By Dr Yanchuan Shi

Journal articles

Zhao XY; Wang JQ; Neely GG; Shi YC; Wang QP, 2024, 'Natural compounds as obesity pharmacotherapies', Phytotherapy Research, 38, pp. 797 - 838, http://dx.doi.org/10.1002/ptr.8083

Sue N; Thai LM; Saito A; Boyer CK; Fordham AM; Yan C; Davenport A; Tao J; Bensellam M; Cantley J; Shi YC; Stephens SB; Imaizumi K; Biden TJ, 2024, 'Independent activation of CREB3L2 by glucose fills a regulatory gap in mouse β-cells by co-ordinating insulin biosynthesis with secretory granule formation', Molecular Metabolism, 79, http://dx.doi.org/10.1016/j.molmet.2023.101845

Peng S; Wu WQ; Li LY; Shi YC; Lin S; Song ZY, 2023, 'Deficiency of neuropeptide Y attenuates neointima formation after vascular injury in mice', BMC Cardiovascular Disorders, 23, http://dx.doi.org/10.1186/s12872-023-03267-y

Wang B; Wan AH; Xu Y; Zhang RX; Zhao BC; Zhao XY; Shi YC; Zhang X; Xue Y; Luo Y; Deng Y; Neely GG; Wan G; Wang QP, 2023, 'Identification of indocyanine green as a STT3B inhibitor against mushroom α-amanitin cytotoxicity', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-37714-3

Li Y; Buys N; Ferguson S; Li Z; Shi YC; Li L; Sun J, 2023, 'The evaluation of cognitive-behavioral therapy-based intervention on type 2 diabetes patients with comorbid metabolic syndrome: a randomized controlled trial', Diabetology and Metabolic Syndrome, 15, http://dx.doi.org/10.1186/s13098-023-01100-2

Chen WH; Shi YC; Huang QY; Chen JM; Wang ZY; Lin S; Shi QY, 2023, 'Potential for NPY receptor–related therapies for polycystic ovary syndrome: an updated review', Hormones, 22, pp. 441 - 451, http://dx.doi.org/10.1007/s42000-023-00460-8

Ip CK; Rezitis J; Qi Y; Bajaj N; Koller J; Farzi A; Shi YC; Tasan R; Zhang L; Herzog H, 2023, 'Critical role of lateral habenula circuits in the control of stress-induced palatable food consumption', Neuron, 111, pp. 2583 - 2600.e6, http://dx.doi.org/10.1016/j.neuron.2023.05.010

Zheng J; Chen L; Cai G; Wang Y; Huang J; Lin X; Li Y; Yu Q; Chen X; Shi Y; Ye Q, 2023, 'The effect of Parkin gene S/N 167 polymorphism on resting spontaneous brain functional activity in Parkinson's Disease', Parkinsonism and Related Disorders, 113, http://dx.doi.org/10.1016/j.parkreldis.2023.105484

Wu Q; Burley G; Li LC; Lin S; Shi YC, 2023, 'The role of dietary salt in metabolism and energy balance: Insights beyond cardiovascular disease', Diabetes, Obesity and Metabolism, 25, pp. 1147 - 1161, http://dx.doi.org/10.1111/dom.14980

Conway JRW; Warren SC; Lee YK; McCulloch AT; Magenau A; Lee V; Metcalf XL; Stoehr J; Haigh K; Abdulkhalek L; Guaman CS; Reed DA; Murphy KJ; Pereira BA; Mélénec P; Chambers C; Latham SL; Lenthall H; Deenick EK; Ma Y; Phan T; Lim E; Joshua AM; Walters S; Grey ST; Shi YC; Zhang L; Herzog H; Croucher DR; Philp A; Scheele CLGJ; Herrmann D; Sansom OJ; Morton JP; Papa A; Haigh JJ; Nobis M; Timpson P, 2023, 'Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse', Science Advances, 9, http://dx.doi.org/10.1126/sciadv.adf9063

Thai LM; O'Reilly L; Reibe-Pal S; Sue N; Holliday H; Small L; Schmitz-Peiffer C; Dhenni R; Wang-Wei Tsai V; Norris N; Yau B; Zhang X; Lee K; Yan C; Shi YC; Kebede MA; Brink R; Cooney GJ; Irvine KM; Breit SN; Phan TG; Swarbrick A; Biden TJ, 2023, 'β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling', iScience, 26, http://dx.doi.org/10.1016/j.isci.2023.106477

Shi YC, 2023, 'ACE2: A Dilemma in Regulating SARS-CoV-2 Infection and its Metabolic Complications', BIO Integration, 4, pp. 3 - 6, http://dx.doi.org/10.15212/bioi-2022-0026

Liang B; Burley G; Lin S; Shi YC, 2022, 'Osteoporosis pathogenesis and treatment: existing and emerging avenues', Cellular and Molecular Biology Letters, 27, http://dx.doi.org/10.1186/s11658-022-00371-3

Cai PY; Zheng YL; Zhou YF; Wang WD; Li MM; Shi YC; Lin HL; Lin S, 2022, 'Research progress on the role of exosomes in obstructive sleep apnea-hypopnea syndrome-related atherosclerosis', Sleep Medicine Reviews, 66, http://dx.doi.org/10.1016/j.smrv.2022.101696

Yang YS; He SL; Chen WC; Wang CM; Huang QM; Shi YC; Lin S; He HF, 2022, 'Recent progress on the role of non-coding RNA in postoperative cognitive dysfunction', Frontiers in Cellular Neuroscience, 16, http://dx.doi.org/10.3389/fncel.2022.1024475

Lai JQ; Shi YC; Lin S; Chen XR, 2022, 'Metabolic disorders on cognitive dysfunction after traumatic brain injury', Trends in Endocrinology and Metabolism, 33, pp. 451 - 462, http://dx.doi.org/10.1016/j.tem.2022.04.003

Lee K; Chan JY; Liang C; Ip CK; Shi YC; Herzog H; Hughes WE; Bensellam M; Delghingaro-Augusto V; Koina ME; Nolan CJ; Laybutt DR, 2022, 'XBP1 maintains beta cell identity, represses beta-to-alpha cell transdifferentiation and protects against diabetic beta cell failure during metabolic stress in mice', Diabetologia, 65, pp. 984 - 996, http://dx.doi.org/10.1007/s00125-022-05669-7

Zhang CL; Lin YZ; Wu Q; Yan C; Wong MWK; Zeng F; Zhu P; Bowes K; Lee K; Zhang X; Song ZY; Lin S; Shi YC, 2022, 'Arcuate NPY is involved in salt-induced hypertension via modulation of paraventricular vasopressin and brain-derived neurotrophic factor', Journal of Cellular Physiology, 237, pp. 2574 - 2588, http://dx.doi.org/10.1002/jcp.30719

Zammit NW; McDowell J; Warren J; Muskovic W; Gamble J; Shi YC; Kaczorowski D; Chan CL; Powell J; Ormandy C; Brown D; Oakes SR; Grey ST, 2022, 'TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation', Frontiers in Immunology, 13, http://dx.doi.org/10.3389/fimmu.2022.811525

Yang CH; Ann-Onda D; Lin X; Fynch S; Nadarajah S; Pappas EG; Liu X; Scott JW; Oakhill JS; Galic S; Shi Y; Moreno-Asso A; Smith C; Loudovaris T; Levinger I; Eizirik DL; Laybutt DR; Herzog H; Thomas HE; Loh K, 2022, 'Neuropeptide Y1 receptor antagonism protects β-cells and improves glycemic control in type 2 diabetes', Molecular Metabolism, 55, http://dx.doi.org/10.1016/j.molmet.2021.101413

Yu J; Shi YC; Ping F; Li W; Zhang HB; He SL; Zhao Y; Xu LL; Li YX, 2021, 'Liraglutide Inhibits Osteoclastogenesis and Improves Bone Loss by Downregulating Trem2 in Female Type 1 Diabetic Mice: Findings From Transcriptomics', Frontiers in Endocrinology, 12, http://dx.doi.org/10.3389/fendo.2021.763646

Yan C; Zeng T; Lee K; Nobis M; Loh K; Gou L; Xia Z; Gao Z; Bensellam M; Hughes W; Lau J; Zhang L; Ip CK; Enriquez R; Gao H; Wang QP; Wu Q; Haigh JJ; Laybutt DR; Timpson P; Herzog H; Shi YC, 2021, 'Peripheral-specific Y1 receptor antagonism increases thermogenesis and protects against diet-induced obesity', Nature Communications, 12, http://dx.doi.org/10.1038/s41467-021-22925-3

Zhang Y; Liu CY; Chen WC; Shi YC; Wang CM; Lin S; He HF, 2021, 'Regulation of neuropeptide Y in body microenvironments and its potential application in therapies: a review', Cell and Bioscience, 11, http://dx.doi.org/10.1186/s13578-021-00657-7

Zhao YX; Chen SR; Huang QY; Chen WC; Xia T; Shi YC; Gao HZ; Shi QY; Lin S, 2021, 'Repair abilities of mouse autologous adipose-derived stem cells and ShakeGel™3D complex local injection with intrauterine adhesion by BMP7-Smad5 signaling pathway activation', Stem Cell Research and Therapy, 12, pp. 191, http://dx.doi.org/10.1186/s13287-021-02258-0

Wu W; Peng S; Shi Y; Li L; Song Z; Lin S, 2021, 'NPY promotes macrophage migration by upregulating matrix metalloproteinase-8 expression', Journal of Cellular Physiology, 236, pp. 1903 - 1912, http://dx.doi.org/10.1002/jcp.29973

Wan XQ; Zeng F; Huang XF; Yang HQ; Wang L; Shi YC; Zhang ZH; Lin S, 2020, 'Risperidone stimulates food intake and induces body weight gain via the hypothalamic arcuate nucleus 5-HT2c receptor—NPY pathway', CNS Neuroscience and Therapeutics, 26, pp. 558 - 566, http://dx.doi.org/10.1111/cns.13281

Wang QP; Lin YQ; Lai ML; Su Z; Oyston LJ; Clark T; Park SJ; Khuong TM; Lau MT; Shenton V; Shi YC; James DE; Ja WW; Herzog H; Simpson SJ; Neely GG, 2020, 'PGC1α Controls Sucrose Taste Sensitization in Drosophila', Cell Reports, 31, http://dx.doi.org/10.1016/j.celrep.2020.03.044

Hu X; Zhou J; Song SS; Kong W; Shi YC; Chen LL; Zeng TS, 2020, 'TLR4/AP-1-Targeted Anti-Inflammatory Intervention Attenuates Insulin Sensitivity and Liver Steatosis', Mediators of Inflammation, 2020, http://dx.doi.org/10.1155/2020/2960517

Bensellam M; Shi YC; Chan JY; Laybutt DR; Chae H; Abou-Samra M; Pappas EG; Thomas HE; Gilon P; Jonas JC, 2019, 'Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans', Diabetologia, 62, pp. 2273 - 2286, http://dx.doi.org/10.1007/s00125-019-05008-3

Liu Y; Yu J; Shi YC; Zhang Y; Lin S, 2019, 'The role of inflammation and endoplasmic reticulum stress in obesity-related cognitive impairment', Life Sciences, 233, http://dx.doi.org/10.1016/j.lfs.2019.116707

Ip CK; Zhang L; Farzi A; Qi Y; Clarke I; Reed F; Shi YC; Enriquez R; Dayas C; Graham B; Begg D; Brüning JC; Lee NJ; Hernandez-Sanchez D; Gopalasingam G; Koller J; Tasan R; Sperk G; Herzog H, 2019, 'Amygdala NPY Circuits Promote the Development of Accelerated Obesity under Chronic Stress Conditions', Cell Metabolism, 30, pp. 111 - 128.e6, http://dx.doi.org/10.1016/j.cmet.2019.04.001

Yi TY; Chen WH; Wu YM; Zhang MF; Zhan AL; Chen YH; Wu ZZ; Shi YC; Chen BL, 2019, 'Microcatheter "first-Pass Effect" Predicts Acute Intracranial Artery Atherosclerotic Disease-Related Occlusion', Clinical Neurosurgery, 84, pp. 1296 - 1305, http://dx.doi.org/10.1093/neuros/nyy183

Chen X; Zhou Y-L; Liang S-Y; Shi Y-C; Lin S; Shu M-Q, 2019, 'Overexpression of UHRF1 promoted the proliferation of vascular smooth cells via the regulation of Geminin protein levels', BIOSCIENCE REPORTS, 39, http://dx.doi.org/10.1042/BSR20181341

Zhao YX; Chen SR; Su PP; Huang FH; Shi YC; Shi QY; Lin S, 2019, 'Using Mesenchymal Stem Cells to Treat Female Infertility: An Update on Female Reproductive Diseases', Stem Cells International, 2019, http://dx.doi.org/10.1155/2019/9071720

Loh K; Shi YC; Bensellam M; Lee K; Laybutt DR; Herzog H, 2018, 'Y1 receptor deficiency in β-cells leads to increased adiposity and impaired glucose metabolism', Scientific Reports, 8, http://dx.doi.org/10.1038/s41598-018-30140-2

Zhu P; Zhang ZH; Huang XF; Shi YC; Khandekar N; Yang HQ; Liang SY; Song ZY; Lin S, 2018, 'Cold exposure promotes obesity and impairs glucose homeostasis in mice subjected to a high-fat diet', Molecular Medicine Reports, 18, pp. 3923 - 3931, http://dx.doi.org/10.3892/mmr.2018.9382

Farzi A; Lau J; Ip CK; Qi Y; Shi YC; Zhang L; Tasan R; Sperk G; Herzog H, 2018, 'Arcuate nucleus and lateral hypothalamic cart neurons in the mouse brain exert opposing effects on energy expenditure', eLife, 7, http://dx.doi.org/10.7554/eLife.36494

Lau J; Farzi A; Qi Y; Heilbronn R; Mietzsch M; Shi YC; Herzog H, 2018, 'CART neurons in the arcuate nucleus and lateral hypothalamic area exert differential controls on energy homeostasis', Molecular Metabolism, 7, pp. 102 - 118, http://dx.doi.org/10.1016/j.molmet.2017.10.015

Lau J; Farzi A; Enriquez RF; Shi YC; Herzog H, 2017, 'GPR88 is a critical regulator of feeding and body composition in mice', Scientific Reports, 7, pp. 9912, http://dx.doi.org/10.1038/s41598-017-10058-x

Loh K; Shi YC; Walters S; Bensellam M; Lee K; Dezaki K; Nakata M; Ip CK; Chan JY; Gurzov EN; Thomas HE; Waibel M; Cantley J; Kay TW; Yada T; Laybutt DR; Grey ST; Herzog H, 2017, 'Inhibition of Y1 receptor signaling improves islet transplant outcome', Nature Communications, 8, http://dx.doi.org/10.1038/s41467-017-00624-2

Shi YC; Ip CK; Reed F; Sarruf DA; Wulff BS; Herzog H, 2017, 'Y5 receptor signalling counteracts the anorectic effects of PYY3-36 in diet-induced obese mice', Journal of Neuroendocrinology, 29, http://dx.doi.org/10.1111/jne.12483

Worton LE; Shi YC; Smith EJ; Barry SC; Gonda TJ; Whitehead JP; Gardiner EM, 2017, 'Ectodermal-Neural Cortex 1 Isoforms Have Contrasting Effects on MC3T3-E1 Osteoblast Mineralization and Gene Expression', Journal of Cellular Biochemistry, 118, pp. 2141 - 2150, http://dx.doi.org/10.1002/jcb.25851

Sun WW; Zhu P; Shi YC; Zhang CL; Huang XF; Liang SY; Song ZY; Lin S, 2017, 'Current views on neuropeptide y and diabetes-related atherosclerosis', Diabetes and Vascular Disease Research, 14, pp. 277 - 284, http://dx.doi.org/10.1177/1479164117704380

Sun WW; Li LY; Huang XF; Shi YC; Yang HQ; Song ZY; Lin S, 2017, 'The central mechanism of risperidone-induced hyperprolactinemia', Progress in Neuro-Psychopharmacology and Biological Psychiatry, 76, pp. 134 - 139, http://dx.doi.org/10.1016/j.pnpbp.2017.03.009

Sun W-W; Li L-Y; Huang X-F; Shi Y-C; Yang H-Q; Song Z-Y; Lin S, 2017, 'The central mechanism of risperidone-induced hyperprolactinemia', PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 76, pp. 134 - 139, http://dx.doi.org/10.1016/j.pnpbp.2017.03.009

Lau J; Shi YC; Herzog H, 2016, 'Temperature dependence of the control of energy homeostasis requires CART signaling', Neuropeptides, 59, pp. 97 - 109, http://dx.doi.org/10.1016/j.npep.2016.03.006

Seimon RV; Shi YC; Slack K; Lee K; Fernando HA; Nguyen AD; Zhang L; Lin S; Enriquez RF; Lau J; Herzog H; Sainsbury A, 2016, 'Intermittent Moderate Energy Restriction Improves Weight Loss Efficiency in Diet-Induced Obese Mice', PLoS ONE, 11, http://dx.doi.org/10.1371/journal.pone.0145157

Shi YC; Loh K; Bensellam M; Lee K; Zhai L; Lau J; Cantley J; Luzuriaga J; Laybutt DR; Herzog H, 2015, 'Pancreatic PYY is critical in the control of insulin secretion and glucose homeostasis in female mice', Endocrinology (United States), 156, pp. 3122 - 3136, http://dx.doi.org/10.1210/en.2015-1168

Loh K; Herzog H; Shi YC, 2015, 'Regulation of energy homeostasis by the NPY system', Trends in Endocrinology and Metabolism, 26, pp. 125 - 135, http://dx.doi.org/10.1016/j.tem.2015.01.003

Baldock PA; Lin S; Zhang L; Karl T; Shi Y; Driessler F; Zengin A; Hörmer B; Lee NJ; Wong IPL; Lin EJD; Enriquez RF; Stehrer B; During MJ; Yulyaningsih E; Zolotukhin S; Ruohonen ST; Savontaus E; Sainsbury A; Herzog H, 2014, 'Neuropeptide Y attenuates stress-induced bone loss through suppression of noradrenaline circuits', Journal of Bone and Mineral Research, 29, pp. 2238 - 2249, http://dx.doi.org/10.1002/jbmr.2205

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