By Professor Paul De Souza

Journal articles

Rathkopf DE; Smith MR; De Bono JS; Logothetis C; Shore ND; De Souza PL; Fizazi K; Mulders P; Mainwaring PN; Hainsworth JD; Beer TM; North SA; Fradet Y; Griffin TW; Park YC; Kheoh TS; Small EJ; Scher HI; Molina A; Ryan CJ, 2013, 'Updated interim analysis (IA) of COU-AA-302, a randomized phase III study of abiraterone acetate (AA) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy.', Journal of Clinical Oncology, 31, pp. 5 - 5, http://dx.doi.org/10.1200/jco.2013.31.6_suppl.5

Paz-Ares L; Bálint B; De Boer RH; Van Meerbeeck JP; Wierzbicki R; De Souza P; Galimi F; Haddad V; Sabin T; Hei YJ; Pan Y; Cottrell S; Hsu CP; Ramlau R, 2013, 'A randomized phase 2 study of paclitaxel and carboplatin with or without conatumumab for first-line treatment of advanced non-small-cell lung cancer', Journal of Thoracic Oncology, 8, pp. 329 - 337, http://dx.doi.org/10.1097/JTO.0b013e31827ce554

Lim S; de Souza P, 2013, 'Imatinib in neurofibromatosis type 2', BMJ case reports, 2013, http://dx.doi.org/10.1136/bcr-2013-010274

Motzer RJ; Hutson TE; Cella D; Reeves J; Hawkins R; Guo J; Nathan P; Staehler M; Souza P; Merchan JR; Boleti E; Fife K; Jin J; Jones R; Uemura H; De Giorgi U; Harmenberg U; Wang J; Sternberg CN; Deen K; McCann L; Hackshaw MD; Crescenzo R; Pandite LN; Choueiri TK, 2013, 'Pazopanib versus sunitinib in metastatic renal-cell carcinoma', New England Journal of Medicine, 369, pp. 722 - 731, http://dx.doi.org/10.1056/NEJMoa1303989

Kim M; Li M; Intong LRA; Tran K; Melbourne W; Marucci D; Bucci J; De Souza P; Mallesara G; Murrell DF, 2013, 'Use of cetuximab as an adjuvant agent to radiotherapy and surgery in recessive dystrophic epidermolysis bullosa with squamous cell carcinoma', British Journal of Dermatology, 169, pp. 208 - 210, http://dx.doi.org/10.1111/bjd.12272

Saad F; Shore ND; Van Poppel H; Rathkopf D; Smith MR; de Bono JS; Logothetis C; de Souza P; Fizazi K; Mulders PFA; Mainwaring P; Hainsworth JD; Beer TM; North S; Fradet Y; Griffin T; Kheoh T; Small EJ; Scher HI; Molina A; Ryan CJ, 2013, '713 ABIRATERONE ACETATE IN METASTATIC CASTRATION-RESISTANT PROSTATE CANCER PATIENTS WITHOUT PRIOR CHEMOTHERAPY - INTERIM ANALYSIS OF THE COU-AA-302 PHASE 3 TRIAL', Journal of Urology, 189, http://dx.doi.org/10.1016/j.juro.2013.02.272

Van Poppel H; Rathkopf D; Smith MR; De Bono JS; Logothetis CJ; Shore ND; De Souza P; Fizazi K; Mulders PFA; Mainwaring P; Hainsworth JD; Beer TM; North S; Fradet Y; Griffin T; Park YC; Kheoh T; Small EJ; Scher HI; Molina A; Ryan CJ, 2013, '97 Updated interim analysis (IA): Results of randomized phase 3 study COU-AA-302 of abiraterone acetate (AA) in metastatic castration-resistant prostate cancer (mCRPC) patients (pts) without prior chemotherapy', European Urology Supplements, 12, pp. e97 - e98, http://dx.doi.org/10.1016/s1569-9056(13)60589-8

Ryan C; Smith M; de Bono J; Molina A; Logothetis D; De Souza P; et A, 2013, 'Abiraterone in metastatic prostate cancer without previous chemotherapy', New England Journal of Medicine, 368, pp. 138 - 148, http://dx.doi.org/10.1056/NEJMoa1209096

Suttle A; De Souza P; Arumugham T, 2013, 'Bayesian methods for pharmacokinetic/pharmacodynamic modeling of pazopanib-induced increases in blood pressure and transaminases', Journal of Clinical Pharmacology, 53, pp. 377 - 384, http://dx.doi.org/10.1002/jcph.16

Yee GPC; De Souza P; Khachigian LM, 2013, 'Current and potential treatments for cervical cancer', Current Cancer Drug Targets, 13, pp. 205 - 220, http://dx.doi.org/10.2174/1568009611313020009

Scarano W; Duong HTT; Lu HX; De Souza PL; Stenzel MH, 2013, 'Folate Conjugation to Polymeric Micelles via Boronic Acid Ester to Deliver Platinum Drugs to Ovarian Cancer Cell Lines', Biomacromolecules, 14, pp. 962 - 975, http://dx.doi.org/10.1021/bm400121q

Lim S; Descallar J; Sayaloune P; Delaney G; Papadatos G; de Souza P, 2012, 'CORRELATION OF GRADE & HORMONE-RECEPTOR STATUS WITH STAGE IN NODE-POSITIVE, NON-METASTATIC BREAST CANCER', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 8, pp. 335 - 335, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310544400357&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Kim M; Li M; Intong LRA; Tran K; Melbourne W; Marucci D; Inder S; de Souza P; Mallesara G; Murrell DF, 2012, 'USE OF CETUXIMAB AS AN ADJUVANT AGENT TO RADIOTHERAPY AND SURGERY IN RECESSIVE DYSTROPHIC EPIDERMOLYSIS BULLOSA WITH SQUAMOUS CELL CARCINOMA', WOUND REPAIR AND REGENERATION, 20, pp. A60 - A60, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308945000030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Thientosapol E; Nelson M; Descallar J; de Souza P, 2012, 'AN EXPLORATORY ANALYSIS OF THE LONGITUDINAL RELATIONSHIPS BETWEEN PROSTATE SPECIFIC ANTIGEN AND THE INFLAMMATORY MARKERS C-REACTIVE PROTEIN AND ERYTHROCYTE SEDIMENTATION RATE', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 8, pp. 58 - 58, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000306960100049&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hovey E; de Souza P; Marx G; Parente P; Rapke T; Hill A; Bonaventura A; Michele A; Kraft P; Lloyd A, 2012, 'PHASE III, RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF MODAFINIL FOR FATIGUE IN PATIENTS TREATED WITH DOCETAXEL-BASED CHEMOTHERAPY', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 8, pp. 44 - 44, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000306960100015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lim S; Descallar J; Sayaloune P; Delaney G; Papadatos G; de Souza P, 2012, 'TUMOUR:NODE RATIO IN NODE-POSITIVE, NON-METASTATIC BREAST CANCER', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 8, pp. 37 - 37, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000306960100006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lee CK; Marschner IC; Simes RJ; Voysey M; Egleston B; Hudes G; De Souza P, 2012, 'Increase in cholesterol predicts survival advantage in renal cell carcinoma patients treated with temsirolimus', Clinical Cancer Research, 18, pp. 3188 - 3196, http://dx.doi.org/10.1158/1078-0432.CCR-11-3137

Ryan CJ; Smith MR; De Bono JS; Molina A; Logothetis C; De Souza PL; Fizazi K; Mainwaring PN; Piulats Rodriguez JM; Ng S; Carles J; Mulders P; Kheoh TS; Griffin TW; Small EJ; Scher HI; Rathkopf DE, 2012, 'Interim analysis (IA) results of COU-AA-302, a randomized, phase III study of abiraterone acetate in chemotherapy-naive patients (pts) with metastatic castration-resistant prostate cancer (mCRPC).', Journal of Clinical Oncology, 30, pp. LBA4518 - LBA4518, http://dx.doi.org/10.1200/jco.2012.30.15_suppl.lba4518

Hovey EJ; De Souza PL; Marx GM; Rapke T; Parente P; Hill A; Bonaventura A; Michele A; Craft PS; Abdi EA; Lloyd AR, 2012, 'Modafinil for fatigue associated with docetaxel-based chemotherapy: A randomized controlled trial.', Journal of Clinical Oncology, 30, pp. e15152 - e15152, http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e15152

Lemech CR; Fontela A; Arkenau H-T; Chin MTM; Li S; Liauw WS; Thomas D; De Souza PL, 2012, 'Phase I study of everolimus in combination with fluvastatin and zoledronic acid in patients with solid tumours.', Journal of Clinical Oncology, 30, pp. e13585 - e13585, http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e13585

Hovey EJ; De Souza PL; Marx GM; Parente P; Rapke T; Hill A; Bonaventura A; Michele A; Craft PS; Abdi EA; Lloyd AR, 2012, 'Modafinil for fatigue associated with docetaxel-based chemotherapy: A randomized controlled trial', JOURNAL OF CLINICAL ONCOLOGY, 30, http://dx.doi.org/10.1200/jco.2012.30.5_suppl.211

Hovey EJ; De Souza PL; Marx GM; Parente P; Rapke T; Hill A; Bonaventura A; Michele A; Craft PS; Abdi EA; Lloyd AR, 2012, 'Modafinil for fatigue associated with docetaxel-based chemotherapy: A randomized controlled trial.', J Clin Oncol, 30, pp. 211, http://www.ncbi.nlm.nih.gov/pubmed/27967925

Coupe N; Harrison M; Chua W; De Souza P, 2012, 'Biomarkers for tyrosine kinase inhibitors in renal cell cancer', Translational Andrology and Urology, 1, pp. 216 - 222, http://dx.doi.org/10.3978/j.issn.2223-4683.2012.10.01

Huynh VT; Binauld SDM; De souza P; Stenzel MH, 2012, 'Acid Degradable Cross-Linked Micelles for the Delivery of Cisplatin: A Comparison with Nondegradable Cross-Linker', Chemistry of materials, 24, pp. 3197 - 3211, http://dx.doi.org/10.1021/cm301556b

Ryan CJ; Morris M; Molina A; Piulats JR; De Souza P; Li J; Kheoh T; de Bono JS; Larson S; Griffin T; Matheny S; Naini V; Scher HI; Small E, 2012, 'Association of Radiographic Progression-Free Survival (RPFS) Adapted from Prostate Cancer Working Group 2 (PCWG2) Consensus Criteria (APCWG2) with Overall Survival (OS) in Patients (PTS) with Metastatic Castration-Resistant Prostate Cancer (MCRPC): Results from COU-AA-302', Annals of Oncology, 23, pp. ix294 - ix295, http://dx.doi.org/10.1016/s0923-7534(20)33459-1

Huynh VT; Quek JY; De Souza P; Stenzel MH, 2012, 'Block copolymer micelles with pendant bifunctional chelator for platinum drugs: Effect of spacer length on the viability of tumor cells', Biomacromolecules, 13, pp. 1010 - 1023, http://dx.doi.org/10.1021/bm2017299

Goldstein D; Bennett BK; Webber K; Boyle F; De Souza P; Wilcken NRC; Scott E; Toppler R; Murie P; O''Malley L; Mccourt J; Friedlander M; Hickie IB; Lloyd AR, 2012, 'Cancer-related fatigue in women with breast cancer: outcomes of a 5 year prospective cohort study.', Journal of Clinical Oncology, 30, pp. 1805 - 1812, http://dx.doi.org/10.1200/JCO.2011.34.6148

Xu C; Xue Z; Bing NX; King K; De Souza P; et A, 2012, 'Concomitant use of pazopanib and simvastatin increases the risk of transaminase elevations in patients with cancer', Annals of Oncology, 23 Sep 2012, pp. 2470 - 2471, http://dx.doi.org/10.1093/annonc/mds249

Boyer M; Horwood K; Pavlakis N; De Souza P; Millward MJ; Stein B; Johnston M; Abell F; Rischin D, 2012, 'Efficacy of erlotinib in patients with advanced Non-small-cell Lung Cancer (NSCLC): Analysis of the Australian subpopulation of the TRUST study.', Asia-Pacific Journal of Clinical Oncology, 8, pp. 248 - 254, http://dx.doi.org/10.1111/j.1743-7563.2012.01540.x

Lim SH; Descallar J; Sayaloune P; Papadatos G; De Souza P; Delaney G, 2012, 'Outcomes of Ethnic Minority Groups With Node-Positive, Non-Metastatic Breast Cancer in a Tertiary Referral Centre in Sydney', Annals of Oncology, 23, pp. ix100 - ix100, http://dx.doi.org/10.1016/s0923-7534(20)32823-4

Cameron BA; Bennett B; Li H; Boyle F; deSouza P; Wilcken N; Friedlander M; Goldstein D; Lloyd AR, 2012, 'Post-cancer fatigue is not associated with immune activation or altered cytokine production', Annals of Oncology, 23, pp. 2890 - 2895, http://dx.doi.org/10.1093/annonc/mds108

Motzer R; Hutson TE; Reeves J; Hawkins R; Guo J; Nathan P; Staehler M; de Souza P; Merchan JR; Fife K; Jin J; Jones R; Uemura H; De Giorgi U; Harmenberg U; Wang J; Cella D; McCann L; Deen K; Choueiri TK, 2012, 'Randomized, Open-Label, Phase III Trial Of Pazopanib Versus Sunitinib In First-Line Treatment Of Patients With Metastatic Renal Cell Carcinoma (MRCC): Results of the Comparz Trial', Annals of Oncology, 23, pp. ixe13 - ixe13, http://dx.doi.org/10.1016/s0923-7534(20)34325-8

Won CM; Gurney H; Marx G; De Souza P; Patel MI, 2011, 'PRIMARY TREATMENT OF THE PROSTATE IMPROVES LOCAL PALLIATION IN MEN WHO ULTIMATELY DEVELOP CASTRATE RESISTANT PROSTATE CANCER.', JOURNAL OF ENDOUROLOGY, 25, pp. A256 - A257, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000296792201146&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Glass SM; Huang L; King K; Ragone LJ; Ball HA; De Souza PL; Wagstaff J; Spraggs CF; Mooser VE; Pandite LN; Xu C, 2011, 'Genetic evaluation of fatigue in pazopanib-treated patients (pts) with advanced renal cell carcinoma (RCC).', J Clin Oncol, 29, pp. e15072, http://www.ncbi.nlm.nih.gov/pubmed/28020421

De Souza P; Saad F, 2011, 'Bone health in prostate cancer', Expert Review of Endocrinology and Metabolism, 6, pp. 317 - 321, http://dx.doi.org/10.1586/eem.11.4

Li S; de Souza P, 2011, 'Ras isoprenylation and pAkt inhibition by zoledronic acid and fluvastatin enhances paclitaxel activity in T24 bladder cancer cells', Cancers, 3, pp. 662 - 674, http://dx.doi.org/10.3390/cancers3010662

Manners S; Galettis P; De Souza PL, 2011, 'Conditions causing gemcitabine crystallization', Journal of Oncology Pharmacy Practice, 17, pp. 395 - 399, http://dx.doi.org/10.1177/1078155210385033

Gu W; Gaborieau M; Huynh VT; De Souza PL; Stenzel MH, 2011, 'Functionalization of microspheres with malonates using Michael Addition as a pathway to create a drug delivery system for platinum drugs for the treatment of liver cancer', Polymer, 52, pp. 5993 - 6002, http://dx.doi.org/10.1016/j.polymer.2011.10.054

Xu C; Bing NX; Ball HA; Rajagopalan D; Sternberg CN; Hutson T; De Souza PL; Xue ZG; McCann L; King KS; Ragone LJ; Whittaker JC; Spraggs C; Cardon LR; Mooser VE; Pandite LN, 2011, 'Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes', Journal of Clinical Oncology, 29, pp. 2557 - 2564, http://dx.doi.org/10.1200/JCO.2010.32.9110

Howes J; De Souza PL; Weston L; Huang LJ; Howes LG, 2011, 'Pharmacokinetics of phenoxodiol, a novel isoflavone, following intravenous administration to patients with advanced cancer', BMC Clinical Pharmacology, 11, pp. 1 - 8, http://dx.doi.org/10.1186/1472-6904-11-1

Huynh VT; De Souza PL; Stenzel MH, 2011, 'Polymeric micelles with pendant dicarboxylato chelating ligands prepared via a michael addition for cis -platinum drug delivery', Macromolecules, 44, pp. 7888 - 7900, http://dx.doi.org/10.1021/ma2016503

De Souza PL; North S; Bolger GB; Spiridonidis H; Lim R; Khoo KS; Phillips J; Fujimori M, 2010, 'A phase II trial of weekly i.v. KW-2170 in advanced castrate-resistant prostate cancer', Asia-Pacific Journal of Clinical Oncology, 6, pp. 292 - 297, http://dx.doi.org/10.1111/j.1743-7563.2010.01328.x

Hutson TE; Davis ID; MacHiels JP; De Souza PL; Rottey S; Hong BF; Epstein RJ; Baker KL; McCann L; Crofts T; Pandite L; Figlin RA, 2010, 'Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma', Journal of Urology, 184, pp. 1303, http://dx.doi.org/10.1016/j.juro.2010.06.075

Webber K; Goldstein D; Bennett BK; Boyle FM; De Souza PL; Wilcken N; Friedlander M; Lloyd AR, 2010, 'Influence of fatigue after breast cancer adjuvant theraphy on health care utilization and percieved needs', JOURNAL OF CLINICAL ONCOLOGY, 28, http://dx.doi.org/10.1200/jco.2010.28.15_suppl.9047

De Souza PL; Mellado B; Pfister C; Rosenthal M; Castellano DE; Weber D; Ferrara S; Shaik N; Tan E; Patterson SA, 2010, 'Randomized phase II trial of patupilone plus prednisone versus docetaxel plus prednisone in patients with chemotherapy-naive, metastatic, castrate-resistant prostate cancer(CRPC)', JOURNAL OF CLINICAL ONCOLOGY, 28, http://dx.doi.org/10.1200/jco.2010.28.15_suppl.4553

Hutson TE; Davis ID; Machiels JPH; De Souza PL; Rottey S; Hong BF; Epstein RJ; Baker KL; McCann L; Crofts T; Pandite L; Figlin RA, 2010, 'Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma', Journal of Clinical Oncology, 28, pp. 475 - 480, http://dx.doi.org/10.1200/JCO.2008.21.6994

De Souza PL; Russell PJ; Kearsley J; Howes LG, 2010, 'Clinical pharmacology of isoflavones and its relevance for potential prevention of prostate cancer.', Nutrition Reviews, 68, pp. 542 - 555, http://dx.doi.org/10.1111/j.1753-4887.2010.00314.x

Duong HTT; Huynh TV; De Souza PL; Stenzel M, 2010, 'Core-Crosslinked Micelles synthesized by Clicking Bifunctional Pt(IV) Anticancer Drugs to Isocyanates', Biomacromolecules, 11, pp. 2290 - 2299, http://dx.doi.org/10.1021/bm100396s

Scott KF; Sajinovic M; Hein J; Nixdorf S; Galettis P; Liauw WS; De Souza PL; Dong Q; Graham GG; Russell PJ, 2010, 'Emerging roles for phospholipase A2 enzymes in cancer', Biochimie, 92, pp. 601 - 610

Khasraw M; Pavlakis N; Mccowatt S; Underhill C; Begbie S; De Souza PL; Boyce A; Parnis F; Lim V; Harvie R; Marx G, 2010, 'Multicentre phase I/II study of PI-88, a heparanase inhibitor in combination with docetaxel in patients with metastatic castrate-resistant prostate cancer', Annals of Oncology, 21, pp. 1302 - 1307, http://dx.doi.org/10.1093/annonc/mdp524

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