By Professor Richard Bryan Lock

Conference Papers

Lock RB; Evans K; Jones CD; El-Zein N; Erickson SW; Beaussant-Cohen S; Kelley EL; Teicher BA; Smith MA, 2019, 'Abstract C004: The CXCR4 inhibitor X4-136 enhances the in vivo efficacy of established drugs against preclinical models of aggressive pediatric acute lymphoblastic leukemia', in Molecular Cancer Therapeutics, American Association for Cancer Research (AACR), pp. c004 - c004, http://dx.doi.org/10.1158/1535-7163.targ-19-c004

Fleuren E; Xie J; Barahona P; Sherstyuk A; Batey D; Jin Yi L; Lau L; Khuong Quang DA; Failes T; Chow S-O; Mayoh C; Wong M; Kumar A; ZERO OT; ZERO PDTT; ZERO SMT; Thomas D; Trahair T; Haber M; Mould E; Lock R; Ziegler D; Tyrrell V; Cowley M; Ekert P, 2019, 'Personalised medicine for high-risk paediatric and AYA sarcoma patients', Tokyo, Japan, presented at Connective Tissue Oncology Society (CTOS) Annual Meeting, Tokyo, Japan, 13 November 2019, https://www.ctos.org/Portals/0/PDF/2019%20CTOS%20Final%20Program.pdf

Li J; Troche C; Zhang JH; Shrimp J; Roth JS; Jing D; Swaroop A; Kulis M; Oyer J; Will C; Dupere-Richer D; Riva A; Pipe C; Sobn A; Norton S; Bennett RL; Shen M; Hall MD; Lock RB; Licht JD, 2019, 'A Gain of Function Mutation in the NSD2 Histone Methyltransferase Drives Glucocorticoid Resistance Via Blocking Receptor Auto-Induction and BIM/Bmf Expression in ALL', in Blood, American Society of Hematology, pp. 3758, http://dx.doi.org/10.1182/blood-2019-126910

Lock RB; Evans K; Jones CD; El-Zein N; Bendak K; Toscan CE; Mayoh C; Erickson SW; Teicher BA; Smith MA, 2019, 'Pediatric Preclinical Testing Consortium Evaluation of the Novel Anti-Microtubule Drug E7130 in Xenograft Models of Early T-Cell Precursor Acute Lymphoblastic Leukemia', in Blood, American Society of Hematology, pp. 3875, http://dx.doi.org/10.1182/blood-2019-123867

Fleuren E; Lau L; Barahona P; Sherstyuk A; Mayoh C; Khuong Quang DA; Wong M; Xie J; Batey D; Grebert-Wade D; Strong P; Lim JL; Chow S-O; Kumar A; Failes T; Arndt G; Mould E; Haber M; Lock R; Trahair T; Marshall G; Ziegler D; Tyrrell V; Cowley M; Ekert P, 2019, 'Precision medicine for high-risk paediatric and AYA sarcomas', Sydney, presented at Kids Cancer Alliance - Annual Meeting, Sydney, 31 October 2019, https://kca.org.au/wp-content/uploads/2019/11/2019-ECR-and-Student-Event-Program.pdf

Teicher BA; Lock RB; Evans K; Houghton PJ; Kurmasheva RT; Gorlicki R; Erickson S; Wishka D; Morris J; Difilippantonio M; Collins JE; Smith MA; Doroshow JH, 2019, 'Abstract 3839: Comparison of thio-deoxy-cytidine (TdCyd) and aza-thio-deoxy-cytidine (Aza-TdCyd) in solid and liquid tumor cell lines and PPTC pediatric xenografts', in Cancer Research, American Association for Cancer Research (AACR), pp. 3839 - 3839, http://dx.doi.org/10.1158/1538-7445.am2019-3839

Earley E; Gorlick R; Houghton PJ; Maris JM; Li X-N; Lock RB; Teicher B; Smith MA; Erickson SW, 2019, 'Abstract LB-321: Re-evaluating sample sizes in preclinical testing of patient-derived xenografts', in Cancer Research, American Association for Cancer Research (AACR), pp. lb-321-lb-321, http://dx.doi.org/10.1158/1538-7445.am2019-lb-321

Earley E; Gorlick R; Houghton PJ; Maris JM; Li X-N; Lock RB; Teicher B; Smith MA; Erickson SW, 2019, 'Abstract LB-321: Re-evaluating sample sizes in preclinical testing of patient-derived xenografts', American Association for Cancer Research (AACR), pp. lb-321-lb-321, presented at Tumor Biology, http://dx.doi.org/10.1158/1538-7445.sabcs18-lb-321

Lock RB; Evans K; Pritchard T; Toscan C; Mayoh C; Teicher B; Kurmasheva RT; Houghton PJ; Smith M, 2018, 'A Single Mouse Trial Platform for Evaluation of Novel Agents in Acute Lymphoblastic Leukemia By the Pediatric Preclinical Testing Consortium', in Blood, American Society of Hematology, pp. 4010, http://dx.doi.org/10.1182/blood-2018-99-113207

Jing D; Huang Y; Liu X; Sia K; Poulos RC; Span M; Zhang C; Mi J; Wong JW; Beck D; Pimanda JE; Lock RB, 2018, 'Abstract 3173: Lymphocyte-specific chromatin accessibility predetermines glucocorticoid resistance in acute lymphoblastic leukemia', in Cancer Research, American Association for Cancer Research (AACR), pp. 3173 - 3173, http://dx.doi.org/10.1158/1538-7445.am2018-3173

Lock RB; Evans K; Pritchard T; Erickson SW; Guo Y; Claremon DA; McGeehan GM; Teicher BA; Smith MA, 2018, 'Abstract 3187: Pediatric Preclinical Testing Consortium evaluation of the menin inhibitor, VTP-50469, against xenograft models of MLL-rearranged infant acute lymphoblastic leukemia', in Cancer Research, American Association for Cancer Research (AACR), pp. 3187 - 3187, http://dx.doi.org/10.1158/1538-7445.am2018-3187

Teicher BA; Lock RB; Collins JM; Gorlick R; Kolb EA; Houghton PJ; Kurmasheva RT; Li X-N; Erickson SW; Guo Y; Evans K; Qi L; Smith MA, 2018, 'Abstract LB-B12: Pediatric Preclinical Testing Consortium evaluation of 4’-thio-2’-deoxycytidine (TdCyd) and 5-aza-4’-thio-2’-deoxycytidine (Aza-TdCyd)', in Molecular Cancer Therapeutics, American Association for Cancer Research (AACR), pp. lb-b12-lb-b12, http://dx.doi.org/10.1158/1535-7163.targ-17-lb-b12

Krytska K; Evans K; Pritchard T; Tsang M; Yung R; Mosse YP; Erickson SW; Guo Y; Baloglu E; Landesman Y; Jensen KA; Senapedis W; Teicher BA; Smith MA; Lock RB; Maris JM, 2018, 'Abstract LB-B14: Pediatric Preclinical Testing Consortium evaluation of the second-generation selective inhibitor of nuclear export (SINE) compound KPT-8602', in Molecular Cancer Therapeutics, American Association for Cancer Research (AACR), pp. lb-b14-lb-b14, http://dx.doi.org/10.1158/1535-7163.targ-17-lb-b14

Lock RB; Evans K; Yung R; Pritchard T; Teicher BA; Duan J; Guo Y; Erickson SW; Smith MA, 2018, 'Abstract LB-B16: The AKR1C3-Activated Prodrug OBI-3424 Exerts Profound In Vivo Efficacy Against Preclinical Models of T-Cell Acute Lymphoblastic Leukemia (T-ALL); a Pediatric Preclinical Testing Consortium Study', in Molecular Cancer Therapeutics, American Association for Cancer Research (AACR), pp. lb-b16-lb-b16, http://dx.doi.org/10.1158/1535-7163.targ-17-lb-b16

Wakefield C; Quinn V; Doolan E; Fardell J; Tucker K; Patenaude A; Marshall K; Lock R; Signorelli C; Georgiou G; Cohn R, 2017, 'The use of Murine Models of Chemosensitivity to Anticancer Agents in Childhood Cancer Clinical Care: Survivor, Parent and Community Acceptability and Willingness-to-Pay', in PEDIATRIC BLOOD & CANCER, WILEY, pp. S60 - S61, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000408978201113&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Somers K; Middlemiss S; Biktasova A; Karsa M; Cheung L; Kosciolek A; Evans K; Mayoh C; Kees UR; Korotchkina L; Chernova OB; Lock RB; Gudkov AV; Haber M; Norris MD; Henderson MJ, 2017, 'Abstract 1175: Inhibition of NAMPT as a novel therapeutic strategy for infant leukemia', in Cancer Research, American Association for Cancer Research (AACR), pp. 1175 - 1175, http://dx.doi.org/10.1158/1538-7445.am2017-1175

Evans K; Pritchard T; Henderson MJ; Somers K; Karsa M; Cheung L; Yung R; Erickson SW; Korotchkina L; Chernova O; Gudkov A; Smith MA; Lock RB, 2017, 'Abstract 1942: The nicotinamide phosphoribosyltransferase (NAMPT) inhibitor, OT-82, exhibits in vitro and in vivo efficacy against patient-derived xenograft models of high-risk acute lymphoblastic leukemia', in Cancer Research, American Association for Cancer Research (AACR), pp. 1942 - 1942, http://dx.doi.org/10.1158/1538-7445.am2017-1942

Li KL; Bray SC; Iarossi D; Adams J; Zhong L; Noll B; Rahaman MH; Richmond J; To LB; Lewis ID; Lock RB; Wang S; D'Andrea RJ, 2015, 'Investigation of a Novel Cyclin-Dependent-Kinase (CDK) Inhibitor Cdki-73 As an Effective Treatment Option for MLL-AML', in Blood, American Society of Hematology, pp. 1365, http://dx.doi.org/10.1182/blood.v126.23.1365.1365

Smith MA; Lock R; Carol H; Maris JM; Gorlick R; Kolb EA; Keir ST; Wu J; Landesman Y; Shacham S; Lyalin D; Kurmasheva RT; Houghton PJ, 2015, 'Abstract 1616: Pharmacodynamic and genomic markers associated with response to the XPO1/CRM1 inhibitor selinexor (KPT-330): a report from the Pediatric Preclinical Testing Program', in Cancer Research, American Association for Cancer Research (AACR), pp. 1616 - 1616, http://dx.doi.org/10.1158/1538-7445.am2015-1616

Richmond J; Evans K; Robbins A; Kurmasheva RT; Houghton PJ; Smith MA; Lock RB, 2015, 'Abstract 1620: In vivo and in vitro efficacy of birinapant in preclinical models of Ph-like pediatric acute lymphoblastic leukemia', in Cancer Research, American Association for Cancer Research (AACR), pp. 1620 - 1620, http://dx.doi.org/10.1158/1538-7445.am2015-1620

Jones L; Richmond J; Evans K; Lock RB, 2015, 'Abstract 1631: Bioluminescence imaging enhances analysis of drug response in a patient-derived xenograft model of pediatric acute lymphoblastic leukemia', in Cancer Research, American Association for Cancer Research (AACR), pp. 1631 - 1631, http://dx.doi.org/10.1158/1538-7445.am2015-1631

Smith MA; Kang M; Reynolds PC; Lock RB; Carol H; Gorlick R; Kolb AE; Maris JM; Keir ST; Billups CA; Kurmasheva R; Houghton PJ, 2015, 'Abstract 1615: Initial testing (stage 1) of the Curaxin, CBL0137, by the Pediatric Preclinical Testing Program (PPTP)', in Cancer Research, American Association for Cancer Research (AACR), PA, Philadelphia, pp. 1615 - 1615, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.am2015-1615

Dolnikov A; Rossi S; Xu N; Klamer G; Shen S; Micklethwaite KP; Lock RB; O’Brien T, 2014, '5-Aza-2′-Deoxycytidine Promotes Cytotoxic Effect of CART-Cells on Leukaemia Cells', in Blood, American Society of Hematology, pp. 5812, http://dx.doi.org/10.1182/blood.v124.21.5812.5812

Maude SL; Dolai S; Delgado-Martin C; Hunger SP; Loh ML; Mullighan CG; Hermiston ML; Grupp SA; Lock R; Teachey DT, 2014, 'EARLY T-CELL PRECURSOR (ETP) ACUTE LYMPHOBLASTIC LEUKEMIA IS CHARACTERIZED BY ABERRANT ACTIVATION OF THE JAK/STAT PATHWAY AND PROFOUND RESPONSES TO RUXOLITINIB IN XENOGRAFT MODELS', in PEDIATRIC BLOOD & CANCER, WILEY-BLACKWELL, pp. S109 - S109, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000343932100014&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Suryani S; Carol H; Frimantas V; Bornhauser B; Sarmah C; Chonghaile T; Evans K; Tonna E; Jones L; Letai A; Bourquin J-P; Houghton PJ; Smith MA; Lock RB, 2014, 'Abstract B26: Cell and molecular determinants of in vivo efficacy of the BH3 mimetic ABT-263 against pediatric acute lymphoblastic leukemia xenografts', in Cancer Research, American Association for Cancer Research (AACR), pp. b26 - b26, http://dx.doi.org/10.1158/1538-7445.pedcan-b26

Smith M; Kang M; Reynolds P; Lock R; Carol H; Gorlick R; Kolb A; Maris J; Keir S; Wu J; Kurmasheva R; Houghton P, 2014, '410 Pediatric Preclinical Testing Program (PPTP) Evaluation of the p53-MDM2 Antagonist MK-8242', in European Journal of Cancer, Elsevier, pp. 131, http://dx.doi.org/10.1016/s0959-8049(14)70536-2

Houghton P; Lock R; Carol H; Gorlick R; Kolb A; Maris J; Keir S; Wu J; Kang M; Reynolds P; Kurmasheva R; Smith M, 2014, '412 The Pediatric Preclinical Testing Program (PPTP): Analysis of the first 10 years in vivo testing', in European Journal of Cancer, Elsevier, pp. 131 - 132, http://dx.doi.org/10.1016/s0959-8049(14)70538-6

Lock RB; Richmond J; High L; Carol H; Evans K; Mendomo AM; Kurmasheva RT; Houghton PJ; Smith MA, 2013, 'Effective Targeting Of The P53/MDM2 Axis In Preclinical Models Of Infant MLL-Rearranged Acute Lymphoblastic Leukemia', in Blood, American Society of Hematology, pp. 71, http://dx.doi.org/10.1182/blood.v122.21.71.71

Thomas D; Powell JA; Parker MW; Ekert PG; Lock RB; Huang DC; Nilsson SK; Recher C; Wei AH; Guthridge MA, 2013, 'The selective targeting of cell survival pathways in leukemia', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.FBCR13-A19

Shahbazi J; Lock R; Liu T, 2013, 'BET bromodomain inhibition as a therapeutic strategy to target N-Myc in neuroblastoma', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, NETHERLANDS, Amsterdam, pp. S356 - S356, presented at European Cancer Congress 2013 - 17th ECCO / 38th ESMO / 32nd ESTRO, NETHERLANDS, Amsterdam, 27 September 2013 - 01 October 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000326843602301&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Moradi Manesh D; Carol H; Evans K; Richmond J; Jamieson S; Wilson WR; Houghton PJ; Smith MA; Lock RB, 2013, 'Abstract 2745: AKR1C3 is a potential biomarker of T-cell acute lymphoblastic leukemia sensitivity to the pre-prodrug PR-104.', in Cancer Research, American Association for Cancer Research (AACR), pp. 2745 - 2745, http://dx.doi.org/10.1158/1538-7445.am2013-2745

Houghton PJ; Kang M; Reynolds CP; Lock RB; Carol H; Gorlick R; Kolb EA; Maris JM; Keir ST; Billups CA; Kurmasheva RT; Smith MA, 2013, 'Abstract 2754: Pediatric Preclinical Testing Program (PPTP) stage 1 evaluation of the antimicrotubule agents cabazitaxel and docetaxel.', in Cancer Research, American Association for Cancer Research (AACR), pp. 2754 - 2754, http://dx.doi.org/10.1158/1538-7445.am2013-2754

Houghton P; Kang MH; Reynolds P; Lock R; Carol H; Gorlick R; Kolb A; Maris J; Keir S; Billups C; Kurmasheva R; Smith M, 2013, 'Abstract 2758: Pediatric preclinical testing program (PPTP) stage 1 evaluation of MLN0128, a potent TOR kinase inhibitor.', in Cancer Research, American Association for Cancer Research (AACR), pp. 2758 - 2758, http://dx.doi.org/10.1158/1538-7445.am2013-2758

Toscan C; Failes T; Arndt G; Lock R, 2013, 'Abstract 4550: High throughput screen to identify compounds that reverse glucocorticoid resistance in pediatric leukemia.', in Cancer Research, American Association for Cancer Research (AACR), pp. 4550 - 4550, http://dx.doi.org/10.1158/1538-7445.am2013-4550

Houghton P; Kang M; Reynolds P; Gorlick R; Kolb A; Maris J; Keir S; Carol H; Lock R; Billups C; Kurmasheva R; Landesman Y; Shacham S; Kauffman M; Smith MA, 2013, 'Abstract LB-354: Pediatric Preclinical Testing Program (PPTP) stage 1 evaluation of the XPO1/CRM1 inhibitor KPT-330.', in Cancer Research, American Association for Cancer Research (AACR), pp. lb-354-lb-354, http://dx.doi.org/10.1158/1538-7445.am2013-lb-354

Smith MA; Carol H; Evans K; Richmond J; Kang M; Reynolds CP; Chunduru S; Graham MA; Geier B; Kurmasheva R; Houghton PJ; Lock RB, 2012, 'Birinapant (TL32711), a Small Molecule Smac Mimetic, Induces Regressions in Childhood Acute Lymphoblastic Leukemia (ALL) Xenografts That Express TNFα and Synergizes with TNFα in Vitro – A Report From the Pediatric Preclinical Testing Program (PPTP)', in Blood, American Society of Hematology, GA, Atlanta, pp. 3565, presented at 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), GA, Atlanta, 08 December 2012 - 11 December 2012, http://dx.doi.org/10.1182/blood.v120.21.3565.3565

Lee EM; Yee D; Busfield SJ; Vairo G; Lock RB, 2012, 'A Neutralizing Antibody (CSL362) Against the Interleukin-3 Receptor α-Chain Augments the Efficacy of a Cytarabine/Daunorubicin Induction-Type Therapy in Preclinical Xenograft Models of Acute Myelogenous Leukemia', in Blood, American Society of Hematology, pp. 3599, http://dx.doi.org/10.1182/blood.v120.21.3599.3599

Busfield SJ; Biondo M; Wong M; Ramshaw HS; Lee EM; Martin K; Ghosh S; Braley H; Tomasetig V; Panousis C; Vairo G; Roberts AW; He SZ; Sprigg N; Thomas D; DeWitte M; Lock RB; Lopez AF; Nash A, 2012, 'CSL362: A Monoclonal Antibody to Human Interleukin-3 Receptor (CD123), Optimized for NK Cell-Mediated Cytotoxicity of AML Stem Cells', in Blood, American Society of Hematology, pp. 3598, http://dx.doi.org/10.1182/blood.v120.21.3598.3598

Suryani S; Sia KC; Bracken L; Carol H; Evans K; Kurmasheva R; Houghton PJ; Smith MA; Lock RB, 2012, 'Dual Inhibition of JAK/STAT and MAPK Pathways Results in Synergistic Cell Killing of JAK-Mutated Pediatric Acute Lymphoblastic Leukemia', in Blood, American Society of Hematology, pp. 3562, http://dx.doi.org/10.1182/blood.v120.21.3562.3562

Smith M; Kang M; Lock R; Carol H; Gorlick R; Kolb A; Maris J; Keir S; Kurmasheva R; Houghton P, 2012, '345 Pediatric Preclinical Testing Program (PPTP) Stage 1 Evaluation of Eribulin', in European Journal of Cancer, Elsevier, IRELAND, European Org Res & Treatment Canc (EORTC), Dublin, pp. 105, presented at 24th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, IRELAND, European Org Res & Treatment Canc (EORTC), Dublin, 06 November 2012 - 09 November 2012, http://dx.doi.org/10.1016/s0959-8049(12)72143-3

Smith M; Keir S; Maris J; Kolb A; Reynolds P; Kang M; Carol H; Lock R; Gorlick R; Kurmasheva R; Billups C; Houghton P, 2012, 'Abstract LB-317: Pediatric Preclinical Testing Program (PPTP) evaluation of volasertib (BI 6727), a Polo-like kinase (PLK) inhibitor', in Cancer Research, American Association for Cancer Research (AACR), pp. lb-317-lb-317, http://dx.doi.org/10.1158/1538-7445.am2012-lb-317

Carol H; Lock R; Maris J; Keir S; Gorlick R; Kolb A; Kang M; Reynolds P; Wu J; Kurmasheva R; Houghton P; Smith M, 2012, 'Abstract LB-318: Pediatric Preclinical Testing Program (PPTP) evaluation of the JAK inhibitor AZD1480', in Cancer Research, American Association for Cancer Research (AACR), pp. lb-318-lb-318, http://dx.doi.org/10.1158/1538-7445.am2012-lb-318

Lu H; Battula VL; Shi Y; Lock RB; Spong S; Andreeff M; Konopleva M, 2011, 'Role of Connective Tissue Growth Factor (CTGF) in Survival and Chemosensitivity of Acute Lymphoblastic Leukemia', in BLOOD, AMER SOC HEMATOLOGY, CA, San Diego, pp. 1113 - 1113, presented at 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, CA, San Diego, 10 December 2011 - 13 December 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000299597103459&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Smith MA; Kang MH; Reynolds CP; Lock RB; Carol H; Gorlick R; Kolb EA; Maris JM; Keir ST; Billups CA; Kurmasheva RT; Houghton PJ, 2011, 'Abstract C103: Pediatric Preclinical Testing Program (PPTP) Stage 1 evaluation of the p53-MDM2 antagonist RG7112: Early evidence for high activity against MLL-rearranged leukemias.', in Molecular Cancer Therapeutics, American Association for Cancer Research (AACR), pp. c103 - c103, http://dx.doi.org/10.1158/1535-7163.targ-11-c103

Houghton PJ; Maris JM; Keir ST; Lock RB; Carol H; Gorlick R; Kolb EA; Kang MH; Reynolds CP; Kurmasheva RT; Whiteman KR; Smith MA, 2011, 'Abstract C105: Pediatric Preclinical Testing Program (PPTP) Stage 1 evaluation of the CD56-targeting antibody-drug conjugate lorvotuzumab mertansine.', in Molecular Cancer Therapeutics, American Association for Cancer Research (AACR), pp. c105 - c105, http://dx.doi.org/10.1158/1535-7163.targ-11-c105

Reynolds CP; Kang MH; Carol H; Lock RB; Gorlick R; Kolb EA; Alexander D; Kurmasheva RT; Keir ST; Maris JM; Wu J; Houghton PJ; Smith MA, 2011, 'Abstract C106: Pediatric Preclinical Testing Program (PPTP) Stage 1 evaluation of the PI3K inhibitor XL147 (SAR245408).', in Molecular Cancer Therapeutics, American Association for Cancer Research (AACR), pp. c106 - c106, http://dx.doi.org/10.1158/1535-7163.targ-11-c106

Lock RB; Carol H; Szymanska B; Boehm I; Evans K; Houghton PJ; Smith MA, 2011, 'Abstract C107: The anti-CD19 antibody-drug conjugate SAR3419 prevents hematolymphoid relapse post induction therapy in preclinical models of pediatric acute lymphoblastic leukemia.', in Molecular Cancer Therapeutics, American Association for Cancer Research (AACR), pp. c107 - c107, http://dx.doi.org/10.1158/1535-7163.targ-11-c107

Keir ST; Morton CL; Kolb EA; Gorlick R; Carol H; Lock R; Kang MH; Reynolds CP; Maris JM; Wu J; Smith MA; Houghton PJ, 2011, 'Abstract 5356: Pediatric preclinical testing program (PPTP) evaluation of the DNA methylating agent temozolomide', in Cancer Research, American Association for Cancer Research (AACR), pp. 5356 - 5356, http://dx.doi.org/10.1158/1538-7445.am2011-5356

Carol H; Lock RB; Maris JM; Keir ST; Gorlick R; Kolb EA; Kang MH; Reynolds CP; Morton CL; Smith PG; Thomas M; McDonald A; Houghton PJ; Smith MA, 2011, 'Abstract 740: Pediatric Preclinical Testing Program (PPTP) evaluation of the NEDD8-activating enzyme (NAE) inhibitor MLN4924', in Cancer Research, American Association for Cancer Research (AACR), pp. 740 - 740, http://dx.doi.org/10.1158/1538-7445.am2011-740

Lu H; Battula VL; Korchin B; Spong S; Canizales M; Lock RB; Andreeff M; Konopleva M, 2010, 'Targeting Connective Tissue Growth Factor (CTGF) In Acute Lymphoblastic Leukemia Pre-Clinical Models: Anti-CTGF Monoclonal Antibody Attenuates Tumor Growth In Mouse Models of ALL', in BLOOD, AMER SOC HEMATOLOGY, FL, Orlando, pp. 1335 - 1336, presented at 52nd Annual Meeting of the American-Society-of-Hematology (ASH), FL, Orlando, 04 December 2010 - 07 December 2010, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000289662203588&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

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