By Associate Professor Orazio Vittorio

Journal articles

Ung C; Tsoli M; Liu J; Cassano D; Pocoví-Martínez S; Upton DH; Ehteda A; Mansfeld FM; Failes TW; Farfalla A; Katsinas C; Kavallaris M; Arndt GM; Vittorio O; Cirillo G; Voliani V; Ziegler DS, 2021, 'Doxorubicin-loaded gold nanoarchitectures as a therapeutic strategy against diffuse intrinsic pontine glioma', Cancers, 13, pp. 1 - 20, http://dx.doi.org/10.3390/cancers13061278

Curcio M; Cirillo G; Saletta F; Michniewicz F; Nicoletta FP; Vittorio O; Hampel S; Iemma F, 2021, 'Carbon Nanohorns as Effective Nanotherapeutics in Cancer Therapy', C-JOURNAL OF CARBON RESEARCH, 7, http://dx.doi.org/10.3390/c7010003

Michniewicz F; Saletta F; Rouen J; Ziegler D; Vittorio O, 2020, 'DIPG-83. USING COPPER CHELATING AGENTS TO TARGET RECEPTOR TYROSINE KINASE SIGNALLING IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', Neuro-Oncology, 22, pp. iii303 - iii303, http://dx.doi.org/10.1093/neuonc/noaa222.124

Curcio M; Cirillo G; Rouaen JRC; Saletta F; Nicoletta FP; Vittorio O; Iemma F, 2020, 'Natural polysaccharide carriers in brain delivery: Challenge and perspective', Pharmaceutics, 12, http://dx.doi.org/10.3390/pharmaceutics12121183

Voli F; Valli E; Lerra L; Kimpton K; Saletta F; Giorgi FM; Mercatelli D; Rouaen JRC; Shen S; Murray JE; Ahmed-Cox A; Cirillo G; Mayoh C; Beavis PA; Haber M; Trapani JA; Kavallaris M; Vittorio O, 2020, 'Intratumoral copper modulates PD-L1 expression and influences tumor immune evasion', Cancer Research, 80, pp. 4129 - 4144, http://dx.doi.org/10.1158/0008-5472.CAN-20-0471

Curcio M; Farfalla A; Saletta F; Valli E; Pantuso E; Nicoletta FP; Iemma F; Vittorio O; Cirillo G, 2020, 'Functionalized carbon nanostructures versus drug resistance: Promising scenarios in cancer treatment', Molecules, 25, http://dx.doi.org/10.3390/molecules25092102

Curcio M; Cirillo G; Tucci P; Farfalla A; Bevacqua E; Vittorio O; Iemma F; Nicoletta FP, 2020, 'Dextran-curcumin nanoparticles as a methotrexate delivery vehicle: A step forward in breast cancer combination therapy', Pharmaceuticals, 13, http://dx.doi.org/10.3390/ph13010002

Le Grand M; Mukha A; Püschel J; Valli E; Kamili A; Vittorio O; Dubrovska A; Kavallaris M, 2020, 'Interplay between MycN and c-Myc regulates radioresistance and cancer stem cell phenotype in neuroblastoma upon glutamine deprivation', Theranostics, 10, pp. 6411 - 6429, http://dx.doi.org/10.7150/thno.42602

Liu A; Cohen J; Vittorio O, 2019, 'Poor dietary polyphenol intake in childhood cancer patients', Nutrients, 11, http://dx.doi.org/10.3390/nu11112835

Cirillo G; Vittorio O; Kunhardt D; Valli E; Voli F; Farfalla A; Curcio M; Spizzirri UG; Hampel S, 2019, 'Combining carbon nanotubes and chitosan for the vectorization of methotrexate to lung cancer cells', Materials, 12, http://dx.doi.org/10.3390/ma12182889

Makharza SA; Cirillo G; Vittorio O; Valli E; Voli F; Farfalla A; Curcio M; Iemma F; Nicoletta FP; El-Gendy AA; Goya GF; Hampel S, 2019, 'Magnetic graphene oxide nanocarrier for targeted delivery of cisplatin: A perspective for glioblastoma treatment', Pharmaceuticals, 12, http://dx.doi.org/10.3390/ph12020076

Cirillo G; Curcio M; Spizzirri UG; Vittorio O; Valli E; Farfalla A; Leggio A; Nicoletta FP; Iemma F, 2019, 'Chitosan–Quercetin Bioconjugate as Multi-Functional Component of Antioxidants and Dual-Responsive Hydrogel Networks', Macromolecular Materials and Engineering, 304, http://dx.doi.org/10.1002/mame.201800728

Di Luca M; Curcio M; Valli E; Cirillo G; Voli F; Butini ME; Farfalla A; Pantuso E; Leggio A; Nicoletta FP; Tavanti A; Iemma F; Vittorio O, 2019, 'Combining antioxidant hydrogels with self-assembled microparticles for multifunctional wound dressings', Journal of Materials Chemistry B, 7, pp. 4361 - 4370, http://dx.doi.org/10.1039/c9tb00871c

Lerra L; Farfalla A; Sanz B; Cirillo G; Vittorio O; Voli F; Grand ML; Curcio M; Nicoletta FP; Dubrovska A; Hampel S; Iemma F; Goya GF, 2019, 'Graphene oxide functional nanohybrids with magnetic nanoparticles for improved vectorization of doxorubicin to neuroblastoma cells', Pharmaceutics, 11, http://dx.doi.org/10.3390/pharmaceutics11010003

Yee EMH; Cirillo G; Brandl MB; Black DSC; Vittorio O; Kumar N, 2019, 'Synthesis of dextran–phenoxodiol and evaluation of its physical stability and biological activity', Frontiers in Bioengineering and Biotechnology, 7, http://dx.doi.org/10.3389/fbioe.2019.00183

Cirillo G; Peitzsch C; Vittorio O; Curcio M; Farfalla A; Voli F; Dubrovska A; Iemma F; Kavallaris M; Hampel S, 2019, 'When polymers meet carbon nanostructures: Expanding horizons in cancer therapy', Future Medicinal Chemistry, 11, pp. 2205 - 2231, http://dx.doi.org/10.4155/fmc-2018-0540

di Luca M; Vittorio O; Cirillo G; Curcio M; Czuban M; Voli F; Farfalla A; Hampel S; Nicoletta FP; Iemma F, 2018, 'Electro-responsive graphene oxide hydrogels for skin bandages: The outcome of gelatin and trypsin immobilization', International Journal of Pharmaceutics, 546, pp. 50 - 60, http://dx.doi.org/10.1016/j.ijpharm.2018.05.027

Vittorio O; Le Grand M; Makharza SA; Curcio M; Tucci P; Iemma F; Nicoletta FP; Hampel S; Cirillo G, 2018, 'Doxorubicin synergism and resistance reversal in human neuroblastoma BE(2)C cell lines: An in vitro study with dextran-catechin nanohybrids', European Journal of Pharmaceutics and Biopharmaceutics, 122, pp. 176 - 185, http://dx.doi.org/10.1016/j.ejpb.2017.11.005

Parmar A; Pascali G; Voli F; Lerra L; Yee E; Ahmed-Cox A; Kimpton K; Cirillo G; Arthur A; Zahra D; Rahardjo G; Liu GJ; Lengkeek N; Saletta F; Charil A; Kavallaris M; Vittorio O, 2018, 'In vivo [64Cu]CuCl2 PET imaging reveals activity of Dextran-Catechin on tumor copper homeostasis', Theranostics, 8, pp. 5645 - 5659, http://dx.doi.org/10.7150/thno.29840

Voli F; Lerra L; Kimpton K; Saletta F; Cirillo G; Kavallaris M; Vittorio O, 2018, 'Harnessing copper in cancer to enhance anti-tumor immune response', Annals of Oncology, 29, pp. x35 - x35, http://dx.doi.org/10.1093/annonc/mdy487.030

Oliver S; Yee E; Kavallaris M; Vittorio O; Boyer C, 2018, 'Water Soluble Antioxidant Dextran-Quercetin Conjugate with Potential Anticancer Properties', MACROMOLECULAR BIOSCIENCE, 18, http://dx.doi.org/10.1002/mabi.201700239

Oliver S; Jofri A; Thomas DS; Vittorio O; Kayallaris M; Boyer C, 2017, 'Tuneable catechin functionalisation of carbohydrate polymers', CARBOHYDRATE POLYMERS, 169, pp. 480 - 494, http://dx.doi.org/10.1016/j.carbpol.2017.04.032

Yee EMH; Hook JM; Bhadbhade MM; Vittorio O; Kuchel RP; Brandl MB; Tilley RD; Black DSC; Kumar N, 2017, 'Preparation, characterization and in vitro biological evaluation of (1:2) phenoxodiol-β-cyclodextrin complex', Carbohydrate Polymers, 165, pp. 444 - 454, http://dx.doi.org/10.1016/j.carbpol.2017.02.081

di Leo N; Battaglini M; Berger L; Giannaccini M; Dente L; Hampel S; Vittorio O; Cirillo G; Raffa V, 2017, 'A catechin nanoformulation inhibits WM266 melanoma cell proliferation, migration and associated neo-angiogenesis', European Journal of Pharmaceutics and Biopharmaceutics, 114, pp. 1 - 10, http://dx.doi.org/10.1016/j.ejpb.2016.12.024

Cirillo G; Curcio M; Spizzirri UG; Vittorio O; Tucci P; Picci N; Iemma F; Hampel S; Nicoletta FP, 2017, 'Carbon nanotubes hybrid hydrogels for electrically tunable release of Curcumin', European Polymer Journal, 90, pp. 1 - 12, http://dx.doi.org/10.1016/j.eurpolymj.2017.03.011

Kunz-Schughart LA; Dubrovska A; Peitzsch C; Ewe A; Aigner A; Schellenburg S; Muders MH; Hampel S; Cirillo G; Iemma F; Tietze R; Alexiou C; Stephan H; Zarschler K; Vittorio O; Kavallaris M; Parak WJ; Mädler L; Pokhrel S, 2017, 'Nanoparticles for radiooncology: Mission, vision, challenges', Biomaterials, 120, pp. 155 - 184, http://dx.doi.org/10.1016/j.biomaterials.2016.12.010

Yee EMH; Brandl MB; Black DSC; Vittorio O; Kumar N, 2017, 'Synthesis of isoflavene-thiosemicarbazone hybrids and evaluation of their anti-tumor activity', Bioorganic and Medicinal Chemistry Letters, 27, pp. 2454 - 2458, http://dx.doi.org/10.1016/j.bmcl.2017.04.002

Vittorio O; Curcio M; Cojoc M; Goya GF; Hampel S; Iemma F; Dubrovska A; Cirillo G, 2017, 'Polyphenols delivery by polymeric materials: challenges in cancer treatment.', Drug Deliv, 24, pp. 162 - 180, http://dx.doi.org/10.1080/10717544.2016.1236846

Cirillo G; Curcio M; Vittorio O; Spizzirri UG; Nicoletta FP; Picci N; Hampel S; Iemma F, 2016, 'Dual Stimuli Responsive Gelatin-CNT Hybrid Films as a Versatile Tool for the Delivery of Anionic Drugs', Macromolecular Materials and Engineering, 301, pp. 1537 - 1547, http://dx.doi.org/10.1002/mame.201600192

Parchi PD; Vittorio O; Andreani L; Battistini P; Piolanti N; Marchetti S; Poggetti A; Lisanti M, 2016, 'Nanoparticles for Tendon Healing and Regeneration: Literature Review', FRONTIERS IN AGING NEUROSCIENCE, 8, http://dx.doi.org/10.3389/fnagi.2016.00202

Vittorio O; Cojoc M; Curcio M; Spizzirri UG; Hampel S; Nicoletta FP; Iemma F; Dubrovska A; Kavallaris M; Cirillo G, 2016, 'Polyphenol Conjugates by Immobilized Laccase: The Green Synthesis of Dextran-Catechin', Macromolecular Chemistry and Physics, 217, pp. 1488 - 1492, http://dx.doi.org/10.1002/macp.201600046

Cirillo G; Spizzirri UG; Curcio M; Hampel S; Vittorio O; Restuccia D; Picci N; Iemma F, 2016, 'Carbon nanohybrids as electro-responsive drug delivery systems', Mini-Reviews in Medicinal Chemistry, 16, pp. 658 - 668, http://dx.doi.org/10.2174/1389557515666150709104444

Cirillo G; Curcio M; Vittorio O; Iemma F; Restuccia D; Spizzirri UG; Puoci F; Picci N, 2016, 'Polyphenol Conjugates and Human Health: A Perspective Review', Critical Reviews in Food Science and Nutrition, 56, pp. 326 - 337, http://dx.doi.org/10.1080/10408398.2012.752342

Vittorio O; Brandl M; Cirillo G; Kimpton K; Hinde E; Gaus K; Yee E; Kumar N; Duong H; Fleming C; Haber M; Norris M; Boyer C; Kavallaris M, 2016, 'Dextran-Catechin: An anticancer chemically-modified natural compound targeting copper that attenuates neuroblastoma growth', Oncotarget, 7, pp. 47479 - 47493, http://dx.doi.org/10.18632/oncotarget.10201

Parchi PD; Vittorio O; Andreani L; Battistini P; Piolanti N; Marchetti S; Poggetti A; Lisanti M, 2016, 'Nanoparticles for tendon healing and regeneration: Literature review', Frontiers in Aging Neuroscience, 8, http://dx.doi.org/10.3389/fnagi.2016.00202

Oliver S; Thomas DS; Kavallaris M; Vittorio O; Boyer C, 2016, 'Efficient functionalisation of dextran-aldehyde with catechin: potential applications in the treatment of cancer', Polymer Chemistry, http://dx.doi.org/10.1039/C6PY00228E

Oliver S; Vittorio O; Cirillo G; Boyer C, 2016, 'Enhancing the therapeutic effects of polyphenols with macromolecules', POLYMER CHEMISTRY, 7, pp. 1529 - 1544, http://dx.doi.org/10.1039/c5py01912e

Castro Nava A; Cojoc M; Peitzsch C; Cirillo G; Kurth I; Fuessel S; Erdmann K; Kunhardt D; Vittorio O; Hampel S; Dubrovska A, 2015, 'Development of novel radiochemotherapy approaches targeting prostate tumor progenitor cells using nanohybrids', International Journal of Cancer, 137, pp. 2492 - 2503, http://dx.doi.org/10.1002/ijc.29614

Chen Y; Cass SL; Kutty SK; Yee EMH; Chan DSH; Gardner CR; Vittorio O; Pasquier E; Black DSC; Kumar N, 2015, 'Synthesis, biological evaluation and structure-activity relationship studies of isoflavene based Mannich bases with potent anti-cancer activity', Bioorganic and Medicinal Chemistry Letters, 25, pp. 5377 - 5383, http://dx.doi.org/10.1016/j.bmcl.2015.09.027

Kurniawansyah F; Duong HTT; Luu TD; Mammucari R; Vittorio O; Boyer C; Foster N, 2015, 'Inhalable curcumin formulations: Micronization and bioassay', CHEMICAL ENGINEERING JOURNAL, 279, pp. 799 - 808, http://dx.doi.org/10.1016/j.cej.2015.05.087

Spizzirri UG; Curcio M; Cirillo G; Spataro T; Vittorio O; Picci N; Hampel S; Iemma F; Nicoletta FP, 2015, 'Recent advances in the synthesis and biomedical applications of nanocomposite hydrogels', Pharmaceutics, 7, pp. 413 - 437, http://dx.doi.org/10.3390/pharmaceutics7040413

Spizzirri UG; Hampel S; Cirillo G; Mauro MV; Vittorio O; Cavalcanti P; Giraldi C; Curcio M; Picci N; Iemma F, 2015, 'Functional Gelatin-Carbon Nanotubes Nanohybrids With Enhanced Antibacterial Activity', International Journal of Polymeric Materials and Polymeric Biomaterials, 64, pp. 439 - 447, http://dx.doi.org/10.1080/00914037.2014.958833

Makharza S; Vittorio O; Cirillo G; Oswald S; Hinde E; Kavallaris M; Büchner B; Mertig M; Hampel S, 2015, 'Graphene oxide - Gelatin nanohybrids as functional tools for enhanced carboplatin activity in neuroblastoma cells', Pharmaceutical Research, 32, pp. 2132 - 2143, http://dx.doi.org/10.1007/s11095-014-1604-z

Curcio M; Cirillo G; Vittorio O; Spizzirri UG; Iemma F; Picci N, 2015, 'Hydrolyzed gelatin-based polymersomes as delivery devices of anticancer drugs', European Polymer Journal, 67, pp. 304 - 313, http://dx.doi.org/10.1016/j.eurpolymj.2015.03.058

Syed F; Riggio C; Masini M; Bugliani M; Battaglia V; Novelli M; Suleiman M; Vittorio O; Boggi U; Filipponi F; Marselli L; Bartolozzi C; Masiello P; Raffa V; Marchetti P, 2015, 'Labeling and tracking of human pancreatic islets using carbon nanotubes', Journal of Biomedical Nanotechnology, 11, pp. 730 - 738, http://dx.doi.org/10.1166/jbn.2015.1952

Curcio M; Spizzirri UG; Cirillo G; Vittorio O; Picci N; Nicoletta FP; Iemma F; Hampel S, 2015, 'On demand delivery of ionic drugs from electro-responsive CNT hybrid films', Rsc Advances, 5, pp. 44902 - 44911, http://dx.doi.org/10.1039/c5ra05484b

Meucci S; Vittorio O; Beltram F; Cecchini M, 2014, 'Tubeless biochip for tailoring cell co-cultures in closed microchambers', Microelectronic Engineering, 124, pp. 8 - 12, http://dx.doi.org/10.1016/j.mee.2014.04.015

Antonini S; Cappelluti MA; Meucci S; Jacchetti E; Vittorio O; Parchi P; Lisanti M; Pacini S; Petrini M; Beltram F; Cecchini M, 2014, 'Human mesenchymal stromal cell enhanced morphological polarization by contact interaction with polyethylene terephthalate nanogratings', Current Nanoscience, 10, pp. 773 - 778, http://dx.doi.org/10.2174/1573413710666140815205825

Vittorio O; Voliani V; Faraci P; Karmakar B; Iemma F; Hampel S; Kavallaris M; Cirillo G, 2014, 'Magnetic catechin-dextran conjugate as targeted therapeutic for pancreatic tumour cells', Journal of Drug Targeting, 22, pp. 408 - 415, http://dx.doi.org/10.3109/1061186X.2013.878941

Vittorio O; Brandl M; Cirillo G; Spizzirri UG; Picci N; Kavallaris M; Iemma F; Hampel S, 2014, 'Novel functional cisplatin carrier based on carbon nanotubes-quercetin nanohybrid induces synergistic anticancer activity against neuroblastoma in vitro', Rsc Advances, 4, pp. 31378 - 31384, http://dx.doi.org/10.1039/c4ra03331k

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