By Professor Jonathan Morris

Journal articles

Comber MF; Morris JC; Sargent MV, 1998, 'Synthesis of some 1,2,3,8-tetrasubstituted naphthalenes', Australian Journal of Chemistry, 51, pp. 19 - 22, http://dx.doi.org/10.1071/C97190

Pour M; King GR; Monck NJT; Morris JC; Zhang H; Mander LN, 1998, 'Synthetic and structural studies on novel gibberellins', Pure and Applied Chemistry, 70, pp. 351 - 354, http://dx.doi.org/10.1351/pac199870020351

Mander LN; Morris JC, 1997, 'Application of the sharpless asymmetric dihydroxylation methodology to the enantioselective preparation of 2,3-dihydroxytetrahydro-2-naphthoic esters', Journal of Organic Chemistry, 62, pp. 7497 - 7499, http://dx.doi.org/10.1021/jo970873k

KING GR; MANDER LN; MONCK NJT; MORRIS JC; ZHANG H, 1997, 'ChemInform Abstract: A New and Efficient Strategy for the Total Synthesis of Polycyclic Diterpenoids: The Preparation of Gibberellins (.+‐.)‐GA103 and (.+‐.)‐ GA73.', ChemInform, 28, http://dx.doi.org/10.1002/chin.199733253

King GR; Mander LN; Monck NJT; Morris JC; Zhang H, 1997, 'A new and efficient strategy for the total synthesis of polycyclic diterpenoids: The preparation of gibberellins (±)-GA103 and (±)-GA73', Journal of the American Chemical Society, 119, pp. 3828 - 3829, http://dx.doi.org/10.1021/ja963935h

Debad JD; Morris JC; Magnus P; Bard AJ, 1997, 'Anodic Coupling of Diphenylbenzo[k]fluoranthene: Mechanistic and Kinetic Studies Utilizing Cyclic Voltammetry and Electrogenerated Chemiluminescence', Journal of Organic Chemistry, 62, pp. 530 - 537, http://dx.doi.org/10.1021/jo961448e

Magnus P; Morris JC; Lynch V, 1997, 'Synthesis of 6,7-benz[c]acephenanthrylene and its photodimerization to a simple molecular tweezer', Synthesis, pp. 506 - 508, http://dx.doi.org/10.1055/s-1997-1233

Rogers DH; Morris JC; Roden FS; Frey B; King GR; Russkamp FW; Bell RA; Mander LN, 1996, 'The development of more efficient syntheses of polycyclic diterpenes through intramolecular cyclopropanation of aryl rings in diazomethyl ketones', Pure and Applied Chemistry, 68, pp. 515 - 522, http://dx.doi.org/10.1351/pac199668030515

Debad JD; Morris JC; Lynch V; Magnus P; Bard AJ, 1996, 'Dibenzotetraphenylperiflanthene:  Synthesis, Photophysical Properties, and Electrogenerated Chemiluminescence', Journal of the American Chemical Society, 118, pp. 2374 - 2379, http://dx.doi.org/10.1021/ja9537888

Conference Papers

Gao Y; Agrawal J; Amartey J; Hawtrey T; Morris J; Amoaku WMK; Bates D, 2024, 'The splicing of VEGF-A in monocytes from people with neovascular age related macular degeneration (nAMD) and diabetic retinopathy is altered by inhibition of SRPK1 and CLK', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, WA, Seattle, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), WA, Seattle, 05 May 2024 - 09 May 2024

Besidonne C; Benest A; Chisholm K; Morris J; Donaldson L; Woolard J; Bates D, 2024, 'Investigating the SRPK-1-VEGF-A Alternative Splicing Pathway AsaTherapeutic Target in Arthritis', in ARTHRITIS & RHEUMATOLOGY, WILEY, pp. 1849 - 1850

Levy J; David E; Hopkins T; Morris J; Tran ND; Farid H; Massari F; O'Connell WG; Vogel A; Gangi A; Sunenshine P; Dixon R; Von der Hoh N; Bagla S, 2021, 'Radiofrequency ablation for palliative treatment of osseous metastases results in rapid, significant, and durable improvements in pain relief and quality of life: Results from the OPuS One trial.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, ELECTR NETWORK, presented at Virtual Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), ELECTR NETWORK, 04 June 2021 - 08 June 2021, http://dx.doi.org/10.1200/JCO.2021.39.15_suppl.12086

Alalwany RH; Donaldson LF; Morgan K; Hawtrey TJ; Morris JC; Bates DO, 2020, 'CLK inhibition alters tau splicing and has a neuroprotective effect in vitro', in Alzheimer's & Dementia, Wiley, http://dx.doi.org/10.1002/alz.042805

Bates DO; Liddell S; Toop H; Stewart EA; Murphy A; Habgood A; Daubney J; Gutierrez-Caballero C; McKechnie K; Morris J; Batson J, 2019, 'Designing topical VEGF-A inhibitors with high retinal bioavailability using ex vivo permeability modelling', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, CANADA, Vancouver, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), CANADA, Vancouver, 28 April 2019 - 02 May 2019

Batson J; Toop H; Liddell S; Daubney J; Stewart EA; Habgood A; Murphy A; McKechnie K; Morris J; Bates DO, 2019, 'EXN407, a novel topical therapeutic candidate with high retinal bioavailability for the treatment of diabetic macular oedema, inhibits ocular neovascularisation', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, CANADA, Vancouver, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), CANADA, Vancouver, 28 April 2019 - 02 May 2019

Bhalla SR; Riu F; Marsden D; Allen C; Blackley Z; Batson J; Morris J; Bates D, 2019, 'Wnt5A Dependent Revascularisation After Ischemia Is SRPK1 Dependent', in JOURNAL OF VASCULAR RESEARCH, KARGER, NETHERLANDS, Maastricht, pp. 14 - 14, presented at 3rd Joint Meeting of the European-Society-for-Microcirculation (ESM) and the European-Vascular-Biology-Organization (EVBO), NETHERLANDS, Maastricht, 15 April 2019 - 18 April 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000463529300031&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Batson J; Toop H; Liddell S; Daubney J; Stewart E; McKechnie K; Morris J; Bates D, 2018, 'A novel approach to inhibit pro-angiogenic VEGF splicing in retinal vascular diseases with topical administration of small molecules optimised for retinal pharmacokinetics', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, HI, Honolulu, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), HI, Honolulu, 21 April 2018 - 03 May 2018

Karkenny AJ; Morris J; Hamm K; Maguire K; Toro J; Stone M; Fornari E; Schulz JF, 2018, 'Follow-up and Functional Outcomes of Pediatric Patients with Firearm Injuries to the Extremities', in PEDIATRICS, AMER ACAD PEDIATRICS, http://dx.doi.org/10.1542/peds.141.1_MeetingAbstract.621

Maiocchi S; Rees M; Morris J; Thomas S, 2017, 'Endothelial-targeted Nitroxides Inhibit MPO-mediated Endothelial Dysfunction', in FREE RADICAL BIOLOGY AND MEDICINE, ELSEVIER SCIENCE INC, MD, Baltimore, pp. 207 - 207, presented at 24th Annual Meeting of the Society-for-Redox-Biology-and-Medicine (SfRBM), MD, Baltimore, 29 November 2017 - 02 December 2017, http://dx.doi.org/10.1016/j.freeradbiomed.2017.10.328

Rigby C; Toop H; Al Mazi J; Morris J; Enjeti A; Verrills N; Dun M, 2017, 'Novel PP2A Inhibitory Protein in C-KIT Mutant Myeloid Progenitor Cells', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 7 - 8, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000413952600003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Batson J; Toop H; Stewart E; Daubney J; Morris J; Bates DO, 2017, 'Optimisation of potent SRPK1 inhibitors through modelling of permeability properties required for trans-scleral eye drop delivery', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, MD, Baltimore, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO) - Imaging in the Eye, MD, Baltimore, 06 May 2017 - 11 May 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000432170305102&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Bates DO; Toop H; Daubney J; Stewart E; Morris J; Batson J, 2017, 'Targeting SRPK1 with novel potent and selective small molecule inhibitors inhibits choroidal neovascularisation through modulating VEGF-A alternative splicing', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, MD, Baltimore, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO) - Imaging in the Eye, MD, Baltimore, 06 May 2017 - 11 May 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000432170301030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Batson J; Toop H; Rowlinson J; Allen CL; Brian G; Morris J; Bates DO, 2016, 'Development of topically administered retinal angiogenesis inhibitors with improved ocular permeability and therapeutic exposure in rabbit eyes', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, WA, Seattle, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), WA, Seattle, 01 May 2016 - 05 May 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000394174002193&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Zhang W; Morris J; Piperdi S; Guo Y; Ji T; Yang R; Roth M; Gill J; Geller DS; Gorlick R; Jones K; Zi X; Hoang BH, 2016, 'Flavokawain A and B from kava extract exhibits low toxicity and up-regulates tumor suppressor miRNAs in human osteosarcoma cells', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, LA, New Orleans, presented at 107th Annual Meeting of the American-Association-of-Cancer-Research (AACR), LA, New Orleans, 16 April 2016 - 20 April 2016, http://dx.doi.org/10.1158/1538-7445.AM2016-2182

Batson J; Troop H; Rowlinson J; Allen C; Babaei-Jadidi R; Zhang J; Wearmouth S; Knapp S; Morris J; Bates D, 2015, 'Development of SRPK1 inhibitors as novel anti-angiogenic therapeutics for exudative age-related macular degeneration (AMD)', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, CO, Denver, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), CO, Denver, 03 May 2015 - 07 May 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000362882206047&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Geller DS; Revskaya E; Khan M; Morris J; Gorlick R; Dadachova E, 2015, 'Targeted therapy of osteosarcoma with radiolabeled monoclonal antibody to an insulin-like growth factor-2 receptor', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-1798

Dun MD; Smith AM; Kahl RGS; Smith ND; Khanna A; Don AS; Toop HF; Morris JC; Verrills NM, 2013, 'Unraveling the mechanism of action: drugs that activate the tumor suppressor 2A.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-2038

Sukuru SCK; Crepin T; Morris JC; Grotli M; Danel F; Page MGP; Haertlein M; Cusack S; Kron MA; Kuhn LA, 2006, 'Contributions of conformational flexibility to Brugia malayi asparaginyl-tRNA synthetase specificity for inhibitors identified by structure-based screening', in ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, GA, Atlanta, presented at 231st National Meeting of the American-Chemical-Society, GA, Atlanta, 26 March 2006 - 30 March 2006, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000238125903697&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts

Collison A; Li J; De Siqueira AP; Lv X; Toop HD; Morris JC; Starkey MR; Hansbro PM; Zhang J; Mattes J, 2017, 'THE E3 UBIQUITIN LIGASE MID1 PROMOTES IDIOPATHIC PULMONARY FIBROSIS', in RESPIROLOGY, WILEY, Vol. 22, pp. 168 - 168

Maiocchi S; Dang L; Morris J; Thomas S; Rees M, 2015, 'Inhibition of Myeloperoxidase-Mediated Endothelial Dysfunction by Nitroxides', in FREE RADICAL BIOLOGY AND MEDICINE, ELSEVIER SCIENCE INC, GERMANY, Stuttgart, Vol. 86, pp. S28 - S29, presented at SFRR-E/SNFS Conference, GERMANY, Stuttgart, 02 September 2015 - 04 September 2015, http://dx.doi.org/10.1016/j.freeradbiomed.2015.07.103

Patents

Morris J; Szczepankiewicz B; Kremsky J; Toop H, 2023, Nicotinamide riboside analogs, pharmaceutical compositions, and uses thereof, Australia, Patent No. 2019214858

Morris J; Toop H; Kremsky J; Szczepankiewicz B, 2021, Nicotinamide riboside analogs, pharmaceutical compositions, and uses thereof, Patent No. US pat no. 11180521

Morris J; Bates D, 2019, Piperazine derivatives for treating disorders, Patent No. 6579714

Preprints

Bhalla SR; Wahid M; Amartey JO; Zawia A; Riu F; Gao Y; Agrawal J; Lynch AP; Machado MJC; Hawtrey T; Kikuchi R; Green KR; Teboul L; Allen C; Blackley Z; Rajaji K; Marsden D; Batson J; Harper SJ; Oltean S; Amoaku W; Benest AV; Morris JC; Braithwaite B; Bates DO, 2024, The splicing factor kinase SRPK1 is a therapeutic target for Peripheral Vascular Disease, http://dx.doi.org/10.1101/2024.04.17.589996

Diaz-Vegas A; Madsen S; Cooke KC; Carroll L; Khor JXY; Turner N; Lim XY; Astore MA; Morris J; Don A; Garfield A; Zarini S; Zemski Berry KA; Ryan A; Bergman BC; Brozinick JT; James DE; Burchfield JG, 2023, Mitochondrial electron transport chain, ceramide and Coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle., http://dx.doi.org/10.1101/2023.03.10.532020

Wohlwend M; Laurila P-P; Goeminne LJE; Lima T; Daskalaki I; Li X; von Alvensleben G; Crisol B; Mangione R; Gallart-Ayala H; Burri O; Butler S; Morris J; Turner N; Ivanisevic J; Auwerx J, 2023, Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction, http://dx.doi.org/10.1101/2023.08.05.552113

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