By Dr Matthew Perry

Journal articles

Witchel HJ; Dempsey CE; Sessions RB; Perry M; Milnes JT; Hancox JC; Mitcheson JS, 2004, 'The low-potency, voltage-dependent herg blocker propafenone - Molecular determinants and drug trapping', Molecular Pharmacology, 66, pp. 1201 - 1212, http://dx.doi.org/10.1124/mol.104.001743

Perry M; De Groot MJ; Helliwell R; Leishman D; Tristani-Firouzi M; Sanguinetti MC; Mitcheson J, 2004, 'Structural determinants of HERG channel block by clofilium and ibutilide', Molecular Pharmacology, 66, pp. 240 - 249, http://dx.doi.org/10.1124/mol.104.000117

Mitcheson JS; Perry MD, 2003, 'Molecular determinants of high-affinity drug binding to HERG channels', Current Opinion in Drug Discovery and Development, 6, pp. 667 - 674

Conference Abstracts

TeBay C; MacArthur JR; Mangala M; Kerr N; Heitmann S; Perry MD; Windley MJ; Vandenberg JI; Hil AP, 2022, 'Comprehensive preclinical evaluation of how cardiac safety profiles of chloroquine and hydroxychloroquine are modified by disease associated factors', in JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, ELSEVIER SCIENCE INC, Vol. 117, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000886335100044&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hill AP; Mann SA; Imtiaz MS; Perry MD; Vandenberg JI, 2014, 'Using Clinical Datasets to Optimize Models of Human Ventricular Electrophysiology: Implications for In Silico Drug Screening', in BIOPHYSICAL JOURNAL, CELL PRESS, CA, San Francisco, Vol. 112, pp. 465A - 465A, presented at 58th Annual Meeting of the Biophysical-Society, CA, San Francisco, 15 February 2014 - 19 February 2014, http://dx.doi.org/10.1016/j.bpj.2016.11.2493

Tan PS; Perry M; Chai AN; Vandenberg JI; Hill AP, 2012, 'Bimodal Regulation of hERG Gating by the N-Terminal Tail Revealed by Voltage Clamp Fluorometry', in BIOPHYSICAL JOURNAL, CELL PRESS, CA, San Diego, Vol. 102, pp. 328A - 328A, presented at 56th Annual Meeting of the Biophysical-Society, CA, San Diego, 25 February 2012 - 29 February 2012, http://dx.doi.org/10.1016/j.bpj.2011.11.1800

Perry MD; Vandenberg JI, 2012, 'Critical Dual Role for the Pore Helix in Kv11.1 Channel Inactivation', in BIOPHYSICAL JOURNAL, CELL PRESS, CA, San Diego, Vol. 102, pp. 328A - 328A, presented at 56th Annual Meeting of the Biophysical-Society, CA, San Diego, 25 February 2012 - 29 February 2012, http://dx.doi.org/10.1016/j.bpj.2011.11.1801

Phan K; Ng C; McNitt S; Moss A; Zareba W; Perry M; Vandenberg J, 'The role of in vitro phenotypes for clinical risk stratification of sudden death in Long QT Syndrome Type 2', in Heart, Lung and Circulation, Elsevier, Vol. 24, pp. S232 - S233, presented at Heart, Lung and Circulation, http://dx.doi.org/10.1016/j.hlc.2015.06.289

Working Papers

Ballouz S; Mangala MM; Perry MD; Heitmann S; Gillis JA; Hill AP; Vandenberg JI, Co-expression of calcium channels and delayed rectifier potassium channels protects the heart from proarrhythmic events, Cold Spring Harbor Laboratory, http://dx.doi.org10.1101/659821

Preprints

TeBay C; McArthur J; Mangala M; Kerr N; Heitmann STEWART; Perry M; Windley M; VaAndenberg J; Hill A, 2021, Comprehensive preclinical evaluation of how cardiac safety profiles of potential COVID-19 drugs are modified by disease associated factors., http://dx.doi.org/10.22541/au.161429217.72966648/v1

Lei CL; Whittaker DG; Windley MJ; Perry MD; Hill AP; Mirams GR, A range of voltage-clamp protocol designs for rapid capture of hERG kinetics, http://dx.doi.org/10.1101/2024.08.14.607756

Thorpe J; Perry MD; Contreras O; Hurley E; Parker G; Harvey RP; Hill AP; Vandenberg JI, Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia, http://dx.doi.org/10.21203/rs.3.rs-2744099/v1

Ng C-A; Farr J; Young P; Windley MJ; Perry MD; Hill AP; Vandenberg JI, Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiology, http://dx.doi.org/10.1101/2021.02.02.427891

Lee W; Windley MJ; Perry MD; Vandenberg JI; Hill AP, Protocol-dependent differences in IC50 values measured in hERG assays occur in a predictable way and can be used to quantify state preference of drug binding, http://dx.doi.org/10.1101/534867

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