Select Publications

Journal articles

Dief EM; Tilley RD; Gooding JJ, 2026, 'Electrochemical DNA Biosensors Formed from Self-Assembled Monolayers of Thiolated DNA and Mercaptohexanol: What We Know About This Interface', ACS Sensors, http://dx.doi.org/10.1021/acssensors.6c02162

Seyedzadeh MH; Tolentino MAK; Peres NG; Du EY; Bartlett-Tomasetig F; Javier GMN; Kilian KA; Gaus K; Goyette J; Gooding JJ, 2026, 'Stiff matrix impairs cytotoxic T lymphocyte function at multiple levels', Science Advances, 12, http://dx.doi.org/10.1126/sciadv.ady2299

Kopecky C; Pandzic E; Porazinski S; Gooding JJ; Kilian KA, 2026, 'Matrix Stiffness Directs Stemness Signatures in Breast Cancer', Advanced Healthcare Materials, 15, http://dx.doi.org/10.1002/adhm.71371

Chen X; Li X; Tilley RD; Gooding JJ, 2026, 'The importance of nano–bio interfacial design in the sensing performance of nanoparticle-based affinity biosensors', Chemical Society Reviews, 55, pp. 6182 - 6220, http://dx.doi.org/10.1039/d5cs00823a

Han E; Ramadhan ZR; Pragasam DL; Yao Y; Gooding JJ; Tilley RD, 2026, 'Investigating the Migration of Phosphorus in the Transformation of Branched Cobalt Nanoparticles to Cobalt Phosphide', Crystal Growth and Design, 26, pp. 4313 - 4318, http://dx.doi.org/10.1021/acs.cgd.6c00397

Yang Y; Ma Y; Gooding J, 2026, 'Electrochemical Dye Switching Assisted Spectral Demixing and 3D STORM Imaging', Angewandte Chemie International Edition, 65, pp. e17001, http://dx.doi.org/10.1002/anie.202517001

Yang Y; Ma Y; Gooding J, 2026, 'Electrochemical Dye Switching Assisted Spectral Demixing and 3D STORM Imaging', Angewandte Chemie, 138, http://dx.doi.org/10.1002/ange.202517001

Gooding J, 2026, 'Why Do We Make Bad Electrodes Better When We Could Just Use Good Electrodes?', ACS Sensors, 11, pp. 2880 - 2881, http://dx.doi.org/10.1021/acssensors.6c01387

Yang Y; Ma Y; Tilley RD; Gooding JJ, 2026, 'Electrochemical Control of Fluorescence Emission: From Intensity Modulation to Single Molecule Switching for Applications in Light Microscopy', Accounts of Chemical Research, 59, pp. 751 - 761, http://dx.doi.org/10.1021/acs.accounts.5c00868

Shao S; Hirschbiegel CM; Allan EF; Somerville SV; Gooding JJ; Rotello VM; Xia X, 2026, 'Can nanozymes achieve more than enzymes?', Nature Reviews Materials, http://dx.doi.org/10.1038/s41578-026-00898-3

Ramadhan ZR; Cheong S; Saha S; Li Q; Zheng X; Somerville SV; Poerwoprajitno AR; Kumar PV; Dai L; Gooding JJ; Tilley RD, 2026, 'Phase Boundary Engineering of Co2P-CoP Branched Nanoparticles Enhances Cobalt Oxidation for Oxygen Evolution Electrocatalysis', Advanced Materials, pp. e23118, http://dx.doi.org/10.1002/adma.202523118

Booth MA; Erdal MK; Larson M; Birthisel E; Friedel M; Gonçales VR; Alinezhad A; Morawski F; Li J; Hogan N; Teo S; Wordsworth J; Khanna S; Van Eps J; Boyd S; Dewhirst L; Gerson J; D’Souza D; Yin W; Padmanabhan PT; Batchelor RH; Farnkopf A; Hodges A; Chambers G; Braude M; Kippin TE; Kirkpatrick CMJ; Justin Gooding J; Pianko S; Stocker SL; Plaxco KW, 2026, 'Pilot phase clinical trial of a wearable, electrochemical aptamer-based patch for continuous drug concentration measurement', Nature Biotechnology, http://dx.doi.org/10.1038/s41587-026-03010-w

Cavallo M; Colasuonno F; Somerville SV; Li Q; Ramadhan ZR; Moller AL; Forest C; Thordarson P; Gooding JJ; Tilley RD, 2026, 'Promotion of FFCA formation through the use of highly controlled Ru nanostructures as catalysts for the electrocatalytic oxidation of 5-hydroxymethylfurfural (HMF)', Nanoscale, http://dx.doi.org/10.1039/d6nr02074g

Soda Y; Persson I; Somerville SV; Cheong S; Dissanayake M; Xie Y; Tilley RD; Gooding JJ, 2025, 'A Facile Electrochemical Approach to Synthesizing Stable Single Metal Atom Catalytic Centers and Clusters on N-Doped Carbon for Electrocatalysis', Small, pp. e12625 - e12625, http://dx.doi.org/10.1002/smll.202512625

Jung MS; Poltavets V; Skhinas JN; Tax G; Kamili A; Xie J; Ghamrawi S; Graber P; Mao J; Wong-Erasmus M; Cui L; Kimpton K; Venkat P; Mayoh C; Lin A; Fleuren EDG; Fordham AM; Barger Z; Grady J; Thomas DM; Du EY; Graf NS; Cowley MJ; Gifford AJ; Fletcher JI; Lau LMS; Dolman MEM; Gooding JJ; Kavallaris M; Dolman E; Hearn B, 2025, 'High-throughput 3D engineered paediatric tumour models for precision medicine', Molecular Systems Biology, 21, pp. 1748 - 1777, http://dx.doi.org/10.1038/s44320-025-00152-y

Vu Thanh C; Gooding JJ; Kah M, 2025, 'Learning lessons from nano-medicine to improve the design and performances of nano-agrochemicals', Nature Communications, 16, pp. 2306, http://dx.doi.org/10.1038/s41467-025-57650-8

Batchelor RH; Kaiyum YA; Chao EHP; Tenorio N; Ofori C; Bird SA; Brand HEA; Auckett JE; Karouei MH; Richardson K; Vlcek V; Johnson PE; Gooding JJ; Bonham AJ, 2025, 'The Butterfly Structure of Leucomethylene Blue Results in Weak Binding to Single- or Double-Stranded DNA', Journal of Physical Chemistry B, 129, pp. 12110 - 12119, http://dx.doi.org/10.1021/acs.jpcb.5c05704

Hagness DE; Ishtiaq S; Somerville SV; Yang Y; Ma Y; Tilley RD; Gooding JJ, 2025, 'Electrochemically Stimulated Autofluorescence of Indium Tin Oxide Surface: The Implications for Fluorescence Microscopy', ACS Electrochemistry, 1, pp. 2690 - 2699, http://dx.doi.org/10.1021/acselectrochem.5c00242

Ramadhan ZR; Poerwoprajitno AR; Cheong S; Gooding JJ; Tilley R, 2025, 'Size-Controlled Cobalt Nanoplates and Their Impact on Oxygen Evolution Catalysis', Chemistry A European Journal, 31, pp. e02484 - e02484, http://dx.doi.org/10.1002/chem.202502484

Li Q; Cheong S; Poerwoprajitno AR; Xiang S; Frenkel AI; Yang Y; Bedford NM; Umer S; Lessio M; Ohnishi I; Ramadhan ZR; Huber DL; Dai L; Schuhmann W; Gooding JJ; Tilley RD, 2025, 'How the Arrangement of Platinum Atoms on Ruthenium Nanoparticles Improves Hydrogen Evolution Activity', Advanced Materials, 37, pp. e09610, http://dx.doi.org/10.1002/adma.202509610

Romanazzo S; Tian P; Jalandhra GK; Doshi RB; Gooding JJ; Kilian KA, 2025, 'A biofabricated 3D cancer-stroma tumor microenvironment model', Biofabrication, 17, pp. 045019, http://dx.doi.org/10.1088/1758-5090/ae0a82

Abdibastami A; Poerwoprajitno AR; Ramadhan ZR; Shanehsazzadeh S; Bongers A; Forest C; Gooding JJ; Tilley RD, 2025, 'How octopod Mn–Fe oxide nanoparticle tracers minimize relaxation time and enhance MPI resolution', Nanoscale, 17, pp. 21463 - 21467, http://dx.doi.org/10.1039/d5nr02780b

Soliman BG; Tian P; Cui J; Kilian KA; Gooding JJ, 2025, 'Interfacial Stress Regulates Plasticity and Drug Resistance at the Breast Cancer-Host Interface', Advanced Science, 12, pp. e09361, http://dx.doi.org/10.1002/advs.202509361

Dauphin-Ducharme P; Dief EM; Corcoran N; Gooding JJ, 2025, 'Reading the Pulse of Electrochemical Aptamer-Based Biosensors: Implications of Different Interrogation Methods', ACS Electrochemistry, 1, pp. 2264 - 2275, http://dx.doi.org/10.1021/acselectrochem.5c00316

Somerville SV; Benedetti TM; Ramadhan ZR; Yao Y; Tilley RD; Gooding JJ, 2025, 'A nanozyme that can go beyond an enzyme: the selective detection of two species in the same whole blood sample', Chemical Science, 16, pp. 16867 - 16875, http://dx.doi.org/10.1039/d5sc04268b

Oluigbo CJ; Poerwoprajitno AR; Xie Y; Somerville SV; Persson I; Ramadhan ZR; Cheong S; Dai L; Huber DL; Gooding JJ; Tilley RD, 2025, 'Controlling the Ru Island Decoration on Ni Nanoparticles to Tune the Activity for 5-Hydroxylmethylfurfural (HMF) Oxidation', Chemistry of Materials, 37, pp. 6090 - 6095, http://dx.doi.org/10.1021/acs.chemmater.5c01781

Li Q; Cheong S; Ishtiaq S; Somerville SV; Cavallo M; Watt J; Gooding JJ; Tilley RD, 2025, 'Effect of Iron Oxidation on the Activity of Platinum-Decorated Iron Nanoparticles for the Hydrogen Evolution Reaction', Crystal Growth and Design, 25, pp. 6796 - 6802, http://dx.doi.org/10.1021/acs.cgd.5c00742

Yang Y; Ma Y; Tilley RD; Gooding JJ, 2025, 'Electrochemically controlled switching of dyes for enhanced superresolution optical fluctuation imaging (EC-SOFI)', Proceedings of the National Academy of Sciences of the United States of America, 122, pp. e2425390122, http://dx.doi.org/10.1073/pnas.2425390122

Yang Y; Ma Y; Macmillan A; Tilley R; Gooding JJ, 2025, 'Electrochemical fluorescence modulation enables simultaneous multicolour imaging', Nature Photonics, 19, pp. 718 - 724, http://dx.doi.org/10.1038/s41566-025-01672-7

Du EY; Duong HTK; Tolentino MAK; Houng JL; Suwannakot P; Tjandra KC; Nguyen DHT; Tilley RD; Justin Gooding J; Gooding J, 2025, 'Ionically crosslinked biohybrid gelatin-based hydrogels for 3D cell culture', Macromolecular Research, 33, pp. 921 - 931, http://dx.doi.org/10.1007/s13233-025-00380-z

Batchelor RH; Dief EM; Bonham AJ; Gooding JJ, 2025, 'A Review of Methylene Blue’s Interactions with DNA and Their Relevance for DNA-Based Sensors', ACS Sensors, 10, pp. 3854 - 3877, http://dx.doi.org/10.1021/acssensors.5c00336

Tolentino MAK; Du EY; Silvani G; Pandzic E; Kilian KA; Gooding JJ, 2025, 'Decoding Hydrogel Porosity: Advancing the Structural Analysis of Hydrogels for Biomedical Applications', Advanced Healthcare Materials, 14, pp. 2500658 - 2500658, http://dx.doi.org/10.1002/adhm.202500658

Dief EM; Tang W; Carroll LR; Breton T; Gooding JJ, 2025, 'Preparation of electrochemical aptamer-based sensors: a direct aryl diazonium grafting approach', Chemical Communications, 61, pp. 7648 - 7651, http://dx.doi.org/10.1039/d5cc00857c

Hu C; Dief EM; Soliman BG; Romanazzo S; Rana S; Kilian KA; Tilley RD; Gooding JJ, 2025, 'Direct detection of microRNA in liquid biopsies from single cancer spheroids', Chemical Science, 16, pp. 8970 - 8978, http://dx.doi.org/10.1039/d5sc01036e

Xiao S; Xie Y; Poerwoprajitno AR; Gloag L; Li Q; Cheong S; Ramadhan ZR; Persson I; Soda Y; Huber DL; Dai L; Gooding JJ; Tilley RD, 2025, 'Formation of open ruthenium branched structures with highly exposed active sites for oxygen evolution reaction electrocatalysis', Chemical Science, 16, pp. 9284 - 9289, http://dx.doi.org/10.1039/d5sc01861g

Hagness DE; Yang Y; Ma Y; Ishtiaq S; Fan S; Tilley RD; Gooding JJ, 2025, 'An investigative study of electrochemical induced fluorescence for fluorophores', Chemical Science, 16, pp. 8959 - 8969, http://dx.doi.org/10.1039/d5sc01265a

Ikram F; Cheong S; Persson I; Ramadhan ZR; Poerwoprajitno AR; Gooding JJ; Tilley RD, 2025, 'Iridium Nanocrystals Enriched with Defects and Atomic Steps to Enhance Oxygen Evolution Reaction Performance', Journal of the American Chemical Society, 147, pp. 10784 - 10790, http://dx.doi.org/10.1021/jacs.5c02151

Doan THP; Fried JP; Tang W; Hagness DE; Wu Y; Tilley RD; Gooding JJ, 2025, 'Optical Nanopore Blockade Sensors for Multiplexed Detection of Proteins', Nano Letters, 25, pp. 3233 - 3239, http://dx.doi.org/10.1021/acs.nanolett.4c05934

Duong HTK; Poerwoprajitno AR; Bongers A; Shanehsazzadeh S; Abdibastami A; Sulway S; Rich A; Gooding JJ; Tilley RD, 2025, 'Understanding the Influence of Gd Deposition on the MPI and MRI Performance of Fe3O4 Nanoparticles for Multimodal Imaging Applications', Journal of Physical Chemistry B, 129, pp. 1774 - 1783, http://dx.doi.org/10.1021/acs.jpcb.4c08077

Dissanayake M; Somerville SV; Soda Y; Yao Y; Duong HTK; Tilley RD; Gooding JJ, 2025, 'An Array of Glucose Nanozymes That Can Selectively Detect Glucose in Whole Blood', ACS Sensors, 10, pp. 545 - 552, http://dx.doi.org/10.1021/acssensors.4c03106

Cavallo M; Ramadhan ZR; Somerville SV; Han E; Webster RF; Cheong S; Baldino S; Lessio M; Gooding JJ; Tilley RD, 2025, 'Enhancing the Electrocatalytic Oxidation of 5-Hydroxymethylfurfural (HMF) via Metallic Cobalt in Au-Co Nanoparticles', Journal of Physical Chemistry C, 129, pp. 1243 - 1251, http://dx.doi.org/10.1021/acs.jpcc.4c07907

Han E; Ramadhan ZR; Nichol A; Yao Y; Cheong S; Gooding JJ; Tilley RD, 2025, 'Growth Mechanism of Seed-Mediated, Hexagonal Prism Copper Phosphide Nanoparticles', Crystal Growth and Design, 25, pp. 136 - 142, http://dx.doi.org/10.1021/acs.cgd.4c01440

Somerville SV; Dissanayake M; Soda Y; Benedetti TM; Tilley RD; Gooding JJ, 2025, 'pH-Dependant Electrochemical Oxidation of Small Molecules on Glassy Carbon, Platinum and Gold', Electroanalysis, 37, http://dx.doi.org/10.1002/elan.12013

Tolentino M; Seyedzadeh M; Peres N; Du E; Zhu L; Gaus K; Goyette J; Gooding J, 2024, 'Polyethylene Glycol-Based Hydrogel as a 3D Extracellular Matrix Mimic for Cytotoxic T Lymphocytes', Journal of Biomedical Materials Research - Part A, http://dx.doi.org/10.1002/jbm.a.37811

Soliman BG; Nguyen AK; Gooding JJ; Kilian KA, 2024, 'Advancing Synthetic Hydrogels through Nature-Inspired Materials Chemistry', Advanced Materials, 36, pp. e2404235 - e2404235, http://dx.doi.org/10.1002/adma.202404235

Jia C; Sun Q; Liu R; Mao G; Maschmeyer T; Gooding JJ; Zhang T; Dai L; Zhao C, 2024, 'Challenges and Opportunities for Single-Atom Electrocatalysts: From Lab-Scale Research to Potential Industry-Level Applications', Advanced Materials, 36, pp. e2404659, http://dx.doi.org/10.1002/adma.202404659

Jamali SS; Wu Y; Homborg AM; Lemay SG; Gooding JJ, 2024, 'Interpretation of stochastic electrochemical data', Current Opinion in Electrochemistry, 46, pp. 101505, http://dx.doi.org/10.1016/j.coelec.2024.101505

Benedetti TM; Somerville SV; Wordsworth J; Yamamoto Y; Schuhmann W; Tilley RD; Gooding JJ, 2024, 'An Artificial Enzyme: How Nanoconfinement Allows the Selective Electrochemical Detection of Glucose Directly in Whole Blood', Advanced Functional Materials, 34, http://dx.doi.org/10.1002/adfm.202400322

Yang Y; Ma Y; Gooding JJ, 2024, 'The electrochemical modulation of single molecule fluorescence', Faraday Discussions, 257, pp. 333 - 343, http://dx.doi.org/10.1039/d4fd00111g

Yang Y; Ma Y; Berengut JF; Lee LK; Tilley RD; Gaus K; Gooding JJ, 2024, 'Electrochemically controlled blinking of fluorophores for quantitative STORM imaging', Nature Photonics, 18, pp. 713 - 720, http://dx.doi.org/10.1038/s41566-024-01431-0


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