Antibody Types, Isotypes, and Titers: An AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) Study', Laboratory Investigation, 103, http://dx.doi.org/10.1016/j.labinv.2023.100147
,2023, 'Fluctuation of Anti–Domain 1 and Anti–β
2022, 'Βeta-2-glycoprotein I exerts antithrombotic function through its domain V in mice', Journal of Autoimmunity, 126, http://dx.doi.org/10.1016/j.jaut.2021.102747
,2021, 'Development of a New International Antiphospholipid Syndrome Classification Criteria Phase I/II Report: Generation and Reduction of Candidate Criteria', Arthritis Care and Research, 73, pp. 1490 - 1501, http://dx.doi.org/10.1002/acr.24520
,2021, 'Clinical relevance of nitrated beta 2-glycoprotein I in antiphospholipid syndrome: Implications for thrombosis risk', Journal of Autoimmunity, 122, http://dx.doi.org/10.1016/j.jaut.2021.102675
,2020, 'Free Thiol β2-GPI (β-2-Glycoprotein-I) Provides a Link Between Inflammation and Oxidative Stress in Atherosclerotic Coronary Artery Disease', Arteriosclerosis, Thrombosis, and Vascular Biology, 40, pp. 2794 - 2804, http://dx.doi.org/10.1161/ATVBAHA.120.315156
,2020, 'Cluster analysis for the identification of clinical phenotypes among antiphospholipid antibody-positive patients from the APS ACTION Registry', Lupus, 29, pp. 1353 - 1363, http://dx.doi.org/10.1177/0961203320940776
,2019, 'The comparison of real world and core laboratory antiphospholipid antibody ELISA results from antiphospholipid syndrome alliance for clinical trials & international networking (APS ACTION) clinical database and repository analysis', Thrombosis Research, 175, pp. 32 - 36, http://dx.doi.org/10.1016/j.thromres.2019.01.010
,2018, 'Dual roles of different redox forms of complement factor H in protecting against age related macular degeneration', Free Radical Biology and Medicine, 129, pp. 237 - 246, http://dx.doi.org/10.1016/j.freeradbiomed.2018.09.034
,2018, 'Oxidative post-translational modification of βeta 2-glycoprotein I in the pathophysiology of the anti-phospholipid syndrome', Free Radical Biology and Medicine, 125, pp. 98 - 103, http://dx.doi.org/10.1016/j.freeradbiomed.2018.03.048
,2017, 'Βeta 2-glycoprotein i protects mice against gram-negative septicaemia in a sexually dimorphic manner', Scientific Reports, 7, pp. 8201, http://dx.doi.org/10.1038/s41598-017-07945-8
,2017, 'Experimental arthritis is dependent on mouse mast cell protease-5', Journal of Biological Chemistry, 292, pp. 5392 - 5404, http://dx.doi.org/10.1074/jbc.M116.773416
,2017, 'Nitration of tyrosines in complement factor H domains alters its immunological activity and mediates a pathogenic role in age related macular degeneration', Oncotarget, 8, pp. 49016 - 49032, http://dx.doi.org/10.18632/oncotarget.14940
,2017, 'β2GPI exerts an anti-obesity effect in female mice by inhibiting lipogenesis and promoting lipolysis', Oncotarget, 8, pp. 92652 - 92666, http://dx.doi.org/10.18632/oncotarget.21536
,2017, 'Development of Novel Assays for Quantitation of Total and Free Thiol Beta 2 Glycoprotein I', Heart, Lung and Circulation, 26, pp. S55 - S55, http://dx.doi.org/10.1016/j.hlc.2017.06.027
,2016, 'Posttranslational forms of beta 2-glycoprotein I in the pathogenesis of the antiphospholipid syndrome', Thrombosis Journal, 14, pp. 20, http://dx.doi.org/10.1186/s12959-016-0115-z
,2016, 'Gram negative bacterial inflammation ameliorated by the plasma protein beta 2-Glycoprotein I', Scientific Reports, 6, pp. 33656, http://dx.doi.org/10.1038/srep33656
,2016, 'CD117+ dendritic and mast cells are dependent on RasGRP4 to function as accessory cells for optimal natural killer cell-mediated responses to lipopolysaccharide', PLoS ONE, 11, pp. e0151638, http://dx.doi.org/10.1371/journal.pone.0151638
,2016, 'The fifth domain of beta 2 glycoprotein I protects from natural IgM mediated cardiac ischaemia reperfusion injury', PLoS ONE, 11, pp. e0152681, http://dx.doi.org/10.1371/journal.pone.0152681
,2016, 'Do Beta 2-Glycoprotein i Disulfide Bonds Protect the Human Retina in the Setting of Age-Related Macular Degeneration?', Antioxidants and Redox Signaling, 24, pp. 32 - 38, http://dx.doi.org/10.1089/ars.2014.6052
,2015, 'Improved assay for quantifying a redox form of angiotensinogen as a biomarker for pre-eclampsia: A case-control study', PLoS ONE, 10, pp. e0135905, http://dx.doi.org/10.1371/journal.pone.0135905
,2014, 'Laboratory methods to detect antiphospholipid antibodies', Hematology (United States), 2014, pp. 321 - 328, http://dx.doi.org/10.1182/asheducation-2014.1.321
,2014, 'Importance of mast cell Prss31/transmembrane tryptase/tryptase-γ in lung function and experimental chronic obstructive pulmonary disease and colitis', Journal of Biological Chemistry, 289, pp. 18214 - 18227, http://dx.doi.org/10.1074/jbc.M114.548594
,2014, 'In APS, two A1's are better than one!', Blood, 123, pp. 955 - 956, http://dx.doi.org/10.1182/blood-2013-12-542506
,2014, 'Deletion of the antiphospholipid syndrome autoantigen β
2014, 'Development of mast cells and importance of their tryptase and chymase serine proteases in inflammation and wound healing', , 122, pp. 211 - 252, http://dx.doi.org/10.1016/B978-0-12-800267-4.00006-7
,2013, 'POST TRANSLATIONALLY MODIFIED COMPLEMENT FACTOR H IN AGE RELATED MACULAR DEGENERATION', CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 41, pp. 17 - 17, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000329507100022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2013, 'Intracoronary upregulation of platelet extracellular matrix metalloproteinase inducer (CD147) in coronary disease', International Journal of Cardiology, 166, pp. 716 - 721, http://dx.doi.org/10.1016/j.ijcard.2011.11.093
,2013, 'The Pathogenesis of the Antiphospholipid Syndrome', New England Journal of Medicine, 368, pp. 1033 - 1044
,2012, 'Factor XI is a substrate for oxidoreductases: Enhanced activation of reduced FXI and its role in antiphospholipid syndrome thrombosis.', Journal of Autoimmunity, 39, pp. 121 - 129, http://dx.doi.org/10.1016/j.jaut.2012.05.005
,2012, 'Post-translational oxidative modification of â2-glycoprotein I and its role in the pathophysiology of the antiphospholipid syndrome.', Autoimmunity Reviews, 11, pp. 779 - 780, http://dx.doi.org/10.1016/j.autrev.2011.12.007
,2012, 'Ras guanine nucleotide releasing protein-4 (RasGRP4) involvement in experimental arthritis and colitis.', The Journal of Biological Chemistry, 287, pp. 20047 - 20055, http://dx.doi.org/10.1074/jbc.M112.360388
,2011, 'Laboratory Testing for Antiphospholipid Syndrome', , pp. 985 - 1000, http://dx.doi.org/10.1016/B978-0-12-374994-9.10052-X
,2011, 'Molecular pathophysiology of the antiphospholipid syndrome: the role of oxidative posttranslational modification of beta 2 glycoprotein I', JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 9, pp. 715 - 715, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208992803015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2011, 'Essential role for mast cell tryptase in acute experimental colitis.', Proceedings of the National Academy of Sciences of the United States of America, 108, pp. 290 - 295, http://dx.doi.org/10.1073/pnas.1005758108
,2011, 'Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: report of a task force at the 13th International Congress on antiphospholipid antibodies.', Lupus, 20, pp. 206 - 218, http://dx.doi.org/10.1177/0961203310395803
,2011, 'Intracoronary shear-related up-regulation of platelet P-selectin and platelet monocyte aggregation despite the use of aspirin and clopidogral', Blood, 117, pp. 11 - 20, http://dx.doi.org/10.1182/blood-2010-04-278812
,2011, 'New insights into the biology and pathobiology of beta2-glycoprotein I.', Current Rheumatology Reports, 13, pp. 90 - 95, http://dx.doi.org/10.1007/s11926-010-0151-9
,2011, 'Redox control of â2-glycoprotein I-von Willebrand factor interaction by thioredoxin-1.', Journal of Thrombosis and Haemostasis, 8, pp. 1754 - 1762, http://dx.doi.org/10.1111/j.1538-7836.2010.03944.x
,2010, 'Naturally occurring free thiols within β2-glycoprotein I in vivo: Nitrosylation, redox modification by endothelial cells, and regulation of oxidative stress-induced cell injury', Blood, 116, pp. 1961 - 1970, http://dx.doi.org/10.1182/blood-2009-04-215335
,2010, 'Beta 2 glycoprotein I is a substrate of thiol oxidoreductases', Blood, 116, pp. 1995 - 1997, http://bloodjournal.hematologylibrary.org/cgi/content/citation/116/11/1995
,2010, 'In vivo modulation of angiogenesis by beta 2 glycoprotein I.', Journal of Autoimmunity, 35, pp. 232 - 240
,2010, 'Q fever cholecystitis in an unvaccinated butcher diagnosed by gallbladder plymerase chain reaction', Vector - Borne and Zoonotic Diseases, 10, pp. 421 - 423, http://dx.doi.org/10.1089/vbz.2008.0209
,2010, 'Risk Stratification and outcome of Cellulitis admitted to hospital', Journal of Infection, 60, pp. 431 - 439
,2009, 'Dapsone hypersensitivity syndrome causing disseminated intravascular coagulation', BMJ Case Reports, http://dx.doi.org/10.1136/bcr.11.2008.1257
,2009, 'How I treat the antiphospholipid syndrome', Blood, 114, pp. 2020 - 2030
,2009, 'How we diagnose the antiphospholipid syndrome', Blood, 113, pp. 985 - 994
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