By Professor Johannes le Coutre

Journal articles

Menozzi C; Riera CE; Munari C; Coutre JL; Robert F, 2009, 'Synthesis and evaluation of new alkylamides derived from α-hydroxysanshool, the pungent molecule in szechuan pepper', Journal of Agricultural and Food Chemistry, 57, pp. 1982 - 1989, http://dx.doi.org/10.1021/jf803067r

Riera CE; Vogel H; Simon SA; Damak S; Coutre JL, 2009, 'Sensory attributes of complex tasting divalent salts are mediated by TRPM5 and TRPV1 channels', Journal of Neuroscience, 29, pp. 2654 - 2662, http://dx.doi.org/10.1523/JNEUROSCI.4694-08.2009

Toepel U; Knebel JF; Hudry J; le Coutre J; Murray MM, 2009, 'The brain tracks the energetic value in food images', NeuroImage, 44, pp. 967 - 974, http://dx.doi.org/10.1016/j.neuroimage.2008.10.005

Riera CE; Vogel H; Simon SA; Damak S; le Coutre J, 2008, 'The capsaicin receptor participates in artificial sweetener aversion', Biochemical and Biophysical Research Communications, 376, pp. 653 - 657, http://dx.doi.org/10.1016/j.bbrc.2008.09.029

Coutre JL; Schmitt JAJ, 2008, 'Food ingredients and cognitive performance', Current Opinion in Clinical Nutrition and Metabolic Care, 11, pp. 706 - 710, http://dx.doi.org/10.1097/MCO.0b013e32831394a5

Bezençon C; Fürholz A; Raymond F; Mansourian R; Métairon S; Le Coutre J; Damak S, 2008, 'Murine intestinal cells expressing Trpm5 are mostly brush cells and express markers of neuronal and inflammatory cells', Journal of Comparative Neurology, 509, pp. 514 - 525, http://dx.doi.org/10.1002/cne.21768

Knebel JF; Toepel U; Hudry J; Le Coutre J; Murray MM, 2008, 'Generating controlled image sets in cognitive neuroscience research', Brain Topography, 20, pp. 284 - 289, http://dx.doi.org/10.1007/s10548-008-0046-5

Michlig S; Le Contre J, 2008, 'Salt, taste and health', Food Science and Technology, 22, pp. 16 - 18

Blum S; German B; van Bladeren P; le Coutre J, 2008, 'Translating research into action: nutritional strategies for the cancer patient', Nature, 452, https://www.nature.com/nature/supplements/insights/cancerdiagnostics/pdf/nestle-white-paper-Mar-08.pdf?origin=ppub

Damak S; Le Coutre J, 2008, 'Molecular taste physiology of tongue and gut', Agro Food Industry Hi-Tech, 19, pp. 58 - 60

Riera CE; Vogel H; Simon SA; Le Coutre J, 2007, 'Artificial sweeteners and salts producing a metallic taste sensation activate TRPV1 receptors', American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 293, http://dx.doi.org/10.1152/ajpregu.00286.2007

Michlig S; Damak S; Le Coutre J, 2007, 'Claudin-based permeability barriers in taste buds', Journal of Comparative Neurology, 502, pp. 1003 - 1011, http://dx.doi.org/10.1002/cne.21354

Bezençon C; le Coutre J; Damak S, 2007, 'Taste-signaling proteins are coexpressed in solitary intestinal epithelial cells', Chemical Senses, 32, pp. 41 - 49, http://dx.doi.org/10.1093/chemse/bjl034

Parry CM; Erkner A; Le Coutre J, 2004, 'Divergence of T2R chemosensory receptor families in humans, bonobos, and chimpanzees', Proceedings of the National Academy of Sciences of the United States of America, 101, pp. 14830 - 14834, http://dx.doi.org/10.1073/pnas.0404894101

Rossier O; Cao J; Huque T; Spielman AI; Feldman RS; Medrano JF; Brand JG; le Coutre J, 2004, 'Analysis of a human fungiform papillae cDNA library and identification of taste-related genes', Chemical Senses, 29, pp. 13 - 23, http://dx.doi.org/10.1093/chemse/bjh002

le Coutre J, 2003, 'Disappointed by errors - Reply', FOOD TECHNOLOGY, 57, pp. 80 - 81, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000186685800025&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Le Coutre J, 2003, 'Taste: The metabolic sense', Food Technology, 57, pp. 34 - 39

Le Coutre J; Turk E; Kaback HR; Wright EM, 2002, 'Ligand-induced differences in secondary structure of the Vibrio parahaemolyticus Na⁺/galactose cotransporter', Biochemistry, 41, pp. 8082 - 8086, http://dx.doi.org/10.1021/bi025692d

Whitelegge JP; le Contre J, 2001, 'Proteomics. Making sense of genomic information for drug discovery', American journal of pharmacogenomics: genomics-related research in drug development and clinical practice, 1, pp. 29 - 35, http://dx.doi.org/10.2165/00129785-200101010-00004

Coutre JL; Ronald Kaback H, 2000, 'Structure-function relationships of integral membrane proteins: Membrane transporters vs channels', Biopolymers - Peptide Science Section, 55, pp. 297 - 307, http://dx.doi.org/10.1002/1097-0282(2000)55:4<297::AID-BIP1003>3.0.CO;2-H

Turk E; Kim O; Le Coutre J; Whitelegge JP; Eskandari S; Lam JT; Kreman M; Zampighi G; Faull KF; Wright EM, 2000, 'Molecular characterization of Vibrio parahaemolyticus vSGLT. A model for sodium-coupled sugar cotransporters', Journal of Biological Chemistry, 275, pp. 25711 - 25716, http://dx.doi.org/10.1074/jbc.M003127200

Le Coutre J; Whitelegge JP; Gross A; Turk E; Wright EM; Kaback HR; Faull KF, 2000, 'Proteomics on full-length membrane proteins using mass spectrometry', Biochemistry, 39, pp. 4237 - 4242, http://dx.doi.org/10.1021/bi000150m

Whitelegge JP; Le Coutre J; Lee JC; Engel CK; Privé GG; Faull KF; Kaback HR, 1999, 'Toward the bilayer proteome, electrospray ionization-mass spectrometry of large, intact transmembrane proteins', Proceedings of the National Academy of Sciences of the United States of America, 96, pp. 10695 - 10698, http://dx.doi.org/10.1073/pnas.96.19.10695

Sahin-Tóth M; Le Coutre J; Kharabi D; Le Maire G; Lee JC; Kaback HR, 1999, 'Characterization of Glu126 and Arg144, two residues that are indispensable for substrate binding in the lactose permease of Escherichia coli', Biochemistry, 38, pp. 813 - 819, http://dx.doi.org/10.1021/bi982200h

Le Coutre J; Kaback HR; Patel CKN; Heginbotham L; Miller C, 1998, 'Fourier transform infrared spectroscopy reveals a rigid α-helical assembly for the tetrameric Streptomyces lividans K⁺ channel', Proceedings of the National Academy of Sciences of the United States of America, 95, pp. 6114 - 6117, http://dx.doi.org/10.1073/pnas.95.11.6114

Le Coutre J; Narasimhan LR; Patel CKN; Kaback HR, 1997, 'The lipid bilayer determines helical tilt angle and function in lactose permease of Escherichia coli', Proceedings of the National Academy of Sciences of the United States of America, 94, pp. 10167 - 10171, http://dx.doi.org/10.1073/pnas.94.19.10167

le Coutre J; Narasimhan LR; Patel CKN; Kaback HR, 1997, 'ATR-FTIR spectroscopy on the Lactose Permease of E. coli', Biophysical Journal, 72, pp. TH343 - TH343

Le Coutre J; Gerwert K, 1996, 'Kinetic isotope effects reveal an ice-like and a liquid-phase-type intramolecular proton transfer in bacteriorhodopsin', FEBS Letters, 398, pp. 333 - 336, http://dx.doi.org/10.1016/S0014-5793(96)01254-9

le Coutre J, 1996, 'The molecular reaction mechanism of a membrane protein', Futura

Le Coutre J; Tittor J; Oesterhelt D; Gerwert K, 1995, 'Experimental evidence for hydrogen-bonded network proton transfer in bacteriorhodopsin shown by Fourier-transform infrared spectroscopy using azide as catalyst', Proceedings of the National Academy of Sciences of the United States of America, 92, pp. 4962 - 4966, http://dx.doi.org/10.1073/pnas.92.11.4962

le Coutre J; Rüdiger M; Oesterhelt D; Gerwert K, 1995, 'FTIR investigation of the blue to acid-purple transition of Bacteriorhodopsin by use of induced halide binding', Journal of Molecular Structure, 349, pp. 165 - 168, http://dx.doi.org/10.1016/0022-2860(95)08735-E

Schütz M; Zirngibl S; le Coutre J; Büttner M; Xie DL; Nelson N; Deutzmann R; Hauska G, 1994, 'A transcription unit for the Rieske FeS-protein and cytochrome b in Chlorobium limicola', Photosynthesis Research, 39, pp. 163 - 174, http://dx.doi.org/10.1007/BF00029383

Zirngibl S; Xie D; Riedel A; Nitschke W; Nelson H; Nelson N; Liebl U; le Coutre J; Hauska G; Kellner E; Groditzki D; Buettner M, 1992, 'Low Potential Rieske FeS-Centers of Menaquinol oxidizing Cytochrome bc-complexes', Research in Photosynthesis, 2, pp. 471 - 478

Patents

Gonzalez S; Merlini J; Camacho S; le Coutre J, 2019, Compositions and methods using P-anisaldehyde, Patent No. US-9931308-B2

Actis G; Patin A; Gonzalez S; Camacho S; Legrand C; le Coutre J; Castaneda E; Zolezzi I, 2017, Compositions comprising 3'-oglucuronide epicatechin and methods of making and using such compositions, Patent No. WO2017102965-A1

Actis G; Amaury P; Gonzalez S; Legrand C; Camacho S; le Coutre J, 2016, Compositions comprising 3'-omethyl-4'-o-sulfate epicatechin and therapeutic uses of such compositions, Patent No. WO2017129421-A1

Actis G; Amaury P; Gonzalez S; LeGrand C; le Coutre J; Camacho S, 2016, Compositions comprising 3'-omethyl-5-o-sulfate epicatechin and therapeutic uses of such compositions, Patent No. WO2017129422-A1

le Coutre J; Actis G; Patin A; Gonzalez S; Gutierrez E; Zolezzi I, 2015, Compositions comprising 4'-oglucuronide epicatechin and methods of making and using such compositions, Patent No. WO2017102968-A1

Camacho S; Gonzalez S; Actis G; Merlini J; le Coutre J, 2015, Compositions comprising cinnamaldehyde and zinc and methods of using such compositions, Patent No. CA-2985564-A1

Gonzalez S; Beaumont M; le Coutre J, 2014, Methods using facial temperature to evaluate postingestive impact of food ingredients on fat oxidation, Patent No. US-2017367588A1

Gonzalez S; Merlini J; Camacho S; le Coutre J, 2014, Compositions comprising cinnamaldehyde and zinc and methods of using such compositions, Patent No. US-2017164648A1

Gonzalez S; Merlini J; Burbidge A; le Coutre J, 2014, Composition comprising cinnamaldehyde and zinc to improve swallowing, Patent No. US-2017224729A1

Gonzalez S; Merlini J; Burbridge A; le Coutre J, 2014, Methods and compositions for using cinnamaldehyde and zinc for weight management, Patent No. US-2016339058A1

Gonzalez S; le Coutre J, 2013, Methods and compositions for increasing energy expenditure using cinnamaldehyde, Patent No. US-2016303055A1

Gonzalez S; Merlini J; Camacho S; le Coutre J, 2013, Compositions and methods using cuminaldehyde, Patent No. US-9867790-B2

Gonzalez S; Merlini J; Camacho S; le Coutre J, 2013, Compositions and methods using p-anisaldehyde, Patent No. US-2016175264A1

Gonsalez S; Merlini J; Camacho S; le Coutre J, 2013, Compositions and methods using tiglic aldehyde, Patent No. US-9801833-B2

Camacho S; Gonzalez S; le Coutre J; Markram H; Pezzoli M, 2013, Treatment or prevention of autism disorders using menthol, linalool and/or icilin, Patent No. US-2016089370A1

Camacho S; Gonzalez S; le Coutre J; Markram H; Pezzoli M, 2013, Treatment or prevention of depression using menthol and/or icilin, Patent No. US-2016108005A1

Camacho S; Gonzalez S; le Coutre J; Markram H; Pezzoli M, 2013, Treatment or prevention of neurodegenerative disorders using menthol, linalool and/or icilin, Patent No. US-2016108004A1

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