By Professor Georgina Hold

Journal articles

Rokkas T; Hold GL, 2023, 'A systematic review, pairwise meta-analysis and network meta-analysis of randomized controlled trials exploring the role of fecal microbiota transplantation in irritable bowel syndrome', European Journal of Gastroenterology and Hepatology, 35, pp. 471 - 479, http://dx.doi.org/10.1097/MEG.0000000000002519

Mah C; Jayawardana T; Leong G; Koentgen S; Lemberg D; Connor SJ; Rokkas T; Grimm MC; Leach ST; Hold GL, 2023, 'Assessing the Relationship between the Gut Microbiota and Inflammatory Bowel Disease Therapeutics: A Systematic Review', Pathogens, 12, http://dx.doi.org/10.3390/pathogens12020262

Zhang F; Gia A; Chen G; Gong L; Behary J; Hold GL; Zekry A; Tang X; Sun Y; El-Omar E; Jiang XT, 2023, 'Critical Assessment of Whole Genome and Viral Enrichment Shotgun Metagenome on the Characterization of Stool Total Virome in Hepatocellular Carcinoma Patients', Viruses, 15, pp. 53, http://dx.doi.org/10.3390/v15010053

Oosterlinck B; Arras W; De Man J; Geboes K; De Schepper HU; Peeters M; Lebeer S; Skieceviciene J; Hold GL; Kupcinskas J; Link A; De Winter BY; Smet A, 2023, 'Sa1865 MUCIN-MICROBIOME SIGNATURES SHAPE THE TUMOUR MICROENVIRONMENT IN GASTRIC CANCER', Gastroenterology, 164, pp. S - 468, http://dx.doi.org/10.1016/s0016-5085(23)02079-6

O'Donnell M; Teasdale S; Chua X-Y; Hardman J; Wu N; Curtis J; Samaras K; Bolton P; Morris M; Shannon-Weickert C; Purves-Tyson T; El-Assaad F; Jiang X; Hold G; El-Omar E, 2022, 'The role of the microbiome in the metabolic health of people with schizophrenia and related psychoses: cross-sectional and pre-post lifestyle intervention analyses', Pathogens, 11, pp. 1279, http://dx.doi.org/10.3390/pathogens11111279

Little RD; Ward MG; Wright E; Jois AJ; Boussioutas A; Hold GL; Gibson PR; Sparrow MP, 2022, 'Therapeutic Drug Monitoring of Subcutaneous Infliximab in Inflammatory Bowel Disease—Understanding Pharmacokinetics and Exposure Response Relationships in a New Era of Subcutaneous Biologics', Journal of Clinical Medicine, 11, http://dx.doi.org/10.3390/jcm11206173

Carserides C; Smith K; Zinicola M; Kumar A; Swedrowska M; Scala C; Cameron G; Riches Z; Iannelli F; Pozzi G; Hold GL; Forbes B; Kelly C; Hijazi K, 2022, 'Comprehensive Study of Antiretroviral Drug Permeability at the Cervicovaginal Mucosa via an In Vitro Model', Pharmaceutics, 14, http://dx.doi.org/10.3390/pharmaceutics14091938

Gulliver EL; Young RB; Chonwerawong M; D'Adamo GL; Thomason T; Widdop JT; Rutten EL; Rossetto Marcelino V; Bryant RV; Costello SP; O'Brien CL; Hold GL; Giles EM; Forster SC, 2022, 'Review article: the future of microbiome-based therapeutics', Alimentary Pharmacology and Therapeutics, 56, pp. 192 - 208, http://dx.doi.org/10.1111/apt.17049

Breugelmans T; Oosterlinck B; Arras W; Ceuleers H; De Man J; Hold GL; De Winter BY; Smet A, 2022, 'The role of mucins in gastrointestinal barrier function during health and disease', Lancet Gastroenterology and Hepatology, 7, pp. 455 - 471, http://dx.doi.org/10.1016/S2468-1253(21)00431-3

James KR; Elmentaite R; Teichmann SA; Hold GL, 2022, 'Redefining intestinal immunity with single-cell transcriptomics', Mucosal Immunology, 15, pp. 531 - 541, http://dx.doi.org/10.1038/s41385-021-00470-y

James KR; Elmentaite R; Teichmann SA; Hold GL, 2022, 'Correction to: Redefining intestinal immunity with single-cell transcriptomics (Mucosal Immunology, (2021), 10.1038/s41385-021-00470-y)', Mucosal Immunology, 15, pp. 526 - 526, http://dx.doi.org/10.1038/s41385-022-00483-1

Amorim N; McGovern E; Raposo A; Khatiwada S; Shen S; Koentgen S; Hold G; Behary J; El-Omar E; Zekry A, 2022, 'Refining a Protocol for Faecal Microbiota Engraftment in Animal Models After Successful Antibiotic-Induced Gut Decontamination', Frontiers in Medicine, 9, http://dx.doi.org/10.3389/fmed.2022.770017

Shaw S; Berry S; Thomson J; Murray GI; El-Omar E; Hold GL, 2022, 'Gut Mucosal Microbiome Signatures of Colorectal Cancer Differ According to BMI Status', Frontiers in Medicine, 8, http://dx.doi.org/10.3389/fmed.2021.800566

Smet A; Kupcinskas J; Link A; Hold GL; Bornschein J, 2022, 'The Role of Microbiota in Gastrointestinal Cancer and Cancer Treatment: Chance or Curse?', Cellular and Molecular Gastroenterology and Hepatology, 13, pp. 857 - 874, http://dx.doi.org/10.1016/j.jcmgh.2021.08.013

Wu N; Mah C; Koentgen S; Zhang L; Grimm MC; El-Omar E; Hold GL, 2021, 'Inflammatory bowel disease and the gut microbiota', Proceedings of the Nutrition Society, 80, pp. 424 - 434, http://dx.doi.org/10.1017/S002966512100197X

Hansen R; Bajaj-Elliott M; Hold GL; Gerasimidis K; Iqbal TH; Amos G; Thomas LV; Marchesi JR, 2021, 'Next-generation sequencing as a clinical laboratory tool for describing different microbiotas: An urgent need for future paediatric practice', Archives of Disease in Childhood, 106, pp. 1035, http://dx.doi.org/10.1136/archdischild-2021-321683

Lambert K; Pappas D; Miglioretto C; Javadpour A; Reveley H; Frank L; Grimm MC; Samocha-Bonet D; Hold GL, 2021, 'Systematic review with meta-analysis: dietary intake in adults with inflammatory bowel disease', Alimentary Pharmacology and Therapeutics, 54, pp. 742 - 754, http://dx.doi.org/10.1111/apt.16549

Nelson A; Stewart CJ; Kennedy NA; Lodge JK; Tremelling M; Probert CS; Parkes M; Mansfield JC; Smith DL; Hold GL; Lees CW; Bridge SH; Lamb CA, 2021, 'The Impact of NOD2 Genetic Variants on the Gut Mycobiota in Crohn's Disease Patients in Remission and in Individuals without Gastrointestinal Inflammation', Journal of Crohn S and Colitis, 15, pp. 800 - 812, http://dx.doi.org/10.1093/ecco-jcc/jjaa220

Bornschein J; Tran-Nguyen T; Fernandez-Esparrach G; Ash S; Balaguer F; Bird-Lieberman EL; Córdova H; Dzerve Z; Fassan M; Leja M; Lyutakov I; Middelburg T; Moreira L; Nakov R; Nieuwenburg SAV; O'Connor A; Realdon S; De Schepper H; Smet A; Spaander MCW; Tolmanis I; Urbonas T; Weigt J; Hold GL; Link A; Kupcinskas J, 2021, 'Biopsy Sampling in Upper Gastrointestinal Endoscopy: A Survey from 10 Tertiary Referral Centres across Europe', Digestive Diseases, 39, pp. 179 - 189, http://dx.doi.org/10.1159/000511867

Mahalhal A; Burkitt MD; Duckworth CA; Hold GL; Campbell BJ; Pritchard DM; Probert CS, 2021, 'Long‐term iron deficiency and dietary iron excess exacerbate acute dextran sodium sulphate‐induced colitis and are associated with significant dysbiosis', International Journal of Molecular Sciences, 22, http://dx.doi.org/10.3390/ijms22073646

Keller JJ; Ooijevaar RE; Hvas CL; Terveer EM; Lieberknecht SC; Högenauer C; Arkkila P; Sokol H; Gridnyev O; Mégraud F; Kump PK; Nakov R; Goldenberg SD; Satokari R; Tkatch S; Sanguinetti M; Cammarota G; Dorofeev A; Gubska O; Ianiro G; Mattila E; Arasaradnam RP; Sarin SK; Sood A; Putignani L; Alric L; Baunwall SMD; Kupcinskas J; Link A; Goorhuis AG; Verspaget HW; Ponsioen C; Hold GL; Tilg H; Kassam Z; Kuijper EJ; Gasbarrini A; Mulder CJJ; Williams HRT; Vehreschild MJGT, 2021, 'A standardised model for stool banking for faecal microbiota transplantation: a consensus report from a multidisciplinary UEG working group', United European Gastroenterology Journal, 9, pp. 229 - 247, http://dx.doi.org/10.1177/2050640620967898

Williams AJ; Paramsothy R; Wu N; Ghaly S; Leach S; Paramsothy S; Corte C; O'Brien C; Burke C; Wark G; Samocha-Bonet D; Lambert K; Ahlenstiel G; Wasinger V; Dutt S; Pavli P; Grimm M; Lemberg D; Connor S; Leong R; Hold G, 2021, 'Australia IBD Microbiome (AIM) Study: Protocol for a multicentre longitudinal prospective cohort study', BMJ Open, 11, http://dx.doi.org/10.1136/bmjopen-2020-042493

Susic D; Davis G; O'Sullivan AJ; McGovern E; Harris K; Roberts LM; Craig ME; Mangos G; Hold GL; El-Omar EM; Henry A, 2020, 'Microbiome Understanding in Maternity Study (MUMS), an Australian prospective longitudinal cohort study of maternal and infant microbiota: study protocol', BMJ Open, 10, pp. e040189, http://dx.doi.org/10.1136/bmjopen-2020-040189

Link A; Hold G, 2020, 'First Case of Covid-19 in the United States', New England Journal of Medicine, 382, pp. e53, http://dx.doi.org/10.1056/NEJMc2004794

Bezawada N; Phang TH; Hold GL; Hansen R, 2020, 'Autism Spectrum Disorder and the Gut Microbiota in Children: A Systematic Review', Annals of Nutrition and Metabolism, 76, pp. 16 - 29, http://dx.doi.org/10.1159/000505363

Rajilic-Stojanovic M; Figueiredo C; Smet A; Hansen R; Kupcinskas J; Rokkas T; Andersen L; Machado JC; Ianiro G; Gasbarrini A; Leja M; Gisbert JP; Hold GL, 2020, 'Systematic review: gastric microbiota in health and disease', Alimentary Pharmacology and Therapeutics, 51, pp. 582 - 602, http://dx.doi.org/10.1111/apt.15650

Ormsby MJ; Johnson SA; Carpena N; Meikle LM; Goldstone RJ; McIntosh A; Wessel HM; Hulme HE; McConnachie CC; Connolly JPR; Roe AJ; Hasson C; Boyd J; Fitzgerald E; Gerasimidis K; Morrison D; Hold GL; Hansen R; Walker D; Smith DGE; Wall DM, 2020, 'Propionic Acid Promotes the Virulent Phenotype of Crohn's Disease-Associated Adherent-Invasive Escherichia coli', Cell Reports, 30, pp. 2297 - 2305.e5, http://dx.doi.org/10.1016/j.celrep.2020.01.078

Gemmell M; Berry S; Mukhopadhya I; Gong L; Hansen R; Hold G, 2019, 'Draft genome sequences of a Campylobacter curvus and three Campylobacter ureolyticus strains isolated from human colonic mucosal tissue', Microbiota in Health and Disease, 1, pp. e148 - e148, http://dx.doi.org/10.26355/mhd_201911_148

Rokkas T; Gisbert JP; Gasbarrini A; Hold GL; Tilg H; Malfertheiner P; Megraud F; O'Morain C, 2019, 'A network meta-analysis of randomized controlled trials exploring the role of fecal microbiota transplantation in recurrent Clostridium difficile infection', United European Gastroenterology Journal, 7, pp. 1051 - 1063, http://dx.doi.org/10.1177/2050640619854587

Hold GL; Allen-Vercoe E, 2019, 'Gut microbial biofilm composition and organisation holds the key to CRC', Nature Reviews Gastroenterology and Hepatology, 16, pp. 329 - 330, http://dx.doi.org/10.1038/s41575-019-0148-4

Ormsby MJ; Logan M; Johnson SA; McIntosh A; Fallata G; Papadopoulou R; Papachristou E; Hold GL; Hansen R; Ijaz UZ; Russell RK; Gerasimidis K; Wall DM, 2019, 'Inflammation associated ethanolamine facilitates infection by Crohn's disease-linked adherent-invasive Escherichia coli', Ebiomedicine, 43, pp. 325 - 332, http://dx.doi.org/10.1016/j.ebiom.2019.03.071

Mukhopadhya I; Segal JP; Carding SR; Hart AL; Hold GL, 2019, 'The gut virome: the ‘missing link’ between gut bacteria and host immunity?', Therapeutic Advances in Gastroenterology, 12, http://dx.doi.org/10.1177/1756284819836620

Hsu T; Gemmell MR; Franzosa EA; Berry S; Mukhopadhya I; Hansen R; Michaud M; Nielsen H; Miller WG; Nielsen H; Bajaj-Elliott M; Huttenhower C; Garrett WS; Hold GL, 2019, 'Comparative genomics and genome biology of Campylobacter showae', Emerging Microbes and Infections, 8, pp. 827 - 840, http://dx.doi.org/10.1080/22221751.2019.1622455

Hold GL; Hansen R, 2019, 'Impact of the gastrointestinal microbiome in health and disease: Co-evolution with the host immune system', , 421, pp. 303 - 318, http://dx.doi.org/10.1007/978-3-030-15138-6_12

Bond A; Greenwood R; Lewis S; Corfe B; Sarkar S; O’Toole P; Rooney P; Burkitt M; Hold G; Probert C, 2019, 'Volatile organic compounds emitted from faeces as a biomarker for colorectal cancer', Alimentary Pharmacology and Therapeutics, 49, pp. 1005 - 1012, http://dx.doi.org/10.1111/apt.15140

Keller JJ; Vehreschild MJ; Hvas CL; Jørgensen SM; Kupciskas J; Link A; Mulder CJ; Goldenberg SD; Arasaradnam R; Sokol H; Gasbarrini A; Hoegenauer C; Terveer EM; Kuijper EJ; Arkkila P; FMT UWGOTSAGISBF, 2019, 'Stool for fecal microbiota transplantation should be classified as a transplant product and not as a drug', United European Gastroenterology Journal, 7, pp. 1408 - 1410, http://dx.doi.org/10.1177/2050640619887579

Hansen R; Gibson S; De Paiva Alves E; Goddard M; MacLaren A; Karcher AM; Berry S; Collie-Duguid ESR; El-Omar E; Munro M; Hold GL, 2018, 'Adaptive response of neonatal sepsis-derived Group B Streptococcus to bilirubin', Scientific Reports, 8, pp. 6470, http://dx.doi.org/10.1038/s41598-018-24811-3

Gemmell MR; Berry S; Mukhopadhya I; Hansen R; Nielsen HL; Bajaj-Elliott M; Nielsen H; Hold GL, 2018, 'Comparative genomics of Campylobacter concisus: Analysis of clinical strains reveals genome diversity and pathogenic potential', Emerging Microbes and Infections, 7, http://dx.doi.org/10.1038/s41426-018-0118-x

Ianiro G; Maida M; Burisch J; Simonelli C; Hold G; Ventimiglia M; Gasbarrini A; Cammarota G, 2018, 'Efficacy of different faecal microbiota transplantation protocols for Clostridium difficile infection: A systematic review and meta-analysis', United European Gastroenterology Journal, 6, pp. 1232 - 1244, http://dx.doi.org/10.1177/2050640618780762

McIlroy JR; Nalagatla N; Hansen R; Hart A; Hold GL, 2018, 'Faecal microbiota transplantation as a treatment for inflammatory bowel disease: A national survey of adult and paediatric gastroenterologists in the UK', Frontline Gastroenterology, 9, pp. 250 - 255, http://dx.doi.org/10.1136/flgastro-2017-100936

Mahalhal A; Williams JM; Johnson S; Ellaby N; Duckworth CA; Burkitt MD; Liu X; Hold GL; Campbell BJ; Mark Pritchard D; Probert CS, 2018, 'Oral iron exacerbates colitis and influences the intestinal microbiome', Plos One, 13, http://dx.doi.org/10.1371/journal.pone.0202460

Kupcinskas J; Hold GL, 2018, 'Other Helicobacters and the gastric microbiome', Helicobacter, 23, http://dx.doi.org/10.1111/hel.12521

Garg M; Hendy P; Ding JN; Shaw S; Hold G; Hart A, 2018, 'The effect of Vitamin D on intestinal inflammation and faecal microbiota in patients with ulcerative colitis', Journal of Crohn S and Colitis, 12, pp. 963 - 972, http://dx.doi.org/10.1093/ecco-jcc/jjy052

Kennedy NA; Lamb CA; Berry SH; Walker AW; Mansfield J; Parkes M; Simpkins R; Tremelling M; Nutland S; Parkhill J; Probert C; Hold GL; Lees CW, 2018, 'The impact of NOD2 variants on fecal microbiota in Crohn's disease and controls without gastrointestinal disease', Inflammatory Bowel Diseases, 24, pp. 583 - 592, http://dx.doi.org/10.1093/ibd/izx061

Segal JP; Oke S; Hold GL; Clark SK; Faiz OD; Hart AL, 2018, 'Systematic review: ileoanal pouch microbiota in health and disease', Alimentary Pharmacology and Therapeutics, 47, pp. 466 - 477, http://dx.doi.org/10.1111/apt.14454

McIlroy J; Nalagatla N; Hansen R; Hart A; Hold G, 2018, 'P659 FMT as a treatment for IBD: A national survey of gastroenterologists in the UK', Journal of Crohn's and Colitis, 12, pp. s443 - s444, http://dx.doi.org/10.1093/ecco-jcc/jjx180.786

Douglas GM; Hansen R; Jones CMA; Dunn KA; Comeau AM; Bielawski JP; Tayler R; El-Omar EM; Russell RK; Hold GL; Langille MGI; Limbergen JV, 2018, 'Multi-omics differentially classify disease state and treatment outcome in pediatric Crohn's disease', Microbiome, 6, http://dx.doi.org/10.1186/s40168-018-0398-3

Brunner K; John CM; Phillips NJ; Alber DG; Gemmell MR; Hansen R; Nielsen HL; Hold GL; Bajaj-Elliott M; Jarvis GA, 2018, 'Novel Campylobacter concisus lipooligosaccharide is a determinant of inflammatory potential and virulence', Journal of Lipid Research, 59, pp. 1893 - 1905, http://dx.doi.org/10.1194/jlr.M085860

McIlroy J; Ianiro G; Mukhopadhya I; Hansen R; Hold GL, 2018, 'Review article: the gut microbiome in inflammatory bowel disease—avenues for microbial management', Alimentary Pharmacology and Therapeutics, 47, pp. 26 - 42, http://dx.doi.org/10.1111/apt.14384

Lawler M; Alsina D; Adams RA; Anderson AS; Brown G; Fearnhead NS; Fenwick SW; Halloran SP; Hochhauser D; Hull MA; Koelzer VH; McNair AGK; Monahan KJ; Näthke I; Norton C; Novelli MR; Steele RJC; Thomas AL; Wilde LM; Wilson RH; Tomlinson I; Initiative OBOTBCUCRGICC; Ahmedzai SH; Andreyev J; Arbuthnot N; Atkin W; Bach S; Berkman L; Bloor N; Boulter V; Brewster D; Brown K; Burn J; Cazier J-B; Chau I; Cheadle J; Cole A; Coyle V; Cunningham D; Davies M; Downward J; Dunlop M; Fraser C; Gerlinger M; Glaser A; Goh V; De castro DG; Graham T; Griffith J; Halligan S; Hamilton W; Hepburn J; Haynes R; Higgins J; Hold G; Holden G; Houlston R; Hubbard G; Iqba T; Irvine AE; Iveson T; Jakowiw N; Jackson I; Jefford M; Longley D; Mcdermott U; Machesney M; Maher J; Marchesi J; Maughan T; Middleton G; Moss B; Moss M; Murchie P; O’sullivan P; Robertson C; Rutter M; Samuel L; Sansom O; Saxton J; Seward E; Sharma R; Smith T; Sottoriva A; Steward W; Stocker P; Sweetman G; Von Wagner C; Williams A; Winton D, 2018, 'Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer', Gut, 67, pp. 179, http://dx.doi.org/10.1136/gutjnl-2017-315333

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