By Dr Yoshiro Okubo

Journal articles

Namiki C; Takita Y; Iwata A; Momose T; Senda M; Okubo Y; Joshi AD; Lu M; Agbulos A; Breault C; Pontecorvo MJ, 2015, 'Imaging characteristics and safety of florbetapir (¹⁸F) in Japanese healthy volunteers, patients with mild cognitive impairment and patients with Alzheimer’s disease', Annals of Nuclear Medicine, 29, pp. 570 - 581, http://dx.doi.org/10.1007/s12149-015-0978-2

Tateno A; Sakayori T; Higuchi M; Suhara T; Ishihara K; Kumita S; Suzuki H; Okubo Y, 2015, 'Amyloid imaging with [¹⁸F]florbetapir in geriatric depression: Early-onset versus late-onset', International Journal of Geriatric Psychiatry, 30, pp. 720 - 728, http://dx.doi.org/10.1002/gps.4215

Asami T; Yanase M; Nomura T; Okubo Y, 2015, 'Treatment for female patients with eating disorders in the largest medical prison in Japan', BioPsychoSocial Medicine, 9, http://dx.doi.org/10.1186/s13030-015-0040-6

Tateno A; Sakayori T; Kawashima Y; Higuchi M; Suhara T; Mizumura S; Mintun MA; Skovronsky DM; Honjo K; Ishihara K; Kumita S; Suzuki H; Okubo Y, 2015, 'Comparison of imaging biomarkers for Alzheimer's disease: Amyloid imaging with [¹⁸F]florbetapir positron emission tomography and magnetic resonance imaging voxel-based analysis for entorhinal cortex atrophy', International Journal of Geriatric Psychiatry, 30, pp. 505 - 513, http://dx.doi.org/10.1002/gps.4173

Shimoda K; Kimura M; Yokota M; Okubo Y, 2015, 'Comparison of regional gray matter volume abnormalities in Alzheimer's disease and late life depression with hippocampal atrophy using VSRAD analysis: A voxel-based morphometry study', Psychiatry Research - Neuroimaging, 232, pp. 71 - 75, http://dx.doi.org/10.1016/j.pscychresns.2015.01.018

Koeda M; Watanabe A; Tsuda K; Matsumoto M; Ikeda Y; Kim W; Tateno A; Naing BT; Karibe H; Shimada T; Suzuki H; Matsuura M; Okubo Y, 2015, 'Interaction effect between handedness and CNTNAP2 polymorphism (rs7794745 genotype) on voice-specific frontotemporal activity in healthy individuals: An fMRI study', Frontiers in Behavioral Neuroscience, 9, http://dx.doi.org/10.3389/fnbeh.2015.00087

Figueroa R; Seino S; Yabushita N; Okubo Y; Nemoto M; Jung S; Tanaka K, 2015, 'Cross-Validity and Reliability of the Age Scale for Assessing Activities of Daily Living among Japanese Community-Dwelling Adults Aged 75 Years or Older', Journal of Aging and Gerontology, 3, pp. 17 - 23, http://dx.doi.org/10.12974/2309-6128.2015.03.01.3

Osuka Y; Yabushita N; Kim M; Seino S; Nemoto M; Jung S; Okubo Y; Figueroa R; Tanaka K, 2015, 'Association between habitual light-intensity physical activity and lower-extremity performance: A cross-sectional study of community-dwelling older Japanese adults', Geriatrics and Gerontology International, 15, pp. 268 - 275, http://dx.doi.org/10.1111/ggi.12268

Kurita M; Nishino S; Numata Y; Okubo Y; Sato T, 2015, 'The noradrenaline metabolite MHPG is a candidate biomarker between the depressive, remission, and manic states in bipolar disorder I: Two long-term naturalistic case reports', Neuropsychiatric Disease and Treatment, 11, pp. 353 - 358, http://dx.doi.org/10.2147/NDT.S74550

Figueroa R; Seino S; Yabushita N; Okubo Y; Osuka Y; Nemoto M; Jung S; Tanaka K, 2015, 'Age Scale for Assessing Activities of Daily Living', International Journal of Statistics in Medical Research, 4, pp. 48 - 56, http://dx.doi.org/10.6000/1929-6029.2015.04.01.5

Tateno A; Sakayori T; Takizawa Y; Yamamoto K; Minagawa K; Okubo Y, 2015, 'A case of Alzheimer's disease following mild traumatic brain injury', General Hospital Psychiatry, 37, pp. 97.e7 - 97.e9, http://dx.doi.org/10.1016/j.genhosppsych.2014.09.016

Osuka Y; Jung S; Kim T; Okubo Y; Kim E; Tanaka K, 2015, 'Effects of exercise for older married couples on exercise adherence and physical fitness', Japanese Journal of Physical Fitness and Sports Medicine, 64, pp. 407 - 418, http://dx.doi.org/10.7600/jspfsm.64.407

Okubo Y; Seino S; Yabushita N; Osuka Y; Jung S; Nemoto M; Figueroa R; Tanaka K, 2015, 'Longitudinal association between habitual walking and fall occurrences among community-dwelling older adults: Analyzing the different risks of falling', Archives of Gerontology and Geriatrics, 60, pp. 45 - 51, http://dx.doi.org/10.1016/j.archger.2014.10.008

Osuka Y; Yabushita N; Seino S; Okubo Y; Jung S; Nemoto M; Figueroa R; Tanaka K, 2015, 'Translating physical activity reference value for older adults to the number of steps per day', Japanese Journal of Physical Fitness and Sports Medicine, 64, pp. 243 - 250, http://dx.doi.org/10.7600/jspfsm.64.243

Kawanishi C; Aruga T; Ishizuka N; Yonemoto N; Otsuka K; Kamijo Y; Okubo Y; Ikeshita K; Sakai A; Miyaoka H; Hitomi Y; Iwakuma A; Kinoshita T; Akiyoshi J; Horikawa N; Hirotsune H; Eto N; Iwata N; Kohno M; Iwanami A; Mimura M; Asada T; Hirayasu Y, 2014, 'Assertive case management versus enhanced usual care for people with mental health problems who had attempted suicide and were admitted to hospital emergency departments in Japan (ACTION-J): A multicentre, randomised controlled trial', The Lancet Psychiatry, 1, pp. 193 - 201, http://dx.doi.org/10.1016/S2215-0366(14)70259-7

Kurita M; Nishino S; Numata Y; Okubo Y; Sato T, 2014, 'The noradrenaline metabolite MHPG is a candidate biomarker from the manic to the remission state in bipolar disorder I: A clinical naturalistic study', PLoS ONE, 9, http://dx.doi.org/10.1371/journal.pone.0100634

Asami T; Okubo Y; Sekine M; Nomura T, 2014, 'Eating disorders among patients incarcerated only for repeated shoplifting: A retrospective quasi-case-control study in a medical prison in Japan', BMC Psychiatry, 14, http://dx.doi.org/10.1186/1471-244X-14-169

Narishige R; Kawashima Y; Otaka Y; Saito T; Okubo Y, 2014, 'Gender differences in suicide attempters: A retrospective study of precipitating factors for suicide attempts at a critical emergency unit in Japan', BMC Psychiatry, 14, http://dx.doi.org/10.1186/1471-244X-14-144

Suzuki M; Ito H; Kodaka F; Takano H; Kimura Y; Fujiwara H; Sasaki T; Takahata K; Nogami T; Nagashima T; Nengaki N; Kawamura K; Zhang MR; Varrone A; Halldin C; Okubo Y; Suhara T, 2014, 'Reproducibility of PET measurement for presynaptic dopaminergic functions using L-[β-¹¹C]DOPA and [¹⁸F]FE-PE2I in humans', Nuclear Medicine Communications, 35, pp. 231 - 237, http://dx.doi.org/10.1097/MNM.0000000000000052

Osuka Y; Yabushita N; Kim M; Seino S; Nemoto M; Jung S; Okubo Y; Figueroa R; Tanaka K, 2014, 'Is habitual sedentary behaviour time associated with lower extremity performance independent of moderate- to vigorous-intensity physical activity in older adults? Cross-sectional analysis using uniaxial accelerometer', Japanese Journal of Physical Fitness and Sports Medicine, 63, pp. 169 - 176, http://dx.doi.org/10.7600/jspfsm.63.169

Shingai Y; Tateno A; Arakawa R; Sakayori T; Kim W; Suzuki H; Okubo Y, 2014, 'Age-related decline in dopamine transporter in human brain using PET with a new radioligand [¹⁸F]FE-PE2I', Annals of Nuclear Medicine, 28, pp. 220 - 226, http://dx.doi.org/10.1007/s12149-013-0798-1

Tateno A; Sakayori T; Okubo Y, 2014, 'Amyloid positron emission Tomography imaging for the differential diagnosis of Alzheimer's Disease', Journal of Nippon Medical School, 81, pp. 2 - 3, http://dx.doi.org/10.1272/jnms.81.2

Okubo Y; Sairenchi T; Irie F; Yamagishi K; Iso H; Watanabe H; Muto T; Tanaka K; Ota H, 2014, 'Association of alcohol consumption with incident hypertension among middle-aged and older Japanese population: The Ibarakai prefectural health study (IPHS)', Hypertension, 63, pp. 41 - 47, http://dx.doi.org/10.1161/HYPERTENSIONAHA.113.01585

Sakayori T; Tateno A; Arakawa R; Ikeda Y; Suzuki H; Okubo Y, 2014, 'Effect of mazindol on extracellular dopamine concentration in human brain measured by PET', Psychopharmacology, 231, pp. 2321 - 2325, http://dx.doi.org/10.1007/s00213-013-3392-2

Okubo Y; Seino S; Yabushita N; Osuka Y; Yosuke S; Nemoto M; Kim MJ; Figueroa R; Tanaka K, 2014, 'Habitual exercise and falls among community-dwelling older Japanese adults', Japanese Journal of Physical Fitness and Sports Medicine, 63, pp. 391 - 400, http://dx.doi.org/10.7600/jspfsm.63.391

Kim WC; Tateno A; Arakawa R; Sakayori T; Ikeda Y; Suzuki H; Okubo Y, 2014, 'In vivo activity of modafinil on dopamine transporter measured with positron emission tomography and [¹⁸F]FE-PE2I', International Journal of Neuropsychopharmacology, 17, pp. 697 - 703, http://dx.doi.org/10.1017/S1461145713001612

Funayama T; Ikeda Y; Tateno A; Takahashi H; Okubo Y; Fukayama H; Suzuki H, 2014, 'Modafinil augments brain activation associated with reward anticipation in the nucleus accumbens', Psychopharmacology, 231, pp. 3217 - 3228, http://dx.doi.org/10.1007/s00213-014-3499-0

Takano H; Arakawa R; Nogami T; Suzuki M; Nagashima T; Fujiwara H; Kimura Y; Kodaka F; Takahata K; Shimada H; Murakami Y; Tateno A; Yamada M; Ito H; Kawamura K; Zhang MR; Takahashi H; Kato M; Okubo Y; Suhara T, 2014, 'Norepinephrine transporter occupancy by nortriptyline in patients with depression: A positron emission tomography study with (S,S)-[ ¹⁸F]FMeNER-D2', International Journal of Neuropsychopharmacology, 17, pp. 553 - 560, http://dx.doi.org/10.1017/S1461145713001521

Ogawa K; Tateno A; Arakawa R; Sakayori T; Ikeda Y; Suzuki H; Okubo Y, 2014, 'Occupancy of serotonin transporter by tramadol: A positron emission tomography study with [¹¹C]DASB', International Journal of Neuropsychopharmacology, 17, pp. 845 - 850, http://dx.doi.org/10.1017/S1461145713001764

Osuka Y; Yabushita N; Kim M; Seino S; Nemoto M; Jung S; Okubo Y; Figueroa R; Tanaka K, 2014, 'Association between objectively measured habitual physical activity levels and mobility limitation: A cross-sectional study of community-dwelling older Japanese women', The Journal of Physical Fitness and Sports Medicine, 3, pp. 131 - 137, http://dx.doi.org/10.7600/jpfsm.3.131

Okubo Y; Osuka Y; Jung S; Figueroa R; Tsujimoto T; Aiba T; Kim T; Tanaka K, 2014, 'Effects of walking on physical and psychological fall-related factors in community-dwelling older adults: Walking versus balance program', The Journal of Physical Fitness and Sports Medicine, 3, pp. 515 - 524, http://dx.doi.org/10.7600/jpfsm.3.515

Takahashi S; Suzuki M; Matsushima E; Ohta K; Kurachi M; Hayashi T; Morita K; Maeda H; Katayama S; Hirayasu Y; Okubo Y; Uchiyama M; Kojima T, 2013, '[Association of clinical symptom between schizophrenia and exploratory eye movement].', Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 115, pp. 3 - 9

Hirano J; Watanabe K; Suzuki T; Uchida H; Den R; Kishimoto T; Nagasawa T; Tomita Y; Hara K; Ochi H; Kobayashi Y; Ishii M; Fujita A; Kanai Y; Goto M; Hayashi H; Inamura K; Ooshima F; Sumida M; Ozawa T; Sekigawa K; Nagaoka M; Yoshimura K; Konishi M; Inagaki A; Saito T; Motohashi N; Mimura M; Okubo Y; Kato M, 2013, 'An open-label study of algorithm-based treatment versus treatment-as-usual for patients with schizophrenia', Neuropsychiatric Disease and Treatment, 9, pp. 1553 - 1564, http://dx.doi.org/10.2147/NDT.S46108

Teranishi M; Kurita M; Nishino S; Takeyoshi K; Numata Y; Sato T; Tateno A; Okubo Y, 2013, 'Efficacy and tolerability of risperidone, yokukansan, and fluvoxamine for the treatment of behavioral and psychological symptoms of dementia: A blinded, randomized trial', Journal of Clinical Psychopharmacology, 33, pp. 600 - 607, http://dx.doi.org/10.1097/JCP.0b013e31829798d5

Seino S; Yabushita N; Kim MJ; Nemoto M; Jung S; Osuka Y; Okubo Y; Figueroa R; Matsuo T; Tanaka K, 2013, 'Physical performance measures as a useful indicator of multiple geriatric syndromes in women aged 75 years and older', Geriatrics and Gerontology International, 13, pp. 901 - 910, http://dx.doi.org/10.1111/ggi.12029

Jung S; Seino S; Yabushita N; Kim M; Nemoto M; Osuka Y; Okubo Y; Tanaka K, 2013, 'Cross-sectional association between body mass index and muscle strength, and mobility limitation in community-dwelling older women', Japanese Journal of Physical Fitness and Sports Medicine, 62, pp. 323 - 330, http://dx.doi.org/10.7600/jspfsm.62.323

Saji K; Ikeda Y; Kim W; Shingai Y; Tateno A; Takahashi H; Okubo Y; Fukayama H; Suzuki H, 2013, 'Acute NK1 receptor antagonist administration affects reward incentive anticipation processing in healthy volunteers', International Journal of Neuropsychopharmacology, 16, pp. 1461 - 1471, http://dx.doi.org/10.1017/S1461145712001678

Nogami T; Takano H; Arakawa R; Ichimiya T; Fujiwara H; Kimura Y; Kodaka F; Sasaki T; Takahata K; Suzuki M; Nagashima T; Mori T; Shimada H; Fukuda H; Sekine M; Tateno A; Takahashi H; Ito H; Okubo Y; Suhara T, 2013, 'Occupancy of serotonin and norepinephrine transporter by milnacipran in patients with major depressive disorder: A positron emission tomography study with [¹¹C]DASB and (S,S)-[¹⁸F]FMeNER-D2', International Journal of Neuropsychopharmacology, 16, pp. 937 - 943, http://dx.doi.org/10.1017/S1461145712001009

Koeda M; Takahashi H; Matsuura M; Aai K; Okubo Y, 2013, 'Cerebral responses to vocal attractiveness and auditory hallucinations in schizophrenia: a functional MRI study', FRONTIERS IN HUMAN NEUROSCIENCE, 7, http://dx.doi.org/10.3389/fnhum.2013.00221

Tateno A; Arakawa R; Okumura M; Fukuta H; Honjo K; Ishihara K; Nakamura H; Kumita SI; Okubo Y, 2013, 'Striatal and extrastriatal dopamine D2 receptor occupancy by a novel antipsychotic, blonanserin: A PET study with [¹¹C]raclopride and [¹¹C]FLB 457 in schizophrenia', Journal of Clinical Psychopharmacology, 33, pp. 162 - 169, http://dx.doi.org/10.1097/JCP.0b013e3182825bce

Ueda S; Marutani T; Okubo Y, 2013, '[Cenesthopathy in the presenium associated with manic factor resolved with lithium carbonate: two female cases with underlying manic or mixed state].', Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 115, pp. 127 - 138

Fukuta H; Ito I; Tateno A; Nogami T; Taiji Y; Arakawa R; Suhara T; Asai K; Okubo Y, 2013, '[Effect of menopause on morphological changes of the brain in schizophrenia].', Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 115, pp. 1178 - 1185

Koeda M; Belin P; Hama T; Masuda T; Matsuura M; Okubo Y, 2013, 'Cross-cultural differences in the processing of non-verbal affective vocalizations by Japanese and Canadian listeners', Frontiers in Psychology, 4, http://dx.doi.org/10.3389/fpsyg.2013.00105

Fukuta H; Ito I; Tateno A; Nogami T; Taiji Y; Arakawa R; Suhara T; Asai K; Okubo Y, 2013, 'Effects of menopause on brain structural changes in schizophrenia', Psychiatry and Clinical Neurosciences, 67, pp. 3 - 11, http://dx.doi.org/10.1111/pcn.12003

Takahashi H; Fujie S; Camerer C; Arakawa R; Takano H; Kodaka F; Matsui H; Ideno T; Okubo S; Takemura K; Yamada M; Eguchi Y; Murai T; Okubo Y; Kato M; Ito H; Suhara T, 2013, 'Norepinephrine in the brain is associated with aversion to financial loss', Molecular Psychiatry, 18, pp. 3 - 4, http://dx.doi.org/10.1038/mp.2012.7

Omori A; Tateno A; Ideno T; Takahashi H; Kawashima Y; Takemura K; Okubo Y, 2012, 'Influence of contact with schizophrenia on implicit attitudes towards schizophrenia patients held by clinical residents', BMC Psychiatry, 12, http://dx.doi.org/10.1186/1471-244X-12-205

Kawashima Y; Ito T; Narishige R; Saito T; Okubo Y, 2012, 'The characteristics of serious suicide attempters in Japanese adolescents- comparison study between adolescents and adults', BMC Psychiatry, 12, http://dx.doi.org/10.1186/1471-244X-12-191

Ikeda Y; Koeda M; Kim W; Tateno A; Okubo Y; Suzuki H, 2012, 'Caffeine's effects on attentional networks in healthy subjects: A pharmacological functional magnetic resonance imaging study', Journal of Nippon Medical School, 79, pp. 318 - 319, http://dx.doi.org/10.1272/jnms.79.318

Seino S; Yabushita N; Kim MJ; Nemoto M; Jung S; Osuka Y; Okubo Y; Matsuo T; Tanaka K, 2012, 'Comparison of a combination of upper extremity performance measures and usual gait speed alone for discriminating upper extremity functional limitation and disability in older women', Archives of Gerontology and Geriatrics, 55, pp. 486 - 491, http://dx.doi.org/10.1016/j.archger.2011.10.011

Seino S; Kim MJ; Yabushita N; Nemoto M; Jung S; Osuka Y; Okubo Y; Matsuo T; Tanaka K, 2012, 'Is a composite score of physical performance measures more useful than usual gait speed alone in assessing functional status?', Archives of Gerontology and Geriatrics, 55, pp. 392 - 398, http://dx.doi.org/10.1016/j.archger.2011.11.011

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