By Associate Professor Tao Liu

Journal articles

Ho N; Peng H; Mayoh C; Liu PY; Atmadibrata B; Marshall GM; Li J; Liu T, 2018, 'Delineation of the frequency and boundary of chromosomal copy number variations in paediatric neuroblastoma', Cell Cycle, 17, pp. 749 - 758, http://dx.doi.org/10.1080/15384101.2017.1421875

Bi L; Xie C; Yao M; Thae Hnit SS; Vignarajan S; Wang Y; Wang Q; Xi Z; Xu H; Li Z; de Souza P; Tee A; Wong M; Liu T; Zhao X; Zhou J; Xu L; Dong Q, 2018, 'The histone chaperone complex FACT promotes proliferative switch of G0 cancer cells', International Journal of Cancer, 145, pp. 164 - 178, http://dx.doi.org/10.1002/ijc.32065

Qiu S; Liu PY; Liu T, 2017, 'Up-regulation of LYAR blocks Myc-induced cell death', Cell Cycle, 16, pp. 1857 - 1858, http://dx.doi.org/10.1080/15384101.2017.1374682

Melaiu O; Mina M; Chierici M; Boldrini R; Jurman G; Romania P; D'Alicandro V; Benedetti MC; Castellano A; Liu T; Furlanello C; Locatelli F; Fruci D, 2017, 'PD-L1 is a therapeutic target of the bromodomain inhibitor JQ1 and, combined with HLA class I, a promising prognostic biomarker in neuroblastoma', Clinical Cancer Research, 23, pp. 4462 - 4472, http://dx.doi.org/10.1158/1078-0432.CCR-16-2601

Wong M; Tee AEL; Milazzo G; Bell JL; Poulos RC; Atmadibrata B; Sun Y; Jing D; Ho N; Ling D; Liu PY; Zhang XD; Hüttelmaier S; Wong JWH; Wang J; Polly P; Perini G; Scarlett CJ; Liu T, 2017, 'The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription', Cancer Research, 77, pp. 2522 - 2533, http://dx.doi.org/10.1158/0008-5472.CAN-16-1663

Tang Y; Cheung BB; Atmadibrata B; Marshall GM; Dinger ME; Liu PY; Liu T, 2017, 'The regulatory role of long noncoding RNAs in cancer', Cancer Letters, 391, pp. 12 - 19, http://dx.doi.org/10.1016/j.canlet.2017.01.010

Jung MS; Russell AJ; Liu B; George J; Liu PY; Liu T; DeFazio A; Bowtell DDL; Oberthuer A; London WB; Fletcher JI; Haber M; Norris MD; Henderson MJ, 2017, 'A Myc activity signature predicts poor clinical outcomes in Myc-associated cancers', Cancer Research, 77, pp. 971 - 981, http://dx.doi.org/10.1158/0008-5472.CAN-15-2906

Peng H; Lan C; Liu Y; Liu T; Blumenstein M; Li J, 2017, 'Chromosome preference of disease genes and vectorization for the prediction of non-coding disease genes', Oncotarget, 8, pp. 78901 - 78916, http://dx.doi.org/10.18632/oncotarget.20481

Sun Y; Atmadibrata B; Yu D; Wong M; Liu B; Ho N; Ling D; Tee AE; Wang J; Mungrue IN; Liu PY; Liu T, 2017, 'Upregulation of LYAR induces neuroblastoma cell proliferation and survival', Cell Death and Differentiation, 24, pp. 1645 - 1654, http://dx.doi.org/10.1038/cdd.2017.98

Liu T; Yin H, 2017, 'PDK1 promotes tumor cell proliferation and migration by enhancing the Warburg effect in non-small cell lung cancer', ONCOLOGY REPORTS, 37, pp. 193 - 200, http://dx.doi.org/10.3892/or.2016.5253

Liu T; Kiwak E; Tinetti ME, 2017, 'Perceptions of Hospital-Dependent Patients on Their Needs for Hospitalization', JOURNAL OF HOSPITAL MEDICINE, 12, pp. 450 - 453, http://dx.doi.org/10.12788/jhm.2756

Yin H-L; Yin S-Q; Lin Q-Y; Xu Y; Xu H-W; Liu T, 2017, 'Prevalence of comorbidities in chronic obstructive pulmonary disease patients A meta-analysis', MEDICINE, 96, http://dx.doi.org/10.1097/MD.0000000000006836

Liu PY; Atmadibrata B; Mondal S; Tee AE; Liu T, 2016, 'NCYM is upregulated by lncUSMycN and modulates N-Myc expression', International Journal of Oncology, 49, pp. 2464 - 2470, http://dx.doi.org/10.3892/ijo.2016.3730

Lynch JR; Yi H; Casolari DA; Voli F; Gonzales-Aloy E; Fung TK; Liu B; Brown A; Liu T; Haber M; Norris MD; Lewis ID; So CWE; D'Andrea RJ; Wang JY, 2016, 'Gaq signaling is required for the maintenance of MLL-AF9-induced acute myeloid leukemia', Leukemia, 30, pp. 1745 - 1748, http://dx.doi.org/10.1038/leu.2016.24

Guo ST; Chi MN; Yang RH; Guo XY; Zan LK; Wang CY; Xi YF; Jin L; Croft A; Tseng HY; Yan XG; Farrelly M; Wang FH; Lai F; Wang JF; Li YP; Ackland S; Scott R; Agoulnik IU; Hondermarck H; Thorne RF; Liu T; Zhang XD; Jiang CC, 2016, 'INPP4B is an oncogenic regulator in human colon cancer', Oncogene, 35, pp. 3049 - 3061, http://dx.doi.org/10.1038/onc.2015.361

Xi Z; Yao M; Li Y; Xie C; Holst J; Liu T; Cai S; Lao Y; Tan H; Xu HX; Dong Q, 2016, 'Guttiferone K impedes cell cycle re-entry of quiescent prostate cancer cells via stabilization of FBXW7 and subsequent c-MYC degradation', Cell Death and Disease, 7, pp. e2252 - e2252, http://dx.doi.org/10.1038/cddis.2016.123

Shahbazi J; Liu PY; Atmadibrata B; Bradner JE; Marshall GM; Lock RB; Liu T, 2016, 'The bromodomain inhibitor jq1 and the histone deacetylase inhibitor panobinostat synergistically reduce n-myc expression and induce anticancer effects', Clinical Cancer Research, 22, pp. 2534 - 2544, http://dx.doi.org/10.1158/1078-0432.CCR-15-1666

Kim PY; Tan O; Liu B; Trahair T; Liu T; Haber M; Norris MD; Marshall GM; Cheung BB, 2016, 'High TDP43 expression is required for TRIM16-induced inhibition of cancer cell growth and correlated with good prognosis of neuroblastoma and breast cancer patients', Cancer Letters, 374, pp. 315 - 323, http://dx.doi.org/10.1016/j.canlet.2016.02.021

Xue C; Yu DMT; Gherardi S; Koach J; Milazzo G; Gamble L; Liu B; Valli E; Russell AJ; London WB; Liu T; Cheung BB; Marshall GM; Perini G; Haber M; Norris MD, 2016, 'MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4', Oncotarget, 7, pp. 54937 - 54951, http://dx.doi.org/10.18632/oncotarget.10709

Liu PY; Sokolowski N; Guo ST; Siddiqi F; Atmadibrata B; Telfer TJ; Sun Y; Zhang L; Yu D; Mccarroll J; Liu B; Yang RH; Guo XY; Tee AE; Itoh K; Wang J; Kavallaris M; Haber M; Norris MD; Cheung BB; Byrne JA; Ziegler DS; Marshall GM; Dinger ME; Codd R; Zhang XD; Liu T, 2016, 'The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs', Oncotarget, 7, pp. 79217 - 79232, http://dx.doi.org/10.18632/oncotarget.12640

Tee AE; Liu B; Song R; Li J; Pasquier E; Cheung BB; Jiang C; Marshall GM; Haber M; Norris MD; Fletcher JI; Dinger ME; Liu T, 2016, 'The long noncoding RNA MALAT1 promotes tumor-driven angiogenesis by up-regulating pro-angiogenic gene expression', Oncotarget, 7, pp. 8663 - 8675, http://dx.doi.org/10.18632/oncotarget.6675

Sun Y; Bell JL; Carter D; Gherardi S; Poulos RC; Milazzo G; Wong JWH; Al-Awar R; Tee AE; Liu PY; Liu B; Atmadibrata B; Wong M; Trahair T; Zhao Q; Shohet JM; Haupt Y; Schulte JH; Brown PJ; Arrowsmith CH; Vedadi M; MacKenzie KL; Hüttelmaier S; Perini G; Marshall GM; Braithwaite A; Liu T, 2015, 'WDR5 supports an N-myc transcriptional complex that drives a protumorigenic gene expression signature in neuroblastoma', Cancer Research, 75, pp. 5143 - 5154, http://dx.doi.org/10.1158/0008-5472.CAN-15-0423

Carter DR; Murray J; Cheung BB; Gamble L; Koach J; Tsang J; Sutton S; Kalla H; Syed S; Gifford AJ; Issaeva N; Biktasova A; Atmadibrata B; Sun Y; Sokolowski N; Ling D; Kim PY; Webber H; Clark A; Ruhle M; Liu B; Oberthuer A; Fischer M; Byrne J; Saletta F; Thwe LM; Purmal A; Haderski G; Burkhart C; Speleman F; De Preter K; Beckers A; Ziegler DS; Liu T; Gurova KV; Gudkov AV; Norris MD; Haber M; Marshall GM, 2015, 'Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma', Science Translational Medicine, 7, pp. 312ra176, http://dx.doi.org/10.1126/scitranslmed.aab1803

Cheung BB; Tan O; Koach J; Liu B; Shum MSY; Carter DR; Sutton S; Po'uha ST; Chesler L; Haber M; Norris MD; Kavallaris M; Liu T; O'Neill GM; Marshall GM, 2015, 'Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma', Molecular Oncology, 9, pp. 1484 - 1500, http://dx.doi.org/10.1016/j.molonc.2015.04.005

Bell JL; Turlapati R; Liu T; Schulte JH; Hüttelmaier S, 2015, 'IGF2BP1 harbors prognostic significance by gene gain and diverse expression in neuroblastoma', Journal of Clinical Oncology, 33, pp. 1285 - 1293, http://dx.doi.org/10.1200/JCO.2014.55.9880

Song R; Liu Q; Liu T; Li J, 2015, 'Connecting rules from paired miRNA and mRNA expression data sets of HCV patients to detect both inverse and positive regulatory relationships', BMC Genomics, 16, pp. s11, http://dx.doi.org/10.1186/1471-2164-16-S2-S11

Liu PY; Erriquez D; Marshall GM; Tee AE; Polly P; Wong M; Liu B; Bell JL; Zhang XD; Milazzo G; Cheung BB; Fox A; Swarbrick A; Hüttelmaier S; Kavallaris M; Perini G; Mattick JS; Dinger ME; Liu T, 2015, 'Erratum: Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression (Journal of the National Cancer Institute (2014) 106:7 (dju113) DOI: 10.1093/jnci/dju113)', Journal of the National Cancer Institute, 107, http://dx.doi.org/10.1093/jnci/dju359

Chi MN; Guo ST; Wilmott JS; Guo XY; Yan XG; Wang CY; Liu XY; Jin L; Tseng HY; Liu T; Croft A; Hondermarck H; Scolyer RA; Jiang CC; Zhang XD, 2015, 'INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas', Oncotarget, 6, pp. 39891 - 39907, http://dx.doi.org/10.18632/oncotarget.5359

Manchanda R; Loggenberg K; Sanderson S; Burnell M; Wardle J; Gessler S; Side L; Balogun N; Desai R; Kumar A; Dorkins H; Wallis Y; Chapman C; Taylor R; Jacobs C; Tomlinson I; McGuire A; Beller U; Menon U; Jacobs I, 2015, 'Population testing for cancer predisposing BRCA1/BRCA2 mutations in the ashkenazi-jewish community: A randomized controlled trial', Journal of the National Cancer Institute, 107, http://dx.doi.org/10.1093/jnci/dju379

Wong M; Polly P; Liu T, 2015, 'The histone methyltransferase DOT1L: Regulatory functions and a cancer therapy target', American Journal of Cancer Research, 5, pp. 2823 - 2837

Yang C; Zheng S; Liu Q; Liu T; Lu M; Dai F; Gao X; Sheyhidin I; Lu X, 2015, 'Metadherin is required for the proliferation, migration, and invasion of esophageal squamous cell carcinoma and its meta-analysis', TRANSLATIONAL RESEARCH, 166, pp. 614 - 626, http://dx.doi.org/10.1016/j.trsl.2015.05.004

Liu PY; Erriquez D; Marshall GM; Tee AE; Polly P; Wong M; Liu B; Bell JL; Zhang XD; Milazzo G; Cheung BB; Fox A; Swarbrick A; Hüttelmaier S; Kavallaris M; Perini G; Mattick JS; Dinger ME; Liu T, 2014, 'Effects of a Novel Long Noncoding RNA, lncUSMycN, on N-Myc Expression and Neuroblastoma Progression', Journal of the National Cancer Institute, 106, pp. dju113, http://dx.doi.org/10.1093/jnci/dju113

Atmadibrata B; Liu PY; Sokolowski N; Zhang L; Wong M; Tee AE; Marshall GM; Liu T, 2014, 'The novel long noncoding RNA linc00467 promotes cell survival but is down-regulated by N-Myc', PLoS ONE, 9, pp. e88112, http://dx.doi.org/10.1371/journal.pone.0088112

Tee EL; Ling D; Nelson C; Atmadibrata B; Dinger M; XU N; Mizukami T; Liu PY; Liu B; Cheung B; Pasquier E; Haber M; Norris MD; Suzuki T; Marshall GM; Liu T, 2014, 'The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1', Oncotarget, 5, pp. 1793 - 1804, http://dx.doi.org/10.18632/oncotarget.1785

Kim PY; Tan O; Diakiw SM; Carter D; Sekerye EO; Wasinger VC; Liu T; Kavallaris M; Norris MD; Haber M; Chesler L; Dolnikov A; Trahair TN; Cheung NK; Marshall GM; Cheung BB; Sekyere E, 2014, 'Identification of plasma Complement C3 as a potential biomarker for neuroblastoma using a quantitative proteomic approach', Journal of Proteomics, 96, pp. 1 - 12, http://dx.doi.org/10.1016/j.jprot.2013.10.032

Shahbazi J; Scarlett CJ; Norris MD; Liu B; Haber M; Tee AE; Carrier A; Biankin AV; London WB; Marshall GM; Lock RB; Liu T, 2014, 'Histone Deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1', Oncotarget, 5, pp. 4257 - 4268, http://dx.doi.org/10.18632/oncotarget.1991

Zhang L; Sokolowski N; Atmadibrata B; Liu T, 2014, 'Histone demethylase JARID1B promotes cell proliferation but is downregulated by N-Myc oncoprotein', Oncology Reports, 31, pp. 1935 - 1939, http://dx.doi.org/10.3892/or.2014.3006

Vignarajan S; Xie C; Yao M; Sun Y; Simanainen U; Sved P; Liu T; Dong Q, 2014, 'Loss of PTEN stabilizes the lipid modifying enzyme cytosolic phospholipase A2a via AKT in prostate cancer cells', Oncotarget, 5, pp. 6289 - 6299, http://dx.doi.org/10.18632/oncotarget.2198

Marshall GM; Carter DR; Cheung BB; Liu T; Mateos MK; Meyerowitz JG; Weiss WA, 2014, 'The prenatal origins of cancer', Nature Reviews Cancer, 14, pp. 277 - 289, http://dx.doi.org/10.1038/nrc3679

Sutton SK; Koach J; Tan O; Liu B; Carter DR; Wilmott JS; Yosufi B; Haydu LE; Mann GJ; Thompson JF; Long GV; Liu T; McArthur G; Zhang XD; Scolyer RA; Cheung BB; Marshall GM, 2014, 'TRIM16 inhibits proliferation and migration through regulation of interferon beta 1 in melanoma cells', Oncotarget, 5, pp. 10127 - 10139, http://dx.doi.org/10.18632/oncotarget.2466

Lai F; Guo ST; Jin L; Jiang CC; Wang CY; Croft A; Chi MN; Tseng HY; Farrelly M; Atmadibrata B; Norman J; Liu T; Hersey P; Zhang XD, 2013, 'Cotargeting histone deacetylases and oncogenic BRAF synergistically kills human melanoma cells by necrosis independently of RIPK1 and RIPK3', Cell Death and Disease, 4, pp. e655 - e655, http://dx.doi.org/10.1038/cddis.2013.192

Sekyere E; Thomas WD; Keating J; Calao M; Cui HJ; Chen JB; Raif A; Jankowski K; Cheung B; Davies NP NP; Trahair TN; Liu T; Wainwright BJ; Ding HF; Marshall GM; Haber M; Norris M; Tan O; Chen B; van Bekkum M, 2013, 'Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation', Oncogene, 32, pp. 3616 - 3626, http://dx.doi.org/10.1038/onc.2012.368

Malyukova A; Papa R; O'Brien R; Giles JE; Trahair TN; Pozza LD; Sutton R; Liu T; Haber M; Norris MD; Lock RB; Marshall GM; Giles J, 2013, 'FBXW7 regulates glucocorticoid response in T-cell acute lymphoblastic leukaemia by targeting the glucocorticoid receptor for degradation', Leukemia, 27, pp. 1053 - 1062, http://dx.doi.org/10.1038/leu.2012.361

Sun YT; Liu PY; Scarlett CJ; Malyukova A; Liu B; Mackenzie KL; Biankin AV; Liu T; Marshall G, 2013, 'Histone deacetylase 5 blocks neuroblastoma cell differentiation by interacting with N-Myc', Oncogene, 33, pp. 2987 - 2994, http://dx.doi.org/10.1038/onc.2013.253

Ye Y; Jin L; Wilmott J; Hu WL; Yosufi B; Thorne RF; Liu T; Rizos H; Yan XG; Dong L; Tay KH; Tseng HT; Guo ST; De Bock CE; Jiang CC; Wang CY; Wu M; Zhang LJ; Hersey P; Scolyer RA; Zhang XD, 2013, 'PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma', Nature communications, 4, pp. Article number 1508, http://dx.doi.org/10.1038/ncomms2489

Wauters E; Sanchez-Arevalo Lobo VJ; Pinho AV; Mawson A; Herranz D; Wu J; Cowley MJ; Colvin EK; Njicop EN; Sutherland RL; Liu T; Serrano M; Bouwens L; Real FX; Biankin AV; Rooman I; Mawson A, 2013, 'Sirtuin-1 regulates acinar to ductal metaplasia and supports cancer cell viability in pancreatic cancer', Cancer research, 73, pp. 2357 - 2367, http://dx.doi.org/10.1158/0008-5472.CAN-12-3359

Liu PY; Xu N; Malyukova A; Scarlett CJ; Sun YT; Zhang XD; Ling D; Su SP; Nelson CA; Chang DK; Koach J; Tee AE; Haber M; Norris MD; Rooman I; Toon C; Xue C; Cheung B; Kumar S; Marshall GM; Biankin AV; Liu T; Shih-Ping Su J; Toon CCW, 2013, 'The histone deacetylase SIRT2 stabilizes Myc oncoproteins', Cell Death and Differentiation, 20, pp. 503 - 514, http://dx.doi.org/10.1038/cdd.2012.147

Shahbazi J; Lock RB; Liu T, 2013, 'Tumor protein 53-induced nuclear protein 1 enhances p53 function and represses tumorigenesis', Frontiers in Genetics, 13, pp. Art. No. 80, http://dx.doi.org/10.3389/fgene.2013.00080

Kan C; Petti C; Bracken L; Maritz M; Xu N; O'Brien R; Yang C; Liu T; Yuan J; Lock RB; Mackenzie KL, 2013, 'Up-regulation of survivin during immortalization of human myofibroblasts is linked to repression of tumor suppressor p16(INK4a) protein and confers resistance to oxidative stress', The Journal of Biological Chemistry, 288, pp. 12032 - 12041, http://dx.doi.org/10.1074/jbc.M112.447821

Petti C; Kan C-Y; Dietrich PA; Lauryn B; Xu N; Yuan J; Liu T; MacKenzie KL, 2012, 'Upregulation of survivin during immortalization is linked to repression of p16INK4a and confers resistance to oxidative stress', CANCER RESEARCH, 72, http://dx.doi.org/10.1158/1538-7445.AM2012-2196

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