Select Publications
Journal articles
2009, 'The cyclin-dependent kinase inhibitor, p21WAF1, promotes angiogenesis by repressing gene transcription of thioredoxin-binding protein 2 in cancer cells', Carcinogenesis, 30, pp. 1865 - 1871, http://dx.doi.org/10.1093/carcin/bgp225
,2007, 'Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis (Proceedings of the National Academy of Science of the United States of America (November 20, 2007) 104; 47, (18682-18687) DOI: 10.1073/pnas.0705524104)', Proceedings of the National Academy of Sciences of the United States of America, 104, pp. 21021, http://dx.doi.org/10.1073/pnas.0711060105
,2007, 'Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis (vol 104, pg 18682, 2007)', PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 104, pp. 21021 - 21021, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000252077400076&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2007, 'Erratum: Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis (Proceedings of the National Academy of Sciences of the United States of America (2007) 104 (18682-18687) DOI: 10.1073/pnas.0705524104)', Proceedings of the National Academy of Sciences of the United States of America, 120, http://dx.doi.org/10.1073/pnas.2220015120
,2007, 'Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis', Proceedings of the National Academy of Sciences of the United States of America, 104, pp. 18682 - 18687, http://dx.doi.org/10.1073/pnas.0705524104
,2007, 'Enhancing the anti-angiogenic action of histone deacetylase inhibitors', Molecular Cancer, 6, pp. 68 - 79, http://dx.doi.org/10.1186/1476-4598-6-68
,2006, 'Histone deacetylase inhibitors: multifunctional anticancer agents', Cancer Treatment Reviews, 32, pp. 157 - 165, http://dx.doi.org/10.1016/j.ctrv.2005.12.006
,2005, 'The propeptide mediates formation of stromal stores of ProMIC-1: role in determining prostate cancer outcome', Cancer Research, 65, pp. 2330 - 2336, http://dx.doi.org/10.1158/0008-5472.CAN-04-3827
,2005, 'The retinoid anticancer signal: mechanisms of target gene regulation', British Journal of Cancer, 93, pp. 310 - 318, http://dx.doi.org/10.1038/sj.bjc.6602700
,2003, 'Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum', Proceedings of the National Academy of Sciences of the United States of America, 100, pp. 3410 - 3415, http://dx.doi.org/10.1073/pnas.0530278100
,2003, 'Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells', Cancer research, 63, pp. 5034 - 5040
,2003, 'MIC 1 serum level and genotype: Associations with progress and prognosis of colorectal carcinoma', Clinical Cancer Research, 9, pp. 2642 - 2650
,2002, 'Antibody-based approach to high-volume genotyping for MIC-1 polymorphism', BioTechniques, 33, pp. 118 - 120
,2002, 'Concentration in plasma of macrophage inhibitory cytokine-1 and risk of cardiovascular events in women: a nested case-control study', Lancet, 359, pp. 2159 - 2163, http://dx.doi.org/10.1016/S0140-6736(02)09093-1
,2000, 'ATP P2X receptors play little role in the maintenance of neuropathic hyperalgesia', Neuroreport, 11, pp. 1272 - 1669
,2000, 'Depletion of macrophages reduces axonal degeneration and hyperalgesia following nerve injury', Pain, pp. 25 - 32
,2000, 'Hyperalgesia due to nerve injury - role of peroxynitrite', Neuroscience, pp. 125 - 131
,1999, 'Zinc alleviates thermal hyperalgesia due to partial nerve injury', NeuroReport, 10, pp. 645 - 649, http://dx.doi.org/10.1097/00001756-199902250-00037
,1999, 'Free radicals contribute to the reduction in peripheral vascular responses and the maintenance of thermal hyperalgesia in rats with chronic constriction injury', Pain, 79, pp. 31 - 37, http://dx.doi.org/10.1016/S0304-3959(98)00143-2
,1999, 'Zinc alleviates thermal hyperalgesia due to partial nerve injury', Neuroreport, 10, pp. 1619 - 1623
,Conference Papers
2022, 'The novel long noncoding RNA lncNeur promotes neuroblastoma by up-regulating AURKA and Myc expression', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, LA, New Orleans, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), LA, New Orleans, 08 April 2022 - 13 April 2022, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000892509503474&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2022, 'The novel long noncoding RNA lncNeur promotes neuroblastoma by up-regulating AURKA and Myc expression.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, LA, New Orleans, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), LA, New Orleans, 08 April 2022 - 13 April 2022, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000892509501411&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2020, 'The super-enhancer driven long noncoding RNA lncNB promotes neuroblastoma tumorigenesis', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, ELECTR NETWORK, presented at AACR Annual Meeting, ELECTR NETWORK, 22 June 2020 - 24 June 2020, http://dx.doi.org/10.1158/1538-7445.AM2020-5721
,2019, 'MILIP is a pan cancer-associated long noncoding RNA that links MYC to inactivation of p53', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, GA, Atlanta, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), GA, Atlanta, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-4504
,2018, 'Eradication of neuroblastoma by suppressing the expression of a single noncoding RNA', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, IL, Chicago, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), IL, Chicago, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-2453
,2016, 'IDENTIFICATION OF A NOVEL TRANSCRIPTION FACTOR COMPLEX IN CLASS I HDACS-MEDIATED UPREGULATION OF PD-L1 IN CANCER CELLS', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 24 - 25, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000387772400049&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2016, 'Eradication of neuroblastoma by suppressing the expression of a single long noncoding RNA', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, LA, New Orleans, presented at AACR 107th Annual Meeting on Bioinformatics and Systems Biology, LA, New Orleans, 16 April 2016 - 20 April 2016, http://dx.doi.org/10.1158/1538-7445.AM2016-2664
,2016, 'MYCN and TFAP4 promote neuroblastoma malignancy by cooperating in the regulation a subset of target genes involved in cancer cell growth and metastasis', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, LA, New Orleans, presented at 107th Annual Meeting of the American-Association-of-Cancer-Research (AACR), LA, New Orleans, 16 April 2016 - 20 April 2016, http://dx.doi.org/10.1158/1538-7445.AM2016-2450
,2015, 'Inositol polyphosphate 4-phosphatase II activates PI3K/SGK3 signaling to promote proliferation of human melanoma cells', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-4718
,2015, 'PA2G4 predicts poor prognosis in neuroblastoma patients and promotes neuroblastoma progression by enhancing MYCN protein stability', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-962
,2015, 'MYCN and is a therapeutic target in neuroblastoma', in MOLECULAR CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, La Jolla, presented at AACR Special Conference on Myc - From Biology to Therapy, CA, La Jolla, 07 January 2015 - 10 January 2015, http://dx.doi.org/10.1158/1557-3125,MYC15-PRO9
,2014, 'INOSITOL POLYPHOSPHATE 4-PHOSPHATASE II PROMOTES PI3K SIGNALING AND FUNCTIONS AS AN ONCOGENIC REGULATOR IN HUMAN COLON CANCER', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 18 - 19, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000346344100047&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2014, 'IGF2BP1 and MYCN cooperate in an oncogenic feedback loop, in high-risk neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, San Diego, presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-3103
,2014, 'The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, San Diego, presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-5005
,2014, 'The histone methyltransferase adaptor WDR5 is a novel cofactor in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, San Diego, presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-1378
,2013, 'BET bromodomain inhibition as a therapeutic strategy to target N-Myc in neuroblastoma', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, NETHERLANDS, Amsterdam, pp. S356 - S356, presented at European Cancer Congress 2013 - 17th ECCO / 38th ESMO / 32nd ESTRO, NETHERLANDS, Amsterdam, 27 September 2013 - 01 October 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000326843602301&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2013, 'Linc367, a novel long intergenic noncoding RNA, up-regulates N-Myc gene expression and neuroblastoma cell proliferation', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, NETHERLANDS, Amsterdam, pp. S356 - S356, presented at European Cancer Congress 2013 - 17th ECCO / 38th ESMO / 32nd ESTRO, NETHERLANDS, Amsterdam, 27 September 2013 - 01 October 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000326843602302&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2013, 'The facilitates chromatin transcription (FACT) protein complex promotes neuroblastoma tumor initiation.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-5043
,2013, 'TRIM16 is a prognostic marker for patients with lymph node metastatic melanoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-3876
,2012, 'PP2A signaling is overridden by MEK/ERK activity leading to suppression of Bim and protection of melanoma cells from ER stress-induced apoptosis', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM2012-4990
,2010, 'Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM10-4869
,2009, 'The role of N-Myc-induced HDAC2 over-expression in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209701802056&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2008, 'Full-length tissue transglutaminase is a resistance factor for cell differentiation in neuroblastoma', in EJC SUPPLEMENTS, PERGAMON-ELSEVIER SCIENCE LTD, FRANCE, Lyon, pp. 94 - 94, presented at 20th Meeting of the European-Association-for-Cancer-Research, FRANCE, Lyon, 05 July 2008 - 08 July 2008, http://dx.doi.org/10.1016/S1359-6349(08)71539-8
,2006, 'MYCN interacts with histone deacetylase to modulate target gene transcription', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454608802468&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,Conference Presentations
2014, 'Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1', presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-5138
,2014, 'TRIM16 inhibits cell growth through direct interaction and modulation of TDP43 protein stability in cancer cells', presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-1403
,2014, 'Histone deacetylase 5 blocks neuroblastoma cell differentiation by forming a protein complex with N-Myc and repressing target gene transcription', https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000341276000510&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,Conference Abstracts
2019, 'Abstract 5209: Efficacious targeting of TERT oncogene rearrangement with BET bromodomain inhibitor and proteasome inhibitor combination therapy', in Molecular and Cellular Biology / Genetics, American Association for Cancer Research, pp. 5209 - 5209, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-5209
,2019, 'Alyref is a novel binding partner and co-factor for MYCN-driven oncogenesis in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, GA, Atlanta, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), GA, Atlanta, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-3659
,2019, 'Efficacious targeting of TERT oncogene rearrangement with BET bromodomain inhibitor and proteasome inhibitor combination therapy', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, GA, Atlanta, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), GA, Atlanta, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-5209
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