By Dr Alvin Kamili

Journal articles

Poltavets V; Jung M; Skhinas J; Kimpton K; Kamili A; Tax G; Mao J; Cui L; Wong M; Cowley MJ; Lau L; Dolman EME; Gooding JJ; Kavallaris M, 2024, 'Abstract 5475: Development of high-throughput 3D bioprinted pediatric models for precision medicine', Cancer Research, 84, pp. 5475 - 5475, http://dx.doi.org/10.1158/1538-7445.am2024-5475

Mayoh C; Mao J; Xie J; Tax G; Chow SO; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; M Dolman ME, 2023, 'High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer', Cancer Research, 83, pp. 2716 - 2732, http://dx.doi.org/10.1158/0008-5472.CAN-22-3702

Hastings JF; Latham SL; Kamili A; Wheatley MS; Han JZR; Wong-Erasmus M; Phimmachanh M; Nobis M; Pantarelli C; Cadell AL; O’Donnell YEI; Leong KH; Lynn S; Geng FS; Cui L; Yan S; Achinger-Kawecka J; Stirzaker C; Norris MD; Haber M; Trahair TN; Speleman F; De Preter K; Cowley MJ; Bogdanovic O; Timpson P; Cox TR; Kolch W; Fletcher JI; Fey D; Croucher DR, 2023, 'Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma', Science Advances, 9, http://dx.doi.org/10.1126/sciadv.abp8314

Lau LMS; Mayoh C; Xie J; Barahona P; MacKenzie KL; Wong M; Kamili A; Tsoli M; Failes TW; Kumar A; Mould EVA; Gifford A; Chow SO; Pinese M; Fletcher JI; Arndt GM; Khuong-Quang DA; Wadham C; Batey D; Eden G; Trebilcock P; Joshi S; Alfred S; Gopalakrishnan A; Khan A; Grebert Wade D; Strong PA; Manouvrier E; Morgan LT; Span M; Lim JY; Cadiz R; Ung C; Thomas DM; Tucker KM; Warby M; McCowage GB; Dalla-Pozza L; Byrne JA; Saletta F; Fellowes A; Fox SB; Norris MD; Tyrrell V; Trahair TN; Lock RB; Cowley MJ; Ekert PG; Haber M; Ziegler DS; Marshall GM; Trahair T, 2022, 'In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer', EMBO Molecular Medicine, 14, pp. e14608, http://dx.doi.org/10.15252/emmm.202114608

Gao J; Jung M; Williams RT; Hui D; Russell AJ; Naim AJ; Kamili A; Clifton M; Bongers A; Mayoh C; Ho G; Scott CL; Jessup W; Haber M; Norris MD; Henderson MJ, 2022, 'Suppression of the ABCA1 Cholesterol Transporter Impairs the Growth and Migration of Epithelial Ovarian Cancer', Cancers, 14, pp. 1878, http://dx.doi.org/10.3390/cancers14081878

Holliday H; Yang J; Dodson E; Nikolic I; Kamili A; Wheatley M; Deng N; Alexandrou S; Davis TP; Kavallaris M; Caldon CE; McCarroll J; De Preter K; Mestdagh P; Marshall GM; Simpson KJ; Fletcher J; Swarbrick A, 2022, 'miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastoma', Molecular Therapy, 30, pp. 1119 - 1134, http://dx.doi.org/10.1016/j.ymthe.2022.01.004

Xiao L; Somers K; Murray J; Pandher R; Karsa M; Ronca E; Bongers A; Terry R; Ehteda A; Gamble LD; Issaeva N; Leonova KI; O’Connor A; Mayoh C; Venkat P; Quek H; Brand J; Kusuma FK; Pettitt JA; Mosmann E; Kearns A; Eden G; Alfred S; Allan S; Zhai L; Kamili A; Gifford AJ; Carter DR; Henderson MJ; Fletcher JI; Marshall G; Johnstone RW; Cesare AJ; Ziegler DS; Gudkov AV; Gurova KV; Norris MD; Haber M, 2021, 'Dual targeting of chromatin stability by the curaxin CBL0137 and histone deacetylase inhibitor panobinostat shows significant preclinical efficacy in neuroblastoma', Clinical Cancer Research, 27, pp. 4338 - 4352, http://dx.doi.org/10.1158/1078-0432.CCR-20-2357

Grohmann C; Walker F; Devlin M; Luo MX; Chüeh AC; Doherty J; Vaillant F; Ho GY; Wakefield MJ; Weeden CE; Kamili A; Murray J; Po’uha ST; Weinstock J; Kane SR; Faux MC; Broekhuizen E; Zheng Y; Shield-Artin K; Kershaw NJ; Tan CW; Witchard HM; Ebert G; Charman SA; Street I; Kavallaris M; Haber M; Fletcher JI; Asselin-Labat ML; Scott CL; Visvader JE; Lindeman GJ; Watson KG; Burgess AW; Lessene G, 2021, 'Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors', Cell Death and Disease, 12, pp. 268, http://dx.doi.org/10.1038/s41419-020-03269-0

Chen J; Nelson C; Wong M; Tee AE; Liu PY; La T; Fletcher JI; Kamili A; Mayoh C; Bartenhagen C; Trahair TN; Xu N; Jayatilleke N; Wong M; Peng H; Atmadibrata B; Cheung BB; Lan Q; Bryan TM; Mestdagh P; Vandesompele J; Combaret V; Boeva V; Wang JY; Janoueix-Lerosey I; Cowley MJ; MacKenzie KL; Dolnikov A; Li J; Polly P; Marshall GM; Reddel RR; Norris MD; Haber M; Fischer M; Zhang XD; Pickett HA; Liu T, 2021, 'Targeted therapy of TERT-rearranged neuroblastoma with BET bromodomain inhibitor and proteasome inhibitor combination therapy', Clinical Cancer Research, 27, pp. 1438 - 1451, http://dx.doi.org/10.1158/1078-0432.CCR-20-3044

Xie J; Kumar A; Dolman MEM; Mayoh C; Khuong-Quang DA; Cadiz R; Wong-Erasmus M; Mould EVA; Grebert-Wade D; Barahona P; Kamili A; Tsoli M; Failes TW; Chow SO; Bhatia K; Marshall GM; Ziegler DS; Haber M; Lock RB; Tyrrell V; Lau L; Athanasatos P; Gifford AJ; Arndt G, 2021, 'The important role of routine cytopathology in pediatric precision oncology', Cancer Cytopathology, 129, pp. 805 - 818, http://dx.doi.org/10.1002/cncy.22448

Subhash VV; Huang L; Kamili A; Wong M; Chen D; Venn NC; Atkinson C; Mayoh C; Venkat P; Tyrrell V; Marshall GM; Cowley MJ; Ekert PG; Norris MD; Haber M; Henderson MJ; Sutton R; Fletcher JI; Trahair TN; Vijayasubhash V, 2021, 'Whole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma', British Journal of Cancer, 126, pp. 482 - 491, http://dx.doi.org/10.1038/s41416-021-01538-z

Tee AE; Ciampa OC; Wong M; Fletcher JI; Kamili A; Chen J; Ho N; Sun Y; Carter DR; Cheung BB; Marshall GM; Liu PY; Liu T, 2020, 'Combination therapy with the CDK7 inhibitor and the tyrosine kinase inhibitor exerts synergistic anticancer effects against MYCN-amplified neuroblastoma', International Journal of Cancer, 147, pp. 1928 - 1938, http://dx.doi.org/10.1002/ijc.32936

Gao J; Jung MS; Mayoh C; Venkat P; Hannan KM; Fletcher JI; Kamili A; Gifford AJ; Kusnadi EP; Pearson RB; Hannan RD; Haber M; Norris MD; Somers K; Henderson MJ, 2020, 'Suppression of ABCE1-mediated mRNA translation limits N-MYC-driven cancer progression', Cancer Research, 80, pp. 3706 - 3718, http://dx.doi.org/10.1158/0008-5472.CAN-19-3914

Vittorio O; Kamili A; Valli E; Kavallaris M; LE GRAND M, 2020, 'Interplay between MycN and c-Myc regulates radioresistance and cancer stem cell phenotype in neuroblastoma upon glutamine deprivation', Theranostics, 10, pp. 6411 - 6429, http://dx.doi.org/10.7150/thno.42602

Huynh T; Murray J; Flemming CL; Kamili A; Hofmann U; Cheung L; Roundhill EA; Yu DMT; Webber HT; Schwab M; Henderson MJ; Haber M; Norris MD; Fletcher JI, 2020, 'CCI52 sensitizes tumors to 6-mercaptopurine and inhibits MYCN-amplified tumor growth', Biochemical Pharmacology, 172, pp. 113770, http://dx.doi.org/10.1016/j.bcp.2019.113770

Kamili A; Atkinson C; Trahair TN; Fletcher JI, 2020, 'Mouse models of high-risk neuroblastoma', Cancer and Metastasis Reviews, http://dx.doi.org/10.1007/s10555-020-09855-0

Kamili A; Gifford AJ; Li N; Mayoh C; Chow S-O; Failes TW; Eden GL; Cadiz R; Xie J; Lukeis RE; Norris MD; Haber M; McCowage GB; Arndt GM; Trahair TN; Fletcher JI, 2020, 'Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy', British Journal of Cancer, 122, pp. 680 - 691, http://dx.doi.org/10.1038/s41416-019-0682-4

Gamble LD; Purgato S; Murray J; Xiao L; Yu DMT; Hanssen KM; Giorgi FM; Carter DR; Gifford AJ; Valli E; Milazzo G; Kamili A; Mayoh C; Liu B; Eden G; Sarraf S; Allan S; Giacomo SD; Flemming CL; Russell AJ; Cheung BB; Oberthuer A; London WB; Fischer M; Trahair TN; Fletcher JI; Marshall GM; Ziegler DS; Hogarty MD; Burns MR; Perini G; Norris MD; Haber M, 2019, 'Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma', Science Translational Medicine, 11, http://dx.doi.org/10.1126/scitranslmed.aau1099

Kamili A; Roslan N; Frost S; Cantrill LC; Wang D; Della-Franca A; Bright RK; Groblewski GE; Straub BK; Hoy AJ; Chen Y; Byrne JA, 2015, 'TPD52 expression increases neutral lipid storage within cultured cells', Journal of Cell Science, 128, pp. 3223 - 3238, http://dx.doi.org/10.1242/jcs.167692

Chen Y; Kamili A; Hardy JR; Groblewski GE; Khanna KK; Byrne JA, 2013, 'Tumor protein D52 represents a negative regulator of ATM protein levels', Cell Cycle, 12, pp. 3083 - 3097, http://dx.doi.org/10.4161/cc.26146

Chung RWS; Kamili A; Tandy S; Weir JM; Gaire R; Wong G; Meikle PJ; Cohn JS; Rye KA, 2013, 'Dietary Sphingomyelin Lowers Hepatic Lipid Levels and Inhibits Intestinal Cholesterol Absorption in High-Fat-Fed Mice', PLoS ONE, 8, http://dx.doi.org/10.1371/journal.pone.0055949

Chung RWS; Kamili A; Tandy S; Rye K-A; Cohn JS, 2012, 'Abstract 439: Dietary Sphingomyelin Lowers Hepatic Lipids by Inhibiting Intestinal Cholesterol Absorption in High-Fat-Fed Mice', Arteriosclerosis, Thrombosis, and Vascular Biology, 32, http://dx.doi.org/10.1161/atvb.32.suppl_1.a439

Kamili A; Wat E; Chung RW; Tandy S; Weir JM; Meikle PJ; Cohn JS, 2010, 'Hepatic accumulation of intestinal cholesterol is decreased and fecal cholesterol excretion is increased in mice fed a high-fat diet supplemented with milk phospholipids', Nutrition and Metabolism, 7, http://dx.doi.org/10.1186/1743-7075-7-90

Tandy S; Chung RWS; Kamili A; Wat E; Weir JM; Meikle PJ; Cohn JS, 2010, 'Hydrogenated phosphatidylcholine supplementation reduces hepatic lipid levels in mice fed a high-fat diet', Atherosclerosis, 213, pp. 142 - 147, http://dx.doi.org/10.1016/j.atherosclerosis.2010.07.050

Cohn JS; Kamili A; Wat E; Chung RWS; Tandy S, 2010, 'Reduction in intestinal cholesterol absorption by various food components: Mechanisms and implications', Atherosclerosis Supplements, 11, pp. 45 - 48, http://dx.doi.org/10.1016/j.atherosclerosissup.2010.04.004

Tandy S; Chung RWS; Wat E; Kamili A; Griinari M; Berge K; Cohn JS, 2010, 'Dietary krill oil significantly reduces hepatic steatosis, glycaemia and hypercholesterolaemia in high-fat-fed mice', PROCEEDINGS OF THE NUTRITION SOCIETY, 69, pp. E48 - E48, http://dx.doi.org/10.1017/S0029665109992369

Cohn JS; Kamili A; Wat E; Chung RWS; Tandy S, 2010, 'Dietary phospholipids and intestinal cholesterol absorption', Nutrients, 2, pp. 116 - 127, http://dx.doi.org/10.3390/nu2020116

Kamili A; Wat E; Tandy S; Chung WSR; Brown A; Rowney M; Cohn JS, 2010, 'P264 DIETARY MILK PHOSPHOLIPID IMPROVES DIET-INDUCED HEPATIC STEATOSIS IN MICE BY REDUCING INTESTINAL CHOLESTEROL ABSORPTION', Atherosclerosis Supplements, 11, pp. 72 - 72, http://dx.doi.org/10.1016/s1567-5688(10)70331-7

Tandy S; Chung RWS; Wat E; Kamili A; Berge K; Griinari M; Cohn JS, 2009, 'Dietary Krill Oil Supplementation Reduces Hepatic Steatosis, Glycemia, and Hypercholesterolemia in High-Fat-Fed Mice', JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 57, pp. 9339 - 9345, http://dx.doi.org/10.1021/jf9016042

Wat E; Tandy S; Kapera E; Kamili A; Chung RWS; Brown A; Rowney M; Cohn JS, 2009, 'Dietary phospholipid-rich dairy milk extract reduces hepatomegaly, hepatic steatosis and hyperlipidemia in mice fed a high-fat diet', Atherosclerosis, 205, pp. 144 - 150, http://dx.doi.org/10.1016/j.atherosclerosis.2008.12.004

Tandy S; Chung R; Wat E; Kamili A; Berge K; Griinari M; Cohn J, 2009, 'Abstract: 1031 DIETARY KRILL OIL SUPPLEMENTATION SIGNIFICANTLY REDUCES HEPATOMEGALY, HEPATIC STEATOSIS AND HYPERCHOLESTEROLEMIA IN HIGH-FAT FED MICE', Atherosclerosis Supplements, 10, pp. e395 - e395, http://dx.doi.org/10.1016/s1567-5688(09)70387-3

Cohn J; Tandy S; Wat E; Kamili A; Chung R; Rowney M; Brown A, 2009, 'Abstract: 601 DIETARY MILK PHOSPHOLIPID AS A CARDIOVASCULAR NUTRACEUTICAL', Atherosclerosis Supplements, 10, pp. e354 - e354, http://dx.doi.org/10.1016/s1567-5688(09)70350-2

Cohn JS; Wat E; Kamili A; Tandy S, 2008, 'Dietary phospholipids, hepatic lipid metabolism and cardiovascular disease', Current Opinion in Lipidology, 19, pp. 257 - 262, http://dx.doi.org/10.1097/MOL.0b013e3282ffaf96

Kim WS; Rahmanto A; Kamili A; Rye K; Guillemin GJ; Gelissen I; Jessup W; Hill A; Garner B, 2007, 'Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-beta peptide generation', The Journal of Biological Chemistry, 282, pp. 2851 - 2861

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