By Professor Robert M Graham

Journal articles

Chih S; Macdonald P; Fenely M; Law M; Graham R; McCrohon J, 2008, 'Reproducibility of Adenosine Stress Cardiac Magnetic Resonance Imaging by Normalised Upslope Analysis in Patients with Severe Coronary Artery Disease', Heart, Lung and Circulation, 17, pp. S47 - S48, http://dx.doi.org/10.1016/j.hlc.2008.05.109

Kovacic JC; Macdonald PS; Feneley MP; Muller DW; Freund J; Dodds AJ; Milliken ST; Tao H; Itescu S; Moore JJ; Ma DD; Graham RM, 2008, 'Safety and efficacy of consecutive cycles of granulocyte-colony stimulating factor, and an intracoronary CD 133(+) cell infusion in patients with chronic refractory ischemic heart disease: The G-CSF in Angina patients with IHD to stimulate Neovascul', American Heart Journal, 156, pp. 954 - 963

Riek RP; Finch A; Begg G; Graham RM, 2008, 'Wide turn diversity in protein transmembrane helices implications for G-protein-coupled receptor and other polytopic membrane protein structure and function', Molecular Pharmacology, 73, pp. 1092 - 1104, http://dx.doi.org/10.1124/mol.107.043042

Kovacic JC; Macdonald P; Feneley MP; Muller DW; Ma D; Tao H; Freund J; Milliken S; Dodds A; Moore J; Itescu S; Graham RM, 2007, 'Abstract 2669: The Use of Granulocyte-Colony Stimulating Factor in Angina Patients to Stimulate Neovascularization: the GAIN I study', Circulation, 116, http://dx.doi.org/10.1161/circ.116.suppl_16.ii_591-d

Jariwala D; Graham RM; Lowry JC, 2007, 'Altered sensation [1]', British Dental Journal, 203, pp. 227, http://dx.doi.org/10.1038/bdj.2007.795

Graham RM; Cousin GCS, 2007, 'Access to the chin [10]', British Dental Journal, 202, pp. 645, http://dx.doi.org/10.1038/bdj.2007.490

Kovacic JC; Muller DW; Graham RM, 2007, 'Actions and therapeutic potential of G-CSF and GM-CSF in cardiovascular disease', Journal of Molecular and Cellular Cardiology, 42, pp. 19 - 33

MacDiarmid J; Mugridge N; Weiss J; Phillips LN; Burn AL; Paulin R; Haasdyk J; Dickson K; Brahmbhatt V; Pattison S; James AC; Al Bakri G; Straw R; Stillman B; Graham RM; Brahmbhatt H, 2007, 'Bacterially derived 400 nm particles for encapsulation and cancer cell targeting of chemotherapeutics', Cancer Cell, 11, pp. 431 - 445

Kovacic JC; Ma DD; Tao H; Herbert AD; Moore JJ; Graham RM, 2007, 'Phenotypic characterization of CD133+cells suggests a potent hemangioblast population', Circulation Research, 101, pp. E55 - E56

Kovacic JC; Macdonald PS; Freund J; Rasko J; Allan RM; Fernandes VB; Ma DD; Moore JJ; Graham RM, 2007, 'Profound thrombocytopenia related to G-CSF', American Journal of Hematology, 82, pp. 229 - 230

Jabbour A; Hayward C; Keogh A; Kotlyar E; Liu X; Zhou MD; Li XY; McCrohon J; Graham RM; Macdonald P, 2007, 'Recombinant Human Neuregulin-1 (rhNRG-1) Improves Cardiac Output in Patients with Stable Chronic Heart Failure', Heart, Lung and Circulation, 16, pp. S13 - S13, http://dx.doi.org/10.1016/j.hlc.2007.06.034

Ju Y; Chu YH; Chaulet H; Lai D; Gervasio OL; Graham RM; Cannells M; Allen DG, 2007, 'Store-Operated Ca2+ Influx and Expression of TRPC Genes in Mouse Sinoatrial Node', Circulation Research, 100 (11), pp. 1605 - 1614

Strnad P; Harada M; Siegel M; Terkeltaub R; Graham RM; Khosla C; Omary M, 2007, 'Transglutaminase 2 regulates mallory body inclusion formation and injury-associated liver enlargement', Gastroenterology, 132, pp. 1515 - 1526

Thomas AC; Cullup T; Norgett EE; Hill T; Barton S; Dale BA; Sprecher E; Sheridan E; Taylor AE; Wilroy RS; DeLozier C; Burrows N; Goodyear H; Fleckman P; Stephens KG; Mehta L; Watson RM; Graham R; Wolf R; Slavotinek A; Martin M; Bourn D; Mein CA; O'Toole EA; Kelsell DP, 2006, 'ABCA12 is the major harlequin ichthyosis gene', Journal of Investigative Dermatology, 126, pp. 2408 - 2413, http://dx.doi.org/10.1038/sj.jid.5700455

Begg GE; Holman SR; Stokes PH; Matthews JM; Graham RM; Iismaa SE, 2006, 'Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity', JOURNAL OF BIOLOGICAL CHEMISTRY, 281, pp. 12603 - 12609, http://dx.doi.org/10.1074/jbc.M600146200

Finch AM; Graham RM, 2006, 'The α1D-adrenergic receptor: Cinderella or ugly stepsister', Molecular Pharmacology, 69, pp. 1 - 4, http://dx.doi.org/10.1124/mol.105.020230

Du XR; Gao X; Kiriazis H; Moore X; Ming Z; Su Y; Wang K; Finch A; Dart A; Graham RM, 2006, 'Cardiac overexpression of the alpha(1A)-adrenergic receptor limits post-infarct ventricular remodeling and dysfunction, and improves survival', Journal of Molecular and Cellular Cardiology, 41, pp. 735 - 735

Iismaa S; Begg G; Graham RM, 2006, 'Cross-linking transglutaminases with G protein-coupled receptor signaling.', Science S Stke, 353, pp. pe34, http://dx.doi.org/10.1126/stke.3532006pe34

Begg G; Carrington L; Stokes P; Matthews JM; Wouters MA; Husain A; Lorand L; Iismaa SE; Graham RM, 2006, 'Mechanism of allosteric regulation of transglutaminase 2 by GTP', Proceedings of the National Academy of Sciences of the United States of America, 103, pp. 19683 - 19688

Begg G; Holman S; Stokes P; Matthews J; Graham RM; Iismaa SE; Holman , 2006, 'Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity', The Journal of Biological Chemistry, 281, pp. 12603 - 12609, http://dx.doi.org/10.1074/jbc.M600146200

Liu X; Gu X; Li Z; Li X; Li H; Chang J; Chen PP; Jin J; Xi B; Chen D; Lai D; Graham RM; Zhou M, 2006, 'Neuregulin-1/erbB-activation improves cardiac function and survival in models of ischemic, dilated, and viral cardiomyopathy', Journal of the American College of Cardiology, 48, pp. 1438 - 1447

Chaulet H; Guo J; Owens WA; Michalicek J; Kesteven SH; Guan Z; Prall OW; Mearns BM; Feneley MP; Steinberg S; Graham RM, 2006, 'Sustained augmentation of cardiac alpha(1A)-adrenergic drive results in pathological remodeling with contractile dysfunction, progressive fibrosis and reactivation of matricellular protein genes', Journal of Molecular and Cellular Cardiology, 40, pp. 540 - 552

Finch A; Graham RM, 2006, 'The alpha(1D)-adrenergic receptor: Cinderella or ugly stepsister', Molecular Pharmacology, 69, pp. 1 - 4

Du X; Gao X; Kiriazis H; Moore X; Ming Z; Su Y; Finch A; Hannan R; Dart A; Graham RM, 2006, 'Transgenic alpha(1A)-adrenergic activation limits post-infarct ventricular remodeling and dysfunction and improves survival', Cardiovascular Research, 71, pp. 735 - 743

Ma DDF; Kovacic JC; Dodds A; Tao H; McDonald P; Feneley MP; Muller DW; Fruend J; Milliken S; Moore J; Itescu S; Graham RM, 2005, 'Granulocyte-Colony Stimulating Factor Decreases Angina and Improves Exercise Capacity in Patients with Chronic Refractory ‘No Option’ Ischemic Heart Disease.', Blood, 106, pp. 4215 - 4215, http://dx.doi.org/10.1182/blood.v106.11.4215.4215

James M; Hoff T; Davis J; Graham R, 2005, 'Grant watch report: Leveraging the power of the media to combat HIV/AIDS: The Kaiser Family Foundation's partnerships with media and others to help educate the public about HIV/AIDS, here and abroad', Health Affairs, 24, pp. 854 - 857, http://dx.doi.org/10.1377/hlthaff.24.3.854

Kovacic JC; Graham RM, 2005, 'Are improvements in cardiac function due to stem cell uptake and engraftment?', American Journal of Cardiology, 95, pp. 159, http://dx.doi.org/10.1016/j.amjcard.2004.07.138

Byrne A; Graham G; Hallinan R; Murnion B; Hulse GK; Arnold-Reed DE; Wodak A; Graham R; Hulse GK, 2005, 'Naltrexone implants as treatment for heroin dependence: Part I (multiple letters)', Addiction Biology, 10, pp. 201, http://dx.doi.org/10.1080/13556210500155789

Naqvi N; Liu K; Graham RM; Husain A; Husain A, 2005, 'Evolutionary origins of exopeptidase activity in the C-domain of human angiotensin I-converting enzyme', Federation of American Societies for Experimantal Biology Journal, 19, pp. A293 - A293, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000227610702070&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Graham RM, 2005, 'Transglutaminases in perspective', Journal of Neurochemistry, 94, pp. 82 - 82, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000231673400221&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Begg G; Iismaa S; Carrington L; Holman S; Graham RM; Holman , 2005, 'Allosteric inactivation of transglutaminase 2 by GTP involves stabilisation of a conformational substate and formation of a critical Cys/Tyr H-bond', Biophysical Journal, 88, pp. 15A - 15A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000226378500064&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Begg G; Iismaa SE; Carrington L; Holman S; Husain A; Graham RM; Holman , 2005, 'Allosteric regulation of the transamidase activity of transglutaminase 2 by guanine nucleotide', FEBS Journal, 272, pp. 408 - 408, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000234826102212&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Ma DD; Kovacic JC; Dodds AJ; Tao H; Mcdonald PS; Feneley MP; Muller DW; Fruend J; Milliken ST; Moore JJ; Itescu S; Graham RM, 2005, 'Granulocyte-colony stimulating factor decreases angina and improves exercise capacity in patients with chronic refractory `no option` ischemic heart disease', Blood, 106, pp. 134B - 134B

Naqvi N; Liu KH; Graham RM; Husain A, 2005, 'Molecular basis of exopeptidase activity in the C-terminal domain ofhuman angiotensin I-converting enzyme - Insights into the origins ofits exopeptidase activity', The Journal of Biological Chemistry, 280, pp. 6669 - 6675

Wodak AD; Graham RM, 2005, 'Naltrexone implants as treatment for heroin dependence: Part II', Addiction Biology, 10, pp. 202 - 202

Kovacic JC; Muller DW; Harvey RJ; Graham RM, 2005, 'Update on the use of stem cells for cardiac disease', Internal Medicine Journal, 35, pp. 348 - 356

Palmieri C; Vigushin D; Coombes RC; Kim HS; Kang HJ; Park YB; Kovacic JC; Graham RM, 2004, 'Stem-cell therapy for myocardial diseases [4] (multiple letters)', Lancet, 363, pp. 1734 - 1735, http://dx.doi.org/10.1016/s0140-6736(04)16268-5

Tan JC; McMahon A; Graham RM; Feneley MP, 2004, 'Cardiac myocyte intracellular calcium handling and contractility inalpha1(A)-adrenergic receptor overexpressing', Journal of Molecular and Cellular Cardiology, 37, pp. 301 - 301, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000222965000464&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Du X; Gao X; Kiriazis H; Hannan R; MacCallum P; Graham RM, 2004, 'Cardiac-restricted overexpression of the alpha(1A)-adrenergic receptor preserves contractile function and limits ventricular remodeling after myocardial infarction', Circulation, 110, pp. 300 - 300

Cocks HJ; Kevans P; Graham RM; Brien JE, 2004, 'Evaluation of Therapeutic Drug Monitoring Services and Comparison of Two Models of Service Provision', Journal of Pharmacy Practice and Research, 34, pp. 109 - 113

Du X; Fang L; Gao X; Kiriazis H; Feng X; Hotchkin E; Finch AM; Chaulet H; Graham RM, 2004, 'Genetic enhancement of ventricular contractility protects against pressure-overload-induced cardiac dysfunction', Journal of Molecular and Cellular Cardiology, 37, pp. 979 - 987

Li M; Michalicek J; Angus JA; Hunt JE; Dell Italia L; Feneley MP; Graham RM; Husain A, 2004, 'Involvement of chymase-mediated angiotensin II generation in blood pressure regulation', Journal of Clinical Investigation, 114, pp. 112 - 120

Hwang K; Lim S; Kwon H; Bae Y; Kang S; Chung K; Graham RM; Rhee S; Jang Y, 2004, 'Phospholipase C-[delta]1 rescues intracellular Ca2+ overload in ischemic heart and hypoxic neonatal cardiomyocytes', Journal of Steroid Biochemistry and Molecular Biology, 91, pp. 131 - 138, http://www.sciencedirect.com/science/article/B6T8X-4CSYKH2-1/2/ddae75a5eacab1a819c826961b301a29

Kovacic JC; Graham RM, 2004, 'Stem-cell therapy for myocardial diseases', The Lancet, 363, pp. 1735 - 1736, http://www.sciencedirect.com/science/article/B6T1B-4CF51H5-16/2/5af11943dcf04c84ca831fb4b99586df

Ju YK; Wu MJ; Chaulet H; Marciniec T; Graham RM; Allen DG, 2003, 'IGF-1 Enhances a Store-Operated Ca²⁺ Channel in Skeletal Muscle Myoblasts: Involvement of a CD20-Like Protein', Journal of Cellular Physiology, 197, pp. 53 - 60, http://dx.doi.org/10.1002/jcp.10347

Sharpe IA; Thomas L; Loughnan M; Motin L; Palant E; Croker DE; Alewood D; Chen S; Graham RM; Alewood P; Adams DJ; Lewis RA, 2003, 'Allosteric á1-adrenoceptor antagonism by the conopeptide ñ-TIA', The Journal of Biological Chemistry, 278, pp. 34451 - 34457, http://dx.doi.org/10.1074/jbc.M305410200

Lin F; Owens AW; Kesteven SH; Michalicek J; Chen S; Graham RM; Feneley MP, 2003, 'Cardiac-targeted overexpression of the α1A-AR results in premature death: A potential model of electromechanical dissociation', Heart, Lung and Circulation, 12, pp. A59 - A59, http://dx.doi.org/10.1046/j.1443-9506.2003.02393.x

Iismaa SE; Graham RM, 2003, 'Dissecting cardiac hypertrophy and signalling pathways: evidence for an interaction between multifunctional G proteins and prostanoids', Corc Res, 92, pp. 1059 - 1061

Johnson K; Van Elten D; Nanda N; Graham RM; Terkeltaub R, 2003, 'Distinct transglutaminase II/TG2-independent and TG2-dependent pathways mediate articular chondrocyte hypertrophy', The Journal of Biological Chemistry, 21, pp. 18824 - 18832

Husain A; Li M; Graham RM, 2003, 'Do studies with ACE N- and C-Fomain-Selective Inhibitors provide evidence for a non-ACE, non-chymase Angiotensin II-forming pathway?', Circ Res, 93, pp. 91 - 93

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