Select Publications
Journal articles
1997, 'Synthesis of 6,7-benz[c]acephenanthrylene and its photodimerization to a simple molecular tweezer', Synthesis, pp. 506 - 508, http://dx.doi.org/10.1055/s-1997-1233
,1996, 'The development of more efficient syntheses of polycyclic diterpenes through intramolecular cyclopropanation of aryl rings in diazomethyl ketones', Pure and Applied Chemistry, 68, pp. 515 - 522, http://dx.doi.org/10.1351/pac199668030515
,1996, 'Dibenzotetraphenylperiflanthene: Synthesis, Photophysical Properties, and Electrogenerated Chemiluminescence', Journal of the American Chemical Society, 118, pp. 2374 - 2379, http://dx.doi.org/10.1021/ja9537888
,Conference Papers
2020, 'CLK inhibition alters tau splicing and has a neuroprotective effect in vitro', in Alzheimer's & Dementia, Wiley, http://dx.doi.org/10.1002/alz.042805
,2019, 'Designing topical VEGF-A inhibitors with high retinal bioavailability using ex vivo permeability modelling', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, CANADA, Vancouver, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), CANADA, Vancouver, 28 April 2019 - 02 May 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000488628108002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2019, 'EXN407, a novel topical therapeutic candidate with high retinal bioavailability for the treatment of diabetic macular oedema, inhibits ocular neovascularisation', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, CANADA, Vancouver, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), CANADA, Vancouver, 28 April 2019 - 02 May 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000488628100027&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2019, 'Wnt5A Dependent Revascularisation After Ischemia Is SRPK1 Dependent', in JOURNAL OF VASCULAR RESEARCH, KARGER, NETHERLANDS, Maastricht, pp. 14 - 14, presented at 3rd Joint Meeting of the European-Society-for-Microcirculation (ESM) and the European-Vascular-Biology-Organization (EVBO), NETHERLANDS, Maastricht, 15 April 2019 - 18 April 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000463529300031&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2018, 'A novel approach to inhibit pro-angiogenic VEGF splicing in retinal vascular diseases with topical administration of small molecules optimised for retinal pharmacokinetics', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, HI, Honolulu, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), HI, Honolulu, 29 April 2018 - 03 May 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000442912500186&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2017, 'Endothelial-targeted Nitroxides Inhibit MPO-mediated Endothelial Dysfunction', in FREE RADICAL BIOLOGY AND MEDICINE, ELSEVIER SCIENCE INC, MD, Baltimore, pp. 207 - 207, presented at 24th Annual Meeting of the Society-for-Redox-Biology-and-Medicine (SfRBM), MD, Baltimore, 29 November 2017 - 02 December 2017, http://dx.doi.org/10.1016/j.freeradbiomed.2017.10.328
,2017, 'Novel PP2A Inhibitory Protein in C-KIT Mutant Myeloid Progenitor Cells', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 7 - 8, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000413952600003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2017, 'Optimisation of potent SRPK1 inhibitors through modelling of permeability properties required for trans-scleral eye drop delivery', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, MD, Baltimore, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO) - Imaging in the Eye, MD, Baltimore, 06 May 2017 - 11 May 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000432170305102&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2017, 'Targeting SRPK1 with novel potent and selective small molecule inhibitors inhibits choroidal neovascularisation through modulating VEGF-A alternative splicing', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, MD, Baltimore, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO) - Imaging in the Eye, MD, Baltimore, 06 May 2017 - 11 May 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000432170301030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2016, 'Development of topically administered retinal angiogenesis inhibitors with improved ocular permeability and therapeutic exposure in rabbit eyes', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, WA, Seattle, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), WA, Seattle, 01 May 2016 - 05 May 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000394174002193&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2015, 'Development of SRPK1 inhibitors as novel anti-angiogenic therapeutics for exudative age-related macular degeneration (AMD)', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, CO, Denver, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), CO, Denver, 03 May 2015 - 07 May 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000362882206047&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2013, 'Unraveling the mechanism of action: drugs that activate the tumor suppressor 2A.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-2038
,2006, 'Contributions of conformational flexibility to Brugia malayi asparaginyl-tRNA synthetase specificity for inhibitors identified by structure-based screening', in ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, GA, Atlanta, presented at 231st National Meeting of the American-Chemical-Society, GA, Atlanta, 26 March 2006 - 30 March 2006, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000238125903697&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,Conference Abstracts
2017, 'THE E3 UBIQUITIN LIGASE MID1 PROMOTES IDIOPATHIC PULMONARY FIBROSIS', in RESPIROLOGY, WILEY, Vol. 22, pp. 168 - 168, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000396791000311&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2015, 'Inhibition of Myeloperoxidase-Mediated Endothelial Dysfunction by Nitroxides', in FREE RADICAL BIOLOGY AND MEDICINE, ELSEVIER SCIENCE INC, GERMANY, Stuttgart, Vol. 86, pp. S28 - S29, presented at SFRR-E/SNFS Conference, GERMANY, Stuttgart, 02 September 2015 - 04 September 2015, http://dx.doi.org/10.1016/j.freeradbiomed.2015.07.103
,Patents
2023, Nicotinamide riboside analogs, pharmaceutical compositions, and uses thereof, Australia, Patent No. 2019214858
,2021, Nicotinamide riboside analogs, pharmaceutical compositions, and uses thereof, Patent No. US pat no. 11180521
,2019, Piperazine derivatives for treating disorders, Patent No. 6579714
,Preprints
2024, The splicing factor kinase SRPK1 is a therapeutic target for Peripheral Vascular Disease, http://dx.doi.org/10.1101/2024.04.17.589996
,2023, Mitochondrial electron transport chain, ceramide and Coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle., http://dx.doi.org/10.1101/2023.03.10.532020
,2023, Inhibition ofCERS1in skeletal muscle exacerbates age-related muscle dysfunction, http://dx.doi.org/10.1101/2023.08.05.552113
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