By Professor Robert M Graham

Journal articles

De Young MB; Keller JC; Graham RM; Wildey GM, 1994, 'Brefeldin A defines distinct pathways for atrial natriuretic factor secretion in neonatal rat atrial and ventricular myocytes', Circulation Research, 74, pp. 33 - 40

Perez DM; Piascik MT; Malik N; Gaivin R; Graham RM, 1994, 'Cloning, expression, and tissue distribution of the rat homolog of the bovine α1C-adrenergic receptor provide evidence for its classification as the α1A subtype', Molecular Pharmacology, 46, pp. 823 - 831, http://dx.doi.org/10.1016/s0026-895x(25)09821-9

Graham RM, 1994, 'Cyclosporine: Mechanisms of action and toxicity', Cleveland Clinic Journal of Medicine, 61, pp. 308 - 313, http://dx.doi.org/10.3949/ccjm.61.4.308

Nakaoka H; Perez DM; Baek KJ; Das T; Husain A; Misono K; Im MJ; Graham RM, 1994, 'Gh: A GTP-Binding protein with transglutaminase activity and receptor signaling function', Science, 264, pp. 1593 - 1596, http://dx.doi.org/10.1126/science.7911253

Urata H; Karnik SS; Graham RM; Husain A, 1993, 'Dipeptide processing activates recombinant human prochymase', Journal of Biological Chemistry, 268, pp. 24318 - 24322, http://dx.doi.org/10.1016/s0021-9258(20)80528-6

Perez DM; DeYoung MB; Graham RM, 1993, 'Coupling of expressed α1B- and α1D-adrenergic receptors to multiple signaling pathways is both G protein and cell type specific', Molecular Pharmacology, 44, pp. 784 - 795, http://dx.doi.org/10.1016/s0026-895x(25)13259-8

Graham RM, 1993, 'F. Merlin Bumpus, PhD.', Cleveland Clinic Journal of Medicine, 60, pp. 417 - 418

Ramarao CS; Denker JMK; Perez DM; Gaivin RJ; Riek RP; Graham RM, 1992, 'Genomic organization and expression of the human α(1B)-adrenergic receptor', Journal of Biological Chemistry, 267, pp. 21936 - 21945

Kiuchi K; Vatner DE; Uemura N; Bigaud M; Hasebe N; Hempel DM; Graham RM; Vatner SF, 1992, 'Mechanisms of α1-adrenergic vascular desensitization in conscious dogs', Circulation Research, 71, pp. 1185 - 1199

Franke RR, 1992, 'Structure and function in rhodopsin: Studies of the interaction between the rhodopsin cytoplasmic domain and transducin', Journal of Biological Chemistry, 267, pp. 14767 - 14774

Urata H; Kinoshita A; Perez DM; Misono KS; Bumpus FM; Graham RM; Husain A, 1991, 'Cloning of the gene and cDNA for human heart chymase', Journal of Biological Chemistry, 266, pp. 17173 - 17179, http://dx.doi.org/10.1016/s0021-9258(19)47355-9

Shen YT; Graham RM; Vatner SF, 1991, 'Effects of atrial natriuretic factor on blood flow distribution and vascular resistance in conscious dogs', American Journal of Physiology Heart and Circulatory Physiology, 260, pp. H1893 - H1902, http://dx.doi.org/10.1152/ajpheart.1991.260.6.h1893

Shannon RP; Gelpi RJ; Hittinger L; Vatner DE; Homcy CJ; Graham RM; Vatner SF, 1991, 'Inotropic response to norepinephrine is augmented early and maintained late in conscious dogs with perinephritic hypertension', Circulation Research, 68, pp. 543 - 554, http://dx.doi.org/10.1161/01.RES.68.2.543

Kaye SB; Graham R; McCarthy K; Green JR; Damjanovic V; Austin M, 1991, 'Reducing disinfectant wastage', Eye Basingstoke, 5, pp. 120 - 123, http://dx.doi.org/10.1038/eye.1991.22

Perez DM; Piascik MT; Graham RM, 1991, 'Solution-phase library screening for the identification of rare clones: Isolation of an α1D-adrenergic receptor cDNA', Molecular Pharmacology, 40, pp. 876 - 883

Im MJ; Graham RM, 1990, 'A novel guanine nucleotide-binding protein coupled to the α1-adrenergic receptor: I. Identification by photolabeling of membrane and ternary complex preparations', Journal of Biological Chemistry, 265, pp. 18944 - 18951

Im MJ; Riek RP; Graham RM, 1990, 'A novel guanine nucleotide-binding protein coupled to the α1-adrenergic receptor: II. Purification, characterization, and reconstitution', Journal of Biological Chemistry, 265, pp. 18952 - 18960

Graham RM, 1990, 'Adrenergic receptors: Structure and function', Cleveland Clinic Journal of Medicine, 57, pp. 481 - 492, http://dx.doi.org/10.3949/ccjm.57.5.481

Shen YT; Young MA; Ohanian J; Graham RM; Vatner SF, 1990, 'Atrial natriuretic factor-induced systemic vasoconstriction in conscious dogs, rats, and monkeys', Circulation Research, 66, pp. 647 - 661, http://dx.doi.org/10.1161/01.RES.66.3.647

Terman BI; Riek RP; Grodski A; Hess HJ; Graham RM, 1990, 'Identification and structural characterization of α1-adrenergic receptor subtypes', Molecular Pharmacology, 37, pp. 526 - 534

Wildey GM; Fischman AJ; Margolies MN; Graham RM; Homcy CJ, 1990, 'Phosphorylation state of pro-atrial natriuretic factor in rat atrial secretory granules', Endocrinology, 127, pp. 2839 - 2848

Graham RM, 1989, 'Selective alpha1-adrenergic blockade, lipids, and coronary heart disease risk. Considerations in the treatment of mild hypertension', American Journal of Medicine, 87, pp. S53 - S56, http://dx.doi.org/10.1016/0002-9343(89)90114-9

Forbes AM; Woodrow JC; Verbov JL; Graham RM, 1989, 'Carcinoma of breast and scleroderma: Four further cases and a literature review', Rheumatology, 28, pp. 65 - 69, http://dx.doi.org/10.1093/rheumatology/28.1.65

Parini A; Graham RM, 1989, 'Glycerol, sodium phosphate, and sodium chloride permit the solubilization and partial purification of rat hepatic α1-receptors by 3-(3-cholamidylpropyl)-dimethylammonio-1-propanesulfonate', Analytical Biochemistry, 176, pp. 375 - 381, http://dx.doi.org/10.1016/0003-2697(89)90327-8

Karge WH; Weiner EJ; Kowala MC; Graham RM; Nicolosi RJ, 1989, 'Effects of prazosin on hemodynamics, hemostasis, and serum lipid and lipoprotein levels in normal and hypercholesterolemic monkeys', American Journal of Medicine, 86, pp. 19 - 23, http://dx.doi.org/10.1016/0002-9343(89)90123-X

Parini A; Coupry I; Graham RM; Uzielli I; Atlas D; Lanier SM, 1989, 'Characterization of an imidazoline/guanidinium receptive site distinct from the α2-adrenergic receptor', Journal of Biological Chemistry, 264, pp. 11874 - 11878

MacFarlane AW; Curley RK; Graham RM; Lewis‐Jones MS; King CM, 1989, 'Delayed patch test reactions at days 7 and 9', Contact Dermatitis, 20, pp. 127 - 132, http://dx.doi.org/10.1111/j.1600-0536.1989.tb03121.x

Graham RM, 1989, 'Early, 'late onset' 21-hydroxylase deficiency', British Journal of Dermatology, 121, pp. 95 - 96, http://dx.doi.org/10.1111/j.1365-2133.1989.tb06004.x

Ohanian J; Young MA; Shen YT; Gaivin R; Vatner SF; Graham RM, 1989, 'Natriuretic and diuretic effects of infusion of atrial natriuretic factor in conscious dogs', American Journal of Physiology Renal Fluid and Electrolyte Physiology, 257, pp. F565 - F573, http://dx.doi.org/10.1152/ajprenal.1989.257.4.f565

Aspinall ST; Graham R, 1989, 'Two sources of contamination of a hydrotherapy pool by environmental organisms', Journal of Hospital Infection, 14, pp. 285 - 292, http://dx.doi.org/10.1016/0195-6701(89)90068-6

Young MA; Vatner DE; Knight DR; Graham RM; Homcy CJ; Vatner SF, 1988, 'α-Adrenergic vasoconstriction and receptor subtypes in large coronary arteries of calves', American Journal of Physiology Heart and Circulatory Physiology, 255, pp. 24/6

Wildey GM; Fischman AJ; Fallon JT; Matsueda GR; Zisfein JB; Preibisch G; Seipke G; Homcy CJ; Graham RM, 1988, 'Cellular processing of pro-atrial natriuretic factor (PRO-ANF): Studies using an antiserum that selectively binds anf-(99-126) after its cleavage from pro-anf', Endocrinology, 123, pp. 2054 - 2061, http://dx.doi.org/10.1210/endo-123-4-2054

Graham R; Palmer D; Pratt BC; Hart CA, 1988, 'In vitro activity of florphenicol', European Journal of Clinical Microbiology Infectious Diseases, 7, pp. 691 - 694, http://dx.doi.org/10.1007/BF01964257

LANIER SM; HOMCY CJ; GRAHAM RM, 1988, 'IDENTIFICATION OF STRUCTURALLY DISTINCT ALPHA-2-ADRENERGIC RECEPTORS', CLINICAL RESEARCH, 36, pp. A542 - A542, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1988M818001715&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

LANIER SM; GRAHAM RM; HOMCY CJ, 1988, 'STRUCTURAL VARIATION OF ALPHA-2-ADRENERGIC RECEPTORS', FASEB JOURNAL, 2, pp. A1138 - A1138, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1988M598401108&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Graham RM; Sena LM; Longabaugh JP; Sawutz DG; Schwarz KR; Homcy CJ, 1988, 'Coupling of the α1-adrenergic receptor to a guanine nucleotide-binding regulatory protein by a discrete domain distinct from its ligand recognition site', Bba Molecular Cell Research, 968, pp. 119 - 126, http://dx.doi.org/10.1016/0167-4889(88)90051-1

Supple EW; Graham RM; Powell WJ, 1988, 'Direct effects of α2-adrenergic receptor stimulation on intravascular systemic capacity in the dog', Hypertension, 11, pp. 352 - 359, http://dx.doi.org/10.1161/01.HYP.11.4.352

Svetkey LP; Brobyn R; Deedwania P; Graham RM; Morganroth J; Klotman PE, 1988, 'Double-blind comparison of doxazosin, nadolol, and placebo in patients with mild-to-moderate hypertension', Current Therapeutic Research Clinical and Experimental, 43, pp. 969 - 978

Muntz KH; Calianos TA; Buja LM; Willerson JT; Bernatowicz M; Homcy CJ; Graham RM, 1988, 'Electron microscopic localization of the β-adrenergic receptor using a ferritin-alprenolol probe', Molecular Pharmacology, 34, pp. 444 - 451

Lanier SM; Homcy CJ; Patenaude C; Graham RM, 1988, 'Identification of structurally distinct α2-adrenergic receptors', Journal of Biological Chemistry, 263, pp. 14491 - 14496

Camazine B; Shannon RP; Guerrero JL; Graham RM; Powell WJ, 1988, 'Neurogenic histaminergic vasodilation in canine skeletal muscle: Mediation by α2-adrenoceptor stimulation', Circulation Research, 62, pp. 871 - 883, http://dx.doi.org/10.1161/01.RES.62.5.871

Waldman HM; Palacios IF; Block PC; Wilkins GT; Homcy CJ; Graham RM; Fifer MA, 1988, 'Responsiveness of Plasma Atrial Natriuretic Factor to Short-Term Changes in Left Atrial Hemodynamics After Percutaneous Balloon Mitral Valvuloplasty', Journal of the American College of Cardiology, 12, pp. 649 - 655, http://dx.doi.org/10.1016/S0735-1097(88)80051-2

Fischman AJ; Wildey GM; Matsueda GR; Margolies MN; Zisfein JB; Homcy CJ; Graham RM, 1988, 'Specificity of serine proteases for cleavage sites on proatrial natriuretic factor', Peptides, 9, pp. 1275 - 1283, http://dx.doi.org/10.1016/0196-9781(88)90192-1

Dimsdale J; Ziegler M; Graham R, 1988, 'The effect of hypertension, sodium, and race on isoproterenol sensitivity', Clinical and Experimental Hypertension Part A Theory and Practice, 10, pp. 747 - 756, http://dx.doi.org/10.1080/07300077.1988.11878781

Sawutz DG; Lanier SM; Warren CD; Graham RM, 1987, 'Glycosylation of the mammalian α1-adrenergic receptor by complex type N-linked oligosaccharides', Molecular Pharmacology, 32, pp. 565 - 571

Sawutz DG; Sena LM; Cornett LE; Graham RM, 1987, 'Alpha1-adrenergic receptor photoaffinity labeling in intact cells', Biochemical Pharmacology, 36, pp. 4027 - 4032, http://dx.doi.org/10.1016/0006-2952(87)90477-1

Flanigan T; Shapiro E; Graham R, 1987, 'Prophylaxis against Pneumocystis carinii Pneumonia in Patients Receiving Azidothymidine', New England Journal of Medicine, 317, pp. 1155, http://dx.doi.org/10.1056/NEJM198710293171812

Zisfein JB; Sylvestre D; Homcy CJ; Graham RM, 1987, 'Analysis of atrial natriuretic factor biosynthesis and secretion in adult and neonatal rat atrial cardiocytes', Life Sciences, 41, pp. 1953 - 1959, http://dx.doi.org/10.1016/0024-3205(87)90748-X

LANIER SM; GRAHAM RM; HESS HJ; GRODSKI A; REPASKE MG; NUNNARI JM; LIMBIRD LE; HOMCY CJ, 1987, 'SYNTHESIS AND CHARACTERIZATION OF ARYLAMINE DERIVATIVES OF RAUWOLSCINE AS MOLECULAR PROBES FOR ALPHA-2-ADRENERGIC RECEPTORS', HYPERTENSION, 9, pp. 120 - 124, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1987H882100023&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

SAWUTZ DG; LANIER SM; WARREN CD; HOMCY CJ; GRAHAM RM, 1987, 'CARBOHYDRATE MOIETIES OF THE ALPHA-1-ADRENERGIC RECEPTOR (ALPHA-1-R) COMPLEX TYPE GLYCOSYLATION OF N-LINKED OLIGOSACCHARIDES', FEDERATION PROCEEDINGS, 46, pp. 2194 - 2194, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1987H178701565&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

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