By Professor Robert M Graham

Journal articles

Hess HJ; Graham RM; Homcy CJ, 1983, 'Photoaffinity label for the α1-adrenergic receptor: Synthesis and effects on membrane and affinity-purified receptors', Proceedings of the National Academy of Sciences of the United States of America, 80, pp. 2102 - 2106, http://dx.doi.org/10.1073/pnas.80.8.2102

Graham RM; Hess HJ; Homcy CJ, 1982, 'Biophysical characterization of the purified α1-adrenergic receptor and identification of the hormone binding subunit', Journal of Biological Chemistry, 257, pp. 15174 - 15181

Graham RM; Hess HJ; Haber E; Homcy CJ, 1982, 'Antibodies to the alpha1- and alpha2-selective antagonists prazosin and yohimbine as probes of the alpha-adrenergic binding sites', Hypertension, 4, pp. 183 - 187, http://dx.doi.org/10.1161/01.HYP.4.3.183

Graham RM; Hess HJ; Haber E; Homcy CJ, 1982, 'Antibodies to the alpha1- and alpha2-selective antagonists prazosin and yohimbine as probes of the alpha-adrenergic binding sites', Hypertension, 4, pp. 183 - 187, http://dx.doi.org/10.1161/01.HYP.4.3.183

Homcy CJ; Graham RM; Haber E; Hess HJ, 1982, 'Characterization of the purified mammalian α- and β-adrenergic receptors reveals homologous molecular properties', Clinical Research, 30, pp. 482

Graham RM; Campbell WB; Jackson EK, 1982, 'Effects of short-term beta blockade on blood pressure, plasma thromboxane B2, and plasma and urinary prostaglandins E2 and F2α in normal subjects', Clinical Pharmacology and Therapeutics, 31, pp. 324 - 329, http://dx.doi.org/10.1038/clpt.1982.41

Hess HJ; Graham RM; Homcy CJ, 1982, 'Photoaffinity label of the α1-adrenergic receptor (α1AR): Synthesis and effects on rat hepatic membrane (M) and affinity purified (P) receptors', Federation Proceedings, 41

Graham RM; Pettinger WA; Sagalowsky A; Brabson J; Gandler T, 1982, 'Renal alpha-adrenergic receptor abnormality in the spontaneously hypertensive rat', Hypertension, 4, pp. 881 - 887, http://dx.doi.org/10.1161/01.HYP.4.6.881

Homey C; Sylvestre D; Graham R, 1982, 'Solubilization and characterization of the mammalian β2-receptor (βR) in 8M urea', Federation Proceedings, 41, pp. 6774

Graham RM; Hess HJ; Homcy CJ, 1982, 'Solubilization and purification of the α1-adrenergic receptor using a novel affinity resin', Proceedings of the National Academy of Sciences of the United States of America, 79, pp. 2186 - 2190, http://dx.doi.org/10.1073/pnas.79.7.2186

Campbell WB; Callahan KS; Johnson AR; Graham RM, 1981, 'ANTI-PLATELET ACTIVITY OF BETA-ADRENERGIC ANTAGONISTS: INHIBITION OF THROMBOXANE SYNTHESIS AND PLATELET AGGREGATION IN PATIENTS RECEIVING LONG-TERM PROPRANOLOL TREATMENT', Lancet, 318, pp. 1382 - 1384, http://dx.doi.org/10.1016/S0140-6736(81)92800-2

Schmitz JM; Graham RM; Sagalowsky A; Pettinger WA, 1981, 'Renal alpha-1 and alpha-2 adrenergic receptors: Biochemical and pharmacological correlations', Journal of Pharmacology and Experimental Therapeutics, 219, pp. 400 - 406

Campbell WB; Holland OB; Gomez-Sanchez CE; Graham RM; Pettinger WA; White AC, 1981, 'Plasma substance p levels in normotensive and hypertensive subjects', Clinical and Experimental Hypertension, 3, pp. 183 - 193, http://dx.doi.org/10.3109/10641968109033659

Blomqvist CG; Lewis SF; Taylor WF; Graham RM, 1981, 'Similarity of the hemodynamic responses to static and dynamic exercise of small muscle groups', Circulation Research, 48, pp. I-87-I-92

Graham RM; Hess HJ; Homcy C, 1981, 'Solubilization and purification of α-adrenergic receptors utilizing a novel affinity technique', Federation Proceedings, 40, pp. 1630

Graham RM; Campbell WB, 1981, 'Speculative approaches in hypertension: Concepts and drugs of the future', Federation Proceedings, 40, pp. 2291 - 2295

Graham RM; Stephenson WH; Pettinger WA, 1980, 'Pharmacological evidence for a functional role of the prejunctional alpha-adrenoreceptor in noradrenergic neurotransmission in the conscious rat', Naunyn Schmiedeberg S Archives of Pharmacology, 311, pp. 129 - 138, http://dx.doi.org/10.1007/BF00510251

Graham RM; Mulvihill-Wilson J, 1980, 'Clinical pharmacology of prazosin used alone or in combination in the therapy of hypertension', Journal of Cardiovascular Pharmacology, 2, pp. S387 - S398, http://dx.doi.org/10.1097/00005344-198002003-00012

Mulvihill-Wilson J; Graham RM; Pettttinger WA; Muckleroy C; Anderson S; Gaffney F; Blomqvist CG, 1980, 'Comparación de los efectos de prazosin y fenoxibenzamina sobre presión arterial, frecuencia cardiaca y catecolaminas plasmáticas en la hipertensión arterial esencial', Cardiology Switzerland, 66, pp. 85 - 93, http://dx.doi.org/10.1159/000173013

CAMPBELL WB; GRAHAM RM; JACKSON EK; LOISEL DP; PETTINGER WA, 1980, 'EFFECT OF INDOMETHACIN ON HYDRALAZINE‐INDUCED RENIN AND CATECHOLAMINE RELEASE IN THE CONSCIOUS RABBIT', British Journal of Pharmacology, 71, pp. 529 - 531, http://dx.doi.org/10.1111/j.1476-5381.1980.tb10968.x

Boyar RM; Fixler DF; Kaplan NM; Graham RM; Price KP; Chipman JJ; Pennock Laird W, 1980, 'Effects of clonidine on 24-hour hormonal secretory patterns, cardiovascular hemodynamics, and central nervous function in hypertensive adolescents', Hypertension, 2, pp. 83 - 89, http://dx.doi.org/10.1161/01.HYP.2.1.83

Campbell WB; Graham RM; Jackson EK, 1980, 'Inhibition of hydralazine-induced renin release by indomethacin in the rat', Archives Internationales De Pharmacodynamie Et De Therapie, 246, pp. 315 - 323

Mukherjee A; Graham RM; Sagalowsky AI; Pettinger W; McCoy KE, 1980, 'Myocardial beta-adrenergic receptors in the stroke-prone spontaneously hypertensive rat', Journal of Molecular and Cellular Cardiology, 12, pp. 1263 - 1272, http://dx.doi.org/10.1016/0022-2828(80)90070-X

Mitchell HC; Graham RM; Pettinger WA, 1980, 'Renal function during long-term treatment of hypertension with minoxidil. Comparison of benign and malignant hypertension', Annals of Internal Medicine, 93, pp. 676 - 681, http://dx.doi.org/10.7326/0003-4819-93-5-676

Huysmans FTM; Thien T; Koene RAP; Graham RM; Pettinger WA, 1979, 'Hypotensive Action of Prazosin', New England Journal of Medicine, 300, pp. 1335 - 1336, http://dx.doi.org/10.1056/NEJM197906073002316

Koch-Weser J; Graham RM; Pettinger WA, 1979, 'Prazosin', New England Journal of Medicine, 300, pp. 232 - 236, http://dx.doi.org/10.1056/NEJM197902013000505

Mulvihill-Wilson J; Graham RM; Pettinger W; Muckleroy C; Anderson S; Andrew Gaffney F; Gunner Blomqvist C, 1979, 'Comparative effects of prazosin and phenoxybenzamine on arterial blood pressure, heart rate, and plasma catecholamines in essential hypertension', Journal of Cardiovascular Pharmacology, 1, pp. S1 - S7, http://dx.doi.org/10.1097/00005344-197900011-00001

Sagalowsky AI; Graham RM; Schmitz JM; Pettinger WA, 1979, 'Comparison of pharmacologic and biochemical characteristics of renal alpha receptors', Clinical Research, 27, pp. 783

Graham RM; Pettinger WA, 1979, 'Effects of prazosin and phentolamine on arterial pressure, heart rate, and renin activity: Evidence in the conscious rat for the functional significance of the presynaptic α-receptor', Journal of Cardiovascular Pharmacology, 1, pp. 497 - 502, http://dx.doi.org/10.1097/00005344-197909000-00002

Stokes GS; Frost GW; Graham RM; MacCarthy EP, 1979, 'Indoramin and prazosin as adjuncts to beta-adrenoreceptor blockade in treatment of hypertension', Clinical and Experimental Pharmacology and Physiology, 6, pp. 669

Stokes GS; Frost GW; Graham RM; MacCarthy EP, 1979, 'Indorarnin and prazosin as adjuncts to beta adrenoceptor blockade in hypertension', Clinical Pharmacology and Therapeutics, 25, pp. 783 - 789, http://dx.doi.org/10.1002/cpt1979256783

Graham RM; Campbell WB; Jackson EK, 1979, 'Role of prostaglandins in hydralazine-induced renin and catecholamine release in conscious rabbits', Federation Proceedings, 38

Campbell WB; Graham RM; Jackson EK, 1979, 'Role of renal prostaglandins in sympathetically mediated renin release in the rat', Journal of Clinical Investigation, 64, pp. 448 - 456, http://dx.doi.org/10.1172/JCI109482

Mulvihill-Wilson JM; Graham RM; Pettinger WA, 1979, 'Role of selective blockade of α-adrenergic receptors in the antihypertensive effects of α-receptor antagonists in man', Clinical Research, 27, pp. 782

Campbell WB; Jackson EK; Graham RM, 1979, 'Saralasin-induced renin release: Blockade by prostaglandin synthesis inhibitors', Federation Proceedings, 38, pp. no.3440

Campbell WB; Jackson EK; Graham RM, 1979, 'Saralasin-induced renin release: Its blockade by prostaglandin synthesis inhibitors in the conscious rat', Hypertension, 1, pp. 637 - 642, http://dx.doi.org/10.1161/01.HYP.1.6.637

Mulvihill-Wilson J; Graham RM; Pettinger W; Muckleroy C; Anderson S; Gaffney FA; Blomqvist CG, 1979, 'Comparative Effects of Prazosin and Phenoxybenzamine on Arterial Blood Pressure, Heart Rate, and Plasma Catecholamines in Essential Hypertension', Journal of Cardiovascular Pharmacology, 1, pp. S1 - 7, http://dx.doi.org/10.1097/00005344-197911001-00001

Oates HF; Graham RM; Stokes GS, 1978, 'Contrasting actions of four peripherally acting antihypertensive drugs', Clinical and Experimental Pharmacology and Physiology, 5, pp. 244

Graham RM; Kennedy P; Stephenson W; Pettinger WA, 1978, 'In vivo evidence for the presynaptic α-adrenergic receptor controlling norepinephrine release', Federation Proceedings, 37

Graham RM; Brabson JH; Stephenson WH; Pettinger WA, 1978, 'Increased renal α-adrenergic receptors in genetically hypertensive rats', Clinical Research, 26, pp. 363

Bartzokas CA; McCarthy K; Baker BF; Graham R, 1978, 'Observations of the effects of formaldehyde on cockroaches and their flora: III. The effect of formaldehyde in eliminating the normal gut flora', Journal of Hygiene, 80, pp. 137 - 141, http://dx.doi.org/10.1017/S0022172400053468

Graham RM; Brabson JH; Stephenson WH; Pettinger WA, 1978, 'Renal α-adrenergic receptors and hypertension', Circulation, 58

Graham RM; Oates HF; Stoker LM; Stokes GS, 1977, 'Alpha blocking action of the antihypertensive agent, prazosin', Journal of Pharmacology and Experimental Therapeutics, 201, pp. 747 - 752

Oates HF; Graham RM; Stokes GS, 1977, 'Mechanism of the hypotensive action of prazosin', Archives Internationales De Pharmacodynamie Et De Therapie, 227, pp. 41 - 48

Weber MA; Graham RM; Gain JM; Stokes GS, 1977, 'Pharmacological stimulation of renin secretion within the kidney', Archives Internationales De Pharmacodynamie Et De Therapie, 227, pp. 343 - 350

Stokes GS; Graham RM; Gain JM; Davis PR, 1977, 'Influence of dosage and dietary sodium on the first-dose effects of prazosin', British Medical Journal, 1, pp. 1507 - 1508, http://dx.doi.org/10.1136/bmj.1.6075.1507

Graham RM; Gain JMW; Stokes GS, 1977, 'The Use of Clonidine by Intramuscular Injection in the Treatment of Hypertension', Australian and New Zealand Journal of Medicine, 7, pp. 131 - 133, http://dx.doi.org/10.1111/j.1445-5994.1977.tb04678.x

Graham RM; Oates HF; Weber MA; Stokes GS, 1976, 'Suppression of renin release by timolol', Archives Internationales De Pharmacodynamie Et De Therapie, 219, pp. 205 - 210

Graham RM; Sebel EF; Stokes GS, 1976, 'Surgical intervention in severe and complicated renal hypertension: Report of the Sydney Renal Hypertension Group (1969-75)', Clinical Science and Molecular Medicine, 51, pp. 231 - 233

Graham RM; Muir MR; Hayes JM, 1976, 'DIFFERING EFFECTS OF THE VASODILATOR DRUGS, PRAZOSIN AND DIAZOXIDE ON PLASMA RENIN ACTIVITY IN THE DOG', Clinical and Experimental Pharmacology and Physiology, 3, pp. 173 - 177, http://dx.doi.org/10.1111/j.1440-1681.1976.tb00602.x

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