Select Publications
Book Chapters
2012, 'MicroRNAs in cancer stem cells', in MicroRNA in Cancer, pp. 29 - 41, http://dx.doi.org/10.1007/978-94-007-4655-8_3
,Journal articles
2024, 'snPATHO-seq, a versatile FFPE single-nucleus RNA sequencing method to unlock pathology archives', Communications Biology, 7, http://dx.doi.org/10.1038/s42003-024-07043-2
,2024, 'Abstract C040: Spatial transcriptomics unveils disparities in tumor microenvironment dynamics between breast cancer responders and non-responders', Cancer Research, 84, pp. C040 - C040, http://dx.doi.org/10.1158/1538-7445.tumbody-c040
,2024, 'Spatial landscapes of cancers: insights and opportunities', Nature Reviews Clinical Oncology, 21, pp. 660 - 674, http://dx.doi.org/10.1038/s41571-024-00926-7
,2024, 'Single-cell spatial multiomics reveals tumor microenvironment vulnerabilities in cancer resistance to immunotherapy', Cell Reports, 43, http://dx.doi.org/10.1016/j.celrep.2024.114392
,2024, 'Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response', Science Advances, 10, http://dx.doi.org/10.1126/sciadv.adl1197
,2024, 'Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism', Advanced Science, 11, http://dx.doi.org/10.1002/advs.202307963
,2024, 'Erratum: miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastoma (Molecular Therapy (2022) 30(3) (1119–1134), (S1525001622000041), (10.1016/j.ymthe.2022.01.004))', Molecular Therapy, 32, pp. 2031 - 2033, http://dx.doi.org/10.1016/j.ymthe.2024.05.008
,2024, 'Detailed DNA methylation characterisation of phyllodes tumours identifies a signature of malignancy and distinguishes phyllodes from metaplastic breast carcinoma', Journal of Pathology, 262, pp. 480 - 494, http://dx.doi.org/10.1002/path.6250
,2024, 'Abstract 5480: Single cell and spatial transcriptomic profile of appendiceal tumour peritoneal disease', Cancer Research, 84, pp. 5480 - 5480, http://dx.doi.org/10.1158/1538-7445.am2024-5480
,2024, 'Cancer Evolution: A Multifaceted Affair', Cancer Discovery, 14, pp. 36 - 48, http://dx.doi.org/10.1158/2159-8290.CD-23-0530
,2024, 'Gene-Expression Profiling to Decipher Breast Cancer Inter-and Intratumor Heterogeneity', Cold Spring Harbor Perspectives in Medicine, 14, http://dx.doi.org/10.1101/cshperspect.a041320
,2023, 'Luminal breast cancer identity is determined by loss of glucocorticoid receptor activity', EMBO Molecular Medicine, 15, http://dx.doi.org/10.15252/emmm.202317737
,2023, 'Performance of tumour microenvironment deconvolution methods in breast cancer using single-cell simulated bulk mixtures', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-41385-5
,2023, 'Mitotic Dysregulation at Tumor Initiation Creates a Therapeutic Vulnerability to Combination Anti-Mitotic and Pro-Apoptotic Agents for MYCN-Driven Neuroblastoma', International Journal of Molecular Sciences, 24, http://dx.doi.org/10.3390/ijms242115571
,2023, 'Inhibition of EphA3 Expression in Tumour Stromal Cells Suppresses Tumour Growth and Progression', Cancers, 15, http://dx.doi.org/10.3390/cancers15184646
,2023, 'Reversal of Lactate and PD-1–mediated Macrophage Immunosuppression Controls Growth of PTEN/p53-deficient Prostate Cancer', Clinical Cancer Research, 29, pp. 1952 - 1968, http://dx.doi.org/10.1158/1078-0432.CCR-22-3350
,2023, 'β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling', iScience, 26, http://dx.doi.org/10.1016/j.isci.2023.106477
,2023, 'Abstract 4621: Distinct spatial and molecular maps in the tumour microenvironment of resistant melanoma patients treated with checkpoint inhibitor immunotherapy', Cancer Research, 83, pp. 4621 - 4621, http://dx.doi.org/10.1158/1538-7445.am2023-4621
,2023, 'Phenotypic heterogeneity drives differential disease outcome in a mouse model of triple negative breast cancer', Frontiers in Oncology, 13, http://dx.doi.org/10.3389/fonc.2023.1230647
,2023, '1165P Single cell spatial features of in-transit melanoma associated with patient outcome to immunotherapy', Annals of Oncology, 34, pp. S694 - S694, http://dx.doi.org/10.1016/j.annonc.2023.09.2981
,2023, '11P Targeting stromal cells to reverse immune suppression in triple-negative breast cancer', Annals of Oncology, 34, pp. S190 - S190, http://dx.doi.org/10.1016/j.annonc.2023.09.1514
,2022, 'STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation', Immunity, 55, pp. 2386 - 2404.e8, http://dx.doi.org/10.1016/j.immuni.2022.11.001
,2022, 'Deep whole genome sequencing identifies recurrent genomic alterations in commonly used breast cancer cell lines and patient-derived xenograft models', Breast Cancer Research, 24, http://dx.doi.org/10.1186/s13058-022-01540-0
,2022, 'DNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and immunotherapy response', Nature Communications, 13, http://dx.doi.org/10.1038/s41467-022-34041-x
,2022, 'Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis', Nature Communications, 13, http://dx.doi.org/10.1038/s41467-022-32255-7
,2022, 'Spatial maps of genetically diverse breast cancer cells', Nature, 611, pp. 458 - 459, http://dx.doi.org/10.1038/d41586-022-03560-4
,2022, 'Spatial transcriptomics', Cancer Cell, 40, pp. 895 - 900, http://dx.doi.org/10.1016/j.ccell.2022.08.021
,2022, 'Mapping the cancer cell states conserved across solid tumors', Nature Genetics, 54, pp. 1066 - 1067, http://dx.doi.org/10.1038/s41588-022-01151-7
,2022, 'Publisher Correction: Unchecked oxidative stress in skeletal muscle prevents outgrowth of disseminated tumour cells (Nature Cell Biology, (2022), 24, 4, (538-553), 10.1038/s41556-022-00881-4)', Nature Cell Biology, 24, pp. 1177, http://dx.doi.org/10.1038/s41556-022-00945-5
,2022, 'Unchecked oxidative stress in skeletal muscle prevents outgrowth of disseminated tumour cells', Nature Cell Biology, 24, pp. 538 - 553, http://dx.doi.org/10.1038/s41556-022-00881-4
,2022, 'miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastoma', Molecular Therapy, 30, pp. 1119 - 1134, http://dx.doi.org/10.1016/j.ymthe.2022.01.004
,2021, 'Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis', Genome Medicine, 13, http://dx.doi.org/10.1186/s13073-021-00885-z
,2021, 'Evaluation of FGFR targeting in breast cancer through interrogation of patient-derived models', Breast Cancer Research, 23, http://dx.doi.org/10.1186/s13058-021-01461-4
,2021, 'Identification of DNA methylation biomarkers with potential to predict response to neoadjuvant chemotherapy in triple-negative breast cancer', Clinical Epigenetics, 13, http://dx.doi.org/10.1186/s13148-021-01210-6
,2021, 'Spatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions', Nature Communications, 12, http://dx.doi.org/10.1038/s41467-021-26271-2
,2021, 'Deep whole genome sequencing identifies recurrent genomic alterations in commonly-used breast cancer cell lines and patient derived xenograft models', , http://dx.doi.org/10.21203/rs.3.rs-859624/v1
,2021, 'A single-cell and spatially resolved atlas of human breast cancers', Nature Genetics, 53, pp. 1334 - 1347, http://dx.doi.org/10.1038/s41588-021-00911-1
,2021, 'Best practices for spatial profiling for breast cancer research with the GeoMx® digital spatial profiler', Cancers, 13, http://dx.doi.org/10.3390/cancers13174456
,2021, 'Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease', Immunity, 54, pp. 1883 - 1900.e5, http://dx.doi.org/10.1016/j.immuni.2021.07.007
,2021, 'Single-cell advances in stromal-leukocyte interactions in cancer', Immunological Reviews, 302, pp. 286 - 298, http://dx.doi.org/10.1111/imr.12976
,2021, 'Chromatin immunoprecipitation of transcription factors and histone modifications in Comma-Dβ mammary epithelial cells', STAR Protocols, 2, http://dx.doi.org/10.1016/j.xpro.2021.100514
,2021, 'Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB', iScience, 24, http://dx.doi.org/10.1016/j.isci.2021.102072
,2021, 'The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer', Nature Medicine, 27, pp. 310 - 320, http://dx.doi.org/10.1038/s41591-020-01168-7
,2021, 'A MXI1-NUTM1 fusion protein with MYC-like activity suggests a novel oncogenic mechanism in a subset of NUTM1-rearranged tumors', Laboratory Investigation, 101, pp. 26 - 37, http://dx.doi.org/10.1038/s41374-020-00484-3
,2021, 'DNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and in response to immunotherapy', , http://dx.doi.org/10.1101/2021.01.11.426174
,2020, 'Tumour stroma ratio assessment using digital image analysis predicts survival in triple negative and luminal breast cancer', Cancers, 12, pp. 1 - 14, http://dx.doi.org/10.3390/cancers12123749
,2020, 'Stromal cell diversity associated with immune evasion in human triple-negative breast cancer', EMBO Journal, 39, pp. embj2019104063, http://dx.doi.org/10.15252/embj.2019104063
,2020, 'Targeting the id1-kif11 axis in triple-negative breast cancer using combination therapy', Biomolecules, 10, pp. 1 - 15, http://dx.doi.org/10.3390/biom10091295
,2020, 'MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer', Breast Cancer Research, 22, pp. 87, http://dx.doi.org/10.1186/s13058-020-01318-2
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