By Professor David Simon Ziegler

Journal articles

Hetherington K; Wakefield CE; Kunalan KPK; Donoghoe MW; McGill BC; Fardell JE; Daly R; Deyell RJ; Ziegler DS, 2022, 'Quality of Life (QoL) of Children and Adolescents Participating in a Precision Medicine Trial for High-Risk Childhood Cancer', Cancers, 14, http://dx.doi.org/10.3390/cancers14215310

Gargett T; Ebert LM; Truong NTH; Kollis PM; Sedivakova K; Yu W; Yeo ECF; Wittwer NL; Gliddon BL; Tea MN; Ormsby R; Poonnoose S; Nowicki J; Vittorio O; Ziegler DS; Pitson SM; Brown MP, 2022, 'GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma', Journal for ImmunoTherapy of Cancer, 10, http://dx.doi.org/10.1136/jitc-2022-005187

Tsai JW; Cejas P; Wang DK; Patel S; Wu DW; Arounleut P; Wei X; Zhou N; Syamala S; Dubois FPB; Crane A; Pelton K; Vogelzang J; Sousa C; Baguette A; Chen X; Condurat AL; Dixon-Clarke SE; Zhou KN; Lu SD; Gonzalez EM; Chacon MS; Digiacomo JJ; Kumbhani R; Novikov D; Hunter J; Tsoli M; Ziegler DS; Dirksen U; Jager N; Balasubramanian GP; Kramm CM; Nathrath M; Bielack S; Baker SJ; Zhang J; McFarland JM; Getz G; Aguet F; Jabado N; Witt O; Pfister SM; Ligon KL; Hovestadt V; Kleinman CL; Long H; Jones DTW; Bandopadhayay P; Phoenix TN, 2022, 'FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits', Cancer Research, 82, pp. 2980 - 3001, http://dx.doi.org/10.1158/0008-5472.CAN-22-0671

Deblois S; Zhu L; Mastropasqua B; Thibaudeau S; Ziegler D; Pomp A, 2022, 'The clinical effectiveness and safety of intravenous unfractionated heparin following digital replantation and revascularization: A narrative systematic review', Microsurgery, 42, pp. 622 - 630, http://dx.doi.org/10.1002/micr.30895

Lazow MA; Nievelstein MT; Lane A; Bandopadhayhay P; DeWire-Schottmiller M; Fouladi M; Glod JW; Greiner RJ; Hoffman LM; Hummel TR; Kilburn L; Leary S; Minturn JE; Packer R; Ziegler DS; Chaney B; Black K; de Blank P; Leach JL, 2022, 'Volumetric endpoints in diffuse intrinsic pontine glioma: p correlations in the International DIPG/DMG Registry', Neuro-Oncology, 24, pp. 1598 - 1608, http://dx.doi.org/10.1093/neuonc/noac037

Sacks E; Finlayson K; Brizuela V; Crossland N; Ziegler D; Sauvé C; Langlois ÉV; Javadi D; Downe S; Bonet M, 2022, 'Factors that influence uptake of routine postnatal care: Findings on women’s perspectives from a qualitative evidence synthesis', PLoS ONE, 17, http://dx.doi.org/10.1371/journal.pone.0270264

Hunter JD; Robertson EG; Hetherington K; Ziegler DS; Marshall GM; Kirk J; Marron JM; Denburg AE; Barlow-Stewart K; Warby M; Tucker KM; Lee BM; O’Brien TA; Wakefield CE; O'Brien T, 2022, 'What’s in a Name? Parents’ and Healthcare Professionals’ Preferred Terminology for Pathogenic Variants in Childhood Cancer Predisposition Genes', Journal of Personalized Medicine, 12, pp. 1327, http://dx.doi.org/10.3390/jpm12081327

Lamoureux A-A; Fisher M; Lemelle L; Pfaff E; Kramm C; De Wilde B; Kazanowska B; Hutter C; Pfister SM; Sturm D; Jones D; Orbach D; Pierron G; Raskin S; Drilon A; Diamond E; Harada G; Zapotocky M; Ellezam B; Weil AG; Venne D; Barritault M; Leblond P; Coltin H; Hammad R; Tabori U; Hawkins C; Hansford JR; Meyran D; Erker C; McFadden K; Sato M; Gottardo NG; Dholaria H; Nørøxe DS; Goto H; Ziegler DS; Lin FY; Parsons DW; Lindsay H; Wong T-T; Liu Y-L; Wu K-S; Franson AF; Hwang E; Aguilar-Bonilla A; Cheng S; Cacciotti C; Massimino M; Schiavello E; Wood P; Hoffman LM; Cappellano A; Lassaletta A; Van Damme A; Llort A; Gerber NU; Ceruso MS; Bendel AE; Skrypek M; Hamideh D; Mushtaq N; Walter A; Jabado N; Alsahlawi A; Farmer J-P; Abadi CC; Mueller S; Mazewski C; Aguilera D; Robison N; O’Halloran K; Abbou S; Berlanga P; Geoerger B; Øra I; Moertel CL; Razis ED; Vernadou A; Doz F; Laetsch TW; Perreault S, 2022, 'HGG-11. Clinical characteristics and clinical evolution of a large cohort of pediatric patients with primary central nervous system (CNS) tumors and tropomyosin receptor kinase (TRK) fusion.', Neuro-Oncology, 24, pp. i61 - i62, http://dx.doi.org/10.1093/neuonc/noac079.226

Daniel P; Sun C; Koptyra M; Drinkwater C; Chew N; Bradshaw G; Loi M; Shi C; Tourchi M; Parackal S; Chong WC; Fernando D; Adjumain S; Nguyen H; Habarakada D; Sooraj D; Crombie D; Zhukova N; Jones C; Rubens J; Raabe E; Vinci M; Dun M; Ludlow L; Nazarian J; Fletcher J; Ekert P; Ziegler D; Loh AHP; Low SYY; Monje M; Neeman N; Williams B; Resnick A; Gough D; Cain J; Firestein R, 2022, 'MODL-17. The Childhood Brain Cancer Cell Line Atlas: A Resource for Biomarker Identification and Therapeutic Development', Neuro-Oncology, 24, pp. i172 - i172, http://dx.doi.org/10.1093/neuonc/noac079.640

Kong BY; Carter C; Nowak AK; Hovey E; Lwin Z; Haghighi N; Gan HK; Sim HW; Ziegler DS; Barton K; Parkinson J; Leonard R; Khasraw M; Foote M, 2022, 'Barriers and potential solutions to international collaboration in neuro-oncology clinical trials: Challenges from the Australian perspective', Asia-Pacific Journal of Clinical Oncology, 18, pp. 259 - 266, http://dx.doi.org/10.1111/ajco.13606

Doz F; Van Tilburg CM; Geoerger B; Højgaard M; Øra I; Boni V; Capra M; Chisholm J; Chung HC; Dubois SG; Gallego-Melcon S; Gerber NU; Goto H; Grilley-Olson JE; Hansford JR; Hong DS; Italiano A; Kang HJ; Nysom K; Thorwarth A; Stefanowicz J; Tahara M; Ziegler DS; Gavrilovic IT; Norenberg R; Dima L; De La Cuesta E; Laetsch TW; Drilon A; Perreault S, 2022, 'Efficacy and safety of larotrectinib in TRK fusion-positive primary central nervous system tumors', Neuro-Oncology, 24, pp. 997 - 1007, http://dx.doi.org/10.1093/neuonc/noab274

Lazow MA; Fuller C; Dewire M; Lane A; Bandopadhayay P; Bartels U; Bouffet E; Cheng S; Cohen KJ; Cooney TM; Coven SL; Dholaria H; Diez B; Dorris K; El-Ayadi M; El-Sheikh A; Fisher PG; Fonseca A; Garcia Lombardi M; Greiner RJ; Goldman S; Gottardo N; Gururangan S; Hansford JR; Hassall T; Hawkins C; Kilburn L; Koschmann C; Leary SE; Ma J; Minturn JE; Monje-Deisseroth M; Packer R; Samson Y; Sandler ES; Sevlever G; Tinkle CL; Tsui K; Wagner LM; Zaghloul M; Ziegler DS; Chaney B; Black K; Asher A; Drissi R; Fouladi M; Jones BV; Leach JL, 2022, 'Accuracy of central neuro-imaging review of DIPG compared with histopathology in the International DIPG Registry', Neuro-Oncology, 24, pp. 821 - 833, http://dx.doi.org/10.1093/neuonc/noab245

Pommert L; Schafer ES; Malvar J; Gossai N; Florendo E; Pulakanti K; Heimbruch K; Stelloh C; Chi YY; Sposto R; Rao S; Huynh VT; Brown P; Chang BH; Colace SI; Hermiston ML; Heym K; Hutchinson RJ; Kaplan JA; Mody R; O'Brien TA; Place AE; Shaw PH; Ziegler DS; Wayne A; Bhojwani D; Burke MJ, 2022, 'Decitabine and vorinostat with FLAG chemotherapy in pediatric relapsed/refractory AML: Report from the therapeutic advances in childhood leukemia and lymphoma (TACL) consortium', American Journal of Hematology, 97, pp. 613 - 622, http://dx.doi.org/10.1002/ajh.26510

Lau LMS; Mayoh C; Xie J; Barahona P; MacKenzie KL; Wong M; Kamili A; Tsoli M; Failes TW; Kumar A; Mould EVA; Gifford A; Chow SO; Pinese M; Fletcher JI; Arndt GM; Khuong-Quang DA; Wadham C; Batey D; Eden G; Trebilcock P; Joshi S; Alfred S; Gopalakrishnan A; Khan A; Grebert Wade D; Strong PA; Manouvrier E; Morgan LT; Span M; Lim JY; Cadiz R; Ung C; Thomas DM; Tucker KM; Warby M; McCowage GB; Dalla-Pozza L; Byrne JA; Saletta F; Fellowes A; Fox SB; Norris MD; Tyrrell V; Trahair TN; Lock RB; Cowley MJ; Ekert PG; Haber M; Ziegler DS; Marshall GM; Trahair T, 2022, 'In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer', EMBO Molecular Medicine, 14, pp. e14608, http://dx.doi.org/10.15252/emmm.202114608

Upton DH; Ung C; George SM; Tsoli M; Kavallaris M; Ziegler DS, 2022, 'Challenges and opportunities to penetrate the blood-brain barrier for brain cancer therapy', Theranostics, 12, pp. 4734 - 4752, http://dx.doi.org/10.7150/THNO.69682

Erker C; Lane A; Chaney B; Leary S; Minturn JE; Bartels U; Packer RJ; Dorris K; Gottardo NG; Warren KE; Broniscer A; Kieran MW; Zhu X; White P; Dexheimer PJ; Black K; Asher A; Dewire M; Hansford JR; Gururangan S; Nazarian J; Ziegler DS; Sandler E; Bartlett A; Goldman S; Shih CS; Hassall T; Dholaria H; Bandopadhayay P; Samson Y; Monje M; Fisher PG; Dodgshun A; Parkin S; Chintagumpala M; Tsui K; Gass D; Larouche V; Broxson E; Garcia Lombardi M; Wang SS; Ma J; Hawkins C; Hamideh D; Wagner L; Koschmann C; Fuller C; Drissi R; Jones BV; Leach J; Fouladi M, 2022, 'Characteristics of patients ≥10 years of age with diffuse intrinsic pontine glioma: a report from the International DIPG/DMG Registry', Neuro-Oncology, 24, pp. 141 - 152, http://dx.doi.org/10.1093/neuonc/noab140

Das A; Sudhaman S; Morgenstern D; Coblentz A; Chung J; Stone SC; Alsafwani N; Liu ZA; Karsaneh OAA; Soleimani S; Ladany H; Chen D; Zatzman M; Cabric V; Nobre L; Bianchi V; Edwards M; Sambira Nahum LC; Ercan AB; Nabbi A; Constantini S; Dvir R; Yalon-Oren M; Campino GA; Caspi S; Larouche V; Reddy A; Osborn M; Mason G; Lindhorst S; Bronsema A; Magimairajan V; Opocher E; De Mola RL; Sabel M; Frojd C; Sumerauer D; Samuel D; Cole K; Chiaravalli S; Massimino M; Tomboc P; Ziegler DS; George B; Van Damme A; Hijiya N; Gass D; McGee RB; Mordechai O; Bowers DC; Laetsch TW; Lossos A; Blumenthal DT; Sarosiek T; Yen LY; Knipstein J; Bendel A; Hoffman LM; Luna-Fineman S; Zimmermann S; Scheers I; Nichols KE; Zapotocky M; Hansford JR; Maris JM; Dirks P; Taylor MD; Kulkarni AV; Shroff M; Tsang DS; Villani A; Xu W; Aronson M; Durno C; Shlien A; Malkin D; Getz G; Maruvka YE; Ohashi PS; Hawkins C; Pugh TJ; Bouffet E; Tabori U, 2022, 'Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency', Nature Medicine, 28, pp. 125 - 135, http://dx.doi.org/10.1038/s41591-021-01581-6

Fischer M; Moreno L; Ziegler DS; Marshall LV; Zwaan CM; Irwin MS; Casanova M; Sabado C; Wulff B; Stegert M; Wang L; Hurtado FK; Branle F; Geoerger B; Schulte JH, 2021, 'Ceritinib in paediatric patients with anaplastic lymphoma kinase-positive malignancies: an open-label, multicentre, phase 1, dose-escalation and dose-expansion study', The Lancet Oncology, 22, pp. 1764 - 1776, http://dx.doi.org/10.1016/S1470-2045(21)00536-2

Manoharan N; Ajuyah P; Senapati A; Wong M; Mullins A; Rodriguez M; Doyle H; McCowage G; Lau LMS; Ekert PG; Ziegler DS, 2021, 'Diffuse leptomeningeal glioneuronal tumour (DLGNT) in children: the emerging role of genomic analysis', Acta Neuropathologica Communications, 9, http://dx.doi.org/10.1186/s40478-021-01248-w

Khan A; Gamble LD; Upton DH; Ung C; Yu DMT; Ehteda A; Pandher R; Mayoh C; Hébert S; Jabado N; Kleinman CL; Burns MR; Norris MD; Haber M; Tsoli M; Ziegler DS, 2021, 'Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas', Nature Communications, 12, pp. 971, http://dx.doi.org/10.1038/s41467-021-20896-z

Nagabushan S; Lau LMS; Barahona P; Wong M; Sherstyuk A; Marshall GM; Tyrrell V; Wegner EA; Ekert PG; Cowley MJ; Mayoh C; Trahair TN; Crowe P; Anazodo A; Ziegler DS, 2021, 'Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor', npj Precision Oncology, 5, http://dx.doi.org/10.1038/s41698-021-00145-8

Goudie C; Witkowski L; Cullinan N; Reichman L; Schiller I; Tachdjian M; Armstrong L; Blood KA; Brossard J; Brunga L; Cacciotti C; Caswell K; Cellot S; Clark ME; Clinton C; Coltin H; Felton K; Fernandez CV; Fleming AJ; Fuentes-Bolanos N; Gibson P; Grant R; Hammad R; Harrison LW; Irwin MS; Johnston DL; Kane S; Lafay-Cousin L; Lara-Corrales I; Larouche V; Mathews N; Meyn MS; Michaeli O; Perrier R; Pike M; Punnett A; Ramaswamy V; Say J; Somers G; Tabori U; Thibodeau ML; Toupin AK; Tucker KM; Van Engelen K; Vairy S; Waespe N; Warby M; Wasserman JD; Whitlock JA; Sinnett D; Jabado N; Nathan PC; Shlien A; Kamihara J; Deyell RJ; Ziegler DS; Nichols KE; Dendukuri N; Malkin D; Villani A; Foulkes WD, 2021, 'Performance of the McGill Interactive Pediatric OncoGenetic Guidelines for Identifying Cancer Predisposition Syndromes', JAMA Oncology, 7, pp. 1806 - 1814, http://dx.doi.org/10.1001/jamaoncol.2021.4536

Hayden E; Holliday H; Lehmann R; Khan A; Tsoli M; Rayner BS; Ziegler DS, 2021, 'Therapeutic targets in diffuse midline gliomas—an emerging landscape', Cancers, 13, http://dx.doi.org/10.3390/cancers13246251

Doz F; van Tilburg CM; Geoerger B; Nysom K; Øra I; Boni V; Chisholm J; Chung HC; DuBois SG; Melcón SG; Gerber NU; Goto H; Grilley-Olsen JE; Hansford JR; Hong DS; Italiano A; Kang HJ; Capra M; Schulte JH; Stefanowicz J; Tahara M; Ziegler DS; Gavrilovic IT; Norenberg R; Dima L; De La Cuesta E; Laetsch TW; Drilon A; Perreault S, 2021, 'CTNI-58. EFFICACY AND SAFETY OF LAROTRECTINIB IN ADULT AND PEDIATRIC PATIENTS WITH TROPOMYOSIN RECEPTOR KINASE (TRK) FUSION-POSITIVE PRIMARY CENTRAL NERVOUS SYSTEM (CNS) TUMORS', Neuro-Oncology, 23, pp. vi73 - vi74, http://dx.doi.org/10.1093/neuonc/noab196.283

Lazow M; Nievelstein M; Lane A; Bandopadhayay P; DeWire-Schottmiller M; Fouladi M; Glod J; Greiner R; Hoffman L; Hummel T; Kilburn L; Leary S; Minturn J; Packer R; Ziegler DS; Chaney B; Black K; de Blank P; Leach J, 2021, 'NIMG-11. VOLUMETRIC ENDPOINTS IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG): COMPARISON TO CROSS-SECTIONAL MEASURES AND CORRELATION WITH OUTCOMES', Neuro-Oncology, 23, pp. vi129 - vi130, http://dx.doi.org/10.1093/neuonc/noab196.511

Burke MJ; Ziegler DS; Bautista F; Attarbaschi A; Gore L; Locatelli F; O'Brien MM; Pauly M; Obreja M; Morris CL; Baruchel A, 2021, 'Phase 1b Study of Carfilzomib in Combination with Induction Chemotherapy in Children with Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL)', Blood, 138, pp. 1235 - 1235, http://dx.doi.org/10.1182/blood-2021-147588

Ziegler DS; Huynh V; Burke MJ; Gore L; Locatelli F; O'Brien MM; Kim C; Obreja M; Morris CL; Baruchel A, 2021, 'Phase 2 Study of Carfilzomib in Combination with Induction Chemotherapy in Children with Relapsed or Refractory (R/R) Acute Lymphoblastic Leukemia (ALL)', Blood, 138, pp. 4403 - 4403, http://dx.doi.org/10.1182/blood-2021-153865

Khan S; Solano-Paez P; Suwal T; Lu M; Al-Karmi S; Ho B; Mumal I; Shago M; Hoffman LM; Dodgshun A; Nobusawa S; Tabori U; Bartels U; Ziegler DS; Hansford JR; Ramaswamy V; Hawkins C; Dufour C; André N; Bouffet E; Huang A; Gonzalez CV A; Stephens D; Leary S; Marrano P; Fonseca A; Thacker N; Li BK; Lindsay HB; Lassaletta A; Bendel AE; Moertel C; Morales La Madrid A; Santa-Maria V; Lavarino C; Rivas E; Perreault S; Ellezam B; Weil AG; Jabado N; Oviedo A; Yalon-Oren M; Amariglio L; Toledano H; Dvir R; Loukides J; Van Meter TE; Nakamura H; Wong TT; Wu KS; Cheng CJ; Ra YS; La Spina M; Massimi L; Buccoliero AM; Reddy A; Li R; Gillespie GY; Adamek D; Fangusaro J; Scharnhorst D; Torkildson J; Johnston D; Michaud J; LafayCousin L; Chan J; Van Landeghem F; Wilson B; Camelo-Piragua S; Kabbara N; Boutarbouch M; Hanson D; Jacobsen C; Wright K; Vibhakar R; Levy JM; Wang Y; Catchpoole D; Gerber N; Grotzer MA; Shen V; Plant A; Dunham C; Joao Gil da Costa M; Ramanujachar R; Raabe E; Rubens J; Phillips J; Gupta N; Demir HA; Dahl C; Jorgensen M; Hwang EI; Packer RJ; Smith A; Tan E; Low S; Lu JQ; Ng HK; Kresak JL, 2021, 'Clinical phenotypes and prognostic features of embryonal tumours with multi-layered rosettes: a Rare Brain Tumor Registry study', The Lancet Child and Adolescent Health, 5, pp. 800 - 813, http://dx.doi.org/10.1016/S2352-4642(21)00245-5

Meyran D; Terry RL; Zhu JJ; Haber M; Ziegler DS; Ekert PG; Trapani JA; Darcy PK; Neeson PJ, 2021, 'Early-phenotype CAR-T cells for the treatment of pediatric cancers', Annals of Oncology, 32, pp. 1366 - 1380, http://dx.doi.org/10.1016/j.annonc.2021.07.018

Terry RL; Meyran D; Fleuren EDG; Mayoh C; Zhu J; Omer N; Ziegler DS; Haber M; Darcy PK; Trapani JA; Neeson PJ; Ekert PG, 2021, 'Chimeric antigen receptor t cell therapy and the immunosuppressive tumor microenvironment in pediatric sarcoma', Cancers, 13, pp. 4704, http://dx.doi.org/10.3390/cancers13184704

Durno C; Ercan AB; Bianchi V; Edwards M; Aronson M; Galati M; Atenafu EG; Abebe-Campino G; Al-Battashi A; Alharbi M; Azad VF; Baris HN; Basel D; Bedgood R; Bendel A; Ben-Shachar S; Blumenthal DT; Blundell M; Bornhorst M; Bronsema A; Cairney E; Rhode S; Caspi S; Chamdin A; Chiaravalli S; Constantini S; Crooks B; Das A; Dvir R; Farah R; Foulkes WD; Frenkel Z; Gallinger B; Gardner S; Gass D; Ghalibafian M; Gilpin C; Goldberg Y; Goudie C; Hamid SA; Hampel H; Hansford JR; Harlos C; Hijiya N; Hsu S; Kamihara J; Kebudi R; Knipstein J; Koschmann C; Kratz C; Larouche V; Lassaletta A; Lindhorst S; Ling SC; Link MP; De Mola RL; Luiten R; Lurye M; Maciaszek JL; MagimairajanIssai V; Maher OM; Massimino M; McGee RB; Mushtaq N; Mason G; Newmark M; Nicholas G; Nichols KE; Nicolaides T; Opocher E; Osborn M; Oshrine B; Pearlman R; Pettee D; Rapp J; Rashid M; Reddy A; Reichman L; Remke M; Robbins G; Roy S; Sabel M; Samuel D; Scheers I; Schneider KW; Sen S; Stearns D; Sumerauer D; Swallow C; Taylor L; Thomas G; Toledano H; Tomboc P; Van Damme A; Winer I; Yalon M; Yen LY; Zapotocky M; Zelcer S; Ziegler DS, 2021, 'Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance', Journal of Clinical Oncology, 39, pp. 2779 - 2790, http://dx.doi.org/10.1200/JCO.20.02636

Michniewicz F; Saletta F; Rouaen JRC; Hewavisenti RV; Mercatelli D; Cirillo G; Giorgi FM; Trahair T; Ziegler D; Vittorio O, 2021, 'Copper: An Intracellular Achilles’ Heel Allowing the Targeting of Epigenetics, Kinase Pathways, and Cell Metabolism in Cancer Therapeutics', ChemMedChem, 16, pp. 2315 - 2329, http://dx.doi.org/10.1002/cmdc.202100172

Xiao L; Somers K; Murray J; Pandher R; Karsa M; Ronca E; Bongers A; Terry R; Ehteda A; Gamble LD; Issaeva N; Leonova KI; O’Connor A; Mayoh C; Venkat P; Quek H; Brand J; Kusuma FK; Pettitt JA; Mosmann E; Kearns A; Eden G; Alfred S; Allan S; Zhai L; Kamili A; Gifford AJ; Carter DR; Henderson MJ; Fletcher JI; Marshall G; Johnstone RW; Cesare AJ; Ziegler DS; Gudkov AV; Gurova KV; Norris MD; Haber M, 2021, 'Dual targeting of chromatin stability by the curaxin CBL0137 and histone deacetylase inhibitor panobinostat shows significant preclinical efficacy in neuroblastoma', Clinical Cancer Research, 27, pp. 4338 - 4352, http://dx.doi.org/10.1158/1078-0432.CCR-20-2357

Hau P; Frappaz D; Hovey E; McCabe MG; Pajtler KW; Wiestler B; Seidel C; Combs SE; Dirven L; Klein M; Anazodo A; Hattingen E; Hofer S; Pfister SM; Zimmer C; Kortmann RD; Sunyach MP; Tanguy R; Effeney R; von Deimling A; Sahm F; Rutkowski S; Berghoff AS; Franceschi E; Pineda E; Beier D; Peeters E; Gorlia T; Vanlancker M; Bromberg JEC; Gautier J; Ziegler DS; Preusser M; Wick W; Weller M, 2021, 'Development of randomized trials in adults with medulloblastoma—the example of eortc 1634-btg/noa-23', Cancers, 13, http://dx.doi.org/10.3390/cancers13143451

Perreault S; Doz F; Geoerger B; Nysom K; Øra I; Boni V; Chisholm J; DuBois SG; Gerber NU; Goto H; Grilley-Olson JE; Hansford JR; Kang HJ; Capra M; Schulte JH; Stefanowicz J; Tahara M; Ziegler DS; Norenberg R; Dima L; De La Cuesta E; Laetsch TW; van Tilburg CM, 2021, 'RARE-07. EFFICACY AND SAFETY OF LAROTRECTINIB IN PEDIATRIC PATIENTS WITH TROPOMYOSIN RECEPTOR KINASE (TRK) FUSION-POSITIVE PRIMARY CENTRAL NERVOUS SYSTEM (CNS) TUMORS', Neuro-Oncology, 23, pp. i42 - i42, http://dx.doi.org/10.1093/neuonc/noab090.168

Kilburn LB; Jabado N; Franson A; Chi SN; Fisher MJ; Hargrave DR; Hansford JR; Ziegler DS; Landi D; Kang HJ; Gerber NU; Yalon-Oren M; Cornelio I; Blackman SC; Cox MC; Witt O; Prados M; Mueller S, 2021, 'FIREFLY-1: A phase 2 study of the pan-RAF inhibitor DAY101 in pediatric patients with low-grade glioma.', Journal of Clinical Oncology, 39, pp. TPS10056 - TPS10056, http://dx.doi.org/10.1200/jco.2021.39.15_suppl.tps10056

Morgenstern DA; Mascarenhas L; Campbell M; Ziegler DS; Nysom K; Casanova M; Pappo AS; Albert CM; Xia M; Barker SS; Wright J; Laetsch TW, 2021, 'Oral selpercatinib in pediatric patients (pts) with advanced RET-altered solid or primary CNS tumors: Preliminary results from the phase 1/2 LIBRETTO-121 trial.', Journal of Clinical Oncology, 39, pp. 10009 - 10009, http://dx.doi.org/10.1200/jco.2021.39.15_suppl.10009

Chung J; Maruvka YE; Sudhaman S; Kelly J; Haradhvala NJ; Bianchi V; Edwards M; Forster VJ; Nunes NM; Galati MA; Komosa M; Deshmukh S; Cabric V; Davidson S; Zatzman M; Light N; Hayes R; Brunga L; Anderson ND; Ho B; Hodel KP; Siddaway R; Morrissy AS; Bowers DC; Larouche V; Bronsema A; Osborn M; Cole KA; Opocher E; Mason G; Thomas GA; George B; Ziegler DS; Lindhorst S; Vanan M; Yalon-Oren M; Reddy AT; Massimino M; Tomboc P; Van Damme A; Lossos A; Durno C; Aronson M; Morgenstern DA; Bouffet E; Huang A; Taylor MD; Villani A; Malkin D; Hawkins CE; Pursell ZF; Shlien A; Kunkel TA; Getz G; Tabori U, 2021, 'DNA polymerase and mismatch repair exert distinct microsatellite instability signatures in normal and malignant human cells', Cancer Discovery, 11, pp. 1176 - 1191, http://dx.doi.org/10.1158/2159-8290.CD-20-0790

Hamasaki T; Harris PG; Bureau NJ; Gaudreault N; Ziegler D; Choinière M, 2021, 'Efficacy of Surgical Interventions for Trapeziometacarpal (Thumb Base) Osteoarthritis: A Systematic Review', Journal of Hand Surgery Global Online, 3, pp. 139 - 148, http://dx.doi.org/10.1016/j.jhsg.2021.02.003

Ryan AL; Burns C; Gupta AK; Samarasekera R; Ziegler DS; Kirby ML; Alvaro F; Downie P; Laughton SJ; Cross S; Hassall T; McCowage GB; Hansford JR; Kotecha RS; Gottardo NG, 2021, 'Malignant Melanoma in Children and Adolescents Treated in Pediatric Oncology Centers: An Australian and New Zealand Children’s Oncology Group (ANZCHOG) Study', Frontiers in Oncology, 11, http://dx.doi.org/10.3389/fonc.2021.660172

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