By Professor Laurent Billot

Journal articles

Zheng D; Arima H; Sato S; Gasparrini A; Heeley E; Delcourt C; Lo S; Huang Y; Wang J; Stapf C; Robinson T; Lavados P; Chalmers J; Anderson CS; Li Q; Neal B; Billot L; Woodward M, 2016, 'Low ambient temperature and intracerebral hemorrhage: The INTERACT2 study', PLoS ONE, 11, pp. e0149040, http://dx.doi.org/10.1371/journal.pone.0149040

Mathieson S; Billot L; Maher CG; McLachlan AJ; Latimer J; Koes BW; Hancock MJ; Harris I; Day RO; Pik J; Jan S; Lin CWC, 2016, 'PRECISE - pregabalin in addition to usual care: Statistical analysis plan', Trials, 17, pp. 53, http://dx.doi.org/10.1186/s13063-016-1174-y

Sato S; Delcourt C; Zhang S; Arima H; Heeley E; Zheng D; Al-Shahi Salman R; Stapf C; Tzourio C; Robinson T; Lindley RI; Chalmers J; Anderson CS, 2016, 'Determinants and prognostic significance of hematoma sedimentation levels in acute intracerebral hemorrhage', Cerebrovascular Diseases, 41, pp. 80 - 86, http://dx.doi.org/10.1159/000442532

Heeley E; Billot L; Anderson CS; Antic NA; Neal B; McEvoy RD, 2016, 'Statistical analysis plan for the Sleep Apnea cardioVascular Endpoints study: An international randomised controlled trial to determine whether continuous positive airways pressure treatment for obstructive sleep apnea in patients with CV disease prevents secondary cardiovascular events', International Journal of Stroke, 11, pp. 148 - 150, http://dx.doi.org/10.1177/1747493015607504

Sato S; Heeley E; Arima H; Delcourt C; Hirakawa Y; Pamidimukkala V; Li Z; Tao Q; Xu Y; Hennerici MG; Robinson T; Tzourio C; Lindley RI; Chalmers J; Anderson CS, 2015, 'Higher mortality in patients with right hemispheric intracerebral haemorrhage: INTERACT1 and 2', Journal of Neurology, Neurosurgery and Psychiatry, 86, pp. 1319 - 1323, http://dx.doi.org/10.1136/jnnp-2014-309870

Sato S; Arima H; Heeley E; Hirakawa Y; Delcourt C; Lindley RI; Robinson T; Huang Y; Morgenstern L; Stapf C; Wang J; Chalmers J; Anderson CS, 2015, 'Off-Hour admission and outcomes in patients with acute intracerebral hemorrhage in the INTERACT2 trial', Cerebrovascular Diseases, 40, pp. 114 - 120, http://dx.doi.org/10.1159/000434690

Saxena MK; Taylor C; Billot L; Bompoint S; Gowardman J; Roberts JA; Lipman J; Myburgh J, 2015, 'The effect of paracetamol on core body temperature in acute traumatic brain injury: A randomised, controlled clinical trial', PLoS ONE, 10, pp. e0144740, http://dx.doi.org/10.1371/journal.pone.0144740

Patel A; Cass A; Peiris D; Usherwood T; Brown A; Jan S; Neal B; Hillis GS; Rafter N; Tonkin A; Webster R; Billot L; Bompoint S; Burch C; Burke H; Hayman N; Molanus B; Reid CM; Shiel L; Togni S; Rodgers A, 2015, 'A pragmatic randomized trial of a polypill-based strategy to improve use of indicated preventive treatments in people at high cardiovascular disease risk', European Journal of Preventive Cardiology, 22, pp. 920 - 930, http://dx.doi.org/10.1177/2047487314530382

Finfer S; Chittock D; Li Y; Foster D; Dhingra V; Bellomo R; Cook D; Dodek P; Hebert P; Henderson W; Heyland D; Higgins A; McArthur C; Mitchell I; Myburgh J; Robinson B; Ronco J; Blair D; Norton R; Potter J; McDonald E; Peto R; Sandercock P; Sprung C; Young JD; Li Q; Bompoint S; Billot L; Crampton L; Darcy F; Jayne K; Kumarasinghe V; Little L; McEvoy S; MacMahon S; Pandey S; Ryan S; Shukla R; Vijayan B; Atherton S; Bell J; Hadfield L; Hourigan C; Newby L; Simmonds C; Buhr H; Eccleston M; McGuinness S; Parke R; Bates S; Goldsmith D; Mercer I; O’Sullivan K; Gazzard R; Hill D; Tauschke C; Ghelani D; Nand K; Reece G; Sara T; Elliott S; Ernest D; Hamilton A; Ashley R; Bailey A; Crowfoot E; Gissane J; Ranse J; Whiting J; Douglas K; Milliss D; Tan J; Wong H; Blythe D; Palermo A; Hardie M; Harrigan P; McFadyen B; Micallef S; Parr M; Boase A; Tai J; Williams A; Cole L; Seppelt I; Weisbrodt L; Whereat S; Flanagan A; Liang J; Bass F; Campbell M; Hammond N; Nicholson L; Shehabi Y; Foote J; Peake S; Williams P; Deans R; Fourie C; Lassig-Smith M, 2015, 'Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study', Intensive Care Medicine, 41, pp. 1037 - 1047, http://dx.doi.org/10.1007/s00134-015-3757-6

Muñoz-Venturelli P; Arima H; Lavados P; Brunser A; Peng B; Cui L; Song L; Billot L; Boaden E; Hackett ML; Heritier S; Jan S; Middleton S; Olavarría VV; Lim JY; Lindley RI; Heeley E; Robinson T; Pontes-Neto O; Natsagdorj L; Lin RT; Watkins C; Anderson CS; Woodward M, 2015, 'Head Position in Stroke Trial (HeadPoST) - sitting-up vs lying-flat positioning of patients with acute stroke: Study protocol for a cluster randomised controlled trial', Trials, 16, pp. 256, http://dx.doi.org/10.1186/s13063-015-0767-1

Nguyen Viet N; Yunus F; Nguyen Thi Phuong A; Dao Bich V; Damayanti T; Wiyono WH; Billot L; Jakes RW; Kwon N, 2015, 'The prevalence and patient characteristics of chronic obstructive pulmonary disease in non-smokers in Vietnam and Indonesia: An observational survey', Respirology, 20, pp. 602 - 611, http://dx.doi.org/10.1111/resp.12507

Priglinger M; Arima H; Anderson C; Krause M; Chalmers J; Huang Y; Wang JG; Bath P; Davis S; Kim J; Lindley R; Neal B; Morgenstern LB; MacMahon S; Woodward M; Butcher K; Chambers B; Donnan G; Levi C; Parsons MW; Dorsch N; Huang Y; Wang JG; Lu C; Chen S; Jiang JD; Liu Z; Zhang J; Kong L; Song Y; Wang Z; Wang W; Wu F; Yuan Y; Kim JS; Kim J; Simes J; Hankey G; Jamrozik K; Johnston S; Shunwei L; Skulina C; Peng B; Billot L; Li Q; Su S; Heritier S; Heeley E; Capper H; Chisholm J; Currie R; Fathers J; Hackett M; Homewood S; Jane K; Jones K; Leksuwat S; Mullane B; Pandey S; Patel A; Quilkey A; Scott J; Starzec G; Wadham A; Zeckendorf S; Han D; Ying S; Xu W; Zhang LJ; Huang Q; Li Y; Yan L; Kyung S, 2015, 'No relationship of lipid-lowering agents to hematoma growth: Pooled analysis of the intensive blood pressure reduction in acute cerebral hemorrhage trials studies', Stroke, 46, pp. 857 - 859, http://dx.doi.org/10.1161/STROKEAHA.114.007664

Li S; Wu Y; Du X; Li X; Patel A; Peterson ED; Turnbull F; Lo S; Billot L; Laba T; Gao R, 2015, 'Rational and design of a stepped-wedge cluster randomized trial evaluating quality improvement initiative for reducing cardiovascular events among patients with acute coronary syndromes in resource-constrained hospitals in China', American Heart Journal, 169, pp. 349 - 355, http://dx.doi.org/10.1016/j.ahj.2014.12.005

Saxena MK; Taylor C; Hammond N; Young P; Mysore J; Billot L; Myburgh A; Myburgh J, 2015, 'A multicentre audit of temperature patterns after traumatic brain injury', Critical Care and Resuscitation, 17, pp. 129 - 134

Arima H; Heeley E; Delcourt C; Hirakawa Y; Wang X; Woodward M; Robinson T; Stapf C; Parsons M; Lavados PM; Huang Y; Wang J; Chalmers J; Anderson CS, 2015, 'Optimal achieved blood pressure in acute intracerebral hemorrhage: INTERACT2', Neurology, 84, pp. 464 - 471, http://dx.doi.org/10.1212/WNL.0000000000001205

Zoungas S; Chalmers J; Neal B; Billot L; Li Q; Biostat M; Hirakawa Y; Arima H; Monaghan H; Joshi R; Colagiuri S; Cooper ME; Glasziou P; Grobbee D; Hamet P; Harrap S; Heller S; Lisheng L; Mancia G; Marre M; Matthews DR; Mogensen CE; Perkovic V; Poulter N; Rodgers A; Williams B; MacMahon S; Patel A; Woodward M, 2014, 'Follow-up of blood-pressure lowering and glucose control in type 2 diabetes', New England Journal of Medicine, 371, pp. 1392 - 1406, http://dx.doi.org/10.1056/NEJMoa1407963

Wang AY; Bellomo R; Ninomiya T; Lo S; Cass A; Jardine M; Gallagher M, 2014, 'Angiotensin-converting enzyme inhibitor usage and acute kidney injury: A secondary analysis of RENAL study outcomes', Nephrology, 19, pp. 617 - 622, http://dx.doi.org/10.1111/nep.12284

Hammond NE; Billot L; Finfer S; Myburgh J, 2014, 'Individual patient data comparative analysis of hydroxyethyl starch 130/0.4 v 4% albumin for fluid resuscitation in critically ill patients: Statistical analysis plan', Critical Care and Resuscitation, 16, pp. 206 - 213

Saxena MK; Hammond N; Myburgh J, 2014, 'Individual patient data meta-analysis of hydroxyethyl starch 130/0.4-0.42 versus crystalloid for fluid resuscitation in patients with severe sepsis: A statistical analysis plan', Critical Care and Resuscitation, 16, pp. 96 - 115, http://search.informit.com.au/documentSummary;res=IELHEA;dn=312745606203494

Du X; Gao R; Turnbull F; Wu Y; Rong Y; Lo S; Billot L; Hao Z; Ranasinghe I; Iedema R; Kong L; Hu D; Lin S; Shen W; Huang D; Yang Y; Ge J; Han Y; Lv S; Ma A; Gao W; Patel A, 2014, 'Hospital quality improvement initiative for patients with acute coronary syndromes in China a cluster randomized, controlled trial', Circulation: Cardiovascular Quality and Outcomes, 7, pp. 217 - 226, http://dx.doi.org/10.1161/CIRCOUTCOMES.113.000526

Jun M; Bellomo R; Cass A; Gallagher M; Lo S; Lee J, 2014, 'Timing of renal replacement therapy and patient outcomes in the randomized evaluation of normal versus augmented level of replacement therapy study', Critical Care Medicine, 42, pp. 1756 - 1765, http://dx.doi.org/10.1097/CCM.0000000000000343

Webster R; Patel A; Billot L; Cass A; Burch C; Neal B; Usherwood T; Thom S; Poulter N; Stanton A; Bots ML; Grobbee DE; Prabhakaran D; Reddy KS; Field J; Bullen C; Elley CR; Selak V; Rafter N; Wadham A; Berwanger O; Rodgers A, 2013, 'Prospective meta-analysis of trials comparing fixed dose combination based care with usual care in individuals at high cardiovascular risk: The SPACE Collaboration', International Journal of Cardiology, 170, pp. 30 - 35, http://dx.doi.org/10.1016/j.ijcard.2013.10.007

Hackett ML; Carter G; Crimmins D; Clarke T; Arblaster L; Billot L; Mysore J; Sturm J, 2013, 'ImProving Outcomes after STroke (POST): Results from the randomized clinical pilot trial', International Journal of Stroke, 8, pp. 707 - 710, http://dx.doi.org/10.1111/j.1747-4949.2012.00913.x

Zhang J; Liu G; Arima H; Li Y; Cheng G; Shiue I; Lv L; Wang H; Zhang C; Zhao J; Anderson CS, 2013, 'Incidence and risks of subarachnoid hemorrhage in China', Stroke, 44, pp. 2891 - 2893, http://dx.doi.org/10.1161/STROKEAHA.113.002599

Land MA; Christoforou A; Downs S; Webster J; Billot L; Li M; Peña-Rosas JP; Neal B, 2013, 'Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders', Cochrane Database of Systematic Reviews, 2013, http://dx.doi.org/10.1002/14651858.CD010734

Thom S; Poulter N; Field J; Patel A; Prabhakaran D; Stanton A; Grobbee DE; Bots ML; Reddy KS; Cidambi R; Bompoint S; Billot L; Rodgers A, 2013, 'Effects of a fixed-dose combination strategy on adherence and risk factors in patients with or at high risk of CVD: The UMPIRE randomized clinical trial', JAMA, 310, pp. 918 - 929, http://dx.doi.org/10.1001/jama.2013.277064

Williams CM; Maher CG; Latimer J; McLachlan AJ; Hancock MJ; Day RO; Billot L; Lin CWC, 2013, 'PACE - the first placebo controlled trial of paracetamol for acute low back pain: Statistical analysis plan', Trials, 14, http://dx.doi.org/10.1186/1745-6215-14-248

Finfer S; Billot L, 2013, 'Managing blood glucose in critically ill patients with or without diabetes', Critical Care, 17, http://dx.doi.org/10.1186/cc12591

Cooper DJ; Myburgh J; Heritier S; Finfer S; Bellomo R; Billot L; Murray L; Vallance S, 2013, 'Albumin resuscitation for traumatic brain injury: Is intracranial hypertension the cause of increased mortality?', Journal of Neurotrauma, 30, pp. 512 - 518, http://dx.doi.org/10.1089/neu.2012.2573

Gattas DJ; Dan A; Myburgh J; Billot L; Lo S; Finfer S, 2013, 'Fluid resuscitation with 6 % hydroxyethyl starch (130/0.4 and 130/0.42) in acutely ill patients: Systematic review of effects on mortality and treatment with renal replacement therapy', Intensive Care Medicine, 39, pp. 558 - 568, http://dx.doi.org/10.1007/s00134-013-2840-0

Bellomo R; Lipcsey M; Calzavacca P; Haase M; Haase-Fielitz A; Licari E; Tee A; Cole L; Cass A; Finfer S; Gallagher M; Lee J; Lo S; McArthur C; McGuinness S; Myburgh J; Scheinkestel C, 2013, 'Early acid-base and blood pressure effects of continuous renal replacement therapy intensity in patients with metabolic acidosis', Intensive Care Medicine, 39, pp. 429 - 436, http://dx.doi.org/10.1007/s00134-012-2800-0

Guidet B, 2013, 'Hydroxyethyl Starch or Saline in Intensive Care', NEW ENGLAND JOURNAL OF MEDICINE, 368, pp. 774 - 774, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000315095800018&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Raghunathan K; Shaw A, 2013, 'Hydroxyethyl Starch or Saline in Intensive Care', NEW ENGLAND JOURNAL OF MEDICINE, 368, pp. 774 - 775, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000315095800019&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Myburgh JA; Finfer S; Billot L, 2013, 'The authors reply', New England Journal of Medicine, 368, pp. 775, http://dx.doi.org/10.1056/NEJMc1215977

Myburgh JA; Finfer S; Billot L; CHEST Investigators , 2013, 'Hydroxyethyl starch or saline in intensive care.', The New England journal of medicine, 368, pp. 775, http://dx.doi.org/10.1056/NEJMc1215531

Anderson CS; Heeley E; Huang Y; Wang J; Stapf C; Delcourt C; Lindley R; Robinson T; Lavados P; Neal B; Hata J; Arima H; Parsons M; Li Y; Wang J; Heritier S; Li Q; Woodward M; Simes RJ; Davis SM; Chalmers J, 2013, 'Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage', New England Journal of Medicine, 368, pp. 2355 - 2365, http://dx.doi.org/10.1056/NEJMoa1214609

Harris IA; Day RO, 2013, 'PRECISE - pregabalin in addition to usual care for sciatica: study protocol for a randomised controlled trial', Trials, 14, pp. 213, http://dx.doi.org/10.1186/1745-6215-14-213

Bellomo R; Cass A; Cole L; Finfer SR; Gallagher M; Lee J; Lo S; Mcarthur C; Mcguiness S; Norton R; Myburgh J; Scheinkestel C; Su S, 2012, 'An observational study fluid balance and patient outcomes in the randomized evaluation of normal vs. augmented level of replacement therapy trial', Critical Care Medicine, 40, pp. 1753 - 1760, http://dx.doi.org/10.1097/CCM.0b013e318246b9c6

Gattas DJ; Dan A; Myburgh J; Billot L; Lo S; Finfer S, 2012, 'Fluid Resuscitation With 6% Hydroxyethyl Starch (130/0.4) in Acutely Ill Patients', Survey of Anesthesiology, 56, pp. 216 - 217, http://dx.doi.org/10.1097/01.sa.0000418862.49400.d1

Gattas D; Dan A; Myburgh J; Billot L; Lo S; Finfer SR; Collaborators , 2012, 'Fluid resuscitation with 6% hydroxyethyl starch (130/0.4) in acutely ill patients: an updated systematic review and meta-analysis.', Anesthesia and Analgesia, 114, pp. 159 - 169, http://dx.doi.org/10.1213/ANE.0b013e318236b4d6

Myburgh J; Finfer SR; Bellomo R; Billot L; Cass A; Parr MJ; et A, 2012, 'Hydroxyethyl starch or saline for fluid resuscitation in intensive care', New England Journal of Medicine, 367, pp. 1901 - 1911, http://dx.doi.org/10.1056/NEJMoa1209759

Finfer SR; Mcevoy S; Bellomo R; McArthur C; Myburgh J; Norton R; etal , 2011, 'Impact of albumin compared to saline on organ function and mortality of patients with severe sepsis.', Intensive Care Medicine, 37, pp. 86 - 96, http://dx.doi.org/10.1007/s00134-010-2039-6

Zoungas S; Patel A; Chalmers J; De Galan BE; Li Q; Billot L; Woodward M; Ninomiya T; Neal B; MacMahon S; Grobbee DE; Kengne AP; Marre M; Heller S, 2010, 'Severe hypoglycemia and risks of vascular events and death', New England Journal of Medicine, 363, pp. 1410 - 1418, http://dx.doi.org/10.1056/NEJMoa1003795

Zoungas S; Chalmers J; Kengne AP; Pillai A; Billot L; de Galan B; Marre M; Neal B; Harrap S; Poulter N; Patel A, 2010, 'The efficacy of lowering glycated haemoglobin with a gliclazide modified release-based intensive glucose lowering regimen in the ADVANCE trial', Diabetes Research and Clinical Practice, 89, pp. 126 - 133, http://dx.doi.org/10.1016/j.diabres.2010.05.012

Finfer SR; Liu B; Taylor C; Bellomo R; Billot L; Cook DL; Du B; McArthur C; Myburgh J, 2010, 'Resuscitation fluid use in critically ill adults: An international cross-sectional study in 391 intensive care units', Netherland Journal of Critical Care, 14, pp. R185, http://dx.doi.org/10.1186/cc9293

Bellomo R; Cass A; Cole L; Finfer S; Gallagher M; Lo S; McArthur C; McGuinness S; Myburgh J; Norton R; Scheinkestel C; Su S, 2009, 'Intensity of continuous renal-replacement therapy in critically ill patients', New England Journal of Medicine, 361, pp. 1627 - 1638, http://dx.doi.org/10.1056/NEJMoa0902413

Finfer S; Bellomo R; Blair D; Su SYS; Foster D; Dhingra V; Cook D; Dodek P; Henderson WR; Hébert PC; Heyland DK; McArthur C; McDonald E; Mitchell I; Myburgh JA; Nor-ton R; Potte J; Robinson BG, 2009, 'Intensive versus conventional glucose control in critically Ill patients', New England Journal of Medicine, 360, pp. 1283 - 1297, http://dx.doi.org/10.1056/NEJMoa0810625

Bordom JH; Billot L; Gueguen R; Deschamps JP, 2008, 'New growth charts for Libyan preschool children', Eastern Mediterranean Health Journal, 14, pp. 1400 - 1412

Patel A; MacMahon S; Chalmers J; Neal B; Billot L; Woodward M; Marre M; Cooper M; Glasziou P; Grobbee D; Hamet P; Harrap S; Heller S; Liu L; Mancia G; Mogensen CE; Pan C; Poulter N; Rodgers A; Williams B; Bompoint S; De Galan BE; Joshi R; Travert F, 2008, 'Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes', New England Journal of Medicine, 358, pp. 2560 - 2572, http://dx.doi.org/10.1056/NEJMoa0802987

Anderson CS; Huang Y; Wang JG; Arima H; Neal B; Peng B; Heeley E; Skulina C; Parsons MW; Kim JS; Tao QL; Li YC; Jiang JD; Tai LW; Zhang JL; Xu E; Cheng Y; Heritier S; Morgenstern LB; Chalmers J, 2008, 'Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial', The Lancet Neurology, 7, pp. 391 - 399, http://dx.doi.org/10.1016/S1474-4422(08)70069-3

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