By Professor Georgina Hold

Journal articles

Kennedy N; Walker A; Berry S; Duncan S; Farquharson F; Louis P; Satsangi J; Flint H; Lees C; Hold G, 2013, 'PTU-072 Evaluation of the Impact of different Commercially available DNA Extraction Kits and Laboratories for Assessing Bacterial Community Structure in Faecal Samples – Implications for IBD Research', Gut, 62, pp. A74.1 - A74, http://dx.doi.org/10.1136/gutjnl-2013-304907.164

Kennedy NA; Hildebrand D; Berry SH; Satsangi J; Hold GL, 2013, 'PWE-108 Assessment of the Mucosal Microbiota in Inflammatory Bowel Disease', Gut, 62, pp. A174.2 - A175, http://dx.doi.org/10.1136/gutjnl-2013-304907.396

Hold GL; Hope M; Lochhead P; Meharg C; Berry SH; El-Omar E, 2013, 'Sa1972 Assessment of Bacterial Diversity in Colorectal Adenomatous Polyps', Gastroenterology, 144, pp. S - 348, http://dx.doi.org/10.1016/s0016-5085(13)61281-0

Hansen R; Mukhopadhya I; Meharg C; Russell RK; Berry SH; El-Omar E; Hold GL, 2013, 'Tu1704 The Role of the Fungal Microbiota in the Pathogenesis of De-Novo Pediatric Inflammatory Bowel Disease Using Next Generation Sequencing', Gastroenterology, 144, pp. S - 826, http://dx.doi.org/10.1016/s0016-5085(13)63068-1

Kennedy NA; Walker A; IBD Microbiota Consortia UK; IBD Genetics Consortia UK; Berry SH; Duncan SH; Farquharson F; Louis P; Satsangi J; Flint HJ; Lees CW; Hold GL, 2013, 'Tu1716 Evaluation of the Impact of Different Commercially Available DNA Extraction Kits and Laboratories for Assessing Bacterial Community Structure in Fecal Samples - Implications for IBD Research', Gastroenterology, 144, pp. S - 829, http://dx.doi.org/10.1016/s0016-5085(13)63080-2

Watt E; Berry SH; Farquharson F; Glaire MA; Thomson JM; El-Omar E; Louis P; Hold GL, 2013, 'Tu1729 Evaluation of Fecal Aspirate As a Proxy for Colonoscopy Biopsy Sampling to Assess Microbial Diversity', Gastroenterology, 144, pp. S - 832, http://dx.doi.org/10.1016/s0016-5085(13)63093-0

Hansen R; Russell RK; Reiff C; Louis P; McIntosh F; Berry SH; MGBRhopadhya I; Bisset WM; Barclay AR; Bishop J; Flynn DM; McGrogan P; Loganathan S; Mahdi G; Flint HJ; El-Omar EM; Hold GL, 2012, 'Microbiota of de-novo pediatric IBD: Increased faecalibacterium prausnitzii and reduced bacterial diversity in Crohn's but not in ulcerative colitis', American Journal of Gastroenterology, 107, pp. 1913 - 1922, http://dx.doi.org/10.1038/ajg.2012.335

Smith C; Lochhead P; Basavaraju U; Hold GL; Fyfe N; Murray GI; El-Omar EM, 2012, 'Lack of association between the rs2294008 polymorphism in the prostate stem cell antigen gene and colorectal neoplasia: A case-control and immunohistochemical study', BMC Research Notes, 5, pp. 371, http://dx.doi.org/10.1186/1756-0500-5-371

Palmer AJ; Lochhead P; Hold GL; Rabkin CS; Chow WH; Lissowska J; Vaughan TL; Berry S; Gammon M; Risch H; El-Omar EM, 2012, 'Genetic variation in C20orf54, PLCE1 and MUC1 and the risk of upper gastrointestinal cancers in Caucasian populations', European Journal of Cancer Prevention, 21, pp. 541 - 544, http://dx.doi.org/10.1097/CEJ.0b013e3283529b79

Smith C; Lochhead P; Basavaraju U; Hold G; Fyfe N; Murray G; El-Omar E, 2012, 'LACK OF ASSOCIATION BETWEEN THE PSCA RS2294008 POLYMORPHISM, OR PSCA EXPRESSION, AND COLORECTAL NEOPLASIA', GUT, 61, pp. A327 - A328, http://dx.doi.org/10.1136/gutjnl-2012-302514d.75

Mukhopadhya I; Hansen R; El-Omar EM; Hold GL, 2012, 'IBD-what role do Proteobacteria play?', Nature Reviews Gastroenterology and Hepatology, 9, pp. 219 - 230, http://dx.doi.org/10.1038/nrgastro.2012.14

Hird HJ; Chisholm J; Kaye J; Colyer A; Hold G; Conyers CM; Núñez JI; Macarthur R, 2012, 'Development of real-time PCR assays for the detection of Atlantic cod (Gadus morhua), Atlantic salmon (Salmo salar) and European plaice (Pleuronectes platessa) in complex food samples', European Food Research and Technology, 234, pp. 127 - 136, http://dx.doi.org/10.1007/s00217-011-1596-4

Raju D; Hussey S; Ang M; Terebiznik MR; Sibony M; Galindo-Mata E; Gupta V; Blanke SR; Delgado A; Romero-Gallo J; Ramjeet MS; Mascarenhas H; Peek RM; Correa P; Streutker C; Hold G; Kunstmann E; Yoshimori T; Silverberg MS; Girardin SE; Philpott DJ; El Omar E; Jones NL, 2012, 'Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote helicobacter pylori infection in humans', Gastroenterology, 142, pp. 1160 - 1171, http://dx.doi.org/10.1053/j.gastro.2012.01.043

Palmer AJ; Lochhead P; Hold GL; Rabkin CS; Vaughan TL; Lissowska J; Chow W-H; Berry SH; El-Omar E, 2012, 'Mo1584 Genetic Variation in C20orf54, PLCE1 and MUC1 and Risk of Upper Gastrointestinal Cancers in Caucasian Populations', Gastroenterology, 142, pp. S - 634, http://dx.doi.org/10.1016/s0016-5085(12)62439-1

Hansen R; El-Omar E; Hold GL, 2011, 'Characterizing the microbiota in IBD', Inflammatory Bowel Disease Monitor, 12, pp. 1 - 7

Mukhopadhya I; Hansen R; Nicholl CE; Alhaidan YA; Thomson JM; Berry SH; Pattinson C; Stead DA; Russell RK; El-Omar EM; Hold GL, 2011, 'A comprehensive evaluation of colonic mucosal isolates of sutterella wadsworthensis from inflammatory bowel disease', PLoS ONE, 6, pp. e27076, http://dx.doi.org/10.1371/journal.pone.0027076

Smet A; Flahou B; Mukhopadhya I; Ducatelle R; Pasmans F; Haesebrouck F; Hold GL, 2011, 'The Other Helicobacters', Helicobacter, 16, pp. 70 - 75, http://dx.doi.org/10.1111/j.1523-5378.2011.00884.x

Mukhopadhya I; Thomson JM; Hansen R; Berry SH; El-Omar EM; Hold GL, 2011, 'Detection of Campylobacter concisus and other campylobacter species in colonic biopsies from adults with ulcerative colitis', PLoS ONE, 6, pp. e21490, http://dx.doi.org/10.1371/journal.pone.0021490

Monie TP; Hold GL; Mukhopadhya I, 2011, 'Innate immune sensors and gastrointestinal bacterial infections', Clinical and Developmental Immunology, 2011, http://dx.doi.org/10.1155/2011/579650

Haag AF; Wehmeier S; Muszyński A; Kerscher B; Fletcher V; Berry SH; Hold GL; Carlson RW; Ferguson GP, 2011, 'Biochemical characterization of Sinorhizobium meliloti mutants reveals gene products involved in the biosynthesis of the unusual lipid A very long-chain fatty acid', Journal of Biological Chemistry, 286, pp. 17455 - 17466, http://dx.doi.org/10.1074/jbc.M111.236356

Thomson JM; Hansen R; Berry SH; Hope ME; Murray GI; Mukhopadhya I; McLean MH; Shen Z; Fox JG; El-Omar E; Hold GL, 2011, 'Enterohepatic Helicobacter in ulcerative colitis: Potential pathogenic entities?', PLoS ONE, 6, pp. e17184, http://dx.doi.org/10.1371/journal.pone.0017184

Hansen R; Thomson JM; Fox JG; El-Omar EM; Hold GL, 2011, 'Could Helicobacter organisms cause inflammatory bowel disease?', FEMS Immunology and Medical Microbiology, 61, pp. 1 - 14, http://dx.doi.org/10.1111/j.1574-695X.2010.00744.x

McLean MH; Murray GI; Stewart KN; Norrie G; Mayer C; Hold GL; Thomson J; Fyfe N; Hope M; Mowat NAG; Drew JE; El-Omar EM, 2011, 'The inflammatory microenvironment in colorectal Neoplasia', PLoS ONE, 6, pp. e15366, http://dx.doi.org/10.1371/journal.pone.0015366

Lochhead P; Frank B; Hold GL; Rabkin CS; Ng MTH; Vaughan TL; Risch HA; Gammon MD; Lissowska J; Weck MN; Raum E; Mller H; Illig T; Klopp N; Dawson A; McColl KE; Brenner H; Chow W; Elomar EM, 2011, 'Genetic variation in the prostate stem cell antigen gene and upper gastrointestinal cancer in white individuals', Gastroenterology, 140, pp. 435 - 441, http://dx.doi.org/10.1053/j.gastro.2010.11.001

Lochhead P; Ng MTH; Hold GL; Rabkin CS; Vaughan TL; Gammon MD; Risch HA; Lissowska J; Mukhopadhya I; Chow WH; El-Omar EM, 2011, 'Possible association between a genetic polymorphism at 8q24 and risk of upper gastrointestinal cancer', European Journal of Cancer Prevention, 20, pp. 54 - 57, http://dx.doi.org/10.1097/CEJ.0b013e328341e320

Hansen R; Reiff C; Russell RK; Bisset WM; Berry SH; Mukhopadhya I; Thomson JM; El-Omar E; Hold GL, 2011, 'Bacterial Diversity of the Colonic Microbiota in De-Novo Extensive Paediatric Ulcerative Colitis by Next-Generation Sequencing', Gastroenterology, 140, pp. S - 196, http://dx.doi.org/10.1016/s0016-5085(11)60792-0

Goddard M; Hansen R; Karcher AM; Munro MJ; Berry SH; Stevenson MH; El-Omar E; Hold GL, 2011, 'Bilirubin Has Anti-Bacterial Properties Against Gram-Positive Bacteria: A Potential Benefit of Physiological Jaundice?', Gastroenterology, 140, pp. S - 941, http://dx.doi.org/10.1016/s0016-5085(11)63902-4

Mukhopadhya I; Thomson JM; Hansen R; Berry SH; El-Omar E; Hold GL, 2011, 'Detection of Campylobacter Concisus in Colonic Biopsies From Adult Patients With Ulcerative Colitis', Gastroenterology, 140, pp. S - 268, http://dx.doi.org/10.1016/s0016-5085(11)61073-1

Hansen R; Mukhopadhya I; Russell RK; Bisset WM; Berry SH; Thomson JM; El-Omar E; Hold GL, 2011, 'The Role of the Microaerophilic Colonic Microbiota in De-Novo Paediatric Inflammatory Bowel Disease', Gastroenterology, 140, pp. S - 512, http://dx.doi.org/10.1016/s0016-5085(11)62122-7

Hansen R; Cameron FL; Hold GL; El-Omar EM; Russell RK, 2010, 'Inflammatory bowel disease', Paediatrics and Child Health, 20, pp. 473 - 478, http://dx.doi.org/10.1016/j.paed.2010.04.005

Ng MTH; Van't Hof R; Crockett JC; Hope ME; Berry S; Thomson J; McLean MH; McColl KEL; El-Omar EM; Hold GL, 2010, 'Increase in NF-κB binding affinity of the variant C allele of the toll-like receptor 9 -1237T/C polymorphism is associated with Helicobacter pylori-induced gastric disease', Infection and Immunity, 78, pp. 1345 - 1352, http://dx.doi.org/10.1128/IAI.01226-09

Hansen R; Thomson JM; El-Omar EM; Hold GL, 2010, 'The role of infection in the aetiology of inflammatory bowel disease', Journal of Gastroenterology, 45, pp. 266 - 276, http://dx.doi.org/10.1007/s00535-009-0191-y

FitzGerald MP; Wehmeier S; Gangloff M; Gay N; Berry SH; Ferguson GP; El-Omar E; Hold GL, 2010, 'S1640 Can Helicobacter pylori Lipopolysaccharide Lipid a Composition Affect Its Ability to Induce an Inflammatory Response Through Toll Like Receptor 4', Gastroenterology, 138, pp. S - 244, http://dx.doi.org/10.1016/s0016-5085(10)61110-9

Saunders KA; Crockett JC; Berry SH; El-Omar E; Hold GL, 2010, 'S1641 Impact of the TLR4 Asp299Gly Polymorphism on Induction of the Inflammatory Response Following H. pylori Infection', Gastroenterology, 138, pp. S - 244, http://dx.doi.org/10.1016/s0016-5085(10)61111-0

Ng MT; Rabkin CS; Lochhead P; Lissowska J; Vaughan TL; Gammon M; Risch H; Chow W-H; Hold GL; El-Omar E, 2010, 'T2009 Assessment of Novel Genetic Polymorphisms and Risk of Upper Gastrointestinal Carcinoma', Gastroenterology, 138, pp. S - 612, http://dx.doi.org/10.1016/s0016-5085(10)62822-3

Basavaraju U; Shebl FM; Palmer AJ; Hold GL; Rabkin CS; El-Omar E, 2010, 'T2012 Cytokine Gene Polymorphisms, Cytokine Levels and Risk of Colorectal Neoplasia in the Screened Population of Northeast Scotland', Gastroenterology, 138, pp. S - 613, http://dx.doi.org/10.1016/s0016-5085(10)62825-9

El-Sakka NE; Hold GL; El-Omar E, 2010, 'W1738 Role of TLR4 in Carcinogenesis and Tumor Progression of Colorectal Cancer', Gastroenterology, 138, pp. S - 730, http://dx.doi.org/10.1016/s0016-5085(10)63358-6

Hold GL; Untiveros P; Saunders KA; El-Omar EM, 2009, 'Role of host genetics in fibrosis', Fibrogenesis and Tissue Repair, 2, pp. 6, http://dx.doi.org/10.1186/1755-1536-2-6

Hansen R; Hold GL; Berry SH; El Sakka NE; Thomson J; Bisset WM; Mahdi G; Murray GI; Helms PJ; El-Omar E, 2009, 'Are non-Pylori Helicobacter Organisms Associated with Paediatric Ulcerative Colitis? A Retrospective Observational Study', SCOTTISH MEDICAL JOURNAL, 54, pp. 54 - 55, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000272538800039&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hold GL; Rabkin CS; Gammon MD; Berry SH; Smith MG; Lissowska J; Risch HA; Chow WH; Ashley G Mowat N; Vaughan TL; El-Omar EM, 2009, 'CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations', European Journal of Cancer Prevention, 18, pp. 117 - 119, http://dx.doi.org/10.1097/CEJ.0b013e3283101292

Hansen R; El-Sakka NE; Berry SH; Thomson JM; Bisset WM; Mahdi G; Murray GI; Helms PJ; Hold G; El-Omar EM, 2009, 'W1180 Are Non-Pylori Helicobacter Organisms Associated with Paediatric Ulcerative Colitis? Retrospective Observational Study', Gastroenterology, 136, pp. A - 671, http://dx.doi.org/10.1016/s0016-5085(09)63093-6

McLean MH; Murray GI; Fyfe N; Hold GL; Mowat NAG; El-Omar EM, 2008, 'COX-2 expression in sporadic colorectal adenomatous polyps is linked to adenoma characteristics', Histopathology, 52, pp. 806 - 815, http://dx.doi.org/10.1111/j.1365-2559.2008.03038.x

Ng MT; Crockett JC; Van't Hof R; Berry SH; El-Omar E; Hold G, 2008, 'A single nucleotide polymorphism in the TLR9 promoter (TLR9-1237T/C) increases the affinity of NF-kappa B protein binding and enhances transcriptional activity upon H-pylori infection', GASTROENTEROLOGY, 134, pp. A567 - A567, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255101504189&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

McLean MH; Drew JE; Mayer CD; Farquharson A; Barrera LN; Fyfe N; Murray GI; Hold G; Mowat NA; El-Omar E, 2008, 'Role of chronic inflammation in sporadic colorectal neoplasia', GASTROENTEROLOGY, 134, pp. A293 - A294, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255101502155&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Thomson JM; Hold G; Berry SH; El-Sakka NE; Mowat NA; Shen Z; Taylor NS; Fox JG; El-Omar E, 2008, 'Variable detection of entero-hepatic Helicobacter species in colonic mucosal pinch biopsies by different molecular techniques', GASTROENTEROLOGY, 134, pp. A655 - A655, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255101504599&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hold GL; El-Omar EM, 2008, 'Genetic aspects of inflammation and cancer', Biochemical Journal, 410, pp. 225 - 235, http://dx.doi.org/10.1042/BJ20071341

El-Omar EM; Ng MT; Hold GL, 2008, 'Polymorphisms in Toll-like receptor genes and risk of cancer', Oncogene, 27, pp. 244 - 252, http://dx.doi.org/10.1038/sj.onc.1210912

McLean MH; Drew JE; Mayer CD; Farquharson A; Barrera LN; Fyfe N; Murray GI; Hold G; Mowat NA; El-Omar E, 2008, 'S1996 Role of Chronic Inflammation in Sporadic Colorectal Neoplasia', Gastroenterology, 134, http://dx.doi.org/10.1016/s0016-5085(08)61366-9

Ng MT; Crockett JC; Van't Hof R; Berry SH; El-Omar E; Hold G, 2008, 'T1807 A Single Nucleotide Polymorphism in the TLR9 Promoter (TLR9 −1237T/C) Increases the Affinity of NF-κB Protein Binding and Enhances Transcriptional Activity Upon H. pylori Infection', Gastroenterology, 134, pp. A - 567, http://dx.doi.org/10.1016/s0016-5085(08)62648-7

Thomson JM; Hold G; Berry SH; El-Sakka NE; Mowat NA; Shen Z; Taylor NS; Fox JG; El-Omar E, 2008, 'W1208 Variable Detection of Entero-Hepatic Helicobacter Species in Colonic Mucosal Pinch Biopsies By Different Molecular Techniques', Gastroenterology, 134, pp. A - 655, http://dx.doi.org/10.1016/s0016-5085(08)63058-9

Back to profile page