By Scientia Professor Matthew Colm Kiernan

Journal articles

Cade BE; Hassan SM; Dashti HS; Kiernan M; Pavlova MK; Redline S; Karlson EW, 2022, 'Sleep apnea phenotyping and relationship to disease in a large clinical biobank.', JAMIA Open, 5, pp. ooab117, http://dx.doi.org/10.1093/jamiaopen/ooab117

Lin C; Li T; Tu S; Park S; Vucic S; Kiernan M, 2022, 'TH-265. Evidence of sensory and fine motor dysfunction in peripheral and central nervous systems in Kennedy’s disease (KD)', Clinical Neurophysiology, 141, pp. S171 - S171, http://dx.doi.org/10.1016/j.clinph.2022.07.451

Kiernan M; Renshaw H; Mitry D; Bremner F, 2022, 'Two ophthalmic presentations of chronic myeloid leukaemia.', EJHaem, 3, pp. 1064 - 1065, http://dx.doi.org/10.1002/jha2.461

Caga J; Tu S; Dharmadasa T; Tse NY; Zoing MC; Huynh W; Mahoney C; Ahmed RM; Kiernan MC, 2021, 'Apathy is associated with parietal cortical-subcortical dysfunction in ALS', Cortex, 145, pp. 341 - 349, http://dx.doi.org/10.1016/j.cortex.2021.02.029

van Rheenen W; van der Spek RAA; Bakker MK; van Vugt JJFA; Hop PJ; Zwamborn RAJ; de Klein N; Westra HJ; Bakker OB; Deelen P; Shireby G; Hannon E; Moisse M; Baird D; Restuadi R; Dolzhenko E; Dekker AM; Gawor K; Westeneng HJ; Tazelaar GHP; van Eijk KR; Kooyman M; Byrne RP; Doherty M; Heverin M; Al Khleifat A; Iacoangeli A; Shatunov A; Ticozzi N; Cooper-Knock J; Smith BN; Gromicho M; Chandran S; Pal S; Morrison KE; Shaw PJ; Hardy J; Orrell RW; Sendtner M; Meyer T; Başak N; van der Kooi AJ; Ratti A; Fogh I; Gellera C; Lauria G; Corti S; Cereda C; Sproviero D; D’Alfonso S; Sorarù G; Siciliano G; Filosto M; Padovani A; Chiò A; Calvo A; Moglia C; Brunetti M; Canosa A; Grassano M; Beghi E; Pupillo E; Logroscino G; Nefussy B; Osmanovic A; Nordin A; Lerner Y; Zabari M; Gotkine M; Baloh RH; Bell S; Vourc’h P; Corcia P; Couratier P; Millecamps S; Meininger V; Salachas F; Mora Pardina JS; Assialioui A; Rojas-García R; Dion PA; Ross JP; Ludolph AC; Weishaupt JH; Brenner D; Freischmidt A; Bensimon G; Brice A; Durr A; Payan CAM; Saker-Delye S; Wood NW; Topp S; Rademakers R; Tittmann L; Lieb W; Franke A; Ripke S; Braun A; Kraft J, 2021, 'Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology', Nature Genetics, 53, pp. 1636 - 1648, http://dx.doi.org/10.1038/s41588-021-00973-1

Gabery S; Ahmed RM; Caga J; Kiernan MC; Halliday GM; Petersén Å, 2021, 'Loss of the metabolism and sleep regulating neuronal populations expressing orexin and oxytocin in the hypothalamus in amyotrophic lateral sclerosis', Neuropathology and Applied Neurobiology, 47, pp. 979 - 989, http://dx.doi.org/10.1111/nan.12709

Agarwal S; Highton-Williamson E; Caga J; Howells J; Dharmadasa T; Matamala JM; Ma Y; Shibuya K; Hodges JR; Ahmed RM; Vucic S; Kiernan MC, 2021, 'Motor cortical excitability predicts cognitive phenotypes in amyotrophic lateral sclerosis', Scientific Reports, 11, http://dx.doi.org/10.1038/s41598-021-81612-x

Phan K; He Y; Fu YH; Dzamko N; Bhatia S; Gold J; Rowe D; Ke YD; Ittner LM; Hodges JR; Piguet O; Kiernan MC; Halliday GM; Kim WS, 2021, 'Pathological manifestation of human endogenous retrovirus K in frontotemporal dementia', Communications Medicine, 1, http://dx.doi.org/10.1038/s43856-021-00060-w

Kiernan MC, 2021, 'The end of the affair?', Journal of Neurology, Neurosurgery and Psychiatry, 92, pp. 1249 - 1250, http://dx.doi.org/10.1136/jnnp-2021-328176

Devenney EM; McErlean K; Tse NY; Caga J; Dharmadasa T; Huynh W; Mahoney CJ; Zoing M; Mazumder S; Dobson-Stone C; Kwok JB; Halliday GM; Hodges JR; Piguet O; Ahmed RM; Kiernan MC, 2021, 'Factors That Influence Non-Motor Impairment Across the ALS-FTD Spectrum: Impact of Phenotype, Sex, Age, Onset and Disease Stage', Frontiers in Neurology, 12, http://dx.doi.org/10.3389/fneur.2021.743688

Vucic S; Ferguson TA; Cummings C; Hotchkin MT; Genge A; Glanzman R; Roet KCD; Cudkowicz M; Kiernan MC, 2021, 'Gold Coast diagnostic criteria: Implications for ALS diagnosis and clinical trial enrollment', Muscle and Nerve, 64, pp. 532 - 537, http://dx.doi.org/10.1002/mus.27392

Sommer C; Carroll AS; Koike H; Katsuno M; Ort N; Sobue G; Vucic S; Spies JM; Doppler K; Kiernan MC, 2021, 'Nerve biopsy in acquired neuropathies', Journal of the Peripheral Nervous System, 26, pp. S21 - S41, http://dx.doi.org/10.1111/jns.12464

Li T; Mizrahi D; Goldstein D; Kiernan MC; Park SB, 2021, 'Chemotherapy and peripheral neuropathy', Neurological Sciences, 42, pp. 4109 - 4121, http://dx.doi.org/10.1007/s10072-021-05576-6

Di Lazzaro V; Bella R; Benussi A; Bologna M; Borroni B; Capone F; Chen KHS; Chen R; Chistyakov AV; Classen J; Kiernan MC; Koch G; Lanza G; Lefaucheur JP; Matsumoto H; Nguyen JP; Orth M; Pascual-Leone A; Rektorova I; Simko P; Taylor JP; Tremblay S; Ugawa Y; Dubbioso R; Ranieri F, 2021, 'Diagnostic contribution and therapeutic perspectives of transcranial magnetic stimulation in dementia', Clinical Neurophysiology, 132, pp. 2568 - 2607, http://dx.doi.org/10.1016/j.clinph.2021.05.035

Vucic S; Henderson RD; Mathers S; Needham M; Schultz D; Kiernan MC; Mekhael L; Ryder J; Orden B; Menon P; Pavey N; Higashihara M; Dharmadasa T; Huynh W; Ramsey E; Zoing M; Mazumder S; Thornton N; Hall LA; Allcroft P; Toubia M; Hopkins S, 2021, 'Safety and efficacy of dimethyl fumarate in ALS: randomised controlled study', Annals of Clinical and Translational Neurology, 8, pp. 1991 - 1999, http://dx.doi.org/10.1002/acn3.51446

Cudkowicz M; Genge A; Maragakis N; Petri S; van den Berg L; Aho VV; Sarapohja T; Kuoppamäki M; Garratt C; Al-Chalabi A; Kiernan M; Mathers S; Henderson R; Needham M; Schultz D; Löscher W; Mitrovic N; Rath J; Damme PV; De Bleecker JL; Delstanche S; Johnston W; Zinman L; O'Connell C; Matte G; Dionne A; Korngut L; Turnbull J; Laaksovirta H; Jokela M; Tapiola T; Soriani MH; Couratier P; Camu W; Corcia P; Ludolph A; Großkreutz J; Meyer T; Boentert M; Schrank B; Prudlo J; Untucht R; Hardiman O; Siciliano G; Chio' A; Mazzini L; Inghilleri M; Caponnetto C; Mora G; Mora Pardina JS; Farrero Munoz E; Vázquez Costa JF; Aguera Morales E; Varona L; Andersen P; Ingre C; Johansson R; Radunovic A; Young C; Babu S; Shaibani A; Staff N; Vu T; Rivner M; Scelsa S; Sivakumar K; Waheed W; Heitzman D; Rana S; Pattee G; Ajroud-Driss S; Bayat E; Kasarskis E; Lange DJ; Elliott M; Harris B; Felice K; Pulley MT; Kwan J; Brown M; Ravits J; Burford M; Karam C; Miller T; Andrews J; Levine T; Locatelli E; Wymer J; Bedlack R; Fee D; Goyal N; Oskarsson B; McCluskey L; Caress J; Weiss M; Quick A; Bromberg M; Lacomis D; Goutman S; Rezania K, 2021, 'Safety and efficacy of oral levosimendan in people with amyotrophic lateral sclerosis (the REFALS study): a randomised, double-blind, placebo-controlled phase 3 trial', The Lancet Neurology, 20, pp. 821 - 831, http://dx.doi.org/10.1016/S1474-4422(21)00242-8

Caga J; Devenney E; Huynh W; Zoing MC; Ahmed RM; Kiernan MC, 2021, 'Illness Cognitions in ALS: New Insights Into Clinical Management of Behavioural Symptoms', Frontiers in Neurology, 12, http://dx.doi.org/10.3389/fneur.2021.740693

Kang A; Arnold R; Gallagher M; Snelling P; Green J; Fernando M; Kiernan MC; Hand S; Grimley K; Burman J; Heath A; Rogers K; Bhattacharya A; Smyth B; Bradbury T; Hawley C; Perkovic V; Krishnan AV; Jardine MJ, 2021, 'Effect of hemodiafiltration on the progression of neuropathy with kidney failure: A randomized controlled trial', Clinical Journal of the American Society of Nephrology, 16, pp. 1365 - 1375, http://dx.doi.org/10.2215/CJN.17151120

Suzuki YI; Ma Y; Shibuya K; Misawa S; Suichi T; Tsuneyama A; Nakamura K; Matamala JM; Dharmadasa T; Vucic S; Fan D; Kiernan MC; Kuwabara S, 2021, 'Effect of racial background on motor cortical function as measured by threshold tracking transcranial magnetic stimulation', Journal of Neurophysiology, 126, pp. 840 - 844, http://dx.doi.org/10.1152/jn.00083.2021

Vucic S; Pavey N; Haidar M; Turner BJ; Kiernan MC, 2021, 'Cortical hyperexcitability: Diagnostic and pathogenic biomarker of ALS', Neuroscience Letters, 759, http://dx.doi.org/10.1016/j.neulet.2021.136039

McManus L; Lowery M; Merletti R; Søgaard K; Besomi M; Clancy EA; van Dieën JH; Hug F; Wrigley T; Besier T; Carson RG; Disselhorst-Klug C; Enoka RM; Falla D; Farina D; Gandevia S; Holobar A; Kiernan MC; McGill K; Perreault E; Rothwell JC; Tucker K; Hodges PW, 2021, 'Consensus for experimental design in electromyography (CEDE) project: Terminology matrix', Journal of Electromyography and Kinesiology, 59, pp. 102565, http://dx.doi.org/10.1016/j.jelekin.2021.102565

Nathani D; Spies J; Barnett MH; Pollard J; Wang MX; Sommer C; Kiernan MC, 2021, 'Nerve biopsy: Current indications and decision tools', Muscle and Nerve, 64, pp. 125 - 139, http://dx.doi.org/10.1002/mus.27201

Devenney EM; Tu S; Caga J; Ahmed RM; Ramsey E; Zoing M; Kwok J; Halliday GM; Piguet O; Hodges JR; Kiernan MC, 2021, 'Neural mechanisms of psychosis vulnerability and perceptual abnormalities in the ALS-FTD spectrum', Annals of Clinical and Translational Neurology, 8, pp. 1576 - 1591, http://dx.doi.org/10.1002/acn3.51363

Kiernan MC, 2021, 'Neurology and clinical neurophysiology: An artificial divide', Practical Neurology, 21, pp. 274 - 275, http://dx.doi.org/10.1136/practneurol-2021-002946

Tu S; Huang M; Caga J; Mahoney CJ; Kiernan MC, 2021, 'Brainstem Correlates of Pathological Laughter and Crying Frequency in ALS', Frontiers in Neurology, 12, http://dx.doi.org/10.3389/fneur.2021.704059

Forrest SL; Kim JH; De Sousa C; Cheong R; Crockford DR; Sheedy D; Stevens J; McCrossin T; Tan RH; McCann H; Shepherd CE; Rowe DB; Kiernan MC; Halliday GM; Kril JJ, 2021, 'Coexisting Lewy body disease and clinical parkinsonism in amyotrophic lateral sclerosis', European Journal of Neurology, 28, pp. 2192 - 2199, http://dx.doi.org/10.1111/ene.14849

Fifita JA; Chan Moi Fat S; McCann EP; Williams KL; Twine NA; Bauer DC; Rowe DB; Pamphlett R; Kiernan MC; Tan VX; Blair IP; Guillemin GJ, 2021, 'Genetic Analysis of Tryptophan Metabolism Genes in Sporadic Amyotrophic Lateral Sclerosis', Frontiers in Immunology, 12, http://dx.doi.org/10.3389/fimmu.2021.701550

Ahmed RM; Kiernan MC, 2021, 'Author Response: Phenotypic Variability in ALS-FTD and Effect on Survival', Neurology, 96, pp. 1103 - 1104, http://dx.doi.org/10.1212/WNL.0000000000012073

Nguyen C; Caga J; Mahoney CJ; Kiernan MC; Huynh W, 2021, 'Behavioural changes predict poorer survival in amyotrophic lateral sclerosis', Brain and Cognition, 150, http://dx.doi.org/10.1016/j.bandc.2021.105710

Ahmed RM; Tse NY; Chen Y; Henning E; Hodges JR; Kiernan MC; Irish M; Farooqi IS; Piguet O, 2021, 'Neural correlates of fat preference in frontotemporal dementia: translating insights from the obesity literature', Annals of Clinical and Translational Neurology, 8, pp. 1318 - 1329, http://dx.doi.org/10.1002/acn3.51369

Hannaford A; Pavey N; van den Bos M; Geevasinga N; Menon P; Shefner JM; Kiernan MC; Vucic S, 2021, 'Diagnostic Utility of Gold Coast Criteria in Amyotrophic Lateral Sclerosis', Annals of Neurology, 89, pp. 979 - 986, http://dx.doi.org/10.1002/ana.26045

Chan Moi Fat S; McCann EP; Williams KL; Henden L; Twine NA; Bauer DC; Pamphlett R; Kiernan MC; Rowe DB; Nicholson GA; Fifita JA; Blair IP, 2021, 'Genetic analysis of GLT8D1 and ARPP21 in Australian familial and sporadic amyotrophic lateral sclerosis', Neurobiology of Aging, 101, pp. 297.e9 - 297.e11, http://dx.doi.org/10.1016/j.neurobiolaging.2021.01.005

Mahoney CJ; Ahmed RM; Huynh W; Tu S; Rohrer JD; Bedlack RS; Hardiman O; Kiernan MC, 2021, 'Pathophysiology and Treatment of Non-motor Dysfunction in Amyotrophic Lateral Sclerosis', CNS Drugs, 35, pp. 483 - 505, http://dx.doi.org/10.1007/s40263-021-00820-1

Timmins HC; Li T; Trinh T; Kiernan MC; Harrison M; Boyle F; Friedlander M; Goldstein D; Park SB, 2021, 'Weekly Paclitaxel-Induced Neurotoxicity in Breast Cancer: Outcomes and Dose Response', Oncologist, 26, pp. 366 - 374, http://dx.doi.org/10.1002/onco.13697

Higashihara M; Pavey N; Van Den Bos M; Menon P; Kiernan MC; Vucic S, 2021, 'Association of Cortical Hyperexcitability and Cognitive Impairment in Patients With Amyotrophic Lateral Sclerosis', Neurology, 96, pp. E2090 - E2097, http://dx.doi.org/10.1212/WNL.0000000000011798

Garcia-Montojo M; Fathi S; Norato G; Smith BR; Rowe DB; Kiernan MC; Vucic S; Mathers S; van Eijk RPA; Santamaria U; Rogers ML; Malaspina A; Lombardi V; Mehta PR; Westeneng HJ; van den Berg LH; Al-Chalabi A; Gold J; Nath A, 2021, 'Inhibition of HERV-K (HML-2) in amyotrophic lateral sclerosis patients on antiretroviral therapy', Journal of the Neurological Sciences, 423, http://dx.doi.org/10.1016/j.jns.2021.117358

Huynh W; Tu S; Mahoney CJ; Schwartz R; Kiernan MC, 2021, 'Mills Syndrome: Clinical and Radiologic Asymmetry', Neurology, 96, pp. 677 - 678, http://dx.doi.org/10.1212/WNL.0000000000011710

van den Bos MAJ; Higashihara M; Geevasinga N; Menon P; Kiernan MC; Vucic S, 2021, 'Pathophysiological associations of transcallosal dysfunction in ALS', European Journal of Neurology, 28, pp. 1172 - 1180, http://dx.doi.org/10.1111/ene.14653

El-Wahsh S; Finger EC; Piguet O; Mok V; Rohrer JD; Kiernan MC; Ahmed RM, 2021, 'Predictors of survival in frontotemporal lobar degeneration syndromes', Journal of Neurology, Neurosurgery and Psychiatry, 92, pp. 425 - 433, http://dx.doi.org/10.1136/jnnp-2020-324349

Weiss MD; Macklin EA; McIlduff CE; Vucic S; Wainger BJ; Kiernan MC; Goutman SA; Goyal NA; Rutkove SB; Ladha SS; Chen IHA; Harms MB; Brannagan TH; Lacomis D; Zivkovic S; Ma M; Wang LH; Simmons Z; Rivner MH; Shefner JM; Cudkowicz ME; Atassi N, 2021, 'Effects of mexiletine on hyperexcitability in sporadic amyotrophic lateral sclerosis: Preliminary findings from a small phase II randomized controlled trial', Muscle and Nerve, 63, pp. 371 - 383, http://dx.doi.org/10.1002/mus.27146

Wainger BJ; Macklin EA; Vucic S; McIlduff CE; Paganoni S; Maragakis NJ; Bedlack R; Goyal NA; Rutkove SB; Lange DJ; Rivner MH; Goutman SA; Ladha SS; Mauricio EA; Baloh RH; Simmons Z; Pothier L; Kassis SB; La T; Hall M; Evora A; Klements D; Hurtado A; Pereira JD; Koh J; Celnik PA; Chaudhry V; Gable K; Juel VC; Phielipp N; Marei A; Rosenquist P; Meehan S; Oskarsson B; Lewis RA; Kaur D; Kiskinis E; Woolf CJ; Eggan K; Weiss MD; Berry JD; David WS; Davila-Perez P; Camprodon JA; Pascual-Leone A; Kiernan MC; Shefner JM; Atassi N; Cudkowicz ME, 2021, 'Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial', JAMA Neurology, 78, pp. 186 - 196, http://dx.doi.org/10.1001/jamaneurol.2020.4300

McCann EP; Henden L; Fifita JA; Zhang KY; Grima N; Bauer DC; Chan Moi Fat S; Twine NA; Pamphlett R; Kiernan MC; Rowe DB; Williams KL; Blair IP, 2021, 'Evidence for polygenic and oligogenic basis of Australian sporadic amyotrophic lateral sclerosis', Journal of Medical Genetics, 58, pp. 87 - 95, http://dx.doi.org/10.1136/jmedgenet-2020-106866

Kiernan MC; Vucic S; Talbot K; McDermott CJ; Hardiman O; Shefner JM; Al-Chalabi A; Huynh W; Cudkowicz M; Talman P; Van den Berg LH; Dharmadasa T; Wicks P; Reilly C; Turner MR, 2021, 'Improving clinical trial outcomes in amyotrophic lateral sclerosis', Nature Reviews Neurology, 17, pp. 104 - 118, http://dx.doi.org/10.1038/s41582-020-00434-z

Trinh T; Park SB; Murray J; Pickering H; Lin CSY; Martin A; Friedlander M; Kiernan MC; Goldstein D; Krishnan AV, 2021, 'Neu-horizons: neuroprotection and therapeutic use of riluzole for the prevention of oxaliplatin-induced neuropathy—a randomised controlled trial', Supportive Care in Cancer, 29, pp. 1103 - 1110, http://dx.doi.org/10.1007/s00520-020-05591-x

Vucic S; Kiernan MC; Menon P; Huynh W; Rynders A; Ho KS; Glanzman R; Hotchkin MT, 2021, 'Study protocol of RESCUE-ALS: A Phase 2, randomised, double-blind, placebo-controlled study in early symptomatic amyotrophic lateral sclerosis patients to assess bioenergetic catalysis with CNM-Au8 as a mechanism to slow disease progression', BMJ open, 11, pp. e041479, http://dx.doi.org/10.1136/bmjopen-2020-041479

Shefner JM; Andrews JA; Genge A; Jackson C; Lechtzin N; Miller TM; Cockroft BM; Meng L; Wei J; Wolff AA; Malik FI; Bodkin C; Brooks BR; Caress J; Dionne A; Fee D; Goutman SA; Goyal NA; Hardiman O; Hayat G; Heiman-Patterson T; Heitzman D; Henderson RD; Johnston W; Karam C; Kiernan MC; Kolb SJ; Korngut L; Ladha S; Matte G; Mora JS; Needham M; Oskarsson B; Pattee GL; Pioro EP; Pulley M; Quan D; Rezania K; Schellenberg KL; Schultz D; Shoesmith C; Simmons Z; Statland J; Sultan S; Swenson A; Berg LHVD; Vu T; Vucic S; Weiss M; Whyte-Rayson A; Wymer J; Zinman L; Rudnicki SA, 2021, 'A Phase 2, Double-Blind, Randomized, Dose-Ranging Trial Of Reldesemtiv In Patients With ALS', Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 22, pp. 287 - 299, http://dx.doi.org/10.1080/21678421.2020.1822410

Bedlack R; Armon C; Barkhaus P; Barnes B; Bereman M; Bertorini T; Carter G; Chen A; Crayle J; Cudkowicz M; Jackson C; Kiernan M; Levitsky G; McDermott C; Pattee G; Pioro E; Salmon K; Staats K; Stephens J; Wicks P, 2021, 'ALSUntangled 57: Vinpocetine', Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 22, pp. 316 - 319, http://dx.doi.org/10.1080/21678421.2020.1786942

Dharmadasa T; Howells J; Matamala JM; Simon NG; Burke D; Vucic S; Kiernan MC, 2021, 'Cortical inexcitability defines an adverse clinical profile in amyotrophic lateral sclerosis', European Journal of Neurology, 28, pp. 90 - 97, http://dx.doi.org/10.1111/ene.14515

Rinaldi S; Davies A; Fehmi J; Beadnall HN; Wang J; Hardy TA; Barnett MH; Broadley SA; Waters P; Reddel SW; Irani SR; Brilot F; Dale RC; Ramanathan S, 2021, 'Overlapping central and peripheral nervous system syndromes in MOG antibody-associated disorders', Neurology(R) neuroimmunology & neuroinflammation, 8, http://dx.doi.org/10.1212/NXI.0000000000000924

Caga J; Zoing MC; Foxe D; Ramsey E; D’Mello M; Mioshi E; Ahmed RM; Kiernan MC; Piguet O, 2021, 'Problem-focused coping underlying lower caregiver burden in ALS-FTD: implications for caregiver intervention', Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 22, pp. 434 - 441, http://dx.doi.org/10.1080/21678421.2020.1867180

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