Select Publications

Journal articles

Passam FH; Chen G; Chen VM; Qi M; Krilis SA; Giannakopoulos B, 2022, 'Βeta-2-glycoprotein I exerts antithrombotic function through its domain V in mice', Journal of Autoimmunity, vol. 126,

Barbhaiya M; Zuily S; Ahmadzadeh Y; Amigo MC; Avcin T; Bertolaccini M; Branch DW; de Jesus G; Devreese KMJ; Frances C; Garcia D; Guillemin F; Levine SR; Levy RA; Lockshin MD; Ortel T; Seshan SV; Tektonidou M; Wahl D; Willis R; Naden R; Costenbader K; Erkan D; Agmon-Levin N; Aguilar C; Alba P; Alpan O; Ambrozic A; Amoura Z; Andrade D; Andrade L; Appenzeller S; Esen BA; Atsumi T; Berkun Y; Cabral A; Canaud G; Cervera R; Chen P; Chighizola C; Cimaz R; Cohen H; Costedoat-Chalumeau N; Crowther M; Cuadrado MJ; de Groot PG; de Moerloose P; Derksen R; Diz-Kucukkaya R; Dörner T; Fortin P; Giannakopoulos B; Gómez-Puerta JA; Gonzalez EB; Inanc M; Kenet G; Khamashta M; Kriegel M; Krilis S; Laskin C; Massicotte P; McCarty G; Meroni PL; Mikdashi J; Myones B; Pengo V; Petri M; Roubey R; Sammaritano L; Sanna G; Sciascia S; Signorelli F; Soybilgic A; Tincani A; Woller S; Yelnik C, 2021, 'Development of a New International Antiphospholipid Syndrome Classification Criteria Phase I/II Report: Generation and Reduction of Candidate Criteria', Arthritis Care and Research, vol. 73, pp. 1490 - 1501,

Krilis M; Qi M; Ioannou Y; Zhang JY; Ahmadi Z; Wong JWH; Vlachoyiannopoulos PG; Moutsopoulos HM; Koike T; Sturgess AD; Chong BH; Krilis SA; Giannakopoulos B, 2021, 'Clinical relevance of nitrated beta 2-glycoprotein I in antiphospholipid syndrome: Implications for thrombosis risk', Journal of Autoimmunity, vol. 122, pp. 102675,

Weaver JC; Ullah I; Qi M; Giannakopoulos B; Rye KA; Kockx M; Kritharides L; Krilis SA, 2020, 'Free Thiol β2-GPI (β-2-Glycoprotein-I) Provides a Link Between Inflammation and Oxidative Stress in Atherosclerotic Coronary Artery Disease', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 40, pp. 2794 - 2804,

Zuily S; Clerc-Urmès I; Bauman C; Andrade D; Sciascia S; Pengo V; Tektonidou MG; Ugarte A; Gerosa M; Michael Belmont H; Zamorano MAA; Fortin P; Ji L; Efthymiou M; Cohen H; Branch DW; Jesus GRD; Nalli C; Petri M; Rodriguez E; Cervera R; Knight JS; Atsumi T; Willis R; Bertolaccini ML; Vega J; Wahl D; Erkan D; Pons-Estel G; Giannakopoulos B; Krilis S; de Jesus G; Levy R; Fortin PF; Zhang Z; Andreoli L; Tincani A; Chighizola CB; Meroni P; Banzato A; Davis S; Amengual O; Uthman I; Limper M; de Groot P; Irastorza GR; Rodríguez-Pintó I; Cuadrado MJ; Lopez-Pedrera R; Artim-Esen B; Inanc M; Khamashta M; Mackie I; Sanna G; Knight J; Roubey R; Ortel T; Gonzalez E; Belmont M; Levine S; Rand J; Barbhaiya M; Salmon J; Lockshin M, 2020, 'Cluster analysis for the identification of clinical phenotypes among antiphospholipid antibody-positive patients from the APS ACTION Registry', Lupus, vol. 29, pp. 1353 - 1363,

Sciascia S; Willis R; Pengo V; Krilis S; Andrade D; Tektonidou MG; Ugarte A; Chighizola C; Branch DW; Levy RA; Nalli C; Fortin PR; Petri M; Rodriguez E; Rodriguez-Pinto I; Atsumi T; Nascimento I; Rosa R; Banzato A; Erkan D; Cohen H; Efthymiou M; Mackie I; Bertolaccini ML, 2019, 'The comparison of real world and core laboratory antiphospholipid antibody ELISA results from antiphospholipid syndrome alliance for clinical trials & international networking (APS ACTION) clinical database and repository analysis', Thrombosis Research, vol. 175, pp. 32 - 36,

Krilis M; Qi M; Qi J; Wong JWH; Guymer R; Liew G; Hunyor AP; Madigan M; McCluskey P; Weaver J; Krilis SA; Giannakopoulos B, 2018, 'Dual roles of different redox forms of complement factor H in protecting against age related macular degeneration', Free Radical Biology and Medicine, vol. 129, pp. 237 - 246,

Weaver JC; Krilis SA; Giannakopoulos B, 2018, 'Oxidative post-translational modification of βeta 2-glycoprotein I in the pathophysiology of the anti-phospholipid syndrome', Free Radical Biology and Medicine, vol. 125, pp. 98 - 103,

El-Assaad F; Qi M; Gordon AK; Qi J; Dong S; Passam F; Weaver JC; Giannakopoulos B; Krilis SA, 2017, 'Βeta 2-glycoprotein i protects mice against gram-negative septicaemia in a sexually dimorphic manner', Scientific Reports, vol. 7,

Stevens RL; McNeil HP; Wensing LA; Shin K; Wong GW; Hansbro PM; Krilis SA, 2017, 'Experimental arthritis is dependent on mouse mast cell protease-5', Journal of Biological Chemistry, vol. 292, pp. 5392 - 5404,

Krilis M; Qi M; Madigan MC; Wong JWH; Abdelatti M; Guymer RH; Whitelock J; McCluskey P; Zhang P; Qi J; Hunyor AP; Krilis SA; Giannakopoulos B, 2017, 'Nitration of tyrosines in complement factor H domains alters its immunological activity and mediates a pathogenic role in age related macular degeneration', Oncotarget, vol. 8, pp. 49016 - 49032,

Dong S; Qi M; Wang Y; Chen L; Weaver JC; Krilis SA; Giannakopoulos B, 2017, 'β2GPI exerts an anti-obesity effect in female mice by inhibiting lipogenesis and promoting lipolysis', Oncotarget, vol. 8, pp. 92652 - 92666,

Ullah I; Qi M; Qi J; Giannakopoulos B; Weaver J; Krilis S, 2017, 'Development of Novel Assays for Quantitation of Total and Free Thiol Beta 2 Glycoprotein I', Heart, Lung and Circulation, vol. 26, pp. S55 - S55,

El-Assaad F; Krilis SA; Giannakopoulos B, 2016, 'Posttranslational forms of beta 2-glycoprotein I in the pathogenesis of the antiphospholipid syndrome', Thrombosis Journal, vol. 14,

Zhou S; Chen G; Qi M; El-Assaad F; Wang Y; Dong S; Chen L; Yu D; Weaver JC; Beretov J; Krilis SA; Giannakopoulos B, 2016, 'Gram negative bacterial inflammation ameliorated by the plasma protein beta 2-Glycoprotein I', Scientific Reports, vol. 6,

Zhou S; Tanaka K; O'Keeffe M; Qi M; El-Assaad F; Weaver JC; Chen G; Weatherall C; Wang Y; Giannakopoulos B; Chen L; Yu DM; Hamilton MJ; Wensing LA; Stevens RL; Krilis SA, 2016, 'CD117+ dendritic and mast cells are dependent on RasGRP4 to function as accessory cells for optimal natural killer cell-mediated responses to lipopolysaccharide', PLoS ONE, vol. 11,

Zhang P; Weaver JC; Chen G; Beretov J; Atsumi T; Qi M; Bhindi R; Qi JC; Madigan MC; Giannakopoulos B; Krilis SA, 2016, 'The fifth domain of beta 2 glycoprotein I protects from natural IgM mediated cardiac ischaemia reperfusion injury', PLoS ONE, vol. 11,

Qi M; Abdelatti M; Krilis M; Madigan MC; Weaver J; Guymer RH; McCluskey P; Wang Y; Zhou S; Krilis SA; Giannakopoulos B, 2016, 'Do Beta 2-Glycoprotein i Disulfide Bonds Protect the Human Retina in the Setting of Age-Related Macular Degeneration?', Antioxidants and Redox Signaling, vol. 24, pp. 32 - 38,

Rahgozar S; Amirian T; Qi M; Shahshahan Z; Entezar-E-Ghaem M; Tehrani HG; Miroliaei M; Krilis SA; Giannakopoulos B, 2015, 'Improved assay for quantifying a redox form of angiotensinogen as a biomarker for pre-eclampsia: A case-control study', PLoS ONE, vol. 10,

Krilis SA; Giannakopoulos B, 2014, 'Laboratory methods to detect antiphospholipid antibodies', Hematology (United States), vol. 2014, pp. 321 - 328,

Hansbro PM; Hamilton MJ; Fricker M; Gellatly SL; Jarnicki AG; Zheng D; Frei SM; Wong GW; Hamadi S; Zhou S; Foster PS; Krilis SA; Stevens RL, 2014, 'Importance of mast cell Prss31/transmembrane tryptase/tryptase-γ in lung function and experimental chronic obstructive pulmonary disease and colitis', Journal of Biological Chemistry, vol. 289, pp. 18214 - 18227,

Giannakopoulos B; Krilis S, 2014, 'In APS, two A1's are better than one!', Blood, vol. 123, pp. 955 - 956,

Giannakopoulos B; Mirarabshahi P; Qi M; Weatherall C; Qi JC; Tanaka K; Millar E; Vonthethoff L; Gatto D; Spielman D; Krilis SA, 2014, 'Deletion of the antiphospholipid syndrome autoantigen β2- glycoprotein i potentiates the lupus autoimmune phenotype in a toll-like receptor 7-mediated murine model', Arthritis and Rheumatology, vol. 66, pp. 2270 - 2280,

Douaiher J; Succar J; Lancerotto L; Gurish MF; Orgill DP; Hamilton MJ; Krilis SA; Stevens RL, 2014, 'Development of mast cells and importance of their tryptase and chymase serine proteases in inflammation and wound healing', Advances in Immunology, vol. 122, pp. 211 - 252,

Krilis M; Mao Q; Madigan M; Wong J; Abulatti M; Guymer R; McCluskey P; Zhang P; Qi J; Krilis S; Giannakopoulos B, 2013, 'POST TRANSLATIONALLY MODIFIED COMPLEMENT FACTOR H IN AGE RELATED MACULAR DEGENERATION', CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, vol. 41, pp. 17 - 17,

Yong A; Pennings G; Wong C; Javadzadegan A; Brieger D; Lowe H; Qi M; Behnia M; Krilis S; Kritharides L, 2013, 'Intracoronary upregulation of platelet extracellular matrix metalloproteinase inducer (CD147) in coronary disease', International Journal of Cardiology, vol. 166, pp. 716 - 721,

Giannakopoulos B; Krilis S, 2013, 'The Pathogenesis of the Antiphospholipid Syndrome', New England Journal of Medicine, vol. 368, pp. 1033 - 1044,

Giannakopoulos B; Gao L; Qi M; Wong JW; Yu D; Vlachoyiannopoulos P; Moutsopoulos HM; Atsumi T; Koike T; Hogg PJ; Qi JC; Krilis S, 2012, 'Factor XI is a substrate for oxidoreductases: Enhanced activation of reduced FXI and its role in antiphospholipid syndrome thrombosis.', Journal of Autoimmunity, vol. 39, pp. 121 - 129,

Mirarabshahii P; Abdelatti A; Krilis S, 2012, 'Post-translational oxidative modification of â2-glycoprotein I and its role in the pathophysiology of the antiphospholipid syndrome.', Autoimmunity Reviews, vol. 11, pp. 779 - 780,

Adachi R; Krilis S; Nigrovic P; Hamilton MJ; Chung K; Thakurdas SM; Boyce JA; Anderson P; Stevens RL, 2012, 'Ras guanine nucleotide releasing protein-4 (RasGRP4) involvement in experimental arthritis and colitis.', The Journal of Biological Chemistry, vol. 287, pp. 20047 - 20055,

Ioannou Y; Krilis SA, 2011, 'Laboratory Testing for Antiphospholipid Syndrome', Systemic Lupus Erythematosus, pp. 985 - 1000,

Krilis S; Passam F; Giannakopoulos B; Mirarabshahi P, 2011, 'Molecular pathophysiology of the antiphospholipid syndrome: the role of oxidative posttranslational modification of beta 2 glycoprotein I', JOURNAL OF THROMBOSIS AND HAEMOSTASIS, vol. 9, pp. 715 - 715,

Hamilton MJ; Sinnamon MJ; Lyng GD; Glickman JN; Wang X; Xing W; Krilis S; Blumberg RS; Adachi R; Lee DM; Stevens RL, 2011, 'Essential role for mast cell tryptase in acute experimental colitis.', Proceedings of the National Academy of Sciences of the United States of America, vol. 108, pp. 290 - 295,

Ruiz-irastorza G; Cuadrado MJ; Brey R; Crowther M; Derksen R; Erkan D; Krilis S; Machin S; Pengo V; Pierangeli S; Tektonidou M; Khamashta MA, 2011, 'Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: report of a task force at the 13th International Congress on antiphospholipid antibodies.', Lupus, vol. 20, pp. 206 - 218,

Yong A; Pennings GJ; Chang M; Hamzah A; Chung T; Qi M; Brieger D; Behnia M; Krilis S; Ng MK; Lowe HC; Kritharides L, 2011, 'Intracoronary shear-related up-regulation of platelet P-selectin and platelet monocyte aggregation despite the use of aspirin and clopidogral', Blood, vol. 117, pp. 11 - 20,

Giannakopoulos B; Mirarabshahi P; Krilis S, 2011, 'New insights into the biology and pathobiology of beta2-glycoprotein I.', Current Rheumatology Reports, vol. 13, pp. 90 - 95,

Passam F; Rahgozar S; Qi M; Raftery MJ; Wong JWH; Tanaka K; Ioannou Y; Zhang JY; Gemmell R; Qi JC; Giannakopoulos B; Hughes WE; Hogg PJ; Krilis S, 2011, 'Redox control of â2-glycoprotein I-von Willebrand factor interaction by thioredoxin-1.', Journal of Thrombosis and Haemostasis, vol. 8, pp. 1754 - 1762,

Ioannou Y; Zhang JY; Passam FH; Rahgozar S; Qi JC; Giannakopoulos B; Qi M; Yu P; Yu DM; Hogg PJ; Krilis SA, 2010, 'Naturally occurring free thiols within β2-glycoprotein I in vivo: Nitrosylation, redox modification by endothelial cells, and regulation of oxidative stress-induced cell injury', Blood, vol. 116, pp. 1961 - 1970,

Passam F; Rahgozar S; Qi M; Raftery MJ; Wong J; Tanaka K; Ioannou Y; Zhang JY; Gemmell R; Qi JC; Giannakopoulos B; Hughes WE; Hogg PJ; Krilis S, 2010, 'Beta 2 glycoprotein I is a substrate of thiol oxidoreductases', Blood, vol. 116, pp. 1995 - 1997,

Passam F; Qi JC; Tanaka K; Matthaei K; Krilis S, 2010, 'In vivo modulation of angiogenesis by beta 2 glycoprotein I.', Journal of Autoimmunity, vol. 35, pp. 232 - 240,

Figtree M; Miyakis S; Stenos J; Graves S; Botham S; Ferson MJ; Krilis S, 2010, 'Q fever cholecystitis in an unvaccinated butcher diagnosed by gallbladder plymerase chain reaction', Vector - Borne and Zoonotic Diseases, vol. 10, pp. 421 - 423,

Figtree M; Konecny P; Jennings Z; Goh C; Krilis S; Miyakis S, 2010, 'Risk Stratification and outcome of Cellulitis admitted to hospital', Journal of Infection, vol. 60, pp. 431 - 439,

Figtree MC; Miyakis S; Tanaka K; Martin L; Konecny P; Krilis S, 2009, 'Dapsone hypersensitivity syndrome causing disseminated intravascular coagulation', BMJ Case Reports,

Giannakopoulos B; Krilis S, 2009, 'How I treat the antiphospholipid syndrome', Blood, vol. 114, pp. 2020 - 2030,

Krilis S; Giannakopoulos B; Passam F; Ioannou Y, 2009, 'How we diagnose the antiphospholipid syndrome', Blood, vol. 113, pp. 985 - 994,

Reed J; Giannakopoulos B; Jackson M; Krilis S; Gordon T, 2009, 'Ro 60 functions as a receptor for β2-glycoprotein I on apoptotic cells', Arthritis Care & Research, vol. 60, pp. 860 - 869,

Krilis S; Reed J; Giannakopoulos B; Jackson M; Gordon T, 2009, 'Ro60 Functions as a receptor for B2-glycoprotein I on apoptotic cells', Arthritis Care & Research, vol. 60, pp. 985 - 994

Figtree M; Miyakis S; Jennings Z; Goh C; Konecny P; Krilis S, 2008, 'Factors Influencing Outcome in Cellulitis Admitted to Hospital and the Role of the Infectious Disease Physician', INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, vol. 12, pp. E240 - E240,

Rahgozar S; Giannakopoulos B; Yan X; Wei J; Jian CQ; Gemmell R; Krilis SA, 2008, 'Beta2-glycoprotein I protects thrombin from inhibition by heparin cofactor II: Potentiation of this effect in the presence of anti-β2-glycoprotein I autoantibodies', Arthritis and Rheumatism, vol. 58, pp. 1146 - 1155,

Yu P; Passam F; Yu D; Denyer GS; Krilis S, 2008, 'beta 2-glycoprotein I inhibits vascular endothelial growth factor and basic fibroblast growth factor induced angiogenesis through its amino terminal domain', Journal of Thrombosis and Haemostasis, vol. 6, pp. 1215 - 1223,

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