By Scientia Professor Matthew Colm Kiernan

Journal articles

Geevasinga N; Menon P; Ng K; Kiernan MC; Vucic S, 2016, '12. Riluzole exerts short-term effects on cortical hyperexcitability in sporadic ALS', Clinical Neurophysiology, 127, pp. e14 - e14, http://dx.doi.org/10.1016/j.clinph.2015.11.032

Howells J; Park SB; Burke D; Kiernan MC, 2016, '18. Dysfunctional properties of single motor units in ALS', Clinical Neurophysiology, 127, pp. e16 - e16, http://dx.doi.org/10.1016/j.clinph.2015.11.038

J. van den Bos MA; Menon P; Geevasinga N; Kiernan MC; Vucic S, 2016, '19. Cortical hyperexcitability in ALS: A heterogeneous process', Clinical Neurophysiology, 127, pp. e17 - e17, http://dx.doi.org/10.1016/j.clinph.2015.11.039

Farrar MA; Vucic S; Nicholson G; Kiernan MC, 2016, '3. Cortical dysfunction in Machado–Jospeh disease', Clinical Neurophysiology, 127, pp. e11 - e11, http://dx.doi.org/10.1016/j.clinph.2015.11.023

Timmins HC; Cheah BC; Lin CSY; Vucic S; Kiernan MC; Park SB, 2016, '5. Neurophysiological measures correlate with functional outcomes in ALS', Clinical Neurophysiology, 127, pp. e11 - e11, http://dx.doi.org/10.1016/j.clinph.2015.11.025

Shibuya K; Park SB; Geevasinga N; Huynh W; Simon NG; Menon P; Howells J; Garg N; Noto Y-I; Iwai Y; Nicholson GA; Vucic S; Kuwabara S; Kiernan MC, 2016, '7. Pathophysiological basis of motor neuronal hyperexcitability in amyotrophic lateral sclerosis', Clinical Neurophysiology, 127, pp. e12 - e12, http://dx.doi.org/10.1016/j.clinph.2015.11.027

Hornberger M; Kiernan MC, 2016, 'Emergence of an imaging biomarker for amyotrophic lateral sclerosis: is the end point near?', Journal of Neurology, Neurosurgery & Psychiatry, 87, pp. 569 - 569, http://dx.doi.org/10.1136/jnnp-2015-312882

Kwai NCG; Arnold R; Poynten AM; Howells J; Kiernan MC; Lin CSY; Krishnan AV, 2016, 'In vivo evidence of reduced nodal and paranodal conductances in type 1 diabetes', Clinical Neurophysiology, 127, pp. 1700 - 1706, http://dx.doi.org/10.1016/j.clinph.2015.11.047

Park SB; Vucic S; Cheah BC; Lin CSY; Kirby A; Mann KP; Zoing MC; Winhammar J; Kiernan MC, 2015, 'Flecainide in Amyotrophic Lateral Sclerosis as a Neuroprotective Strategy (FANS): A Randomized Placebo-Controlled Trial', EBioMedicine, 2, pp. 1916 - 1922, http://dx.doi.org/10.1016/j.ebiom.2015.11.022

Arnold R; Huynh W; Kiernan MC; Krishnan AV, 2015, 'Ion channel modulation as a therapeutic approach in multiple sclerosis', Current Medicinal Chemistry, 22, pp. 4366 - 4378, http://dx.doi.org/10.2174/0929867322666151029104452

Lu R; Kiernan MC; Murray A; Rosner MH; Ronco C, 2015, 'Kidney-brain crosstalk in the acute and chronic setting', Nature Reviews Nephrology, 11, pp. 707 - 719, http://dx.doi.org/10.1038/nrneph.2015.131

Kiernan MC; Turner MR, 2015, 'Lou Gehrig and the ALS split hand', Neurology, 85, pp. 1995, http://dx.doi.org/10.1212/WNL.0000000000002172

Devenney E; Bartley L; Hoon C; O'Callaghan C; Kumfor F; Hornberger M; Kwok JB; Halliday GM; Kiernan MC; Piguet O; Hodges JR, 2015, 'Progression in behavioral variant frontotemporal dementia: A longitudinal study', JAMA Neurology, 72, pp. 1501 - 1509, http://dx.doi.org/10.1001/jamaneurol.2015.2061

Geevasinga N; Menon P; Nicholson GA; Ng K; Howells J; Kril JJ; Yiannikas C; Kiernan MC; Vucic S, 2015, 'Cortical function in asymptomatic carriers and patients with C9Orf72 amyotrophic lateral sclerosis', JAMA Neurology, 72, pp. 1268 - 1274, http://dx.doi.org/10.1001/jamaneurol.2015.1872

Sillence KA; Roberts LA; Hollands HJ; Thompson HP; Kiernan M; Madgett TE; Welch CR; Avent ND, 2015, 'Fetal Sex and RHD Genotyping with Digital PCR Demonstrates Greater Sensitivity than Real-time PCR', CLINICAL CHEMISTRY, 61, pp. 1399 - 1407, http://dx.doi.org/10.1373/clinchem.2015.239137

Simon NG; Kiernan MC, 2015, 'Precise correlation between structural and electrophysiological disturbances in MADSAM neuropathy', Neuromuscular Disorders, 25, pp. 904 - 907, http://dx.doi.org/10.1016/j.nmd.2015.07.012

Ke YD; van Hummel A; Stevens CH; Gladbach A; Ippati S; Bi M; Lee WS; Krüger S; van der Hoven J; Volkerling A; Bongers A; Halliday G; Haass NK; Kiernan M; Delerue F; Ittner LM, 2015, 'Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS', Acta Neuropathologica, 130, pp. 661 - 678, http://dx.doi.org/10.1007/s00401-015-1486-0

Ahmed RM; Latheef S; Bartley L; Irish M; Halliday GM; Kiernan MC; Hodges JR; Piguet O, 2015, 'Eating behavior in frontotemporal dementia', Neurology, 85, pp. 1310 - 1317, http://dx.doi.org/10.1212/WNL.0000000000002018

Linnane B; Kearse L; O'Connell NH; Fenton J; Kiernan MG; Dunne CP, 2015, 'A case of failed eradication of cystic fibrosis-related sinus colonisation by Pseudomonas aeruginosa', BMC PULMONARY MEDICINE, 15, http://dx.doi.org/10.1186/s12890-015-0113-0

Hogden A; Greenfield D; Nugus P; Kiernan MCS, 2015, 'Development of a model to guide decision making in amyotrophic lateral sclerosis multidisciplinary care', Health Expectations, 18, pp. 1769 - 1782, http://dx.doi.org/10.1111/hex.12169

Simon NG; Huynh W; Vucic S; Talbot K; Kiernan MC, 2015, 'Motor neuron disease: Current management and future prospects', Internal Medicine Journal, 45, pp. 1005 - 1013, http://dx.doi.org/10.1111/imj.12874

Tan RH; Kril JJ; Fatima M; McGeachie A; McCann H; Shepherd C; Forrest SL; Affleck A; Kwok JBJ; Hodges JR; Kiernan MC; Halliday GM, 2015, 'TDP-43 proteinopathies: Pathological identification of brain regions differentiating clinical phenotypes', Brain, 138, pp. 3110 - 3122, http://dx.doi.org/10.1093/brain/awv220

Ahmed RM; Iodice V; Daveson N; Kiernan MC; Piguet O; Hodges JR, 2015, 'Autonomic dysregulation in frontotemporal dementia', Journal of Neurology, Neurosurgery and Psychiatry, 86, pp. 1048 - 1049, http://dx.doi.org/10.1136/jnnp-2014-309424

Mathey EK; Park SB; Hughes RAC; Pollard JD; Armati PJ; Barnett MH; Taylor BV; Dyck PJB; Kiernan MC; Lin CSY, 2015, 'Chronic inflammatory demyelinating polyradiculoneuropathy: From pathology to phenotype', Journal of Neurology, Neurosurgery and Psychiatry, 86, pp. 973 - 985, http://dx.doi.org/10.1136/jnnp-2014-309697

Caga J; Ramsey E; Hogden A; Mioshi E; Kiernan MC, 2015, 'A longer diagnostic interval is a risk for depression in amyotrophic lateral sclerosis', Palliative and Supportive Care, 13, pp. 1019 - 1024, http://dx.doi.org/10.1017/S1478951514000881

Simon NG; Ralph JW; Lomen-Hoerth C; Poncelet AN; Vucic S; Kiernan MC; Kliot M, 2015, 'Quantitative ultrasound of denervated hand muscles', Muscle and Nerve, 52, pp. 221 - 230, http://dx.doi.org/10.1002/mus.24519

Devenney E; Foxe D; Dobson-Stone C; Kwok JB; Kiernan MC; Hodges JR, 2015, 'Clinical heterogeneity of the C9orf72 genetic mutation in frontotemporal dementia', Neurocase, 21, pp. 535 - 541, http://dx.doi.org/10.1080/13554794.2014.951058

Kiernan M; Bhogal M; Wong K; Sivaprakasam R; Ashman N; Ali N, 2015, 'Sight-threatening intraocular pressure due to an upper arm dialysis fistula', LANCET, 386, pp. 101 - 102, http://dx.doi.org/10.1016/S0140-6736(15)61003-0

Huynh W; Kiernan MC, 2015, 'A unique account of ALS in China: Exploring ethnic heterogeneity', Journal of Neurology, Neurosurgery and Psychiatry, http://dx.doi.org/10.1136/jnnp-2015-311293

Eisen A; Lemon R; Kiernan MC; Hornberger M; Turner MR, 2015, 'Does dysfunction of the mirror neuron system contribute to symptoms in amyotrophic lateral sclerosis?', Clinical Neurophysiology, 126, pp. 1288 - 1294, http://dx.doi.org/10.1016/j.clinph.2015.02.003

Ahmed RM; Kaizik C; Irish M; Mioshi E; Dermody N; Kiernan MC; Piguet O; Hodges JR, 2015, 'Characterizing sexual behavior in frontotemporal dementia', Journal of Alzheimer's Disease, 46, pp. 677 - 686, http://dx.doi.org/10.3233/JAD-150034

Simon NG; Lee M; Bae JS; Mioshi E; Lin CSY; Pfluger CM; Henderson RD; Vucic S; Swash M; Burke D; Kiernan MC, 2015, 'Dissociated lower limb muscle involvement in amyotrophic lateral sclerosis', Journal of Neurology, 262, pp. 1424 - 1432, http://dx.doi.org/10.1007/s00415-015-7721-8

Ittner LM; Halliday GM; Kril JJ; Götz J; Hodges JR; Kiernan MC, 2015, 'FTD and ALS-translating mouse studies into clinical trials', Nature Reviews Neurology, 11, pp. 360 - 366, http://dx.doi.org/10.1038/nrneurol.2015.65

Wang C; Paling D; Chen L; Hatton SN; Lagopoulos J; Aw ST; Kiernan MC; Barnett MH, 2015, 'Axonal conduction in multiple sclerosis: A combined magnetic resonance imaging and electrophysiological study of the medial longitudinal fasciculus', Multiple Sclerosis, 21, pp. 905 - 915, http://dx.doi.org/10.1177/1352458514556301

Borden M; Kiernan MS; Duc TP; DeNofrio D; Sylvia L, 2015, 'Bridging with half-therapeutic dose enoxaparin in outpatients with left ventricular assist devices and sub-therapeutic international normalized ratios', JOURNAL OF HEART AND LUNG TRANSPLANTATION, 34, pp. 860 - 862, http://dx.doi.org/10.1016/j.healun.2015.01.981

Menon P; Geevasinga N; Yiannikas C; Howells J; Kiernan MC; Vucic S, 2015, 'Sensitivity and specificity of threshold tracking transcranial magnetic stimulation for diagnosis of amyotrophic lateral sclerosis: a prospective study (vol 14, pg 478, 2015)', LANCET NEUROLOGY, 14, pp. 566 - 566, http://dx.doi.org/10.1016/S1474-4422(15)00014-9

Swash M; Kiernan MC, 2015, 'Measuring change in amyotrophic lateral sclerosis', Journal of Neurology, Neurosurgery and Psychiatry, 86, pp. 1169 - 1170, http://dx.doi.org/10.1136/jnnp-2015-311051

Geevasinga N; Menon P; Sue CM; Kumar KR; Ng K; Yiannikas C; Kiernan MC; Vucic S, 2015, 'Cortical excitability changes distinguish the motor neuron disease phenotypes from hereditary spastic paraplegia', European Journal of Neurology, 22, pp. 826 - e58, http://dx.doi.org/10.1111/ene.12669

Devenney E; Vucic S; Hodges JR; Kiernan MC, 2015, 'Motor neuron disease-frontotemporal dementia: A clinical continuum', Expert Review of Neurotherapeutics, 15, pp. 509 - 522, http://dx.doi.org/10.1586/14737175.2015.1034108

Menon P; Geevasinga N; Yiannikas C; Howells J; Kiernan MC; Vucic S, 2015, 'Sensitivity and specificity of threshold tracking transcranial magnetic stimulation for diagnosis of amyotrophic lateral sclerosis: A prospective study', The Lancet Neurology, 14, pp. 478 - 484, http://dx.doi.org/10.1016/S1474-4422(15)00014-9

Lee M; Kiernan MC; Macefield VG; Lee BB; Lin CSY, 2015, 'Short-term peripheral nerve stimulation ameliorates axonal dysfunction after spinal cord injury', Journal of Neurophysiology, 113, pp. 3209 - 3218, http://dx.doi.org/10.1152/jn.00839.2014

Turner MR; Kiernan MC, 2015, 'The standard of care in amyotrophic lateral sclerosis:A centralised multidisciplinary clinic encounter sets a new benchmark for a uniquely challenging neurodegenerative disorder', Journal of Neurology, Neurosurgery and Psychiatry, 86, pp. 481 - 482, http://dx.doi.org/10.1136/jnnp-2014-309829

Ahmed R; Henning E; Bartley L; Halliday G; Piguet O; Farooqi S; Hodges J; Kiernan M, 2015, 'Eating Behaviour and Metabolic Changes across the Spectrum of Motor Neuron Disease and Frontotemporal Dementia. (I12-5E)', Neurology, 84, http://dx.doi.org/10.1212/wnl.84.14_supplement.i12-5e

Ahmed R; Henning E; Bartley L; Halliday G; Piguet O; Farooqi S; Hodges J; Kiernan M, 2015, 'Eating Behaviour and Metabolic Changes across the Spectrum of Motor Neuron Disease and Frontotemporal Dementia. (P1.225)', Neurology, 84, http://dx.doi.org/10.1212/wnl.84.14_supplement.p1.225

Geevasinga N; Menon P; Yiannikas C; Howells J; Kiernan M; Vucic S, 2015, 'Threshold tracking TMS: A novel diagnostic technique for Amyotrophic Lateral Sclerosis (I8-5C)', Neurology, 84, http://dx.doi.org/10.1212/wnl.84.14_supplement.i8-5c

Geevasinga N; Menon P; Yiannikas C; Howells J; Kiernan M; Vucic S, 2015, 'Threshold tracking TMS: A novel diagnostic technique for Amyotrophic Lateral Sclerosis (S24.005)', Neurology, 84, http://dx.doi.org/10.1212/wnl.84.14_supplement.s24.005

Menon P; Kiernan MC; Vucic S, 2015, 'Cortical hyperexcitability precedes lower motor neuron dysfunction in ALS', Clinical Neurophysiology, 126, pp. 803 - 809, http://dx.doi.org/10.1016/j.clinph.2014.04.023

Kiernan MC, 2015, 'Palliative care in amyotrophic lateral sclerosis', The Lancet Neurology, 14, pp. 347 - 348, http://dx.doi.org/10.1016/S1474-4422(14)70289-3

Simon NG; Lin CSY; Lee M; Howells J; Vucic S; Burke D; Kiernan MC, 2015, 'Segmental motoneuronal dysfunction is a feature of amyotrophic lateral sclerosis', Clinical Neurophysiology, 126, pp. 828 - 836, http://dx.doi.org/10.1016/j.clinph.2014.07.029

Farrar MA; Kiernan MC, 2015, 'The Genetics of Spinal Muscular Atrophy: Progress and Challenges', Neurotherapeutics, 12, pp. 290 - 302, http://dx.doi.org/10.1007/s13311-014-0314-x

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