Select Publications
Journal articles
2017, 'Endocrine therapy for breast cancer: A Renaissance', The Endocrinologist, pp. 13 - 14
,2017, 'Secreted Tumor Antigens – Immune Biomarkers for Diagnosis and Therapy', Proteomics, 17, http://dx.doi.org/10.1002/pmic.201600442
,2017, 'Sensitizing HR-proficient cancers to PARP inhibitors', Molecular and Cellular Oncology, 4, http://dx.doi.org/10.1080/23723556.2017.1299272
,2017, 'Neoadjuvant interferons: Critical for effective PD-1–based immunotherapy in TNBC', Cancer Immunology Research, 5, pp. 871 - 884, http://dx.doi.org/10.1158/2326-6066.CIR-17-0150
,2017, 'Erratum: The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy (Endocrine-related cancer (2017) 24 4 (R123-R144) PII: ERC160404e)', Endocrine-related cancer, 24, pp. X1, http://dx.doi.org/10.1530/ERC-16-0404e
,2017, 'The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy', Endocrine-Related Cancer, 24, pp. R123 - R144, http://dx.doi.org/10.1530/ERC-16-0404
,2017, 'Enhancer-Mediated Oncogenic Function of the Menin Tumor Suppressor in Breast Cancer', Cell Reports, 18, pp. 2359 - 2372, http://dx.doi.org/10.1016/j.celrep.2017.02.025
,2017, 'The role of MDM2 and MDM4 in breast cancer development and prevention', Journal of molecular cell biology, 9, pp. 53 - 61, http://dx.doi.org/10.1093/jmcb/mjx007
,2017, 'PATINA: A randomized open label phase III trial to evaluate the efficacy and safety of palbociclib + anti HER2 therapy + endocrine therapy vs anti HER2 therapy + endocrine therapy after induction treatment for hormone receptor positive, HER2-positive metastatic breast cancer', Annals of Oncology, 28, pp. v107 - v108, http://dx.doi.org/10.1093/annonc/mdx365.087
,2016, 'EMT, cell plasticity and metastasis', Cancer and Metastasis Reviews, 35, pp. 645 - 654, http://dx.doi.org/10.1007/s10555-016-9648-7
,2016, 'Pushing estrogen receptor around in breast cancer', Endocrine-Related Cancer, 23, pp. T227 - T241, http://dx.doi.org/10.1530/ERC-16-0427
,2016, 'CDK12 Inhibition Reverses De Novo and Acquired PARP Inhibitor Resistance in BRCA Wild-Type and Mutated Models of Triple-Negative Breast Cancer', Cell Reports, 17, pp. 2367 - 2381, http://dx.doi.org/10.1016/j.celrep.2016.10.077
,2016, 'Adjuvant endocrine therapy in women with oestrogen-receptor-positive breast cancer: how should the skeletal and vascular side effects be assessed and managed?', Clinical Endocrinology, 85, pp. 689 - 693, http://dx.doi.org/10.1111/cen.13172
,2016, 'Renewed interest in the progesterone receptor in breast cancer', British Journal of Cancer, 115, pp. 909 - 911, http://dx.doi.org/10.1038/bjc.2016.303
,2016, 'IMP3 promotes stem-like properties in triple-negative breast cancer by regulating SLUG', Oncogene, 35, pp. 1111 - 1121, http://dx.doi.org/10.1038/onc.2015.164
,2016, 'Clinical overview of MDM2/X-targeted therapies', Frontiers in Oncology, 6, http://dx.doi.org/10.3389/fonc.2016.00007
,2016, 'MECP2 is a frequently amplified oncogene with a novel epigenetic mechanism that mimics the role of activated RAS in malignancy', Cancer Discovery, 6, pp. 45 - 58, http://dx.doi.org/10.1158/2159-8290.CD-15-0341
,2015, 'Erratum: IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel (Nature Communications (2015) 6 (8746) DOI: 10.1038/ncomms9746)', Nature Communications, 6, http://dx.doi.org/10.1038/ncomms10054
,2015, 'IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel', Nature Communications, 6, http://dx.doi.org/10.1038/ncomms9746
,2015, 'CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer', Cell, 163, pp. 174 - 186, http://dx.doi.org/10.1016/j.cell.2015.08.063
,2015, 'Targeting the Androgen Receptor in Breast Cancer', Current Oncology Reports, 17, http://dx.doi.org/10.1007/s11912-014-0427-8
,2015, 'A laminin 511 matrix is regulated by Taz and functions as the ligand for the α6Bβ1 integrin to sustain breast cancer stem cells', Genes and Development, 29, pp. 1 - 6, http://dx.doi.org/10.1101/gad.253682.114
,2014, 'PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination–mediated DNA repair', Cancer Discovery, 4, pp. 1430 - 1447, http://dx.doi.org/10.1158/2159-8290.CD-13-0891
,2014, 'Phosphorylation of ETS1 by src family kinases prevents its recognition by the COP1 tumor suppressor', Cancer Cell, 26, pp. 222 - 234, http://dx.doi.org/10.1016/j.ccr.2014.06.026
,2014, 'Updates on the management of breast cancer brain metastases', Oncology (Williston Park), 28, pp. 572 - 578
,2014, 'MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells', eLife, 2014, http://dx.doi.org/10.7554/eLife.01763
,2014, 'Importance of breast cancer subtype in the development of androgen-receptor-directed therapy', Current Breast Cancer Reports, 6, pp. 71 - 78, http://dx.doi.org/10.1007/s12609-014-0140-5
,2014, 'XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway', Nature, 508, pp. 103 - 107, http://dx.doi.org/10.1038/nature13119
,2013, 'Protein Kinase C α Is a Central Signaling Node and Therapeutic Target for Breast Cancer Stem Cells', Cancer Cell, 24, pp. 347 - 364, http://dx.doi.org/10.1016/j.ccr.2013.08.005
,2013, 'The RasGAP Gene, RASAL2, Is a Tumor and Metastasis Suppressor', Cancer Cell, 24, pp. 365 - 378, http://dx.doi.org/10.1016/j.ccr.2013.08.004
,2013, 'Breast cancer in adolescents and young adults: A review with a focus on biology', JNCCN Journal of the National Comprehensive Cancer Network, 11, pp. 1060 - 1069, http://dx.doi.org/10.6004/jnccn.2013.0128
,2013, 'PDEF Promotes Luminal Differentiation and Acts as a Survival Factor for ER-Positive Breast Cancer Cells', Cancer Cell, 23, pp. 753 - 767, http://dx.doi.org/10.1016/j.ccr.2013.04.026
,2013, 'Amplitude modulation of androgen signaling by c-MYC', Genes and Development, 27, pp. 734 - 748, http://dx.doi.org/10.1101/gad.209569.112
,2012, 'IκB kinase ε phosphorylates TRAF2 to promote mammary epithelial cell transformation', Molecular and Cellular Biology, 32, pp. 4756 - 4768, http://dx.doi.org/10.1128/MCB.00468-12
,2012, 'Elucidating the role of androgen receptors and breast cancer.', Clinical Investigation, 2, pp. 1003 - 1011
,2012, 'Natural history of hormone receptor positive breast cancer', Oncology (Williston Park), 26, pp. 688 - 694
,2012, 'New insights and emerging therapies in breast cancer brain metastases', Oncology (Williston Park), 26, pp. 652 - 659
,2012, 'Estrogen receptor (ER) signaling in normal, BRCA (B) 1 and B2 mutation associated, and ER-positive breast cancer (BC) mammary cells.', Journal of Clinical Oncology, 30, pp. 576 - 576, http://dx.doi.org/10.1200/jco.2012.30.15_suppl.576
,2012, 'Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737', Proceedings of the National Academy of Sciences of the United States of America, 109, pp. 2766 - 2771, http://dx.doi.org/10.1073/pnas.1104778108
,2012, 'Targeting BCL-2–expressing basal-like breast cancer with BH3-mimetics', Hereditary cancer in clinical practice, 10, pp. A25 - A25, http://dx.doi.org/10.1186/1897-4287-10-s2-a25
,2011, 'Abstract 941: Targeting androgen receptor in estrogen receptor-negative breast cancer', Cancer Research, 71, pp. 941 - 941, http://dx.doi.org/10.1158/1538-7445.am2011-941
,2011, 'Targeting Androgen Receptor in Estrogen Receptor-Negative Breast Cancer', Cancer Cell, 20, pp. 119 - 131, http://dx.doi.org/10.1016/j.ccr.2011.05.026
,2011, 'S17 Breast stem and progenitor cells in cancer – Therapeutic implications', The Breast, 20, pp. S6 - S6, http://dx.doi.org/10.1016/s0960-9776(11)70020-0
,2011, 'Will preoperative trials change future clinical practice?', Clinical Investigation, 1, pp. 59 - 73, http://dx.doi.org/10.4155/cli.10.3
,2010, 'ROAST: Rotation gene set tests for complex microarray experiments', Bioinformatics, 26, pp. 2176 - 2182, http://dx.doi.org/10.1093/bioinformatics/btq401
,2010, 'Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways', Breast Cancer Research, 12, http://dx.doi.org/10.1186/bcr2560
,2009, 'Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers', Nature Medicine, 15, pp. 907 - 913, http://dx.doi.org/10.1038/nm.2000
,2009, 'Investigation of human mammary stem and progenitor subpopulations from BRCA1 mutation carriers and noncarriers', Journal of Clinical Oncology, 27, pp. 504 - 504, http://dx.doi.org/10.1200/jco.2009.27.15_suppl.504
,2007, 'Optimizing the approach to patients with potentially resectable liver metastases from colorectal cancer', ANZ Journal of Surgery, 77, pp. 941 - 947, http://dx.doi.org/10.1111/j.1445-2197.2007.04287.x
,2007, 'Diagnosing cancer: changing patterns of care', INTERNAL MEDICINE JOURNAL, 37, pp. 124 - 126, http://dx.doi.org/10.1111/j.1445-5994.2007.01246.x
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