By Dr Angli Xue

Preprints

Parikh D; Xue A; Liao H-C; Wishart C; Ashhurst TM; Putri GH; Luciani F; Naik SH; Salim A; Marsh-Wakefield F; Louie RHY, 2025, Identifying the Minimal Number of Protein Markers for Cell Type Annotation Using MiniMarS, http://dx.doi.org/10.1101/2025.07.14.664825

Cheng F-F; Zhuang Y-Y; Wen X-R; Xue A; Yang J; Jin Z-B, 2019, Towards the identification of causal genes for age-related macular degeneration, http://dx.doi.org/10.1101/778613

Zeng J; Xue A; Jiang L; Lloyd-Jones LR; Wu Y; Wang H; Zheng Z; Yengo L; Kemper KE; Goddard ME; Wray NR; Visscher PM; Yang J, Bayesian analysis of GWAS summary data reveals differential signatures of natural selection across human complex traits and functional genomic categories, http://dx.doi.org/10.1101/752527

Zhou W; Cuomo ASE; Xue A; Kanai M; Chau G; Krishna C; Xavier RJ; MacArthur DG; Powell JE; Daly MJ; Neale BM, Efficient and accurate mixed model association tool for single-cell eQTL analysis, http://dx.doi.org/10.1101/2024.05.15.24307317

Nalls MA; Blauwendraat C; Vallerga CL; Heilbron K; Bandres-Ciga S; Chang D; Tan M; Kia DA; Noyce AJ; Xue A; Bras J; Young E; von Coelln R; Simón-Sánchez J; Schulte C; Sharma M; Krohn L; Pihlstrom L; Siitonen A; Iwaki H; Leonard H; Faghri F; Gibbs JR; Hernandez DG; Scholz SW; Botia JA; Martinez M; Corvol J-C; Lesage S; Jankovic J; Shulman LM; Team TAR; Consortium SGOPD; Sutherland M; Tienari P; Majamaa K; Toft M; Andreassen OA; Bangale T; Brice A; Yang J; Gan-Or Z; Gasser T; Heutink P; Shulman JM; Wood N; Hinds DA; Hardy JA; Morris HR; Gratten J; Visscher PM; Graham RR; Singleton AB; Consortium FTIPDG, Expanding Parkinson’s disease genetics: novel risk loci, genomic context, causal insights and heritable risk, http://dx.doi.org/10.1101/388165

Xue A; Fan J; Dong OA; Huang HL; Chen L; Allen PC; Spenceley E; Sagi-Zsigmond E; Bowen B; Henry A; Cuomo ASE; Tanudisastro HA; Qiao Z; Dorans E; Ben-David E; Farh KK-H; Hu L; Liu YC; Neavin D; Lee AS; Senabouth A; Bartie C; McCloy RA; Chin V; Zhou W; Price AL; de Lange KM; Figtree GA; Hewitt AW; MacArthur DG; Powell JE, Genetic regulation of cell type–specific chromatin accessibility shapes immune function and disease risk, http://dx.doi.org/10.1101/2025.08.27.25334533

Xue A; Yazar S; Alquicira-Hernández J; Cuomo ASE; Senabouth A; Gordon G; Kathail P; Ye CJ; Hewitt AW; Powell JE, Genetic variants associated with cell-type-specific intra-individual gene expression variability reveal new mechanisms of genome regulation, http://dx.doi.org/10.1101/2024.05.05.592598

Xue A; Jiang L; Zhu Z; Wray NR; Visscher PM; Zeng J; Yang J, Genome-wide analyses of behavioural traits biased by misreports and longitudinal changes, http://dx.doi.org/10.1101/2020.06.15.20131284

Revez JA; Lin T; Qiao Z; Xue A; Holtz Y; Zhu Z; Zeng J; Wang H; Sidorenko J; Kemper KE; Vinkhuyzen AA; Frater J; Eyles D; Burne TH; Mitchell B; Martin NG; Zhu G; Visscher PM; Yang J; Wray NR; McGrath JJ, Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration, http://dx.doi.org/10.1101/860767

Wang H; Zhang F; Zeng J; Wu Y; Kemper KE; Xue A; Zhang M; Powell JE; Goddard ME; Wray NR; Visscher PM; McRae AF; Yang J, Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank, http://dx.doi.org/10.1101/519538

Qi T; Wu Y; Zeng J; Zhang F; Xue A; Jiang L; Zhu Z; Kemper K; Yengo L; Zheng Z; Consortium E; Marioni RE; Montgomery GW; Deary IJ; Wray NR; Visscher PM; McRae AF; Yang J, Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood, http://dx.doi.org/10.1101/274472

Cuomo ASE; Spenceley E; Tanudisastro HA; Bowen B; Henry A; Huang HL; Xue A; Zhou W; Welland MJ; Bryen SJ; Dong OA; Lee AS; Pullin JM; Wing K; Tang O; Gray MP; Franklin M; Harper M; Silk M; Bobowik K; Stuckey A; Marshall J; Bakiris V; Uren C; Madala BS; Miniter A; Bartie C; Neavin DR; Qiao Z; Ben-David E; Chen L; Farh KK-H; Grieve SM; Nguyen T; Wallace C; Piscionere J; Siggs OM; Nicholas H; de Lange KM; Hewitt AW; Figtree GA; MacArthur DG; Powell JE, Impact of rare and common genetic variation on cell type-specific gene expression in human blood, http://dx.doi.org/10.1101/2025.03.20.25324352

Xue A; Wu Y; Zhu Z; Zhang F; Kemper KE; Zheng Z; Yengo L; Lloyd-Jones LR; Sidorenko J; Wu Y; Consortium E; McRae AF; Visscher PM; Zeng J; Yang J, Novel susceptibility loci and genetic regulation mechanisms for type 2 diabetes, http://dx.doi.org/10.1101/284570

Xue A; Yazar S; Neavin D; Powell JE, Pitfalls and opportunities for applying PEER factors in single-cell eQTL analyses, http://dx.doi.org/10.1101/2022.08.02.502566

Liu YC; Cuomo ASE; Huang Y; Perez-Schindler J; Min B; Datta S; Nambrath N; Hu L; Nam K; Kanai M; Xue A; Xavier RJ; Daly MJ; MacArthur DG; Powell JE; Claussnitzer M; Neale BM; Zhou W, Scalable context-dependent single-cell eQTL mapping reveals disease-relevant regulatory variation beyond static models, http://dx.doi.org/10.64898/2026.08.13.26360300

Henry A; Senabouth A; Tyebally R; Bowen B; Allen PC; Spenceley E; Sagi-Zsigmond E; McCloy RA; Cuomo ASE; Fan J; Huang HL; Tanudisastro HA; Xue A; Dong O; Harris BT; Alegbe T; Raine T; Anderson CA; Hemani G; de Lange KM; Figtree GA; Hewitt AW; MacArthur DG; Powell JE, Single-cell genetics identifies cell-type-specific effector genes across complex traits and diseases, http://dx.doi.org/10.1101/2025.08.28.25334614

Tanudisastro HA; Cuomo ASE; Weisburd B; Welland M; Spenceley E; Franklin M; Xue A; Huang HL; Bowen B; Fan J; Dong OA; Henry A; Allen PC; Wing K; Tang O; Gray M; Reis ALM; Margoliash J; Kurtas NE; Pullin JM; Lee AS; Brand H; Harper M; Bobowik K; Silk M; Miniter A; Marshall J; Bakiris V; Madala BS; Uren C; Bartie C; McCloy RA; Senabouth A; Dashnow H; Fearnley L; Martin-Trujillo A; Dolzhenko E; Qiao Z; Grieve SM; Nguyen T; Ben-David E; Chen L; Farh KK-H; Talkowski M; Alexander SI; Siggs OM; Gruenschloss L; Nicholas HR; Piscionere J; Simons C; Wallace C; Gymrek M; Deveson IW; Hewitt AW; Figtree GA; de Lange KM; Powell JE; MacArthur DG, Tandem repeat variation shapes immune cell type-specific gene expression, http://dx.doi.org/10.1101/2024.11.02.621562

Noyce AJ; Bandres-Ciga S; Kim J; Heilbron K; Kia D; Hemani G; Xue A; Lawlor DA; Smith GD; Duran R; Gan-Or Z; Blauwendraat C; Gibbs JR; Team AR; Consortium IPDG; Hinds DA; Yang J; Visscher P; Cuzick J; Morris H; Hardy J; Wood NW; Nalls MA; Singleton AB, The Parkinson’s Disease Mendelian Randomization Research Portal, http://dx.doi.org/10.1101/604033

Zhang H; Xiu X; Xue A; Yang Y; Yang Y; Zhao H, The putative causal effect of type 2 diabetes in risk of cataract: a Mendelian randomization study in East Asian, http://dx.doi.org/10.1101/2021.02.08.430342

Xue A; Zhu Z; Wang H; Jiang L; Visscher PM; Zeng J; Yang J, Unravelling the complex causal effects of substance use behaviours on common diseases, http://dx.doi.org/10.21203/rs.3.rs-3465061/v1

Zeng J; de Vlaming R; Wu Y; Robinson MR; Lloyd-Jones L; Yengo L; Yap C; Xue A; Sidorenko J; McRae AF; Powell JE; Montgomery GW; Metspalu A; Esko T; Gibson G; Wray NR; Visscher PM; Yang J, Widespread signatures of negative selection in the genetic architecture of human complex traits, http://dx.doi.org/10.1101/145755

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