By Professor Georgina Hold

Journal articles

Boyle SE; Cotton SC; Myint PK; Hold GL, 2017, 'The influence of early research experience in medical school on the decision to intercalate and future career in clinical academia: A questionnaire study', BMC Medical Education, 17, pp. 245, http://dx.doi.org/10.1186/s12909-017-1066-1

Maida M; Macaluso FS; Ianiro G; Mangiola F; Sinagra E; Hold G; Maida C; Cammarota G; Gasbarrini A; Scarpulla G, 2017, 'Screening of colorectal cancer: present and future', Expert Review of Anticancer Therapy, 17, pp. 1131 - 1146, http://dx.doi.org/10.1080/14737140.2017.1392243

Berry SH; El-Omar EM; Hold GL; Mukhopadhya A, 2017, 'THE EFFECT OF LACTULOSE ON THE FAECAL MICROBIOTA OF PATIENTS WITH MINIMAL HEPATIC ENCEPHALOPATHY', GASTROENTEROLOGY, 152, pp. S1049 - S1049, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000403140304299&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Mukhopadhya I; Murdoch H; Berry S; Hunt A; Iturriza-Gomara M; Smith-Palmer A; Cameron JC; Hold GL, 2017, 'Changing molecular epidemiology of rotavirus infection after introduction of monovalent rotavirus vaccination in Scotland', Vaccine, 35, pp. 156 - 163, http://dx.doi.org/10.1016/j.vaccine.2016.11.028

Watt E; Gemmell MR; Berry S; Glaire M; Farquharson F; Louis P; Murray GI; El-Omar E; Hold GL, 2016, 'Extending colonic mucosal microbiome analysis-assessment of colonic lavage as a proxy for endoscopic colonic biopsies', Microbiome, 4, pp. 61, http://dx.doi.org/10.1186/s40168-016-0207-9

Mukhopadhya I; Murray GI; Duncan L; Yuecel R; Shattock R; Kelly C; Iannelli F; Pozzi G; El-Omar EM; Hold GL; Hijazi K, 2016, 'Transporters for antiretroviral drugs in colorectal CD4+ T cells and circulating α4β7 integrin CD4+ T cells: Implications for HIV microbicides', Molecular Pharmaceutics, 13, pp. 3334 - 3340, http://dx.doi.org/10.1021/acs.molpharmaceut.6b00351

Hold GL, 2016, 'Gastrointestinal Microbiota and Colon Cancer', Digestive Diseases, 34, pp. 244 - 250, http://dx.doi.org/10.1159/000443358

Mukhopadhya I; Murray GI; Berry S; Thomson J; Frank B; Gwozdz G; Ekeruche-Makinde J; Shattock R; Kelly C; Iannelli F; Pozzi G; El-Omar EM; Hold GL; Hijazi K, 2016, 'Drug transporter gene expression in human colorectal tissue and cell lines: Modulation with antiretrovirals for microbicide optimization', Journal of Antimicrobial Chemotherapy, 71, pp. 372 - 386, http://dx.doi.org/10.1093/jac/dkv335

Marchesi JR; Adams DH; Fava F; Hermes GDA; Hirschfield GM; Hold G; Quraishi MN; Kinross J; Smidt H; Tuohy KM; Thomas LV; Zoetendal EG; Hart A, 2016, 'The gut microbiota and host health: A new clinical frontier', Gut, 65, pp. 330 - 339, http://dx.doi.org/10.1136/gutjnl-2015-309990

Porter R; Murray GI; Petty R; El-Omar EM; Hold G; McLean MH, 2016, 'HMGB1 AS A PROGNOSTIC BIOMARKER IN THE PROGRESSION OF BARRETT'S OESOPHAGUS', GUT, 65, pp. A133 - A133, http://dx.doi.org/10.1136/gutjnl-2016-312388.239

Hansen R; Scott KP; Khan S; Martin JC; Berry SH; Stevenson M; Okpapi A; Munro MJ; Hold GL, 2015, 'First-Pass Meconium Samples from Healthy Term Vaginally-Delivered Neonates: An Analysis of the Microbiota', Plos One, 10, http://dx.doi.org/10.1371/journal.pone.0133320

Hijazi K; Cuppone AM; Smith K; Stincarelli MA; Ekeruche-Makinde J; De Falco G; Hold GL; Shattock R; Kelly CG; Pozzi G; Iannelli F, 2015, 'Expression of genes for drug transporters in the human female genital tract and modulatory effect of antiretroviral drugs', Plos One, 10, http://dx.doi.org/10.1371/journal.pone.0131405

Basavaraju U; Shebl FM; Palmer AJ; Berry S; Hold GL; El-Omar EM; Rabkin CS, 2015, 'Cytokine gene polymorphisms, cytokine levels and the risk of colorectal neoplasia in a screened population of Northeast Scotland', European Journal of Cancer Prevention, 24, pp. 296 - 304, http://dx.doi.org/10.1097/CEJ.0000000000000087

Mukhopadhya I; Hansen R; Meharg C; Thomson JM; Russell RK; Berry SH; El-Omar EM; Hold GL, 2015, 'The fungal microbiota of de-novo paediatric inflammatory bowel disease', Microbes and Infection, 17, pp. 304 - 310, http://dx.doi.org/10.1016/j.micinf.2014.12.001

Hijazi K; Lowe T; Meharg C; Berry SH; Foley J; Hold GL, 2015, 'Mucosal microbiome in patients with recurrent aphthous stomatitis', Journal of Dental Research, 94, pp. 87 - 94, http://dx.doi.org/10.1177/0022034514565458

Hold GL; Garrett WS, 2015, 'Gut microbiota: Microbiota organization-a key to understanding CRC development', Nature Reviews Gastroenterology and Hepatology, 12, pp. 128 - 129, http://dx.doi.org/10.1038/nrgastro.2015.25

Connors J; Hansen R; Dunn KA; Langille MG; Russell RK; Otley AR; MacIntyre B; El-Omar E; Bielawski JP; Hold GL; Van Limbergen J, 2015, '169 Assessment of Community Structure and Predictive Functional Profiling of the Mucosa-Associated Microbiome Implicates Alterations in Benzoate Metabolism in ‘de novo’ IBD After Pouch-Surgery and in Treatment-Naïve Pediatric IBD', Gastroenterology, 148, pp. S - 45, http://dx.doi.org/10.1016/s0016-5085(15)30158-x

Liu JZ; van Sommeren S; Huang H; Ng SC; Alberts R; Takahashi A; Ripke S; Lee JC; Jostins L; Shah T; Abedian S; Cheon JH; Cho J; Daryani NE; Franke L; Fuyuno Y; Hart A; Juyal RC; Juyal G; Kim WH; Morris AP; Poustchi H; Newman WG; Midha V; Orchard TR; Vahedi H; Sood A; Sung JJY; Malekzadeh R; Westra H-J; Yamazaki K; Yang S-K; Barrett JC; Franke A; Alizadeh BZ; Parkes M; B K T; Daly MJ; Kubo M; Anderson CA; Weersma RK, 2015, 'Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations', Nature Genetics, 47, pp. 979 - 986, http://dx.doi.org/10.1038/ng.3359

Khan S; Hansen R; Scott K; Martin J; Berry S; Stevenson M; Okapapi A; Hold G; Munro M, 2015, 'G116(P) The human gut is probably sterile at birth', Archives of Disease in Childhood, 100, pp. a50 - a51, http://dx.doi.org/10.1136/archdischild-2015-308599.115

Kennedy NA; Walker AW; Berry SH; Lamb CA; Lewis S; Mansfield JC; Parkes M; Parkhill J; Probert C; Read D; Satsangi J; Simpkins RL; Tomlinson D; Tremelling M; Nutland SL; Hold GL; Lees CW, 2015, 'Mo1816 The Impact of NOD2 Variants on Gut Microbiota in Crohn's Disease and Healthy Controls', Gastroenterology, 148, pp. S - 718, http://dx.doi.org/10.1016/s0016-5085(15)32446-x

Hold GL, 2014, 'The gut microbiota, dietary extremes and exercise', Gut, 63, pp. 1838 - 1839, http://dx.doi.org/10.1136/gutjnl-2014-307305

Hold GL; Berry S; Saunders KA; Drew J; Mayer C; Brookes H; Gay NJ; El-Omar EM; Bryant CE, 2014, 'The TLR4 D299G and T399I SNPs are constitutively active to up-regulate expression of Trif-dependent genes', Plos One, 9, pp. e111460, http://dx.doi.org/10.1371/journal.pone.0111460

Mactier KE; Glaire MA; Basavaraju U; El-Omar EM; Hold GL, 2014, 'MicroRNAs in gastrointestinal malignancy: A tool in cancer prevention?', European Journal of Cancer Prevention, 23, pp. 540 - 549, http://dx.doi.org/10.1097/CEJ.0000000000000014

Louis P; Hold GL; Flint HJ, 2014, 'The gut microbiota, bacterial metabolites and colorectal cancer', Nature Reviews Microbiology, 12, pp. 661 - 672, http://dx.doi.org/10.1038/nrmicro3344

Adams AT; Kennedy NA; Hansen R; Ventham NT; O'Leary KR; Drummond HE; Noble CL; El-Omar E; Russell RK; Wilson DC; Nimmo ER; Hold GL; Satsangi J, 2014, 'Two-stage genome-wide methylation profiling in childhood-onset Crohn's disease implicates epigenetic alterations at the VMP1/MIR21 and HLA loci', Inflammatory Bowel Diseases, 20, pp. 1784 - 1793, http://dx.doi.org/10.1097/MIB.0000000000000179

Kennedy NA; Walker AW; Berry SH; Duncan SH; Farquarson FM; Louis P; Thomson JM; Satsangi J; Flint HJ; Parkhill J; Lees CW; Hold GL, 2014, 'The impact of different DNA extraction kits and laboratories upon the assessment of human gut microbiota composition by 16S rRNA gene sequencing', Plos One, 9, http://dx.doi.org/10.1371/journal.pone.0088982

Hold GL; Smith M; Grange C; Watt ER; El-Omar EM; Mukhopadhya I, 2014, 'Role of the gut microbiota in inflammatory bowel disease pathogenesis: What have we learnt in the past 10 years?', World Journal of Gastroenterology, 20, pp. 1192 - 1210, http://dx.doi.org/10.3748/wjg.v20.i5.1192

Folmer F; Basavaraju U; Jaspars M; Hold G; El-Omar E; Dicato M; Diederich M, 2014, 'Anticancer effects of bioactive berry compounds', Phytochemistry Reviews, 13, pp. 295 - 322, http://dx.doi.org/10.1007/s11101-013-9319-z

Hold GL; Mukhopadhya I; Hansen R, 2014, 'Diet, the microbiome, and IBD', Inflammatory Bowel Disease Monitor, 14, pp. 39 - 43

Hold GL, 2014, 'Western lifestyle: A 'master' manipulator of the intestinal microbiota?', Gut, 63, pp. 5 - 6, http://dx.doi.org/10.1136/gutjnl-2013-304969

Lochhead PJ; Mayer C-D; Hold GL; El-Omar E, 2014, '946 Genome-Wide Analysis of DNA Methylation in Low-Grade Colorectal Adenomas and Normal Colonic Mucosa', Gastroenterology, 146, pp. S - 165, http://dx.doi.org/10.1016/s0016-5085(14)60588-6

Kennedy NA; Adams AT; Hansen R; Ventham NT; O'Leary KR; Drummond H; Noble CL; El-Omar E; Russell RK; Wilson DC; Nimmo ER; Hold GL; Satsangi J, 2014, 'DOP010 Epigenome-wide analysis in childhood-onset Crohn's disease implicates MIR21 in pathogenesis and identifies multiple methylation-based diagnostic biomarkers', Journal of Crohn's and Colitis, 8, pp. s19 - s19, http://dx.doi.org/10.1016/s1873-9946(14)60035-0

Kostic AD; Chun E; Robertson L; Glickman JN; Gallini CA; Michaud M; Clancy TE; Chung DC; Lochhead P; Hold GL; El-Omar EM; Brenner D; Fuchs CS; Meyerson M; Garrett WS, 2013, 'Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment', Cell Host and Microbe, 14, pp. 207 - 215, http://dx.doi.org/10.1016/j.chom.2013.07.007

McLean MH; Thomson AJ; Murray GI; Fyfe N; Hold GL; El-Omar EM, 2013, 'Expression of neutrophil gelatinase-associated lipocalin in colorectal neoplastic progression: A marker of malignant potential?', British Journal of Cancer, 108, pp. 2537 - 2541, http://dx.doi.org/10.1038/bjc.2013.264

Hansen R; Berry SH; Mukhopadhya I; Thomson JM; Saunders KA; Nicholl CE; Bisset WM; Loganathan S; Mahdi G; Kastner-Cole D; Barclay AR; Bishop J; Flynn DM; McGrogan P; Russell RK; El-Omar EM; Hold GL, 2013, 'The Microaerophilic Microbiota of De-Novo Paediatric Inflammatory Bowel Disease: The BISCUIT Study', Plos One, 8, pp. e58825, http://dx.doi.org/10.1371/journal.pone.0058825

Kennedy NA; Walker AW; Berry SH; Duncan SH; Farquarson F; Louis P; Satsangi J; Flint HJ; Lees CW; Hold GL, 2013, 'P705 Evaluation of the impact of different commercially available DNA extraction kits and laboratories for assessing bacterial community structure in fecal samples – implications for IBD research', Journal of Crohn's and Colitis, 7, pp. S294 - S294, http://dx.doi.org/10.1016/s1873-9946(13)60726-6

Kennedy N; Walker A; Berry S; Duncan S; Farquharson F; Louis P; Satsangi J; Flint H; Lees C; Hold G, 2013, 'PTU-072 Evaluation of the Impact of different Commercially available DNA Extraction Kits and Laboratories for Assessing Bacterial Community Structure in Faecal Samples – Implications for IBD Research', Gut, 62, pp. A74.1 - A74, http://dx.doi.org/10.1136/gutjnl-2013-304907.164

Kennedy NA; Hildebrand D; Berry SH; Satsangi J; Hold GL, 2013, 'PWE-108 Assessment of the Mucosal Microbiota in Inflammatory Bowel Disease', Gut, 62, pp. A174.2 - A175, http://dx.doi.org/10.1136/gutjnl-2013-304907.396

Hold GL; Hope M; Lochhead P; Meharg C; Berry SH; El-Omar E, 2013, 'Sa1972 Assessment of Bacterial Diversity in Colorectal Adenomatous Polyps', Gastroenterology, 144, pp. S - 348, http://dx.doi.org/10.1016/s0016-5085(13)61281-0

Hansen R; Mukhopadhya I; Meharg C; Russell RK; Berry SH; El-Omar E; Hold GL, 2013, 'Tu1704 The Role of the Fungal Microbiota in the Pathogenesis of De-Novo Pediatric Inflammatory Bowel Disease Using Next Generation Sequencing', Gastroenterology, 144, pp. s - 826, http://dx.doi.org/10.1016/s0016-5085(13)63068-1

Kennedy NA; Walker A; IBD Microbiota Consortia UK; IBD Genetics Consortia UK; Berry SH; Duncan SH; Farquharson F; Louis P; Satsangi J; Flint HJ; Lees CW; Hold GL, 2013, 'Tu1716 Evaluation of the Impact of Different Commercially Available DNA Extraction Kits and Laboratories for Assessing Bacterial Community Structure in Fecal Samples - Implications for IBD Research', Gastroenterology, 144, pp. S - 829, http://dx.doi.org/10.1016/s0016-5085(13)63080-2

Watt E; Berry SH; Farquharson F; Glaire MA; Thomson JM; El-Omar E; Louis P; Hold GL, 2013, 'Tu1729 Evaluation of Fecal Aspirate As a Proxy for Colonoscopy Biopsy Sampling to Assess Microbial Diversity', Gastroenterology, 144, pp. S - 832, http://dx.doi.org/10.1016/s0016-5085(13)63093-0

Hansen R; Russell RK; Reiff C; Louis P; McIntosh F; Berry SH; MGBRhopadhya I; Bisset WM; Barclay AR; Bishop J; Flynn DM; McGrogan P; Loganathan S; Mahdi G; Flint HJ; El-Omar EM; Hold GL, 2012, 'Microbiota of de-novo pediatric IBD: Increased faecalibacterium prausnitzii and reduced bacterial diversity in Crohn's but not in ulcerative colitis', American Journal of Gastroenterology, 107, pp. 1913 - 1922, http://dx.doi.org/10.1038/ajg.2012.335

Smith C; Lochhead P; Basavaraju U; Hold GL; Fyfe N; Murray GI; El-Omar EM, 2012, 'Lack of association between the rs2294008 polymorphism in the prostate stem cell antigen gene and colorectal neoplasia: A case-control and immunohistochemical study', BMC Research Notes, 5, pp. 371, http://dx.doi.org/10.1186/1756-0500-5-371

Palmer AJ; Lochhead P; Hold GL; Rabkin CS; Chow WH; Lissowska J; Vaughan TL; Berry S; Gammon M; Risch H; El-Omar EM, 2012, 'Genetic variation in C20orf54, PLCE1 and MUC1 and the risk of upper gastrointestinal cancers in Caucasian populations', European Journal of Cancer Prevention, 21, pp. 541 - 544, http://dx.doi.org/10.1097/CEJ.0b013e3283529b79

Smith C; Lochhead P; Basavaraju U; Hold G; Fyfe N; Murray G; El-Omar E, 2012, 'LACK OF ASSOCIATION BETWEEN THE PSCA RS2294008 POLYMORPHISM, OR PSCA EXPRESSION, AND COLORECTAL NEOPLASIA', GUT, 61, pp. A327 - A328, http://dx.doi.org/10.1136/gutjnl-2012-302514d.75

Mukhopadhya I; Hansen R; El-Omar EM; Hold GL, 2012, 'IBD-what role do Proteobacteria play?', Nature Reviews Gastroenterology and Hepatology, 9, pp. 219 - 230, http://dx.doi.org/10.1038/nrgastro.2012.14

Hird HJ; Chisholm J; Kaye J; Colyer A; Hold G; Conyers CM; Núñez JI; Macarthur R, 2012, 'Development of real-time PCR assays for the detection of Atlantic cod (Gadus morhua), Atlantic salmon (Salmo salar) and European plaice (Pleuronectes platessa) in complex food samples', European Food Research and Technology, 234, pp. 127 - 136, http://dx.doi.org/10.1007/s00217-011-1596-4

Raju D; Hussey S; Ang M; Terebiznik MR; Sibony M; Galindo-Mata E; Gupta V; Blanke SR; Delgado A; Romero-Gallo J; Ramjeet MS; Mascarenhas H; Peek RM; Correa P; Streutker C; Hold G; Kunstmann E; Yoshimori T; Silverberg MS; Girardin SE; Philpott DJ; El Omar E; Jones NL, 2012, 'Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote helicobacter pylori infection in humans', Gastroenterology, 142, pp. 1160 - 1171, http://dx.doi.org/10.1053/j.gastro.2012.01.043

Palmer AJ; Lochhead P; Hold GL; Rabkin CS; Vaughan TL; Lissowska J; Chow W-H; Berry SH; El-Omar E, 2012, 'Mo1584 Genetic Variation in C20orf54, PLCE1 and MUC1 and Risk of Upper Gastrointestinal Cancers in Caucasian Populations', Gastroenterology, 142, pp. S - 634, http://dx.doi.org/10.1016/s0016-5085(12)62439-1

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