By Scientia Professor Matthew Colm Kiernan

Journal articles

Feldman EL; Sattler R; Kiernan MC; Goutman SA; Chiò A; Al-Chalabi A, 2025, 'Transforming amyotrophic lateral sclerosis into a liveable disease', Lancet Neurology, 24, pp. 100 - 101, http://dx.doi.org/10.1016/S1474-4422(24)00523-4

Koren TJ; Kiernan MC, 2025, 'Post-infectious acute cerebellar ataxia in a young adult', BMJ Case Reports, 18, http://dx.doi.org/10.1136/bcr-2024-262043

Kiernan MC; Davis SM, 2025, 'Stroke is not optional for neurologists', Practical Neurology, 25, pp. 2 - 3, http://dx.doi.org/10.1136/pn-2024-004230

Ziser L; van Eijk RPA; Kiernan MC; McRae A; Henderson RD; Schultz D; Needham M; Mathers S; McCombe P; Talman P; Vucic S, 2025, 'Amyotrophic lateral sclerosis established as a multistep process across phenotypes', European Journal of Neurology, 32, http://dx.doi.org/10.1111/ene.16532

Tse NY; Caga J; Ahmed RM; Mazumder S; Nguyen C; Huynh W; Karjalainen A; Timmins HC; Ramsey E; Talbot DL; Halliday GM; Kiernan MC; Devenney EM, 2025, 'Behavioral subtypes impact prognosis and survival in amyotrophic lateral sclerosis: a clustering-based approach', Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 26, pp. 729 - 738, http://dx.doi.org/10.1080/21678421.2025.2522402

O'Keefe E; Kiernan M; Huynh W, 2025, 'Cerebrotendinous xanthomatosis: A complex interplay between a clinically and genetically heterogeneous condition', European Journal of Neurology, 32, http://dx.doi.org/10.1111/ene.70006

Mazumder S; Carroll AS; Timmins HC; Kiernan MC; Mahoney CJ, 2025, 'Impact of the COVID-19 pandemic on the mental and physical wellbeing of patients with motor neuron disease and other neuromuscular disease', Frontiers in Neurology, 16, http://dx.doi.org/10.3389/fneur.2025.1514983

Scirocco E; Allen MD; Giacomelli E; Ajroud-Driss S; Andrews J; Banack S; Bede P; Benatar M; Cheung K; Corcia P; de Carvalho M; Elman L; Fink JK; Genge A; Hardiman O; Harms M; Heitzman D; Jang G; Kano O; Kiernan MC; Lee I; Ludolph A; Mehta P; Ozdinler H; Rezania K; Schito P; Sherman AV; Silani V; Sorenson E; Turner MR; Van Den Berg L; Mitsumoto H; Paganoni S, 2025, 'Toward therapeutic trials in primary lateral sclerosis', Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 26, pp. 623 - 630, http://dx.doi.org/10.1080/21678421.2025.2527123

Pavey N; Menon P; Peterchev A; Kiernan M; Vucic S, 2025, 'Abnormalities of cortical stimulation strength-duration time constant in amyotrophic lateral sclerosis', Brain Stimulation, 18, pp. 311 - 312, http://dx.doi.org/10.1016/j.brs.2024.12.293

Kiernan M, 2025, 'Clinical trials – ALS diagnosis and stratification', Journal of the Neurological Sciences, 480, pp. 123781, http://dx.doi.org/10.1016/j.jns.2025.123781

Joda M; Li T; Timmins HC; Goldstein D; Kiernan MC; Park SB, 2025, 'Identification of axonal degeneration in paclitaxel-treated patients utilising neurophysiological and blood based biomarkers', Clinical Neurophysiology, 176, pp. 2110928 - 2110928, http://dx.doi.org/10.1016/j.clinph.2025.2110928

Lam W; Park S; Carroll A; Kiernan M; Li T; Lin CS-Y, 2025, 'Quantifying the response to immunoglobulin therapy in Chronic Inflammatory Demyelinating Polyneuropathy', Clinical Neurophysiology, 176, pp. 2110923 - 2110923, http://dx.doi.org/10.1016/j.clinph.2025.2110923

Li T; Timmins HC; Horvath LG; Harrison M; Grimison P; Friedlander M; Marx G; Boyle F; Wyld D; Henderson R; King T; Baron-Hay S; Kiernan MC; Barnes EH; Goldstein D; Park SB, 2025, 'Risk factors for dose-limiting, chronic and severe chemotherapy-induced peripheral neuropathy', Clinical Neurophysiology, 176, pp. 2110921, http://dx.doi.org/10.1016/j.clinph.2025.2110921

Tu S; Li T; Carroll AS; Mahoney CJ; Huynh W; Park SB; Henderson R; Vucic S; Kiernan MC; Lin CSY, 2024, 'Central neurodegeneration in Kennedy’s disease accompanies peripheral motor dysfunction', Scientific Reports, 14, http://dx.doi.org/10.1038/s41598-024-69393-5

J M Dick T; Tucker K; Hug F; Besomi M; van Dieën JH; Enoka RM; Besier T; Carson RG; Clancy EA; Disselhorst-Klug C; Falla D; Farina D; Gandevia S; Holobar A; Kiernan MC; Lowery M; McGill K; Merletti R; Perreault E; Rothwell JC; Søgaard K; Wrigley T; Hodges PW, 2024, 'Consensus for experimental design in electromyography (CEDE) project: Application of EMG to estimate muscle force', Journal of Electromyography and Kinesiology, 79, pp. 102910, http://dx.doi.org/10.1016/j.jelekin.2024.102910

Timmins HC; Thompson AE; Kiernan MC, 2024, 'Diagnostic criteria for amyotrophic lateral sclerosis', Current Opinion in Neurology, 37, pp. 570 - 576, http://dx.doi.org/10.1097/WCO.0000000000001302

Kiernan MC; Kaji R, 2024, 'Emerging concepts and therapies for amyotrophic lateral sclerosis', Current Opinion in Neurology, 37, pp. 558 - 559, http://dx.doi.org/10.1097/WCO.0000000000001308

Tu S; Vucic S; Kiernan MC, 2024, 'Pathological insights derived from neuroimaging in amyotrophic lateral sclerosis: Emerging clinical applications', Current Opinion in Neurology, 37, pp. 577 - 584, http://dx.doi.org/10.1097/WCO.0000000000001295

Devenney EM; Anh N Nguyen Q; Tse NY; Kiernan MC; Tan RH, 2024, 'A scoping review of the unique landscape and challenges associated with dementia in the Western Pacific region', Lancet Regional Health Western Pacific, 50, http://dx.doi.org/10.1016/j.lanwpc.2024.101192

Timmins HC; Mok VCT; Kim SH; Shahrizaila N; Sung JY; Sobue G; Agustini S; Ward S; Anstey KJ; Talbot DL; Mazumder S; Tu S; Tan RH; Shin-Yi Lin C; O'Callaghan C; Michaelian JC; Jeon YH; Foxe D; Naismith SL; Piguet O; Ahmed R; Devenney E; Park SB; Kiernan MC, 2024, 'Regional health priorities for dementia: a roadmap for the Western Pacific', Lancet Regional Health Western Pacific, 50, pp. 101179, http://dx.doi.org/10.1016/j.lanwpc.2024.101179

Clarke AJ; Brodtmann A; Irish M; Mowszowski L; Radford K; Naismith SL; Mok VCT; Kiernan MC; Halliday GM; Ahmed RM, 2024, 'Risk factors for the neurodegenerative dementias in the Western Pacific region', Lancet Regional Health Western Pacific, 50, http://dx.doi.org/10.1016/j.lanwpc.2024.101051

Reynolds M; Tan I; Nguyen K; Merheb V; Lee FXZ; Trewin BP; Lerch M; Shah S; Wolfe N; Buzzard K; Lechner-Scott J; Fabis-Pedrini M; Fok A; John N; Kneebone C; Yiannikas C; Brown DA; Kermode AG; Reddel S; Dale RC; Brilot F; Ramanathan S; Adam R; Andersen J; Andrews I; Antony J; Aouad P; Badve M; Barnett MH; Barton J; Beadnall H; Blum S; Boggild M; Broadley S; Burrow J; Butzkueven H; Bye A; Cairns A; Calvert S; Chan F; Chelakkadan S; Chu M; Clark DR; Cotter I; Dela Cruz F; Fabis-Pedrini MJ; Field D; Fraser CL; Fung VSC; Garber J; Geara S; Gill D; Gupta S; Hardy TA; Hawke S; Henderson APD; Jeyakumar N; Jones DL; Jones HF; Kalincik T; Kiernan M; Kilpatrick T; Kornberg AJ; Lawlor M; Lechner-Scott J; Leventer RJ; Li V; Ling S; Liyanage G; Lopez JA; Ma KKM; Malone S; Marriot MP; McCombe P; McDougall A; Menezes MP; Miteff C; Monif M; Musuwadi Subramanian G; Nguyen AL; O'Grady G; Ouvrier R; Paine M; Parratt J; Pillai S; Prosser J; Qiu J, 2024, 'The clinical relevance of MOG antibody testing in cerebrospinal fluid', Annals of Clinical and Translational Neurology, 11, pp. 2514 - 2519, http://dx.doi.org/10.1002/acn3.52163

Li T; Timmins HC; Mahfouz FM; Trinh T; Mizrahi D; Horvath LG; Harrison M; Grimison P; Friedlander M; Marx G; Boyle F; Wyld D; Henderson R; King T; Baron-Hay S; Kiernan MC; Rutherford C; Goldstein D; Park SB, 2024, 'Validity of Patient-Reported Outcome Measures in Evaluating Nerve Damage Following Chemotherapy', JAMA Network Open, 7, pp. e2424139, http://dx.doi.org/10.1001/jamanetworkopen.2024.24139

Rahiman K J, 2024, 'Chemotherapy-Induced Neurotoxicity', International Journal of Science and Research (IJSR), 13, pp. 1250 - 1254, http://dx.doi.org/10.21275/sr24820170848

Pavey NA; Menon P; Peterchev AV; Kiernan MC; Vucic S, 2024, 'Abnormalities of cortical stimulation strength-duration time constant in amyotrophic lateral sclerosis', Clinical Neurophysiology, 164, pp. 161 - 167, http://dx.doi.org/10.1016/j.clinph.2024.05.014

Pavey N; Hannaford A; Van Den Bos M; Kiernan MC; Menon P; Vucic S, 2024, 'Distinct neuronal circuits mediate cortical hyperexcitability in amyotrophic lateral sclerosis', Brain, 147, pp. 2344 - 2356, http://dx.doi.org/10.1093/brain/awae049

Gray E; Menadue C; Piper A; Wong K; Yee B; Kiernan M, 2024, 'Hypercapnia is not excluded by normoxia in neuromuscular disease patients: implications for oximetry', Erj Open Research, 10, http://dx.doi.org/10.1183/23120541.00927-2023

Dharmadasa T; Pavey N; Tu S; Menon P; Huynh W; Mahoney CJ; Timmins HC; Higashihara M; van den Bos M; Shibuya K; Kuwabara S; Grosskreutz J; Kiernan MC; Vucic S, 2024, 'Novel approaches to assessing upper motor neuron dysfunction in motor neuron disease/amyotrophic lateral sclerosis: IFCN handbook chapter', Clinical Neurophysiology, 163, pp. 68 - 89, http://dx.doi.org/10.1016/j.clinph.2024.04.010

Higashihara M; Pavey N; Menon P; van den Bos M; Shibuya K; Kuwabara S; Kiernan MC; Koinuma M; Vucic S, 2024, 'Reduction in short interval intracortical inhibition from the early stage reflects the pathophysiology in amyotrophic lateral sclerosis: A meta-analysis study', European Journal of Neurology, 31, http://dx.doi.org/10.1111/ene.16281

Taş G; Westerdijk T; Postma E; van Rheenen W; Bakker MK; van Eijk KR; Kooyman M; Al Khleifat A; Iacoangeli A; Ticozzi N; Cooper-Knock J; Gromicho M; Chandran S; Morrison KE; Shaw PJ; Hardy J; Sendtner M; Meyer T; Başak N; Fogh I; Chiò A; Calvo A; Pupillo E; Logroscino G; Gotkine M; Vourc’h P; Corcia P; Couratier P; Millecamps S; Salachas F; Pardina JSM; Rojas-García R; Dion P; Ross JP; Ludolph AC; Weishaupt JH; Freischmidt A; Bensimon G; Tittmann L; Lieb W; Franke A; Ripke S; Whiteman DC; Olsen CM; Uitterlinden AG; Hofman A; Amouyel P; Traynor B; Singleton AB; Neto MM; Cauchi RJ; Ophoff RA; van Deerlin VM; Grosskreutz J; Graff C; Brylev L; Rogelj B; Koritnik B; Zidar J; Stević Z; Drory V; Povedano M; Blair IP; Kiernan MC; Nicholson GA; Henders AK; de Carvalho M; Pinto S; Petri S; Weber M; Rouleau GA; Silani V; Glass J; Brown RH; Landers JE; Shaw CE; Andersen PM; Garton FC; McRae AF; McLaughlin RL; Hardiman O; Kenna KP; Wray NR; Al-Chalabi A; Van Damme P; van den Berg LH; Veldink JH; Veldink JH; Schönhuth A; Balvert M, 2024, 'Computing linkage disequilibrium aware genome embeddings using autoencoders', Bioinformatics, 40, pp. btae326, http://dx.doi.org/10.1093/bioinformatics/btae326

Besomi M; Devecchi V; Falla D; McGill K; Kiernan MC; Merletti R; van Dieën JH; Tucker K; Clancy EA; Søgaard K; Hug F; Carson RG; Perreault E; Gandevia S; Besier T; Rothwell JC; Enoka RM; Holobar A; Disselhorst-Klug C; Wrigley T; Lowery M; Farina D; Hodges PW, 2024, 'Consensus for experimental design in electromyography (CEDE) project: Checklist for reporting and critically appraising studies using EMG (CEDE-Check)', Journal of Electromyography and Kinesiology, 76, http://dx.doi.org/10.1016/j.jelekin.2024.102874

Li T; Timmins HC; Mahfouz FM; Mizrahi D; Horvath L; Harrison ML; Grimison PS; Friedlander M; Marx GM; Boyle FM; Wyld D; Henderson R; King T; Baron-Hay SE; Kiernan MC; Rutherford C; Goldstein D; Park SB, 2024, 'Identifying optimized assessment of nerve damage during chemotherapy.', Journal of Clinical Oncology, 42, pp. 12016 - 12016, http://dx.doi.org/10.1200/jco.2024.42.16_suppl.12016

Li T; Trinh T; Bosco A; Kiernan MC; Goldstein D; Park SB, 2024, 'Characterising vincristine-induced peripheral neuropathy in adults: symptom development and long-term persistent outcomes', Supportive Care in Cancer, 32, http://dx.doi.org/10.1007/s00520-024-08484-5

Eisen A; Pioro EP; Goutman SA; Kiernan MC, 2024, 'Nanoplastics and Neurodegeneration in ALS', Brain Sciences, 14, http://dx.doi.org/10.3390/brainsci14050471

Silsby M; Yiannikas C; Fois AF; Kennerson ML; Kiernan MC; Fung VSC; Vucic S, 2024, 'Upper and lower limb tremor in Charcot–Marie–Tooth neuropathy type 1A and the implications for standing balance', Journal of Neurology, 271, pp. 1776 - 1786, http://dx.doi.org/10.1007/s00415-023-12124-z

Carroll AS; Park SB; Lin CSY; Taylor MS; Kwok F; Simon NG; Reilly MM; Kiernan MC; Vucic S, 2024, 'Axonal excitability as an early biomarker of nerve involvement in hereditary transthyretin amyloidosis', Clinical Neurophysiology, 159, pp. 81 - 95, http://dx.doi.org/10.1016/j.clinph.2024.01.006

Eisen A; Nedergaard M; Gray E; Kiernan MC, 2024, 'The glymphatic system and Amyotrophic lateral sclerosis', Progress in Neurobiology, 234, http://dx.doi.org/10.1016/j.pneurobio.2024.102571

Silsby M; Yiannikas C; Fois AF; Kiernan MC; Fung VSC; Vucic S, 2024, 'Upper and lower limb tremor in inflammatory neuropathies', Clinical Neurophysiology, 158, pp. 69 - 78, http://dx.doi.org/10.1016/j.clinph.2023.12.005

Devenney EM; Tse NY; O’Callaghan C; Kumfor F; Ahmed RM; Caga J; Hazelton JL; Carrick J; Halliday GM; Piguet O; Kiernan MC; Hodges JR, 2024, 'An attentional and working memory theory of hallucination vulnerability in frontotemporal dementia', Brain Communications, 6, http://dx.doi.org/10.1093/braincomms/fcae123

Carroll AS; Razvi Y; O’Donnell L; Veleva E; Heslegrave A; Zetterberg H; Vucic S; Kiernan MC; Rossor AM; Gillmore JD; Reilly MM, 2024, 'Serum neurofilament light chain in hereditary transthyretin amyloidosis: validation in real-life practice', Amyloid, 31, pp. 95 - 104, http://dx.doi.org/10.1080/13506129.2024.2313218

Henden L; Fearnley LG; Southwood D; Smith A; Rowe DB; Kiernan MC; Pamphlett R; Bahlo M; Blair IP; Williams KL, 2024, 'Short tandem repeat expansions in LRP12 are absent in cohorts of familial and sporadic amyotrophic lateral sclerosis patients of European ancestry', Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 25, pp. 644 - 647, http://dx.doi.org/10.1080/21678421.2024.2348636

Wippich A; Howatson G; Allen-Baker G; Farrell D; Kiernan M; Scott-Bell A, 2024, 'Eye Movement Desensitization Reprocessing as a Treatment for PTSD in Conflict-Affected Areas', Psychological Trauma Theory Research Practice and Policy, 16, pp. s561 - s567, http://dx.doi.org/10.1037/tra0001430

Dharmadasa T; Pavey N; Tu S; Menon P; Huynh W; Mahoney CJ; Timmins HC; Higashihara M; Bos MVD; Shibuya K; Kuwabara S; Grosskreutz J; Kiernan MC; Vucic S, 2024, 'Novel approaches to assessing upper motor neuron dysfunction in motor neuron disease/amyotrophic lateral sclerosis: IFCN handbook chapter', CLINICAL NEUROPHYSIOLOGY, 163, pp. 68 - 89, http://dx.doi.org/10.1016/j.clinph.2024.04.010

Tan RH; McCann H; Shepherd CE; Pinkerton M; Mazumder S; Devenney EM; Adler GL; Rowe DB; Kril J; Halliday GM; Kiernan MC, 2023, 'Heterogeneity of cortical pTDP-43 inclusion morphologies in amyotrophic lateral sclerosis', Acta Neuropathologica Communications, 11, http://dx.doi.org/10.1186/s40478-023-01670-2

Kiernan MC; Halliday GM; Rowe DB; Tan RH, 2023, 'The importance of patient-centred drug development for amyotrophic lateral sclerosis', Neuropathology and Applied Neurobiology, 49, http://dx.doi.org/10.1111/nan.12944

Pavey N; Hannaford A; Higashihara M; van den Bos M; Kiernan MC; Menon P; Vucic S, 2023, 'Utility of split hand index with different motor unit number estimation techniques in ALS', Clinical Neurophysiology, 156, pp. 175 - 182, http://dx.doi.org/10.1016/j.clinph.2023.09.018

Kiernan MC; Farrar MA, 2023, 'Emerging role for sphingolipids in the genetics of amyotrophic lateral sclerosis', Journal of Neurology Neurosurgery and Psychiatry, 95, pp. 101 - 102, http://dx.doi.org/10.1136/jnnp-2023-332719

Li T; Kandula T; Cohn RJ; Kiernan MC; Park SB; Farrar MA, 2023, 'Prospective assessment of vincristine-induced peripheral neuropathy in paediatric acute lymphoblastic leukemia', Clinical Neurophysiology, 154, pp. 157 - 168, http://dx.doi.org/10.1016/j.clinph.2023.08.002

Silsby M; Yiannikas C; Fois AF; Ng K; Kiernan MC; Fung VSC; Vucic S, 2023, 'Imbalance and lower limb tremor in chronic inflammatory demyelinating polyradiculoneuropathy', Journal of the Peripheral Nervous System, 28, pp. 415 - 424, http://dx.doi.org/10.1111/jns.12574

Farrar MA; Kiernan MC; Kariyawasam DS, 2023, 'Presymptomatic spinal muscular atrophy: a cautionary approach to the proposed new terminology', Brain, 146, pp. E65 - E66, http://dx.doi.org/10.1093/brain/awad061

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