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Select Publications
2019, 'IRF2 transcriptionally induces GSDMD expression for pyroptosis', Science Signaling, 12, http://dx.doi.org/10.1126/scisignal.aax4917
,2019, 'DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns', Cancer Cell, 35, pp. 297 - 314.e8, http://dx.doi.org/10.1016/j.ccell.2019.01.004
,2019, 'A divergent transcriptional landscape underpins the development and functional branching of MAIT cells', Science Immunology, 4, http://dx.doi.org/10.1126/sciimmunol.aay6039
,2019, 'Phospho-tuning immunity through Denisovan, modern human and mouse TNFAIP3 gene variants', bioRxiv, pp. 589507, http://dx.doi.org/10.1101/589507
,2019, 'Oligoclonal lymphocytosis and cytokine derangement in a case of severe adverse drug reaction', Pathology, 51, pp. S131 - S131, http://dx.doi.org/10.1016/j.pathol.2018.12.378
,2019, 'The Australian Exceptional Responders Program: A national collaboration', Annals of Oncology, 30, pp. v794 - v795, http://dx.doi.org/10.1093/annonc/mdz268.104
,2018, 'STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles', Scientific Reports, 8, pp. 3529, http://dx.doi.org/10.1038/s41598-018-21389-8
,2018, 'Molecular Profiling and Clonal Tracking of Secreted Rheumatoid Factors in Primary Sjögren's Syndrome', Arthritis and Rheumatology, 70, pp. 1617 - 1625, http://dx.doi.org/10.1002/art.40539
,2018, 'B-cell receptor reconstruction from single-cell RNA-seq with VDJPuzzle', Bioinformatics, 34, pp. 2846 - 2847, http://dx.doi.org/10.1093/BIOINFORMATICS/BTY171
,2018, 'Understanding Immune Tolerance of Cancer: Re-Purposing Insights from Fetal Allografts and Microbes', BioEssays, 40, http://dx.doi.org/10.1002/bies.201800050
,2018, 'The Ubiquitin Ligase Adaptor NDFIP1 Selectively Enforces a CD8+ T Cell Tolerance Checkpoint to High-Dose Antigen', Cell Reports, 24, pp. 577 - 584, http://dx.doi.org/10.1016/j.celrep.2018.06.060
,2018, 'Indirect presentation in the thymus limits naive and regulatory T-cell differentiation by promoting deletion of self-reactive thymocytes', Immunology, 154, pp. 522 - 532, http://dx.doi.org/10.1111/imm.12904
,2018, 'αβ T-cell receptors with a central CDR3 cysteine are enriched in CD8αα intraepithelial lymphocytes and their thymic precursors', Immunology and Cell Biology, 96, pp. 553 - 561, http://dx.doi.org/10.1111/imcb.12047
,2018, 'Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination', Science, 360, pp. 223 - 226, http://dx.doi.org/10.1126/science.aao3859
,2018, 'High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes', , http://dx.doi.org/10.1101/424945
,2017, 'A mutation in the viral sensor 2’-5’-oligoadenylate synthetase 2 causes failure of lactation', PLoS Genetics, 13, pp. e1007072, http://dx.doi.org/10.1371/journal.pgen.1007072
,2017, 'Structural basis of antigen recognition: Crystal structure of duck egg lysozyme', Acta Crystallographica Section D: Structural Biology, 73, pp. 910 - 920, http://dx.doi.org/10.1107/S2059798317013730
,2017, 'Murine LRBA deficiency causes CTLA-4 deficiency in Tregs without progression to immune dysregulation', Immunology and Cell Biology, 95, pp. 775 - 788, http://dx.doi.org/10.1038/icb.2017.50
,2017, 'Systems-guided forward genetic screen reveals a critical role of the replication stress response protein ETAA1 in T cell clonal expansion', Proceedings of the National Academy of Sciences of the United States of America, 114, pp. E5216 - E5225, http://dx.doi.org/10.1073/pnas.1705795114
,2017, 'Euglycaemic diabetic ketoacidosis in patients using sodium-glucose co-transporter 2 inhibitors', Internal Medicine Journal, 47, pp. 701 - 704, http://dx.doi.org/10.1111/imj.13442
,2017, 'IL-2 prevents deletion of developing T-regulatory cells in the thymus', Cell Death and Differentiation, 24, pp. 1007 - 1016, http://dx.doi.org/10.1038/cdd.2017.38
,2017, 'Dedicator of cytokinesis 8-deficient CD4(+) T cells are biased to a T(H)2 effector fate at the expense of T(H)1 and T(H)17 cells', JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 139, pp. 933 - 949, http://dx.doi.org/10.1016/j.jaci.2016.07.016
,2017, 'Dedicator of cytokinesis 8–deficient CD4+ T cells are biased to a T
2017, 'Low dose prednisolone and insulin sensitivity differentially affect arterial stiffness and endothelial function: An open interventional and cross-sectional study', Atherosclerosis, 258, pp. 34 - 39, http://dx.doi.org/10.1016/j.atherosclerosis.2017.01.033
,2017, 'Muscle sympathetic nerve activity is associated with liver insulin sensitivity in obese non-diabetic men', Frontiers in Physiology, 8, pp. 101, http://dx.doi.org/10.3389/fphys.2017.00101
,2017, 'Synergistic cooperation and crosstalk between MYD88L265P and mutations that dysregulate CD79B and surface IgM', Journal of Experimental Medicine, 214, pp. 2759 - 2776, http://dx.doi.org/10.1084/jem.20161454
,2017, 'Up-regulation of LFA-1 allows liver-resident memory T cells to patrol and remain in the hepatic sinusoids', Science Immunology, 2, http://dx.doi.org/10.1126/sciimmunol.aaj1996
,2017, 'B-cell receptor reconstruction from single-cell RNA-seq with VDJPuzzle', , http://dx.doi.org/10.1101/181156
,2016, 'Pharmacokinetics of Metformin in Patients Receiving Regular Hemodiafiltration', American Journal of Kidney Diseases, 68, pp. 990 - 992, http://dx.doi.org/10.1053/j.ajkd.2016.08.017
,2016, 'Trends in metformin utilisation and dose appropriateness in Australia', European Journal of Clinical Pharmacology, 72, pp. 1489 - 1496, http://dx.doi.org/10.1007/s00228-016-2117-y
,2016, 'CD45-mediated control of TCR tuning in naïve and memory CD8+ T cells', Nature Communications, 7, pp. 13373, http://dx.doi.org/10.1038/ncomms13373
,2016, 'IgD attenuates the IgM-induced anergy response in transitional and mature B cells', Nature Communications, 7, http://dx.doi.org/10.1038/ncomms13381
,2016, 'A review of maturity onset diabetes of the young (MODY) and challenges in the management of glucokinase-MODY', Medical Journal of Australia, 205, pp. 480 - 485, http://dx.doi.org/10.5694/MJA16.00458
,2016, 'Fibroblast growth factor-1 (FGF-1) promotes adipogenesis by downregulation of carboxypeptidase A4 (CPA4)–a negative regulator of adipogenesis implicated in the modulation of local and systemic insulin sensitivity', Growth Factors, 34, pp. 210 - 216, http://dx.doi.org/10.1080/08977194.2017.1285764
,2016, 'Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle', Molecular Metabolism, 5, pp. 1083 - 1091, http://dx.doi.org/10.1016/j.molmet.2016.09.002
,2016, 'A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage', Nature Immunology, 17, pp. 1300 - 1311, http://dx.doi.org/10.1038/ni.3565
,2016, 'A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton', Journal of Clinical Investigation, 126, pp. 3837 - 3851, http://dx.doi.org/10.1172/JCI85774
,2016, 'A Novel Mutation in Nucleoporin 35 Causes Murine Degenerative Colonic Smooth Muscle Myopathy', American Journal of Pathology, 186, pp. 2254 - 2261, http://dx.doi.org/10.1016/j.ajpath.2016.04.016
,2016, 'TCR transgenic mice reveal the impact of type 1 diabetes loci on early and late disease checkpoints', Immunology and Cell Biology, 94, pp. 709 - 713, http://dx.doi.org/10.1038/icb.2016.27
,2016, 'Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization', Journal of Experimental Medicine, 213, pp. 1255 - 1265, http://dx.doi.org/10.1084/jem.20151978
,2016, 'Temporal HbA1c patterns amongst patients with type 2 diabetes referred for specialist care: Data from the S4S-DINGO-Diabetes Informatics Group', Diabetes Research and Clinical Practice, 116, pp. 159 - 164, http://dx.doi.org/10.1016/j.diabres.2016.04.006
,2016, 'Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes', Nature Genetics, 48, pp. 519 - 527, http://dx.doi.org/10.1038/ng.3531
,2016, 'Heterogeneity of Human Neutrophil CD177 Expression Results from CD177P1 Pseudogene Conversion', PLoS Genetics, 12, pp. e1006067, http://dx.doi.org/10.1371/journal.pgen.1006067
,2016, 'Erratum: Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation (Nature (2015) 528 (370-375) (DOI:10.1038/nature16165))', Nature, 532, pp. 402, http://dx.doi.org/10.1038/nature16541
,2016, 'Brown Adipose Tissue Exhibits a Glucose-Responsive Thermogenic Biorhythm in Humans', Cell Metabolism, 23, pp. 602 - 609, http://dx.doi.org/10.1016/j.cmet.2016.02.007
,2016, 'A timeline demarcating two waves of clonal deletion and Foxp3 upregulation during thymocyte development', Immunology and Cell Biology, 94, pp. 357 - 366, http://dx.doi.org/10.1038/icb.2015.95
,2016, 'Skeletal muscle and plasma lipidomic signatures of insulin resistance and overweight/obesity in humans', Obesity, 24, pp. 908 - 916, http://dx.doi.org/10.1002/oby.21448
,2016, 'DeepSNVMiner: A sequence analysis tool to detect emergent, rare mutations in subsets of cell populations', PeerJ, 2016, http://dx.doi.org/10.7717/peerj.2074
,2016, 'Inhibiting TLR9 and other UNC93B1-dependent TLRs paradoxically increases accumulation of MYD88L265P plasmablasts in vivo', Blood, 128, pp. 1604 - 1608, http://dx.doi.org/10.1182/blood-2016-03-708065
,2016, 'Synchronous Nesidioblastosis, Endocrine Microadenoma, and Intraductal Papillary Mucinous Neoplasia in a Man Presenting with Hyperinsulinemic Hypoglycemia', Pancreas, 45, pp. 154 - 159, http://dx.doi.org/10.1097/MPA.0000000000000430
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