By Dr Angli Xue

Journal articles

Xue A; Zhu Z; Wang H; Jiang L; Visscher PM; Zeng J; Yang J, 2024, 'Unravelling the complex causal effects of substance use behaviours on common diseases', Communications Medicine, 4, http://dx.doi.org/10.1038/s43856-024-00473-3

Lim JWY; Chin VT; Keith P; McCloy R; Neavin D; Xue A; Kaczorowski D; Spenceley E; Arora H; Joshua AM; Powell J, 2024, 'Predicting immunotherapy toxicity through single-cell sequencing of peripheral immune cells: A pilot study.', Journal of Clinical Oncology, 42, pp. e14538 - e14538, http://dx.doi.org/10.1200/jco.2024.42.16_suppl.e14538

Zhou W; Cuomo A; Xue A; Kanai M; Chau G; Krishna C; Xavier R; MacArthur D; Powell J; Daly M; Neale B, 2024, 'W28. EFFICIENT AND ACCURATE MIXED MODEL ASSOCIATION TOOL FOR SINGLE-CELL EQTL ANALYSIS', European Neuropsychopharmacology, 87, pp. 115 - 116, http://dx.doi.org/10.1016/j.euroneuro.2024.08.237

Qiao Z; Sidorenko J; Revez JA; Xue A; Lu X; Pärna K; Snieder H; Visscher PM; Wray NR; Yengo L, 2023, 'Estimation and implications of the genetic architecture of fasting and non-fasting blood glucose', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-36013-1

Xue A; Yazar S; Neavin D; Powell JE, 2023, 'Pitfalls and opportunities for applying latent variables in single-cell eQTL analyses', Genome Biology, 24, http://dx.doi.org/10.1186/s13059-023-02873-5

Tyebally R; Xue A; Powell JE, 2023, 'The potential clinical impact of cell type-specific genetic regulation: Crohn's disease.', Clin Transl Med, 13, pp. e1474, http://dx.doi.org/10.1002/ctm2.1474

Xiu X; Zhang H; Xue A; Cooper DN; Yan L; Yang Y; Yang Y; Zhao H, 2022, 'Genetic evidence for a causal relationship between type 2 diabetes and peripheral artery disease in both Europeans and East Asians', BMC medicine, 20, pp. 300, http://dx.doi.org/10.1186/s12916-022-02476-0

Zhang H; Xiu X; Xue A; Yang Y; Yang Y; Zhao H, 2022, 'Mendelian randomization study reveals a population-specific putative causal effect of type 2 diabetes in risk of cataract.', Int J Epidemiol, 50, pp. 2024 - 2037, http://dx.doi.org/10.1093/ije/dyab175

Adolphe C; Xue A; Fard AT; Genovesi LA; Yang J; Wainwright BJ, 2021, 'Genetic and functional interaction network analysis reveals global enrichment of regulatory T cell genes influencing basal cell carcinoma susceptibility', Genome Medicine, 13, http://dx.doi.org/10.1186/s13073-021-00827-9

Xue A; Jiang L; Zhu Z; Wray NR; Visscher PM; Zeng J; Yang J, 2021, 'Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes', Nature Communications, 12, http://dx.doi.org/10.1038/s41467-020-20237-6

Zhang H; Xiu X; Xue A; Yang Y; Yang Y; Zhao H, 2021, 'Mendelian randomization study reveals a population-specific putative causal effect of type 2 diabetes in risk of cataract', International Journal of Epidemiology, 50, pp. 2024 - 2037, http://dx.doi.org/10.1093/ije/dyab175

Xue A; Jiang L; Zhu Z; Wray NR; Visscher PM; Zeng J; Yang J, 2021, 'Publisher Correction: Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes (Nature Communications, (2021), 12, 1, (20211), 10.1038/s41467-020-20237-6)', Nature Communications, 12, http://dx.doi.org/10.1038/s41467-021-21294-1

Zeng J; Xue A; Jiang L; Lloyd-Jones LR; Wu Y; Wang H; Zheng Z; Yengo L; Kemper KE; Goddard ME; Wray NR; Visscher PM; Yang J, 2021, 'Widespread signatures of natural selection across human complex traits and functional genomic categories', Nature Communications, 12, http://dx.doi.org/10.1038/s41467-021-21446-3

Sun X; Xue A; Qi T; Chen D; Shi D; Wu Y; Zheng Z; Zeng J; Yang J, 2021, 'Tumor mutational burden is polygenic and genetically associated with complex traits and diseases', Cancer Research, 81, pp. 1230 - 1239, http://dx.doi.org/10.1158/0008-5472.CAN-20-3459

Revez JA; Lin T; Qiao Z; Xue A; Holtz Y; Zhu Z; Zeng J; Wang H; Sidorenko J; Kemper KE; Vinkhuyzen AAE; Frater J; Eyles D; Burne THJ; Mitchell B; Martin NG; Zhu G; Visscher PM; Yang J; Wray NR; McGrath JJ, 2020, 'Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-020-15421-7

Nalls MA; Blauwendraat C; Vallerga CL; Heilbron K; Bandres-Ciga S; Chang D; Tan M; Kia DA; Noyce AJ; Xue A; Bras J; Young E; von Coelln R; Simón-Sánchez J; Schulte C; Sharma M; Krohn L; Pihlstrøm L; Siitonen A; Iwaki H; Leonard H; Faghri F; Gibbs JR; Hernandez DG; Scholz SW; Botia JA; Martinez M; Corvol JC; Lesage S; Jankovic J; Shulman LM; Sutherland M; Tienari P; Majamaa K; Toft M; Andreassen OA; Bangale T; Brice A; Yang J; Gan-Or Z; Gasser T; Heutink P; Shulman JM; Wood NW; Hinds DA; Hardy JA; Morris HR; Gratten J; Visscher PM; Graham RR; Singleton AB; Adarmes-Gómez AD; Aguilar M; Aitkulova A; Akhmetzhanov V; Alcalay RN; Alvarez I; Alvarez V; Barrero FJ; Bergareche Yarza JA; Bernal-Bernal I; Billingsley K; Blazquez M; Bonilla-Toribio M; Boungiorno MT; Brockmann K; Bubb V; Buiza-Rueda D; Cámara A; Carrillo F; Carrión-Claro M; Cerdan D; Chelban V; Clarimón J; Clarke C; Compta Y; Cookson MR; Craig DW; Danjou F; Diez-Fairen M; Dols-Icardo O; Duarte J; Duran R; Escamilla-Sevilla F; Escott-Price V; Ezquerra M; Feliz C; Fernández M; Fernández-Santiago R; Finkbeiner S; Foltynie T; Garcia C; García-Ruiz P; Gomez Heredia MJ; Gómez-Garre P; González MM; Gonzalez-Aramburu I; Guelfi S; Guerreiro R, 2019, 'Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies', The Lancet Neurology, 18, pp. 1091 - 1102, http://dx.doi.org/10.1016/S1474-4422(19)30320-5

Reynolds RH; Botía J; Nalls MA; Noyce AJ; Nicolas A; Cookson MR; Bandres-Ciga S; Gibbs JR; Hernandez DG; Singleton AB; Reed X; Leonard H; Blauwendraat C; Faghri F; Bras J; Guerreiro R; Tucci A; Kia DA; Houlden H; Plun-Favreau H; Mok KY; Wood NW; Lovering R; R’Bibo L; Rizig M; Chelban V; Trabzuni D; Tan M; Morris HR; Middlehurst B; Quinn J; Billingsley K; Holmans P; Kinghorn KJ; Lewis P; Escott-Price V; Williams N; Foltynie T; Brice A; Danjou F; Lesage S; Corvol JC; Martinez M; Giri A; Schulte C; Brockmann K; Simón-Sánchez J; Heutink P; Gasser T; Rizzu P; Sharma M; Shulman JM; Robak L; Lubbe S; Mencacci NE; Finkbeiner S; Lungu C; Scholz SW; Gan-Or Z; Rouleau GA; Krohan L; van Hilten JJ; Marinus J; Adarmes-Gómez AD; Bernal-Bernal I; Bonilla-Toribio M; Buiza-Rueda D; Carrillo F; Carrión-Claro M; Mir P; Gómez-Garre P; Jesús S; Labrador-Espinosa MA; Macias D; Vargas-González L; Méndez-del-Barrio C; Periñán-Tocino T; Tejera-Parrado C; Diez-Fairen M; Aguilar M; Alvarez I; Boungiorno MT; Carcel M; Pastor P; Tartari JP; Alvarez V; González MM; Blazquez M; Garcia C; Suarez-Sanmartin E; Barrero FJ; Rezola EM; Yarza JAB; Pagola AG; de Munain Arregui AL; Ruiz-Martínez J; Cerdan D; Duarte J; Clarimón J; Dols-Icardo O, 2019, 'Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability', npj Parkinson's Disease, 5, http://dx.doi.org/10.1038/s41531-019-0076-6

Noyce AJ; Bandres-Ciga S; Kim J; Heilbron K; Kia D; Hemani G; Xue A; Lawlor DA; Smith GD; Duran R; Gan-Or Z; Blauwendraat C; Gibbs JR; Hinds DA; Yang J; Visscher P; Cuzick J; Morris H; Hardy J; Wood NW; Nalls MA; Singleton AB, 2019, 'The Parkinson's Disease Mendelian Randomization Research Portal', Movement Disorders, 34, pp. 1864 - 1872, http://dx.doi.org/10.1002/mds.27873

Byrne EM; Ferreira MAR; Xue A; Lindström S; Jiang X; Yang J; Easton DF; Wray NR; Chenevix-Trench G, 2019, 'Is Schizophrenia a Risk Factor for Breast Cancer?-Evidence from Genetic Data', Schizophrenia Bulletin, 45, pp. 1251 - 1256, http://dx.doi.org/10.1093/schbul/sby162

Wang H; Zhang F; Zeng J; Wu Y; Kemper KE; Xue A; Zhang M; Powell JE; Goddard ME; Wray NR; Visscher PM; McRae AF; Yang J, 2019, 'Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank', Science Advances, 5, http://dx.doi.org/10.1126/sciadv.aaw3538

Xue A; Wu Y; Zhu Z; Zhang F; Kemper KE; Zheng Z; Yengo L; Lloyd-Jones LR; Sidorenko J; Wu Y; Agbessi M; Ahsan H; Alves I; Andiappan A; Awadalla P; Battle A; Beutner F; Bonder MJ; Boomsma D; Christiansen M; Claringbould A; Deelen P; Esko T; Favé MJ; Franke L; Frayling T; Gharib S; Gibson G; Hemani G; Jansen R; Kähönen M; Kalnapenkis A; Kasela S; Kettunen J; Kim Y; Kirsten H; Kovacs P; Krohn K; Kronberg-Guzman J; Kukushkina V; Kutalik Z; Lee B; Lehtimäki T; Loeffler M; Marigorta UM; Metspalu A; Milani L; Müller-Nurasyid M; Nauck M; Nivard M; Penninx B; Perola M; Pervjakova N; Pierce B; Powell J; Prokisch H; Psaty B; Raitakari O; Ring S; Ripatti S; Rotzschke O; Ruëger S; Saha A; Scholz M; Schramm K; Seppälä I; Stumvoll M; Sullivan P; Teumer A; Thiery J; Tong L; Tönjes A; van Dongen J; van Meurs J; Verlouw J; Völker U; Võsa U; Yaghootkar H; Zeng B; McRae AF; Visscher PM; Zeng J; Yang J, 2018, 'Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes', Nature Communications, 9, http://dx.doi.org/10.1038/s41467-018-04951-w

Qi T; Wu Y; Zeng J; Zhang F; Xue A; Jiang L; Zhu Z; Kemper K; Yengo L; Zheng Z; Agbessi M; Ahsan H; Alves I; Andiappan A; Awadalla P; Battle A; Beutner F; Jan Bonder M; Boomsma D; Christiansen M; Claringbould A; Deelen P; Esko T; Favé MJ; Franke L; Frayling T; Gharib S; Gibson G; Hemani G; Jansen R; Kähönen M; Kalnapenkis A; Kasela S; Kettunen J; Kim Y; Kirsten H; Kovacs P; Krohn K; Kronberg-Guzman J; Kukushkina V; Kutalik Z; Lee B; Lehtimäki T; Loeffler M; Marigorta UM; Metspalu A; Milani L; Müller-Nurasyid M; Nauck M; Nivard M; Penninx B; Perola M; Pervjakova N; Pierce B; Powell J; Prokisch H; Psaty B; Raitakari O; Ring S; Ripatti S; Rotzschke O; Ruëger S; Saha A; Scholz M; Schramm K; Seppälä I; Stumvoll M; Sullivan P; Teumer A; Thiery J; Tong L; Tönjes A; Van Dongen J; Van Meurs J; Verlouw J; Völker U; Võsa U; Yaghootkar H; Zeng B; Marioni RE; Montgomery GW; Deary IJ; Wray NR; Visscher PM; McRae AF; Yang J, 2018, 'Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood', Nature Communications, 9, http://dx.doi.org/10.1038/s41467-018-04558-1

Zeng J; De Vlaming R; Wu Y; Robinson MR; Lloyd-Jones LR; Yengo L; Yap CX; Xue A; Sidorenko J; McRae AF; Powell JE; Montgomery GW; Metspalu A; Esko T; Gibson G; Wray NR; Visscher PM; Yang J, 2018, 'Signatures of negative selection in the genetic architecture of human complex traits', Nature Genetics, 50, pp. 746 - 753, http://dx.doi.org/10.1038/s41588-018-0101-4

Xue A; Wang H; Zhu J, 2017, 'Dissecting genetic architecture of startle response in Drosophila melanogaster using multi-omics information', Scientific Reports, 7, http://dx.doi.org/10.1038/s41598-017-11676-1

Mei Y; Yu J; Xue A; Fan S; Song M; Pang C; Pei W; Yu S; Zhu J, 2017, 'Dissecting genetic network of fruit branch traits in upland cotton by association mapping using SSR markers', PLoS ONE, 12, http://dx.doi.org/10.1371/journal.pone.0162815

Wang J; Ding K; Chen Y; Zhang L; Liu Z; Xue A; Gu W; Yang X; Li X; Huang J; Xing C; Cao Y; Chen M, 2014, 'Detection of thrombin with an Aptamer-based macromolecule biosensor using bacterial ghost system', ACS Synthetic Biology, 3, pp. 963 - 965, http://dx.doi.org/10.1021/sb500018f

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